Pathogenesis of experimental tuberculosis in animal models

Current Topics in Microbiology and Immunology

Volumn 215, Issue , 1996, Pages 157-179

  Mcmurray, D N ^a   Collins, F M ^b   Dannenberg Jr , A M ^c   Smith, D W ^d  

^a TEXAS A AND M UNIVERSITY   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c The Johns Hopkins University   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL GROWTH; BACTERIAL VIRULENCE; EXPERIMENTAL INFECTION; GUINEA PIG; HOST RESISTANCE; HOST SUSCEPTIBILITY; IMMUNOPATHOGENESIS; IMMUNOREACTIVITY; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; RABBIT; REVIEW; TUBERCULOSIS;

ANIMALIA; BACTERIA (MICROORGANISMS); CAVIA PORCELLUS; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; ORYCTOLAGUS CUNICULUS; SUS SCROFA;

EID: 0029757764     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-80166-2_7     Document Type: Review

References (104)

1. Allison MJ, Zappasodi P, Lurie MB (1962) Host-parasite relationships in natively resistant and susceptible rabbits on quantitative inhalation of tubercle bacilli: their significance for the nature of genetic resistance. Am Rev Respir Dis 85: 553-569
2. Ando M, Dannenberg AM Jr, Sugimoto M, Tepper BS (1977) Histochemical studies relating the activation of macrophages to the intracellular destruction of tubercle bacilli Am J Pathol 86: 623-634
3. Balasubramanian V, Guo-zhi, W, Wiegeshaus E, Smith D (1992a) Virulence of Mycobacterium tuberculosis for guinea pigs a quantitative modification of the assay developed by Mitchison. Tubercle Lung Dis 73: 268-272
4. Balasubramanian V, Wiegeshaus E, Smith D (1992b) Growth characteristics of recent sputum isolates in guinea pigs infected by the respiratory route. Infect Immun 60: 4762-4767
5. Balasubramanian V, Wiegeshaus E, Smith D (1994) Pathogenesis of tuberculosis: pathway to apical localization. Tubercle Lung Dis 75: 168-178
6. Barclay WR, Anacker RL, Brehmer W, Lief W, Ribi E (1970) Aerosol-induced tuberculosis in subhuman primates and the course of disease after intravenous BCG-vaccination. Infect Immun 2: 574-582
7. Bartow RA, McMurray DN (1989) Vaccination with Mycobacterium bovis BCG affects the distribution of Fc receptor-bearing T lymphocytes in experimental pulmonary tuberculosis Infect Immun 57: 1374-1379
8. Bloom BR, Murray CJ (1992) Tuberculosis: commentary on a reemergent killer. Science 257 1055-1064
9. Bouza E, Diaz-Lopez MD, Moreno S, Bernaldo de Quiros JC, Vincente T, Berenguer J (1993) Mycobacterium tuberculosis bacteremia in patients with and without HIV infection Arch Intern Med 153 496-500
10. Buschman E, Apt AS, Nickonenko BV, Moroz AM, Averbakh MH, Skamene E (1988) Genetic aspects of innate resistance and acquired immunity in inbred mice. Springer Semin Immunopathol 10: 319-336
11. Cohen MK, Bartow RA, Mintzer CL, McMurray DN (1987) Effects of diet and genetics on Mycobacterium bovis BCG vaccine efficacy in inbred guinea pigs Infect Immun 55: 314-319
12. Collins FM (1984) Protection against mycobacterial disease by means of live vaccines tested in experimental animals In: Kubica GP, Wayne LG (eds). The mycobacteria a sourcebook Dekker, New York, pp 787-839
13. Collins FM (1991) Antituberculous immunity: new solutions to an old problem. Rev Infect Dis 13: 940-950
14. Collins FM (1993) Tuberculosis: the return of an old enemy. Crit Rev Microbiol 19: 1-16
15. Collins FM, Mackaness GB (1970) The relationship of delayed hypersensitivity to acquired antituberculous immunity. I. Tuberculin sensitivity and resistance to reinfection In BCG-vaccinated mice Cell Immunol 1: 253-265
16. Collins FM, Montalbine V (1975) Relative immunogenicity of streptomycin-resistant and sensitive strains of BCG. II. Effect of route of inoculation on growth and immunogenicity. Am Rev Respir Dis 111: 43-51
17. Collins FM, Smith MM (1969) A comparative study of the virulence of Mycobacterium tuberculosis measured in mice and guinea pigs Am Rev Respir Dis 100: 631-639
18. Collins FM, Stokes RW (1987) Mycobacterium aium-complex infections in normal and immunodeficient mice Tubercle 68: 127-136
19. Collins FM, Wayne LG, Montalbile V (1974) The effect of cultural conditions on the distribution of Mycobacterium tuberculosis in the spleens and lungs of specific pathogen-free mice. Am Rev Respir Dis 110: 147-156
20. Collins FM, Auclair L, Mackaness GB (1977) Mycobacterium bovis (BCG) infections of the lymph nodes of normal, immune and cortisone-treated guinea pigs. J Natl Cancer Inst 59: 1527-1535
21. Comstock GW (1988) Identification of an effective vaccine against tuberculosis Am Rev Respir Dis 138: 479-480
22. Dalton DK, Pitts-Meek S, Keshav S, Figari IS, Bradley A, Stewart TA (1993) Multiple defects of immune cell function in mice with disrupted IFN-γ genes. Science 259: 1739-1742
23. Dannenberg AM Jr (1968) Cellular hypersensitivity and cellular immunity in the pathogenesis of tuberculosis; specificity, systemic and local nature, and associated macrophage enzymes Bacteriol Rev 32: 85-102
24. Dannenberg AM Jr (1984) Pathogenesis of tuberculosis' native and acquired resistance in animals and humans In: Leive L, Schlessinger D (eds) Microbiology - 1984. American Society for Microbiology, Washington D C, PP 344-354
25. Dannenberg AM Jr (1989) Immune mechanisms in the pathogenesis of pulmonary tuberculosis. Rev Infect Dis 11 [Suppl 2]: S369-S378
26. Dannenberg AM Jr (1990) Controlling tuberculosis: the pathologist's point of view, Res Microbiol 141: 192-196
27. Dannenberg AM Jr (1993) Immunopathogenesis of pulmonary tuberculosis. Hosp Pract 28: 51-58
28. Dannenberg AM Jr (1994a) Rabbit model of tuberculosis. In: Bloom BR (ed) Tuberculosis: pathogenesis, protection and control. ASM, Washington D C, pp 149-156
29. Dannenberg AM Jr (1994b) Roles of cytotoxic delayed-typed hypersensitivity and macrophage-activating cell-mediated immunity in the pathogenesis of tuberculosis. Immunobiology 191: 461-473
30. Dannenberg AM Jr, Rook GAW (1994) Pathogenesis of pulmonary tuberculosis: an interplay of tissue-damaging and macrophage-activating immune responses-dual mechanisms that control bacillary multiplication. In: Bloom BR (ed) Tuberculosis: pathogenesis, protection and control. ASM, Washington D C, pp 459-483
31. Dannenberg AM Jr, Tomashefski JF Jr (1988) Pathogenesis of pulmonary tuberculosis In: Fishman AP (ed) Pulmonary diseases and disorders, 2nd edn: vol 3 McGraw-Hill, New York, pp 1821-1842
32. Dannenberg AM Jr, Meyer OT, Esterly JR, Kambara T (1968) The local nature of immunity in tuberculosis, illustrated histochemically in dermal BCG lesions. J Immunol 100: 931-941
33. Dubos RJ, Pierce CH (1956) Differential characteristics in vitro and in vivo of several substrains of BCG IV Immunizing effectiveness. Am Rev Tuberc 74: 699-717
34. Dubos RJ, Schaefer WB (1953) Antituberculous immunity induced in mice by vaccination with living cultures of attenuated tubercle bacilli. J Exp Med 97: 207-220
35. Ellner JJ, Hinman AR, Booley SW, Fischt MA, Sepkowitz KA, Goldberger MJ, Schinnick TM, Iseman MD, Jacobs WR (1993) Tuberculosis symposium: emerging problems and promise. J Infect Dis 168: 537-551
36. Fine PEM (1989) The BCG story: lessons from the past and implications for the future. Rev Infect Dis 57 [Suppl 2]. S353-359
37. Flynn JL, Goldstein MM, Tribold KJ, Koller B, Bloom BR (1992) Major histocompatibility complex class 1-restricted T cells are required for resistance Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA 89: 12013-12017
38. Flynn JL, Chan J, Triebold KJ, Dalton DK, Stewart TA, Bloom BR (1993) An essential role for IFN-γ in resistance to Mycobacterium tuberculosis J Exp Med 178: 2248-2253
39. Fogarty Center Workshop (1978) Summary, conclusions and recommendations from the international workshop on "research toward global control and prevention of tuberculosis with an emphasis on vaccine development". J Infect Dis 158: 248-253
40. Fok JS, Ho RS, Arora PK, Harding GE, Smith DW (1976) Host-parasite relationships in experimental airborne tuberculosis V Lack of hematogeneous dissemination of Mycobacterium tuberculosis to the lungs of animals vaccinated with bacille-Calmette-Guerin J Infect Dis 133: 137-144
41. Grange JM, Gibson J, Osborn TW, Collins CH, Yates MD (1983) What is BCG? Tubercle 64: 129-139
42. Gray DF (1961) The relative natural resistance of rats and mice to experimental pulmonary tuberculosis. J Hyg 59: 471-477
43. Grover AA, Kim HK, Wiegeshaus EH, Smith DW (1967) Host-parasite relationships in experimental airborne tuberculosis II Reproducible infection by means of an inoculum preserved at - 70C J Bacteriol 94: 832-835
44. Gussman RA (1984) Notes on the particle size ouput of Collison Nebulizers. Am Indust Hyg Assoc J 45: B8-B12
45. Harding GE, Smith DW (1977) Host-parasite relationships in experimental airbone tuberculosis. VI. Influence of vaccination with bacille-Calmette-Guerin on the onset and/or extent of hematogeneous dissemination of virulent Mycobacterium tuberculosis to the lungs. J Infect Dis 136: 439-443
46. Ho RS, Fok JS, Harding GE, Smith DW (1978) Host-parasite relationships in experimental airborne tuberculosis. VII. Fate of Mycobacterium tuberculosis in primary lung lesions and in primary lesion-free lung tissue infected as a result of bacillemia. J Infect Dis 138: 237-241
47. Jespersen A (1956) Studies on tuberculin sensitivity and immunity in guinea pigs induced by vaccination with varying doses of BCG vaccine. Acta Pathol Microbiol Scand 38: 203-209
48. +T lymphocytes in intracellular microbial infections. Immunol Today 9: 168-174
49. Koch R (1882) Aetiologie der Tuberculose. Berl Klin Wochenschr 19 221-230
50. +T-cells. Science 248: 1227-1230
51. Lagranderie M, Ravisse P, Marchal G, Gheorghiu M, Balasubramanian V, Wiegeshaus E, Smith DW (1993) BCG-induced protection in guinea pigs vaccinated and challenged via the respiratory route Tubercle Lung Dis 74: 38-46
52. Largrange PH, Miller TE, Mackaness GB (1976) Parameters conditioning the potentiating effect of BCG on the immune response. IN: Lamoureaux G, Turcotte R, Portelance V (eds) BCG in cancer immunotherapy Grune and Stratton, New York, pp 23-26
53. Long ER, Vorwald AJ, Donaldson L (1931) Early cellular reaction to tubercle bacilli: a comparison of this reaction in normal and tuberculous guinea pigs and in guinea pigs immunized with dead bacilli. Arch Pathol 12: 956-969
54. Lurie MB (1964) Resistance to tuberculosis: experimental stuides in native and acquired defensive mechanisms. Harvard University Press, Cambridge MA
55. Lurie MB, Dannenberg AM Jr (1965) Macrophage function in infectious disease with inbred rabbits Bacteriol Rev 29 466-476
56. Lurie MB, Abramson BS, Heppleston AG (1952a) On the response of geneticaliy resistant and susceptible rabbits to the quantitative inhalation of human type tubercle bacilli and the nature of resistance to tueberculosis. J Exp Med 95: 119-134
57. Lurie MB, Zappasodi P, Cardona-Lynch E, Dannenberg AM Jr (1952b) The response to the intracutaneous inoculation of BCG as an index of native resistance to tuberculosis J Immunol 68: 369-387
58. Lurie MB, Zappasodi P, Tickner C (1955) On the nature of genetic resistance of tuberculosis in the light of the host-parasite relationships in natively resistant and susceptible rabbits Am Rev Tuberc Pulm Dis 72: 297-329
59. Lynch CL, Pierce-Chase CH, Dubos RJ (1965) A genetic study of susceptibility to experimental tuberculosis in mice infected with mammalian tubercle bacilli J Exp Med 121: 1051-1070
60. Mainali ES, McMurray DN (submitted for publication) Adoptive transfer of resistance to pulmonary tuberculosis in guinea pigs is altered by protein deficiency
61. McMurrary DN (1994) Guinea pig model of tuberculosis In Bloom BR (ed) Tuberculosis pathogenesis, protection, and control. ASM, Washington DC, pp 135-147
62. McMurray DN, Bartow RA (1992) Immunosuppression and alternation of resistance to pulmonary tuberculosis in guinea pigs by protein undernutrition. J Nutr 122: 738-743
63. McMurray DN, Echeverry A (1978) Cell-mediated immunity in anergic patients with pulmonary tuberculosis. Am Rev Respir Dis 118: 827-834
64. McMurray DN, Carlomagno MA, Mintzer CL, Tetzlaff CL (1985) Mycobacterium bovis BCG vaccine fails to protect protein-deficient guinea pigs against respiratory challenge with virulent Mycobacterium tuberculosis. Infect Immun 50: 555-559
65. McMurray DN, Kimball MS, Tetzlaff CL, Mintzer CL (1986a) Effects of protein deprivation and BCG vaccination on alveolar macrophage function in pulmonary tuberculosis. Am Rev Respir Dis 133: 1081-1085
66. McMurray DN, Mintzer CL, Tetzlaff CL, Carlomagno MA (1986b) Influence of dietary protein on the protective effect of BCG in guinea pigs. Tubercle 67: 31-39
67. McMurray DN, Mintzer CL, Bartow RA, Parr RL (1989) Dietary protein deficiency and Mycobacterium bovis BCG affect interleukin 2 activity in experimental pulmonary tuberculosis. Infect Immun 57: 2606-2611
68. Middlebrook GM (1952) An apparatus for airborne infection of mice. Proc Soc Exp Biol Med 80: 105-110
69. Mitchison DA (1964) The virulence of tubercle bacilli from patients with pulmonary tuberculosis in India and other countries. Bull Int Union Against TB 35: 287-306
70. Muller I, Cobbold S, Waldmann H, Kaufmann SHE (1990) Impaired resistance to Mycobacterium tuberculosis infection after selective in vivo depletion of L3T4+ and Lyt-2+ T cells. Infec Immun 55: 2037-2041
71. Nickonenko BV, Apt AS, Moroz AM, Averbakh MM, Skamene E (1985) Genetic analysis of susceptibility of mice to H37Rv tuberculosis infection: sensitivity versus relative resistance. Prog Leukoc Biol 3: 291-296
72. North RJ (1973) Importance of thymus-derived lymphocytes in cell-mediated immunity to infection. Cell Immunol 7: 166-176
73. North RJ, Izzo AA (1993) Granuloma formation in severe combined immunodeficient (SCID) mice in response to progressive BCG infection. Am J Pathol 142: 1959-1966
74. Orme IM (1987) The kinetics of emergence and loss of mediator T lymphocytes in response to infection with M. tuberculosis. J Immunol 138: 293-298
75. Orme IM, Collins FM (1983) Protection against Mycobacterium tuberculosis infection by adoptive immunotherapy J Exp Med 158: 74-83
76. Orme IM, Collins FM (1994) Mouse model of tuberculosis. In: Bloom BR (ed) Tuberculosis: pathogenesis, protection and control. American Society for Microbiology, Washington DC, pp 113-134
77. Orme IM, Miller ES, Roberts AD, Furney SK, Griffin JP, Dobos KM, Chi D, Rivoire B, Brennan PJ (1992) T lymphocytes mediating protection and cellular cytolysis during the course of Mycobacterium tuberculosis infection. J Immunol 148: 189-196
78. Phalen SW, McMurray DN (1993a) T lymphocyte response in a guinea pig model of tuberculous pleuritis Infect Immun 61: 142-145
79. Phalen SW, McMurray DN (1993b) Production of tumor necrosis factor (TNFα) in experimental tuberculous pleuritis. J Immunol 150: 66A
80. Pierce CH, Dubos RJ and Schaefer WB (1956) Differential characteristics in vitro and in vivo of several substrains of BCG. III. Multiplication and survival in vivo Am Rev Tuberc 74: 683-698
81. Pittsfield Conference (1986) Supplement of future research in tuberculosis. Prospects and priorities for elimination (Pittsfield, MA) Am Rev Respir Dis 134: 401-423
82. Prabhakar R, Venkataraman P, Vallishayee RS, Resser P, Musa S, Hashim R, Kim Y, Dimmer C, Wiegeshaus E, Edwards M, Smith DW (1987) Virulence for guinea pigs of tubercle bacilli isolated from the sputum of persons included in the BCG trial, Chingleput district, south India. Tubercle 68: 3-17
83. Ratcliffe HL, Paliadino VS (1953) Tuberculosis induced by droplet nuclei infection: initial homogeneous response of small mammals (rats, mice, guinea pigs and hamsters) to human and to bovine bacilli and the rate and pattern of tubercle development. J Exp Med 97: 61-68
84. Riley RL, Mills CC, O'Grady F, Sultan LU, Wittstadt F, Shivpuri DN (1962) Infectiousness of air from a tuberculosis ward. Ultraviolet irradiation of infected air: comparative infectiousness of different patients Am Rev Respir Dis 85 511-525
85. Rook GAW (1990) Mycobacteria, cytokines and antibiotics. Pathol Biol 38: 276-280
86. Schaaf HS, Gie RP, Beyers N, Smuts N, Donald PR (1993) Tuberculosis in infants less than 3 months of age. Arch Dis Child 69: 371-374
87. Schultz LD, Sidman CL (1987) Genetically determined murine models of immunodeficiency. Annu Rev Immunol 5: 367-403
88. Siebenmann CO, Barbara C (1974) Quantitative evaluation of the effectiveness of Connaught freeze-dried BCG vaccine in mice and guinea pigs. Bull World Health Organ 51: 283-290
89. Smith DW, Harding GE (1977a) Animal model experimental airborne tuberculosis in the guinea pig. Am J Pathol 89: 273-276
90. Smith DW, Harding GE (1977b) Approaches to the validation of animal test systems for assay of the protective potency of BCG vaccines. J Biol Stand 5: 131-138
91. Smith DW, Wiegeshaus EH (1989) What animal models can teach us about the pathogenesis of tuberculosis in humans. Rev Infect Dis 11 S385-S393
92. Smith DW, McMurray DN, Wiegeshaus EH, Grover AA, Harding GE (1970) Host-parasite relationships in experimental airbrone tuberculosis IV. Early events in the course of infection in vaccinated and nonvaccinated guinea pigs. Am Rev Respir Dis 102: 937-949
93. Smith DW, Harding G, Chan J, Edwards M, Hank J, Muller D, Sobhi F (1979) Potency of 10 BCG vaccines as evaluated by their influence on the bacillemic phase of experimental airborne tuberculosis in guinea-pigs. J Biol Stand 7: 179-197
94. Smith DW, Balasubramanian V, Wiegeshaus E (1991) A guinea pig model of experimental airborne tuberculosis for evaluation of the response to chemotherapy: the effect on bacilli in the initial phase of treatment. Tubercle 72: 223-231
95. Stead WW (1989) Pathogenesis of tuberculosis: clinical and epidemiological perspective. Rev Infect Dis 11: 366-368
96. Tsuda T, Dannenberg AM, Jr Ando M, Abbey H, Corrin AR (1976) Mononuclear cell turn-over in chronic inflammation Studies on tritiated thymidine-labeled cells in the blood, tuberculin traps, and dermal BCG lesions of rabbits. Am J Pathol 83: 255-268
97. Wells AQ (1937) Tuberculosis in wild voles. Lancet 232 1221
98. Wessels CC (1941) Tuberculosis in the rat. I. Gross organ changes and tuberculin sensitivity in rats infected with tubercle bacilli. II. The fate of tubercle bacilli in the various organs of the rat III. The correlation between the histological changes and the fate of living tubercle bacilli in the organs of the albino rat. Am Rev Tuberc Pulm Dis 43: 449-458; 459-474; 637-644
99. Wiegeshaus EH, Smith DW (1989) Evaluation of the protective potency of new tuberculosis vaccines. Rev Infect Dis 11 [Suppl]: S484-S490
100. Wiegeshaus EH, McMurray DN, Grover AA, Harding GE, Smith DW (1970) Host-parasite relationships in experimental airborne tuberculosis III relevance of microbial enumeration to acquired cellular resistance in guinea pigs. Am Rev Respir Dis 102: 422-429
101. Wiegeshaus E, Harding G, McMurray D, Grover AA, Smith DW (1971) A cooperative evaluation of test systems used to assay tuberculosis vaccines. Bull World Health Organ 45: 543-550
102. Wiegeshaus EH, Balasubramanian V, Smith DW (1989) Immunity to tuberculosis from the perspective of pathogenesis Infect Immun 57: 3671-3676
103. World Health Organization (1976) The role of the individual and the community in the research, development, and used of biologicals with critieria for guidelines a memorandum Bull WHO 54: 645-655
104. World Health Organization (1982) Immunological research in tuberculosis a memorandum Bull. WHO 60: 723-727