메뉴 건너뛰기




Volumn 3, Issue 1, 2005, Pages 70-80

Tuberculosis - Metabolism and respiration in the absence of growth

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE;

EID: 11144250804     PISSN: 17401526     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrmicro1065     Document Type: Review
Times cited : (391)

References (90)
  • 1
    • 0012746992 scopus 로고    scopus 로고
    • The growing burden of tuberculosis: Global trends and interactions with the HIV epidemic
    • Corbett, E. L. et al. The growing burden of tuberculosis: global trends and interactions with the HIV epidemic. Arch. Intern. Med. 163, 1009-1021 (2003).
    • (2003) Arch. Intern. Med. , vol.163 , pp. 1009-1021
    • Corbett, E.L.1
  • 2
    • 17644390982 scopus 로고    scopus 로고
    • (eds Rom, W. N. & Garay, S. M.) (Lippincott Williams & Wilkins, Philadelphia)
    • Jagirdar, J. & Zagzag, D. in Tuberculosis (eds Rom, W. N. & Garay, S. M.) 323-344 (Lippincott Williams & Wilkins, Philadelphia, 2004).
    • (2004) Tuberculosis , pp. 323-344
    • Jagirdar, J.1    Zagzag, D.2
  • 3
    • 34547135230 scopus 로고
    • (eds Kubica, G. P. & Wayne, L. G.) (Marcel Dekker, New York)
    • Bates, J. H. in The Mycobacteria: A Sourcebook (eds Kubica, G. P. & Wayne, L. G.) 991-1005 (Marcel Dekker, New York, 1984).
    • (1984) The Mycobacteria: A Sourcebook , pp. 991-1005
    • Bates, J.H.1
  • 4
    • 11144332364 scopus 로고    scopus 로고
    • (eds Rom, W. N. & Garay, S. M.) (Lippincott William & Wilkins, Philadelphia)
    • Daley, C. L. in Tuberculosis (eds Rom, W. N. & Garay, S. M.) 85-99 (Lippincott William & Wilkins, Philadelphia, 2004).
    • (2004) Tuberculosis , pp. 85-99
    • Daley, C.L.1
  • 5
    • 0004260595 scopus 로고    scopus 로고
    • (eds Rom, W. N. & Garay, S. M.) (Lippincott Williams & Wilkins, Philadelphia)
    • Condos, R. & Rom, W. N. in Tuberculosis (eds Rom, W. N. & Garay, S. M.) 285-299 (Lippincott Williams & Wilkins, Philadelphia, 2004).
    • (2004) Tuberculosis , pp. 285-299
    • Condos, R.1    Rom, W.N.2
  • 6
    • 77049229538 scopus 로고
    • The treated pulmonary lesion and its tubercle bacillus. II. The death and resurrection
    • Vandiviere, H. M., Loring, W. E., Melvin, I. & Willis, S. The treated pulmonary lesion and its tubercle bacillus. II. The death and resurrection. Am. J. Med. Sci. 232, 30-37 (1956).
    • (1956) Am. J. Med. Sci. , vol.232 , pp. 30-37
    • Vandiviere, H.M.1    Loring, W.E.2    Melvin, I.3    Willis, S.4
  • 7
    • 11144351597 scopus 로고
    • The treated pulmonary lesion and its tubercle bacillus. III. Drug susceptibility studies
    • Kennedy, H. E., Vandiviere, H. M., Melvin, I. G. & Willis, H. S. The treated pulmonary lesion and its tubercle bacillus. III. Drug susceptibility studies. Am. J. Med. Sci. 233, 676-684 (1957).
    • (1957) Am. J. Med. Sci. , vol.233 , pp. 676-684
    • Kennedy, H.E.1    Vandiviere, H.M.2    Melvin, I.G.3    Willis, H.S.4
  • 8
    • 11144294001 scopus 로고
    • The effects of extended incubation on propagability of tubercle bacilli
    • Kennedy, H. E., Vandiviere, H. M. & Willis, H. S. The effects of extended incubation on propagability of tubercle bacilli. Am. Rev. Tuberc. 77, 802-814 (1958).
    • (1958) Am. Rev. Tuberc. , vol.77 , pp. 802-814
    • Kennedy, H.E.1    Vandiviere, H.M.2    Willis, H.S.3
  • 9
    • 10744233688 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis growth at the cavity surface: A microenvironment with failed immunity
    • Kaplan, G. et al. Mycobacterium tuberculosis growth at the cavity surface: a microenvironment with failed immunity. Infect. Immun. 71, 7099-7108 (2003).
    • (2003) Infect. Immun. , vol.71 , pp. 7099-7108
    • Kaplan, G.1
  • 10
    • 0034982305 scopus 로고    scopus 로고
    • Pathogenesis of pulmonary Mycobacterium bovis infection: Basic principles established by the rabbit model
    • Dannenberg, A. M. Pathogenesis of pulmonary Mycobacterium bovis infection: basic principles established by the rabbit model. Tuberculosis (Edinb.) 81, 87-96 (2001).
    • (2001) Tuberculosis (Edinb.) , vol.81 , pp. 87-96
    • Dannenberg, A.M.1
  • 11
    • 0013816145 scopus 로고
    • Present aspects of bacterial resistance in tuberculosis
    • Canetti, G. Present aspects of bacterial resistance in tuberculosis. Am. Rev. Respir. Dis. 92, 687-703 (1965).
    • (1965) Am. Rev. Respir. Dis. , vol.92 , pp. 687-703
    • Canetti, G.1
  • 12
    • 0142074318 scopus 로고    scopus 로고
    • Stability of DNA patterns and evidence of Mycobacterium tuberculosis reactivation occurring decades after the initial infection
    • Lillebaek, T. et al. Stability of DNA patterns and evidence of Mycobacterium tuberculosis reactivation occurring decades after the initial infection. J. Infect. Dis. 188, 1032-1039 (2003).
    • (2003) J. Infect. Dis. , vol.188 , pp. 1032-1039
    • Lillebaek, T.1
  • 13
    • 0004260595 scopus 로고    scopus 로고
    • (eds Rom, W. N. & Garay, S. M.) (Lippincott Williams & Wilkins, Philadelphia)
    • Garay S. M. in Tuberculosis (eds Rom, W. N. & Garay, S. M.) 345-394 (Lippincott Williams & Wilkins, Philadelphia, 2004).
    • (2004) Tuberculosis , pp. 345-394
    • Garay, S.M.1
  • 14
    • 0141669013 scopus 로고    scopus 로고
    • Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infection
    • Capuano S. V. et al. Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infection. Infect Immun. 71, 5831-5844 (2003).
    • (2003) Infect. Immun. , vol.71 , pp. 5831-5844
    • Capuano, S.V.1
  • 16
    • 0028936417 scopus 로고
    • Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis
    • Chan, J., Tanaka, K., Carroll, D., Flynn, J. & Boom, B. R. Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis. Infect. Immun. 63, 736-740 (1995).
    • (1995) Infect. Immun. , vol.63 , pp. 736-740
    • Chan, J.1    Tanaka, K.2    Carroll, D.3    Flynn, J.4    Boom, B.R.5
  • 17
    • 0031010661 scopus 로고    scopus 로고
    • Identification of nitric oxide synthase as a protective locus against tuberculosis
    • MacMicking, J. D. et al. Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc. Natl Acad. Sci. USA 94, 5243-5248 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5243-5248
    • MacMicking, J.D.1
  • 18
    • 0032519735 scopus 로고    scopus 로고
    • Effects of aminoguanidine on latent murine tuberculosis
    • Flynn, J. L., Scanga, C. A., Tanaka, K. E. & Chan, J. Effects of aminoguanidine on latent murine tuberculosis. J. Immunol. 160 1796-1803 (1998).
    • (1998) J. Immunol. , vol.160 , pp. 1796-1803
    • Flynn, J.L.1    Scanga, C.A.2    Tanaka, K.E.3    Chan, J.4
  • 19
    • 0032794697 scopus 로고    scopus 로고
    • Reactivation of latent tuberculosis: Variations on the Cornell murine model
    • Scanga, C. A. et al. l] Reactivation of latent tuberculosis: variations on the Cornell murine model. Infect. Immun. 67, 4531-4538 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 4531-4538
    • Scanga, C.A.1
  • 20
    • 84960961533 scopus 로고
    • The fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. II. The conversion of tuberculous infection to the latent state by the administration of pyrazinamide and a companion drug
    • McCune, R. M., McDermott, W. & Tompsett, R. The fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. II. The conversion of tuberculous infection to the latent state by the administration of pyrazinamide and a companion drug. J. Exp. Med. 104, 763-802 (1956).
    • (1956) J. Exp. Med. , vol.104 , pp. 763-802
    • McCune, R.M.1    McDermott, W.2    Tompsett, R.3
  • 21
    • 0000164959 scopus 로고
    • Fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. I. The persistence of drug-susceptible tubercle bacilli in the tissues despite prolonged antimicrobial therapy
    • McCune, R. M. & Tompsett, R. Fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. I. The persistence of drug-susceptible tubercle bacilli in the tissues despite prolonged antimicrobial therapy. J. Exp. Med. 104, 737-762 (1956).
    • (1956) J. Exp. Med. , vol.104 , pp. 737-762
    • McCune, R.M.1    Tompsett, R.2
  • 22
    • 0029560476 scopus 로고
    • The bacterial DNA content of mouse organs in the Cornell model of dormant tuberculosis
    • de Wit, D., Wootton, M., Dhillon, J. & Mitchison, D. A. The bacterial DNA content of mouse organs in the Cornell model of dormant tuberculosis. Tuber. Lung Dis. 76, 555-562 (1995).
    • (1995) Tuber. Lung Dis. , vol.76 , pp. 555-562
    • de Wit, D.1    Wootton, M.2    Dhillon, J.3    Mitchison, D.A.4
  • 23
    • 0037596510 scopus 로고    scopus 로고
    • The complete genome sequence of Mycobacterium bovis
    • Garnier, T. et al. The complete genome sequence of Mycobacterium bovis. Proc. Natl Acad. Sci. USA 100, 7877-7882 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7877-7882
    • Garnier, T.1
  • 24
    • 0345714720 scopus 로고    scopus 로고
    • In situ study of abundant expression of proinflammatory chemokines and cytokines in pulmonary granulomas that develop in cynomolgus macaques experimentally infected with Mycobacterium tuberculosis
    • Fuller, C. L., Flynn, J. L. & Reinhart, T. A. In situ study of abundant expression of proinflammatory chemokines and cytokines in pulmonary granulomas that develop in cynomolgus macaques experimentally infected with Mycobacterium tuberculosis. Infect. Immun. 71, 7023-7034 (2003).
    • (2003) Infect. Immun. , vol.71 , pp. 7023-7034
    • Fuller, C.L.1    Flynn, J.L.2    Reinhart, T.A.3
  • 25
    • 0029944117 scopus 로고    scopus 로고
    • The Philippine cynomolgus monkey (Macaca fasicularis) provides a new nonhuman primate model of tuberculosis that resembles human disease
    • Walsh, G. P. et al. The Philippine cynomolgus monkey (Macaca fasicularis) provides a new nonhuman primate model of tuberculosis that resembles human disease. Nature Med. 2, 430-436 (1996).
    • (1996) Nature Med. , vol.2 , pp. 430-436
    • Walsh, G.P.1
  • 26
    • 0035949685 scopus 로고    scopus 로고
    • Divergent effect of bacillus Calmette-Guérin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: Implications for primate models in tuberculosis vaccine research
    • Langermans, J. A. et al. Divergent effect of bacillus Calmette-Guérin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: implications for primate models in tuberculosis vaccine research. Proc. Natl Acad. Sci. USA 98, 11497-11502 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 11497-11502
    • Langermans, J.A.1
  • 27
    • 0029976980 scopus 로고    scopus 로고
    • An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence
    • Wayne, L. G. & Hayes, L. G. An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence. Infect. Immun. 64, 2062-2069 (1996).
    • (1996) Infect. Immun. , vol.64 , pp. 2062-2069
    • Wayne, L.G.1    Hayes, L.G.2
  • 28
    • 0034780485 scopus 로고    scopus 로고
    • Nonreplicating persistence of Mycobacterium tuberculosis
    • Wayne, L. G. & Sohaskey C. D. Nonreplicating persistence of Mycobacterium tuberculosis. Annu. Rev. Microbiol. 55, 139-163 (2001).
    • (2001) Annu. Rev. Microbiol. , vol.55 , pp. 139-163
    • Wayne, L.G.1    Sohaskey, C.D.2
  • 29
    • 0032453525 scopus 로고    scopus 로고
    • Nitrate reduction as a marker for hypoxic shiftdown of Mycobacterium tuberculosis
    • Wayne, L. G. & Hayes, L. G. Nitrate reduction as a marker for hypoxic shiftdown of Mycobacterium tuberculosis. Tuber. Lung Dis. 79, 127-132 (1998).
    • (1998) Tuber. Lung Dis. , vol.79 , pp. 127-132
    • Wayne, L.G.1    Hayes, L.G.2
  • 31
    • 0344666693 scopus 로고    scopus 로고
    • Role of narK2X and narGHJI in hypoxic upregulation of nitrate reduction by Mycobacterim tuberculosis
    • Sohaskey, C. D. & Wayne, L. G. Role of narK2X and narGHJI in hypoxic upregulation of nitrate reduction by Mycobacterim tuberculosis. J. Bacteriol. 185, 7247-7256 (2003).
    • (2003) J. Bacteriol. , vol.185 , pp. 7247-7256
    • Sohaskey, C.D.1    Wayne, L.G.2
  • 32
    • 4544312369 scopus 로고    scopus 로고
    • The transcriptional responses of M. tuberculosis to inhibitors of metabolism: Novel insights into drug mechanisms of action
    • Boshoff, H. I. et al. The transcriptional responses of M. tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action. J. Biol. Chem. 279, 40174-40184 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 40174-40184
    • Boshoff, H.I.1
  • 33
    • 0035912791 scopus 로고    scopus 로고
    • Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding α-crystallin
    • Sherman, D. R. et al. Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding α-crystallin. Proc. Natl Acad. Sci. USA 98, 7534-7539 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7534-7539
    • Sherman, D.R.1
  • 34
    • 0242381240 scopus 로고    scopus 로고
    • Ribonucleotide reduction in Mycobacterium tuberculosis: Function and expression of genes encoding class Ib and class II ribonucleotide reductases
    • Dawes, S. S. et al. Ribonucleotide reduction in Mycobacterium tuberculosis: function and expression of genes encoding class Ib and class II ribonucleotide reductases. Infect. Immun. 71, 6124-6131 (2003).
    • (2003) Infect. Immun. , vol.71 , pp. 6124-6131
    • Dawes, S.S.1
  • 35
    • 0037306281 scopus 로고    scopus 로고
    • DNA alkylation damage as a sensor of nitrosative stress in Mycobacterium tuberculosis
    • Durbach, S. I. et al. DNA alkylation damage as a sensor of nitrosative stress in Mycobacterium tuberculosis. Infect Immun. 71, 997-1000 (2003).
    • (2003) Infect. Immun. , vol.71 , pp. 997-1000
    • Durbach, S.I.1
  • 36
    • 0037453719 scopus 로고    scopus 로고
    • DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis
    • Boshoff, H. I., Reed, M. B., Barry, C. E., 3rd & Mizrahi, V. DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis. Cell 113, 183-193 (2003).
    • (2003) Cell , vol.113 , pp. 183-193
    • Boshoff, H.I.1    Reed, M.B.2    Barry III, C.E.3    Mizrahi, V.4
  • 37
    • 11144356962 scopus 로고    scopus 로고
    • Functional and evolutionary genomics of Mycobacterium tuberculosis: Insights from genomic deletions in 100 strains
    • Tsolaki , A. G. et al. Functional and evolutionary genomics of Mycobacterium tuberculosis: insights from genomic deletions in 100 strains. Proc. Natl Acad. Sci. USA 101, 4865-4870 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 4865-4870
    • Tsolaki, A.G.1
  • 38
    • 1842788227 scopus 로고    scopus 로고
    • Stable association between strains of Mycobacterium tuberculosis and their human host populations
    • Hirsh, A. E., Tsolaki, A. G., DeRiemer, K., Feldman, M. W. & Small, P. M. Stable association between strains of Mycobacterium tuberculosis and their human host populations. Proc. Natl Acad. Sci. USA 101, 4871-4876 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 4871-4876
    • Hirsh, A.E.1    Tsolaki, A.G.2    DeRiemer, K.3    Feldman, M.W.4    Small, P.M.5
  • 39
    • 3242750587 scopus 로고    scopus 로고
    • Induction of a novel class of diacylglycerol acyltransferases and triacylglycerol accumulation in Mycobacterium tuberculosis as it goes into a dormancy-like state in culture
    • Daniel, J. et al. Induction of a novel class of diacylglycerol acyltransferases and triacylglycerol accumulation in Mycobacterium tuberculosis as it goes into a dormancy-like state in culture. J. Bacteriol. 186, 5017-5030 (2004).
    • (2004) J. Bacteriol. , vol.186 , pp. 5017-5030
    • Daniel, J.1
  • 40
    • 0036270739 scopus 로고    scopus 로고
    • Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling
    • Betts, J. C., Lukey, P. T., Robb, L. C., McAdam, R. A. & Duncan, K. Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling. Mol. Microbiol. 43, 717-731 (2002).
    • (2002) Mol. Microbiol. , vol.43 , pp. 717-731
    • Betts, J.C.1    Lukey, P.T.2    Robb, L.C.3    McAdam, R.A.4    Duncan, K.5
  • 41
    • 0043192889 scopus 로고    scopus 로고
    • The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice
    • Dahl, J. L. et al. The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice. Proc. Natl Acad. Sci. USA 100, 10026-10031 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 10026-10031
    • Dahl, J.L.1
  • 42
    • 3042790827 scopus 로고    scopus 로고
    • Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: A model for persistent organisms?
    • Hampshire, T. et al. Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: a model for persistent organisms? Tuberculosis (Edinb) 84, 228-238 (2004).
    • (2004) Tuberculosis (Edinb.) , vol.84 , pp. 228-238
    • Hampshire, T.1
  • 43
    • 3042838120 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis gene expression during adaptation to stationary phase and low-oxygen dormancy
    • Voskuil, M. I., Visconti, K. C. & Schoolnik, G. K. Mycobacterium tuberculosis gene expression during adaptation to stationary phase and low-oxygen dormancy. Tuberculosis (Edinb) 84, 218-227 (2004).
    • (2004) Tuberculosis (Edinb.) , vol.84 , pp. 218-227
    • Voskuil, M.I.1    Visconti, K.C.2    Schoolnik, G.K.3
  • 44
    • 0032836258 scopus 로고    scopus 로고
    • Inorganic polyphosphate: A molecule of many functions
    • Kornberg, A., Rao, N. N. & Ault-Riche, D. Inorganic polyphosphate: a molecule of many functions. Annu. Rev. Biochem. 68, 89-125 (1999).
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 89-125
    • Kornberg, A.1    Rao, N.N.2    Ault-Riche, D.3
  • 45
    • 0037311481 scopus 로고    scopus 로고
    • Sterilizing activities of fluoroquinolones against rifampin-tolerant populations of Mycobacterium tuberculosis
    • Hu, Y., Coates, A. R. & Mitchison, D. A. Sterilizing activities of fluoroquinolones against rifampin-tolerant populations of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 47, 653-657 (2003).
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 653-657
    • Hu, Y.1    Coates, A.R.2    Mitchison, D.A.3
  • 46
    • 0033764350 scopus 로고    scopus 로고
    • Detection of mRNA transcripts and active transcription in persistent Mycobacterium tuberculosis induced by exposure to rifampin or pyrazinamide
    • Hu, Y. et al. Detection of mRNA transcripts and active transcription in persistent Mycobacterium tuberculosis induced by exposure to rifampin or pyrazinamide. J. Bacteriol. 182, 6358-6365 (2000).
    • (2000) J. Bacteriol. , vol.182 , pp. 6358-6365
    • Hu, Y.1
  • 47
    • 2442685844 scopus 로고    scopus 로고
    • The search for new sterilizing antituberculosis drugs
    • Mitchison, D. A. The search for new sterilizing antituberculosis drugs. Front. Biosci. 9, 1059-1072 (2004).
    • (2004) Front. Biosci. , vol.9 , pp. 1059-1072
    • Mitchison, D.A.1
  • 48
    • 0034114442 scopus 로고    scopus 로고
    • Attenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosis
    • Hondalus, M. K. et al. Attenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosis. Infect. Immun. 68, 2888-2898 (2000).
    • (2000) Infect. Immun. , vol.68 , pp. 2888-2898
    • Hondalus, M.K.1
  • 49
    • 0035145539 scopus 로고    scopus 로고
    • Characterization of auxotrophic mutants of Mycobacterium tuberculosis and their potential as vaccine candidates
    • Smith, D. A., Parish, T., Stoker, N. G. & Bancroft, G. J. Characterization of auxotrophic mutants of Mycobacterium tuberculosis and their potential as vaccine candidates. Infect. Immun. 69 1142-1150 (2001).
    • (2001) Infect. Immun. , vol.69 , pp. 1142-1150
    • Smith, D.A.1    Parish, T.2    Stoker, N.G.3    Bancroft, G.J.4
  • 50
    • 0037634042 scopus 로고    scopus 로고
    • Vaccine efficacy of a lysine auxotroph of Mycobacterium tuberculosis
    • Pavelka, M. S., Chen, B., Kelley, C. L., Collins, F. M. & Jacobs W. R. Vaccine efficacy of a lysine auxotroph of Mycobacterium tuberculosis. Infect. Immun. 71, 4190-4192 (2003).
    • (2003) Infect. Immun. , vol.71 , pp. 4190-4192
    • Pavelka, M.S.1    Chen, B.2    Kelley, C.L.3    Collins, F.M.4    Jacobs, W.R.5
  • 51
    • 0032982779 scopus 로고    scopus 로고
    • Persistence and protective efficacy of a Mycobacterium tuberculosis auxotroph vaccine
    • Jackson, M. et al. Persistence and protective efficacy of a Mycobacterium tuberculosis auxotroph vaccine. Infect. Immun. 67, 2867-2873 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 2867-2873
    • Jackson, M.1
  • 52
    • 0036796061 scopus 로고    scopus 로고
    • A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis
    • Sambandamurthy, V. K. et al. A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis. Nature Med. 8, 1171-1174 (2002).
    • (2002) Nature Med. , vol.8 , pp. 1171-1174
    • Sambandamurthy, V.K.1
  • 53
    • 0033973479 scopus 로고    scopus 로고
    • The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential A growth in macrophages
    • De Voss, J. J. et al. The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential A growth in macrophages. Proc. Natl Acad. Sci. USA 97, 1252-1257 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1252-1257
    • De Voss, J.J.1
  • 54
    • 0342794213 scopus 로고    scopus 로고
    • Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
    • McKinney, J. D. et al. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase. Nature 406, 735-738 (2000).
    • (2000) Nature , vol.406 , pp. 735-738
    • McKinney, J.D.1
  • 55
    • 0348017149 scopus 로고    scopus 로고
    • The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide
    • Darwin, K. H., Ehrt, S., Gutierrez-Ramos, J. C., Weich, N. & Nathan, C. F. The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide. Science 302, 1963-1966 (2003).
    • (2003) Science , vol.302 , pp. 1963-1966
    • Darwin, K.H.1    Ehrt, S.2    Gutierrez-Ramos, J.C.3    Weich, N.4    Nathan, C.F.5
  • 56
    • 0042140672 scopus 로고    scopus 로고
    • Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program
    • Voskuil, M. I. et al. Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program. J. Exp. Med. 198, 705-713 (2003).
    • (2003) J. Exp. Med. , vol.198 , pp. 705-713
    • Voskuil, M.I.1
  • 57
    • 0034255209 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens
    • Nathan, C. & Shiloh, M. U. Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. Proc. Natl Acad. Sci. USA 97, 8841-8848 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8841-8848
    • Nathan, C.1    Shiloh, M.U.2
  • 58
    • 2542475060 scopus 로고    scopus 로고
    • Two sensor kinases contribute to the hypoxic response of Mycobacterium tuberculosis
    • Roberts, D. M., Liao, R. P., Wisedchaisri, G., Hol, W. G. & Sherman, D. R. Two sensor kinases contribute to the hypoxic response of Mycobacterium tuberculosis. J. Biol. Chem. 279, 23082-23087 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 23082-23087
    • Roberts, D.M.1    Liao, R.P.2    Wisedchaisri, G.3    Hol, W.G.4    Sherman, D.R.5
  • 59
    • 0043142536 scopus 로고    scopus 로고
    • Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment
    • Schnappinger, D. et al. Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment. J. Exp. Med. 198, 693-704 (2003).
    • (2003) J. Exp. Med. , vol.198 , pp. 693-704
    • Schnappinger, D.1
  • 60
    • 0035205354 scopus 로고    scopus 로고
    • Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis
    • Kana, B. D. et al. Characterization of the cydAB encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 183, 7076-7086 (2001).
    • (2001) J. Bacteriol. , vol.183 , pp. 7076-7086
    • Kana, B.D.1
  • 61
    • 0033928977 scopus 로고    scopus 로고
    • Redundancy of aerobic respiratory chains in bacteria? Routes, reasons and regulation
    • Poole, R. K. & Cook, G. M. Redundancy of aerobic respiratory chains in bacteria? Routes, reasons and regulation. Adv. Microb. Physiol. 43, 165-224 (2000).
    • (2000) Adv. Microb. Physiol. , vol.43 , pp. 165-224
    • Poole, R.K.1    Cook, G.M.2
  • 62
    • 0028024035 scopus 로고
    • Metronidazole is bactericidal to dormant cells of Mycobacterium tuberculosis
    • Wayne, L. G. & Sramek, H. A. Metronidazole is bactericidal to dormant cells of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 38, 2054-2058 (1994).
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 2054-2058
    • Wayne, L.G.1    Sramek, H.A.2
  • 63
  • 65
    • 0024759118 scopus 로고
    • Role of metronidazole in improving response and specific drug sensitivity in advanced pulmonary tuberculosis
    • Desai, C. R. et al. Role of metronidazole in improving response and specific drug sensitivity in advanced pulmonary tuberculosis. J. Assoc. Physicians India 37, 694-697 (1989 ).
    • (1989) J. Assoc. Physicians India , vol.37 , pp. 694-697
    • Desai, C.R.1
  • 66
    • 0036951936 scopus 로고    scopus 로고
    • Mycobacterium bovis BCG response regulator essential for hypoxic dormancy
    • Boon, C. & Dick, T. Mycobacterium bovis BCG response regulator essential for hypoxic dormancy. J. Bacteriol. 184, 6760-6767 (2002).
    • (2002) J. Bacteriol. , vol.184 , pp. 6760-6767
    • Boon, C.1    Dick, T.2
  • 67
    • 0037371176 scopus 로고    scopus 로고
    • Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis
    • Parish, T. et al. Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis. Infect. Immun. 71, 1134-1140 (2003).
    • (2003) Infect. Immun. , vol.71 , pp. 1134-1140
    • Parish, T.1
  • 68
    • 10744233580 scopus 로고    scopus 로고
    • Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis
    • Malhotra, V. et al. Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis. FEMS Microbiol. Lett. 231, 237-245 (2004).
    • (2004) FEMS Microbiol. Lett. , vol.231 , pp. 237-245
    • Malhotra, V.1
  • 69
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • Brown, J. M. & Wilson, W. R. Exploiting tumour hypoxia in cancer treatment. Nature Rev. Cancer 4, 437-447 (2004).
    • (2004) Nature Rev. Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 70
    • 0036839650 scopus 로고    scopus 로고
    • In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions
    • Fenhalls, G. et al. In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions. Infect. Immun. 70, 6330-6338 (2002).
    • (2002) Infect. Immun. , vol.70 , pp. 6330-6338
    • Fenhalls, G.1
  • 71
    • 0033872759 scopus 로고    scopus 로고
    • The stringent response of Mycobacterium tuberculosis is required for long-term survival
    • Primm, T. P. et al. The stringent response of Mycobacterium tuberculosis is required for long-term survival. J. Bacteriol. 182, 4889-4898 (2000).
    • (2000) J. Bacteriol. , vol.182 , pp. 4889-4898
    • Primm, T.P.1
  • 72
    • 0036777063 scopus 로고    scopus 로고
    • Life and death in a macrophage: Role of the glyoxylate cycle in virulence
    • Lorenz, M. C. & Fink, G. R. Life and death in a macrophage: role of the glyoxylate cycle in virulence. Eukaryot. Cell 1 657-662 (2002).
    • (2002) Eukaryot. Cell , vol.1 , pp. 657-662
    • Lorenz, M.C.1    Fink, G.R.2
  • 73
    • 0038481035 scopus 로고    scopus 로고
    • Genes involved in β-oxidation, energy metabolism and glyoxylate cycle are induced by Candida albicans during macrophage infection
    • Prigneau, O. et al. Genes involved in β-oxidation, energy metabolism and glyoxylate cycle are induced by Candida albicans during macrophage infection. Yeast 20, 723-730 (2003).
    • (2003) Yeast , vol.20 , pp. 723-730
    • Prigneau, O.1
  • 74
    • 10744228285 scopus 로고    scopus 로고
    • Differential expression of iron-, carbon-, and oxygen-responsive mycobacterial genes in the lungs of chronically infected mice and tuberculosis patients
    • Timm, J. et al. Differential expression of iron-, carbon-, and oxygen-responsive mycobacterial genes in the lungs of chronically infected mice and tuberculosis patients. Proc. Natl Acad. Sci. USA 100, 14321-14326 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 14321-14326
    • Timm, J.1
  • 75
    • 0036139212 scopus 로고    scopus 로고
    • Dependence of Mycobacterium bovis BCG on anaerobic nitrate reductase for persistence is tissue specific
    • Fritz, C., Maass, S., Kreft, A. & Bange, F. C. Dependence of Mycobacterium bovis BCG on anaerobic nitrate reductase for persistence is tissue specific. Infect. Immun. 70, 286-291 (2002).
    • (2002) Infect. Immun. , vol.70 , pp. 286-291
    • Fritz, C.1    Maass, S.2    Kreft, A.3    Bange, F.C.4
  • 76
    • 0034012134 scopus 로고    scopus 로고
    • Anaerobic nitrate reductase (narGHJI) activity of Mycobacterium bovis BCG in vitro and its contribution to virulence in immunodeficient mice
    • Weber, I., Fritz, C., Ruttkowski, S., Kraft, A. & Bange, F. C. Anaerobic nitrate reductase (narGHJI) activity of Mycobacterium bovis BCG in vitro and its contribution to virulence in immunodeficient mice. Mol. Microbiol. 35, 1017-1025 (2000).
    • (2000) Mol. Microbiol. , vol.35 , pp. 1017-1025
    • Weber, I.1    Fritz, C.2    Ruttkowski, S.3    Kraft, A.4    Bange, F.C.5
  • 77
    • 0031727390 scopus 로고    scopus 로고
    • Anaerobic growth of a 'strict aerobe' (Bacillus subtilis)
    • Nakano, M. M. & Zuber, P. Anaerobic growth of a 'strict aerobe' (Bacillus subtilis). Annu. Rev. Microbiol. 52, 165-190 (1998).
    • (1998) Annu. Rev. Microbiol. , vol.52 , pp. 165-190
    • Nakano, M.M.1    Zuber, P.2
  • 78
    • 3042774208 scopus 로고    scopus 로고
    • Long-term anaerobic survival of the opportunistic pathogen Pseudomonas aeruginosa via pyruvate fermentation
    • Eschbach, M. et al. Long-term anaerobic survival of the opportunistic pathogen Pseudomonas aeruginosa via pyruvate fermentation. J. Bacteriol. 186, 4596-4604 (2004).
    • (2004) J. Bacteriol. , vol.186 , pp. 4596-4604
    • Eschbach, M.1
  • 80
    • 3042829009 scopus 로고    scopus 로고
    • The influence of reduced oxygen availability on pathogenicity and gene expression in Mycobacterium tuberculosis
    • Bacon, J. et al. The influence of reduced oxygen availability on pathogenicity and gene expression in Mycobacterium tuberculosis. Tuberculosis (Edinb) 84, 205-217 (2004).
    • (2004) Tuberculosis (Edinb.) , vol.84 , pp. 205-217
    • Bacon, J.1
  • 81
    • 0037898938 scopus 로고    scopus 로고
    • Pyruvate ferredoxin oxidoreductase and its radical intermediate
    • Ragsdale, S. W. Pyruvate ferredoxin oxidoreductase and its radical intermediate. Chem. Rev. 103, 2333-4236 (2003).
    • (2003) Chem. Rev. , vol.103 , pp. 2333-4236
    • Ragsdale, S.W.1
  • 82
    • 2142694242 scopus 로고    scopus 로고
    • Uptake of carbon monoxide and hydrogen at environmentally relevant concentrations by mycobacteria
    • King, G. M. Uptake of carbon monoxide and hydrogen at environmentally relevant concentrations by mycobacteria. Appl. Environ. Microbiol. 69, 7266-7272 (2003).
    • (2003) Appl. Environ. Microbiol. , vol.69 , pp. 7266-7272
    • King, G.M.1
  • 83
    • 0041350368 scopus 로고    scopus 로고
    • Purification and characterization of formate dehydrogenase from Ancylobacter aquaticus strain KNK607M, and cloning of the gene
    • Nanba, H., Takaoka, Y. & Hasegawa, J. Purification and characterization of formate dehydrogenase from Ancylobacter aquaticus strain KNK607M, and cloning of the gene. Biosci. Biotechnol. Biochem. 67, 720-728 (2003).
    • (2003) Biosci. Biotechnol. Biochem. , vol.67 , pp. 720-728
    • Nanba, H.1    Takaoka, Y.2    Hasegawa, J.3
  • 84
    • 0038349268 scopus 로고    scopus 로고
    • Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis
    • Park, H. D. et al. Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis. Mol. Microbiol. 48, 833-843 (2003).
    • (2003) Mol. Microbiol. , vol.48 , pp. 833-843
    • Park, H.D.1
  • 85
    • 0030614468 scopus 로고    scopus 로고
    • 420-dependent glucose-6-phosphate dehydrogenase in Mycobacterium and Nocardia species, but absence from Streptomyces and Corynebacterium species and methanogenic Archaea
    • 420-dependent glucose-6-phosphate dehydrogenase in Mycobacterium and Nocardia species, but absence from Streptomyces and Corynebacterium species and methanogenic Archaea. FEMS Microbiol. Lett. 146, 129-134 (1997).
    • (1997) FEMS Microbiol. Lett. , vol.146 , pp. 129-134
    • Purwantini, E.1    Gillis, T.P.2    Daniels, L.3
  • 86
    • 11144347500 scopus 로고    scopus 로고
    • The membrane-bound electron transport system of Methanosarcina species
    • Deppenmeier, U. The membrane-bound electron transport system of Methanosarcina species. J. Bioenerg. Biomembr. 36, 55-64 (2004).
    • (2004) J. Bioenerg. Biomembr. , vol.36 , pp. 55-64
    • Deppenmeier, U.1
  • 88
    • 0032508046 scopus 로고    scopus 로고
    • Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
    • Cole, S. T. et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393, 537-544 (1998).
    • (1998) Nature , vol.393 , pp. 537-544
    • Cole, S.T.1
  • 89
    • 0345701347 scopus 로고    scopus 로고
    • Genes required for mycobacterial growth defined by high-density mutagenesis
    • Sassetti, C. M., Boyd, D. H. & Rubin, E. J. Genes required for mycobacterial growth defined by high-density mutagenesis. Mol. Microbiol. 48, 77-84 (2003).
    • (2003) Mol. Microbiol. , vol.48 , pp. 77-84
    • Sassetti, C.M.1    Boyd, D.H.2    Rubin, E.J.3
  • 90
    • 0034702247 scopus 로고    scopus 로고
    • A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis
    • Stover, C. K. et al. A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis. Nature 405, 962-966 (2000).
    • (2000) Nature , vol.405 , pp. 962-966
    • Stover, C.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.