메뉴 건너뛰기




Volumn 70, Issue 5, 1997, Pages 508-511

Rare mutations and no hypermethylation at the CDKN2A locus in epithelial ovarian tumours

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2A; UNCLASSIFIED DRUG;

EID: 0030895616     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970304)70:5<508::AID-IJC3>3.0.CO;2-1     Document Type: Article
Times cited : (43)

References (27)
  • 1
    • 0028820566 scopus 로고
    • LOH and mutation analysis of CDKN2A in primary human ovarian cancers
    • CAMPBELL, I.G., BEYNON, G., DAVIS, M. and ENGLEEIELD, P., LOH and mutation analysis of CDKN2A in primary human ovarian cancers. Int. J. Cancer, 63, 222-225 (1995).
    • (1995) Int. J. Cancer , vol.63 , pp. 222-225
    • Campbell, I.G.1    Beynon, G.2    Davis, M.3    Engleeield, P.4
  • 2
    • 0027963502 scopus 로고
    • Homozygous deletions on the short arm of chromosome 9 in ovarian adenocarcinoma cell lines and loss of heterozygosity in sporadic tumours
    • CHENEVIX-TRENCH, G., KERR, J., FRIEDLANDER, M., HURST, T., SANDERSON, B., COGLAN, M., WARD, B., LEARY, J. and KHOO, S.K., Homozygous deletions on the short arm of chromosome 9 in ovarian adenocarcinoma cell lines and loss of heterozygosity in sporadic tumours. Amer. J. hum. Genet., 55, 143-149 (1994).
    • (1994) Amer. J. Hum. Genet. , vol.55 , pp. 143-149
    • Chenevix-Trench, G.1    Kerr, J.2    Friedlander, M.3    Hurst, T.4    Sanderson, B.5    Coglan, M.6    Ward, B.7    Leary, J.8    Khoo, S.K.9
  • 3
    • 0031014476 scopus 로고    scopus 로고
    • Analysis of loss of heterozygosity and K-ras mutations in ovarian neoplasms: Clinicopathological correlations
    • In press
    • CHENEVIX-TRENCH, G. and 19 OTHERS, Analysis of loss of heterozygosity and K-ras mutations in ovarian neoplasms: clinicopathological correlations. Genes Chromosomes Cancer (1997) (In press).
    • (1997) Genes Chromosomes Cancer
    • Chenevix-Trench, G.1
  • 4
  • 6
    • 0030020856 scopus 로고    scopus 로고
    • High frequency of chromosome 9 deletion in ovarian cancer: Evidence for three tumour-suppressor loci
    • DEVLIN, J., ELDER. P.A., GABRA, H., STEEL, C.M. and KNOWLES, M.A., High frequency of chromosome 9 deletion in ovarian cancer: evidence for three tumour-suppressor loci. Brit. J. Cancer, 73, 420-423 (1996).
    • (1996) Brit. J. Cancer , vol.73 , pp. 420-423
    • Devlin, J.1    Elder, P.A.2    Gabra, H.3    Steel, C.M.4    Knowles, M.A.5
  • 7
    • 0028133292 scopus 로고
    • Homozygous deletion mapping at 9p21 in bladder carcinoma defines a critical region within 2cM of IFNA
    • DEVLIN, J., KEEN, A.J. and KNOWLES, M.A., Homozygous deletion mapping at 9p21 in bladder carcinoma defines a critical region within 2cM of IFNA. Oncogene, 9, 2757-2760 (1994).
    • (1994) Oncogene , vol.9 , pp. 2757-2760
    • Devlin, J.1    Keen, A.J.2    Knowles, M.A.3
  • 12
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/ MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • HERMAN, J.G., MERLO, A., MAO, L., LAPIDUS, R.G., OSSA, J.P.J., DAVIDSON, N.E., SIDRANSKY, D. and BAYLIN, S.B., Inactivation of the CDKN2/p16/ MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res., 55, 4525-1530 (1995).
    • (1995) Cancer Res. , vol.55 , pp. 4525-11530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Ossa, J.P.J.5    Davidson, N.E.6    Sidransky, D.7    Baylin, S.B.8
  • 14
    • 0029082427 scopus 로고
    • Allele-specific loss in chromosome 9p loci in preneoplastic lesions accompanying non-small-cell lune cancers
    • KISHIMOTO, Y., SUGIO, K., HUNG, J.Y., VIRMANU A.K., MCLNTIRE, D.D., MINNA, J.D. and GAZDAR, A.F., Allele-specific loss in chromosome 9p loci in preneoplastic lesions accompanying non-small-cell lune cancers. J. nat. Cancer Inst., 87, 1224-1229 (1995).
    • (1995) J. Nat. Cancer Inst. , vol.87 , pp. 1224-1229
    • Kishimoto, Y.1    Sugio, K.2    Hung, J.Y.3    Virmanu, A.K.4    Mclntire, D.D.5    Minna, J.D.6    Gazdar, A.F.7
  • 15
    • 0029016477 scopus 로고
    • Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region
    • LEGGETT, B.A., YOUNG, J.P., BUTTENSHAW, R., THOMAS, L.R., YOUNG, B., CHENEVIX-TRENCH, G., SEARLE, J. and WARD, M. Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region. Brit. J. Cancer, 71, 1070-1073 (1995).
    • (1995) Brit. J. Cancer , vol.71 , pp. 1070-1073
    • Leggett, B.A.1    Young, J.P.2    Buttenshaw, R.3    Thomas, L.R.4    Young, B.5    Chenevix-Trench, G.6    Searle, J.7    Ward, M.8
  • 17
    • 0029011539 scopus 로고
    • 5′CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/ CDKN2/MTS1 in human cancers
    • MERLO, A., HERMAN, J.G., MAO, L., LEE, D.J., GABRIELSON, E., BURGER, P.C., BAYLIN, S.B. and SIDRANSKY, D., 5′CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/ CDKN2/MTS1 in human cancers. Nature (Med.), 1, 686-692 (1995).
    • (1995) Nature (Med.) , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sidransky, D.8
  • 18
    • 0028275733 scopus 로고
    • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • NOBORI, T., MIURA, K., Wu, D.J., Lois, A., TAKABAYASHI, K. and CARSON, D.A., Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (Lond.), 368, 753-756 (1994).
    • (1994) Nature (Lond.) , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayashi, K.5    Carson, D.A.6
  • 19
    • 0029873201 scopus 로고    scopus 로고
    • Infrequent somatic alteration of p16/MTS1 in human primary superficial bladder cancers
    • OKAJIMA, E., FUKUDA, T., OKITA, S., TSUTSUMI, M., HIRAO, Y., OKAJIMA, E. and KONISHI, Y., Infrequent somatic alteration of p16/MTS1 in human primary superficial bladder cancers. Cancer Lett., 203, 227-231 (1996).
    • (1996) Cancer Lett. , vol.203 , pp. 227-231
    • Okajima, E.1    Fukuda, T.2    Okita, S.3    Tsutsumi, M.4    Hirao, Y.5    Okajima, E.6    Konishi, Y.7
  • 20
    • 0028207637 scopus 로고
    • Polymerase chain reaction allelotyping of human ovarian cancer
    • OSBORNE, R.J. and LEECH, V., Polymerase chain reaction allelotyping of human ovarian cancer. Brit. J. Cancer, 69, 429-438 (1994a).
    • (1994) Brit. J. Cancer , vol.69 , pp. 429-438
    • Osborne, R.J.1    Leech, V.2
  • 21
    • 1842350277 scopus 로고
    • Chromosome 9q deletion mapping in epithelial ovarian cancer
    • OSBORNE, R.J. and LEECH, V., Chromosome 9q deletion mapping in epithelial ovarian cancer. Proc. Amer. Assoc. Cancer Res., 35, 601 (1994b).
    • (1994) Proc. Amer. Assoc. Cancer Res. , vol.35 , pp. 601
    • Osborne, R.J.1    Leech, V.2
  • 22
    • 0028787221 scopus 로고
    • CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2′deoxycytidine
    • OTTERSON, G.A., KHLEIF, S.N., CHEN, W., COXON, A.B. and KAYE, F.J., CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2′deoxycytidine. Oncogene, 11, 1211-1216 (1995).
    • (1995) Oncogene , vol.11 , pp. 1211-1216
    • Otterson, G.A.1    Khleif, S.N.2    Chen, W.3    Coxon, A.B.4    Kaye, F.J.5
  • 23
    • 0028850649 scopus 로고
    • Detailed deletion mapping of chromosome 9p and p16 gene alterations in human borderline and invasive epithelial ovarian tumours
    • RODABAUGH, K.J., BIGGS, R.B., QURESHI, J.A., BARRETT, A.J., WILLIAM, R.W., BELL, D.A., BERKOWITZ, R.S. and MOK, S., Detailed deletion mapping of chromosome 9p and p16 gene alterations in human borderline and invasive epithelial ovarian tumours. Oncogene, 11, 1249-1254 (1995).
    • (1995) Oncogene , vol.11 , pp. 1249-1254
    • Rodabaugh, K.J.1    Biggs, R.B.2    Qureshi, J.A.3    Barrett, A.J.4    William, R.W.5    Bell, D.A.6    Berkowitz, R.S.7    Mok, S.8
  • 24
    • 0029024708 scopus 로고
    • Characterization of chromosome 9 in human ovarian neoplasia identifies frequent genetic imbalance on 9q and rare alterations involving 9p, including CDKN2
    • SCHULTZ, D.C., VANDERVEER, L., BUETOW, K.H., BOENTE, M.P., OZOLS, R.F., HAMILTON, T.C. and GODWIN, A.K., Characterization of chromosome 9 in human ovarian neoplasia identifies frequent genetic imbalance on 9q and rare alterations involving 9p, including CDKN2. Cancer Res., 55, 2150-2157 (1995).
    • (1995) Cancer Res. , vol.55 , pp. 2150-2157
    • Schultz, D.C.1    Vanderveer, L.2    Buetow, K.H.3    Boente, M.P.4    Ozols, R.F.5    Hamilton, T.C.6    Godwin, A.K.7
  • 25
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • SERRANO, M., HANNON, G.J. and BEACH, D., A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature (Lond.), 366, 704-707 (1993).
    • (1993) Nature (Lond.) , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.