메뉴 건너뛰기




Volumn 9, Issue , 2004, Pages 1059-1072

The search for new sterilizing anti-tuberculosis drugs

Author keywords

Bacterium; Disease; Infection; Lung; Micro aerophilie; Microorganisms; Persisters; Review; Sterilizing; TB; Therapeutics; Treatment; Tuberculosis

Indexed keywords

AMINOSALICYLIC ACID; CHEMOSTERILANT; ETHAMBUTOL; PYRAZINAMIDE; RIFAMPICIN; STREPTOMYCIN; TUBERCULOSTATIC AGENT;

EID: 2442685844     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/1293     Document Type: Review
Times cited : (90)

References (59)
  • 1
    • 0035038977 scopus 로고    scopus 로고
    • The need for new drugs against Tuberculosis - Obstacles, opportunities, and next steps
    • O'Brien R. & P.P. Nunn: The need for new drugs against Tuberculosis - obstacles, opportunities, and next steps. Am J Respir Crit Care Med 162, 1055-1058 (2001)
    • (2001) Am J Respir Crit Care Med , vol.162 , pp. 1055-1058
    • O'Brien, R.1    Nunn, P.P.2
  • 3
    • 0037417012 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis in the extracellular compartment: An underestimated adversary
    • Grosset J: Mycobacterium tuberculosis in the extracellular compartment: an underestimated adversary. Antimicrob Agents Chemother 47, 833-836 (2003)
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 833-836
    • Grosset, J.1
  • 4
    • 0027476452 scopus 로고
    • Quantitative bacillary response to treatment in HIV-associated pulmonary tuberculosis
    • Brindle R.J., P.P. Nunn, W. Githui, B.W. Allen, S. Gathua & P. Waiyaki: Quantitative bacillary response to treatment in HIV-associated pulmonary tuberculosis. Am Rev Respir Dis 147, 958-961 (1993)
    • (1993) Am Rev Respir Dis , vol.147 , pp. 958-961
    • Brindle, R.J.1    Nunn, P.P.2    Githui, W.3    Allen, B.W.4    Gathua, S.5    Waiyaki, P.6
  • 5
    • 0001837393 scopus 로고    scopus 로고
    • Serial counts of Mycobacterium tuberculosis in sputum as surrogate markers of the sterilising activity of rifampicin and pyrazinamide in treating pulmonary tuberculosis
    • Brindle R, J., Odhiambo & D. Mitchison: Serial counts of Mycobacterium tuberculosis in sputum as surrogate markers of the sterilising activity of rifampicin and pyrazinamide in treating pulmonary tuberculosis. BMC Pulmonary Medicine 1,2. (2001)
    • (2001) BMC Pulmonary Medicine , vol.1 , pp. 2
    • Brindle, R.1    Odhiambo, J.2    Mitchison, D.3
  • 6
  • 7
    • 0000322730 scopus 로고
    • The effect of low oxygen tension upon the development of experimental tuberculosis
    • Rich A.R., & R.H. Follis Jr: The effect of low oxygen tension upon the development of experimental tuberculosis. Bull Johns Hopkins Hospital 71, 345-357 (1942)
    • (1942) Bull Johns Hopkins Hospital , vol.71 , pp. 345-357
    • Rich, A.R.1    Follis Jr., R.H.2
  • 8
    • 0034811898 scopus 로고    scopus 로고
    • Resuscitation of dormant Mycobacterium tuberculosis by phospholipids or specific peptides
    • Zhang Y., Y Yang, A Woods, R.J. Cotter & Z. Sun: Resuscitation of dormant Mycobacterium tuberculosis by phospholipids or specific peptides. Biochem Biophys Res Commun 284, 542-547 (2001)
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 542-547
    • Zhang, Y.1    Yang, Y.2    Woods, A.3    Cotter, R.J.4    Sun, Z.5
  • 10
    • 0038628994 scopus 로고    scopus 로고
    • The bactericidal and sterilising activities of antituberculosis drugs during the first 14 days
    • Jindani A, CJ. Doré & D.A. Mitchison: The bactericidal and sterilising activities of antituberculosis drugs during the first 14 days. Am J Respir Crit Care Med 167, 1348-1354 (2003)
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1348-1354
    • Jindani, A.1    Doré, C.J.2    Mitchison, D.A.3
  • 11
    • 50349141358 scopus 로고
    • Treatment of staphylococcal infections with penicillin
    • Bigger J.W: Treatment of staphylococcal infections with penicillin. Lancet ii, 497-500 (1944)
    • (1944) Lancet , vol.2 , pp. 497-500
    • Bigger, J.W.1
  • 12
    • 0008759129 scopus 로고
    • The in vitro action of antituberculous agents against multiplying and non-multiplying microbial cells
    • Hobby G.L. & T.F Lenert: The in vitro action of antituberculous agents against multiplying and non-multiplying microbial cells. Am Rev Tuberc Pulm Dis 76, 1031-1048 (1957)
    • (1957) Am Rev Tuberc Pulm Dis , vol.76 , pp. 1031-1048
    • Hobby, G.L.1    Lenert, T.F.2
  • 13
    • 0019486287 scopus 로고
    • Experimental models to explain the high sterilizing activity of rifampin in the chemotherapy of tuberculosis
    • Dickinson J.M. & D.A. Mitchison: Experimental models to explain the high sterilizing activity of rifampin in the chemotherapy of tuberculosis. Amer Rev Resp Dis 123, 367-371 (1981)
    • (1981) Amer Rev Resp Dis , vol.123 , pp. 367-371
    • Dickinson, J.M.1    Mitchison, D.A.2
  • 14
    • 0029976980 scopus 로고    scopus 로고
    • An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence
    • Wayne L.G & L.G. Hayes: An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence. Infect Immun 64, 2062-2069 (1996)
    • (1996) Infect Immun , vol.64 , pp. 2062-2069
    • Wayne, L.G.1    Hayes, L.G.2
  • 15
    • 0033764350 scopus 로고    scopus 로고
    • Detection of mRNA transcripts and active transcription in persistent Mycobacterium tuberculosis induced by exposure to rifampin or pyrazinamide
    • Hu Y, J. A. Mangan, J. Dhillon, K.M. Sole, D.A. Mitchison, P.D. Butcher & A.R.M. Coates: Detection of mRNA transcripts and active transcription in persistent Mycobacterium tuberculosis induced by exposure to rifampin or pyrazinamide. J Bacteriol 182, 6358-6365 (2000)
    • (2000) J Bacteriol , vol.182 , pp. 6358-6365
    • Hu, Y.1    Mangan, J.A.2    Dhillon, J.3    Sole, K.M.4    Mitchison, D.A.5    Butcher, P.D.6    Coates, A.R.M.7
  • 16
    • 0035822573 scopus 로고    scopus 로고
    • Increased levels of sigJ mRNA in late stationary phase cultures of Mycobacterium tuberculosis detected by DNA array hybridisation
    • Hu Y. & A.R.M. Coates: Increased levels of sigJ mRNA in late stationary phase cultures of Mycobacterium tuberculosis detected by DNA array hybridisation. FEMS Microbiol Lett 202, 59-65 (2001)
    • (2001) FEMS Microbiol Lett , vol.202 , pp. 59-65
    • Hu, Y.1    Coates, A.R.M.2
  • 17
    • 0037311481 scopus 로고    scopus 로고
    • Sterilizing activities of fluoroquinolones against rifampin-tolerant populations of Mycobacterium tuberculosis
    • Hu Y, A.R.M. Coates & D.A. Mitchison: Sterilizing activities of fluoroquinolones against rifampin-tolerant populations of Mycobacterium tuberculosis. Antimicrob Agents Chemother 47, 653-657 (2003)
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 653-657
    • Hu, Y.1    Coates, A.R.M.2    Mitchison, D.A.3
  • 18
    • 0031656471 scopus 로고    scopus 로고
    • Metronidazole has no antibacterial effect in Cornell model murine tuberculosis
    • Dhillon J. B.W. Allen, Y-M Hu, A.R.M. Coates & D.A. Mitchison: Metronidazole has no antibacterial effect in Cornell model murine tuberculosis. Int J Tuberc Lung Dis 2, 736-742 (1998)
    • (1998) Int J Tuberc Lung Dis , vol.2 , pp. 736-742
    • Allen, D.J.B.W.1    Hu, Y.-M.2    Coates, A.R.M.3    Mitchison, D.A.4
  • 19
    • 84960961533 scopus 로고
    • The fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. II. The conversion of tuberculous infection to the latent state by the administration of pyrazinamide and a companion drug
    • McCune R, R. Tompsett & W. McDermott: The fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. II. The conversion of tuberculous infection to the latent state by the administration of pyrazinamide and a companion drug. J Exp Med 104, 763-803 (1956)
    • (1956) J Exp Med , vol.104 , pp. 763-803
    • McCune, R.1    Tompsett, R.2    McDermott, W.3
  • 20
    • 0032821532 scopus 로고    scopus 로고
    • Studies on the treatment of tuberculosis undertaken by the British Medical Research Council Tuberculosis Units, 1946-1984, with relevant subsequent publications
    • Fox W, G.A. Ellard & D A. Mitchison: Studies on the treatment of tuberculosis undertaken by the British Medical Research Council Tuberculosis Units, 1946-1984, with relevant subsequent publications. Int J Tuberc Lung Dis 3, S231-S279 (1999)
    • (1999) Int J Tuberc Lung Dis , vol.3
    • Fox, W.1    Ellard, G.A.2    Mitchison, D.A.3
  • 21
    • 0000652832 scopus 로고    scopus 로고
    • Genetics of Drug Resistance in Mycobacterium tuberculosis
    • Eds: Hatfull G F, Jacobs W R, ASM Press, Washington DC
    • Zhang Y & A. Telenti: Genetics of Drug Resistance in Mycobacterium tuberculosis. In: Molecular Genetics of Mycobacteria. Eds: Hatfull G F, Jacobs W R, ASM Press, Washington DC, 235-254 (2000)
    • (2000) Molecular Genetics of Mycobacteria , pp. 235-254
    • Zhang, Y.1    Telenti, A.2
  • 22
    • 0342637054 scopus 로고
    • The effect of isoniazid on growing and resting tubercle bacilli
    • Schaefer W.B: The effect of isoniazid on growing and resting tubercle bacilli. Amer Rev Tuberc 69, 125-127 (1954)
    • (1954) Amer Rev Tuberc , vol.69 , pp. 125-127
    • Schaefer, W.B.1
  • 23
    • 0037252098 scopus 로고    scopus 로고
    • The curious characteristics of pyrazinamide: A review
    • Zhang Y & D.A. Mitchison: The curious characteristics of pyrazinamide: a review. Int J Tuberc Lung Dis 7, 6-21 (2003)
    • (2003) Int J Tuberc Lung Dis , vol.7 , pp. 6-21
    • Zhang, Y.1    Mitchison, D.A.2
  • 24
    • 0001676804 scopus 로고
    • The bactericidal activities of antituberculous drugs
    • Mitchison D.A. & J.B. Selkon: The bactericidal activities of antituberculous drugs. Amer Rev Tuberc 74, 109-116 (1956)
    • (1956) Amer Rev Tuberc , vol.74 , pp. 109-116
    • Mitchison, D.A.1    Selkon, J.B.2
  • 25
    • 0009834157 scopus 로고
    • Comparative efficacy of three streptomycin and para-aminosalicylic acid regimens of prolonged duration in patients with previously untreated pulmonary tuberculosis
    • Tucker W.B: Comparative efficacy of three streptomycin and para-aminosalicylic acid regimens of prolonged duration in patients with previously untreated pulmonary tuberculosis. Am Rev Tuberc 72, 733-755 (1955)
    • (1955) Am Rev Tuberc , vol.72 , pp. 733-755
    • Tucker, W.B.1
  • 26
    • 0014257734 scopus 로고
    • Streptomycin plus thiacetazone (Thioacetazone) compared with streptomycin plus PAS and with isoniazid plus thiacetazone in the treatment of pulmonary tuberculosis in Rhodesia
    • Briggs I.L., W.R. Rochester & D.H. Shennan: Streptomycin plus thiacetazone (Thioacetazone) compared with streptomycin plus PAS and with isoniazid plus thiacetazone in the treatment of pulmonary tuberculosis in Rhodesia. Tubercle 49, 48-69 (1968)
    • (1968) Tubercle , vol.49 , pp. 48-69
    • Briggs, I.L.1    Rochester, W.R.2    Shennan, D.H.3
  • 27
    • 0003036659 scopus 로고
    • Implications of the phenomenon of open cavity healing for the chemotherapy of pulmonary tuberculosis
    • Russell W.F. Jr., S.H. Dressler, G. Middlebrook & J. Denst: Implications of the phenomenon of open cavity healing for the chemotherapy of pulmonary tuberculosis. Am Rev Tuberc PuIm Dis 71, 441-446 (1955)
    • (1955) Am Rev Tuberc PuIm Dis , vol.71 , pp. 441-446
    • Russell Jr., W.F.1    Dressler, S.H.2    Middlebrook, G.3    Denst, J.4
  • 28
    • 0033812380 scopus 로고    scopus 로고
    • Role of individual drugs in the chemotherapy of tuberculosis
    • Mitchison D.A: Role of individual drugs in the chemotherapy of tuberculosis. Int J Tuberc Lung Dis 4, 796-806. (2000)
    • (2000) Int J Tuberc Lung Dis , vol.4 , pp. 796-806
    • Mitchison, D.A.1
  • 29
    • 0014128753 scopus 로고
    • Activité antituberculeuse expérimentale de la rifampicine, dérivé de la rifamycine SV
    • Grumbach F. & N. Rist: Activité antituberculeuse expérimentale de la rifampicine, dérivé de la rifamycine SV. Rev Tuberc Pneumol 31, 749-762 (1967)
    • (1967) Rev Tuberc Pneumol , vol.31 , pp. 749-762
    • Grumbach, F.1    Rist, N.2
  • 30
    • 0018121731 scopus 로고
    • The sterilizing value of rifampicin and pyrazinamide in experimental short course chemotherapy
    • Grosset J: The sterilizing value of rifampicin and pyrazinamide in experimental short course chemotherapy. Tubercle 59, 287-297 (1978)
    • (1978) Tubercle , vol.59 , pp. 287-297
    • Grosset, J.1
  • 31
    • 84890265975 scopus 로고
    • Controlled clinical trial of short-course (6-month) regimens of chemotherapy for treatment of pulmonary tuberculosis
    • East African/British Medical Research Council: Controlled clinical trial of short-course (6-month) regimens of chemotherapy for treatment of pulmonary tuberculosis. Lancet May 20, 1079-1085 (1972)
    • (1972) Lancet , vol.MAY 20 , pp. 1079-1085
  • 32
    • 0017710095 scopus 로고
    • Controlled trial of 6-month and 9-month regimens of daily and intermittent streptomycin plus isoniazid plus pyrazinamide for pulmonary tuberculosis in Hong Kong. The results up to 30 months
    • Hong Kong Chest Service/British Medical Research Council: Controlled trial of 6-month and 9-month regimens of daily and intermittent streptomycin plus isoniazid plus pyrazinamide for pulmonary tuberculosis in Hong Kong. The results up to 30 months. Am Rev Respir Dis 115, 727-735 (1977)
    • (1977) Am Rev Respir Dis , vol.115 , pp. 727-735
  • 33
    • 84913812022 scopus 로고
    • Short course chemotherapy in pulmonary tuberculosis
    • British Thoracic Association: Short course chemotherapy in pulmonary tuberculosis. Lancet 1, 1182 (1980)
    • (1980) Lancet , vol.1 , pp. 1182
  • 34
    • 0022624710 scopus 로고
    • Long-term follow up of a clinical trial of six-month and four-month regimens of chemotherapy in the treatment of pulmonary tuberculosis
    • Singapore Tuberculosis Service/British Medical Research Council: Long-term follow up of a clinical trial of six-month and four-month regimens of chemotherapy in the treatment of pulmonary tuberculosis. Am Rev Respir Dis 133, 779-783 (1986)
    • (1986) Am Rev Respir Dis , vol.133 , pp. 779-783
  • 35
    • 0022006051 scopus 로고
    • Clinical trial of three 6-month regimens of chemotherapy given intermittently in the continuation phase in the treatment of pulmonary tuberculosis
    • Singapore Tuberculosis Service/British Medical Research Council: Clinical trial of three 6-month regimens of chemotherapy given intermittently in the continuation phase in the treatment of pulmonary tuberculosis. Am Rev Respir Dis 132, 374-378 (1985)
    • (1985) Am Rev Respir Dis , vol.132 , pp. 374-378
  • 36
    • 0025980585 scopus 로고
    • Assessment of a daily combined preparation of isoniazid, rifampin and pyrazinamide in a controlled trial of three 6-month regimens for smear-positive pulmonary tuberculosis
    • Singapore Tuberculosis Service/British Medical Research Council: Assessment of a daily combined preparation of isoniazid, rifampin and pyrazinamide in a controlled trial of three 6-month regimens for smear-positive pulmonary tuberculosis. Am Rev Respir Dis 143, 707-712 (1991)
    • (1991) Am Rev Respir Dis , vol.143 , pp. 707-712
  • 37
    • 0019955610 scopus 로고
    • A controlled trial of six months chemotherapy in pulmonary tuberculosis. Second Report: Results during the 24 months after the end of chemotherapy
    • British Thoracic Association: A controlled trial of six months chemotherapy in pulmonary tuberculosis. Second Report: Results during the 24 months after the end of chemotherapy. Am Rev Respir Dis 126, 460-462 (1982)
    • (1982) Am Rev Respir Dis , vol.126 , pp. 460-462
  • 38
    • 0019513328 scopus 로고
    • th study
    • th study. Am Rev Respir Dis 123, 165-170 (1981)
    • (1981) Am Rev Respir Dis , vol.123 , pp. 165-170
  • 39
    • 0026028244 scopus 로고
    • Controlled trial of 2, 4 and 6 months of pyrazinamide in 6-month, 3 x weekly regimens for smear-positive pulmonary tuberculosis, including an assessment of a combined preparation of isoniazid, rifampinand pyrazinamide
    • Hong Kong Chest Service/British Medical Research Council: Controlled trial of 2, 4 and 6 months of pyrazinamide in 6-month, 3 x weekly regimens for smear-positive pulmonary tuberculosis, including an assessment of a combined preparation of isoniazid, rifampinand pyrazinamide. Am Rev Respir Dis 143, 700-706 (1991)
    • (1991) Am Rev Respir Dis , vol.143 , pp. 700-706
  • 40
    • 0022607622 scopus 로고
    • Controlled clinical trial of 4 short-course regimens of chemotherapy (three 6-month and one 8-month) for pulmonary tuberculosis. Final report
    • East and Central African/British Medical Research Council (fifth Collaborative Study): Controlled clinical trial of 4 short-course regimens of chemotherapy (three 6-month and one 8-month) for pulmonary tuberculosis. Final report. Tubercle 67, 5-15 (1986)
    • (1986) Tubercle , vol.67 , pp. 5-15
  • 42
    • 0030009657 scopus 로고    scopus 로고
    • Early bactericidal activity of ethambutol, pyrazinamide and the fixed combination of isoniazid, rifampicin and pyrazinamide (Rifater) in patients with pulmonary tuberculosis
    • Botha F.J.H., F.A. Sirgel, D.P. Parkin, B.W. van de Wal, P.R. Donald & D.A. Mitchison: Early bactericidal activity of ethambutol, pyrazinamide and the fixed combination of isoniazid, rifampicin and pyrazinamide (Rifater) in patients with pulmonary tuberculosis. S Afr Med J, 86, 155-158 (1996)
    • (1996) S Afr Med J , vol.86 , pp. 155-158
    • Botha, F.J.H.1    Sirgel, F.A.2    Parkin, D.P.3    Van De Wal, B.W.4    Donald, P.R.5    Mitchison, D.A.6
  • 43
    • 0022335191 scopus 로고
    • The action of antituberculosis drugs in short-course chemotherapy
    • Mitchison D.A: The action of antituberculosis drugs in short-course chemotherapy. Tubercle 66, 219-225 (1985)
    • (1985) Tubercle , vol.66 , pp. 219-225
    • Mitchison, D.A.1
  • 44
    • 0025363229 scopus 로고
    • Pyrazinamide and pyrazinoic acid activity against tubercle bacilli in cultured human macrophages and in the BACTEC system
    • Salfinger M., A. J. Crowle & L.B. Reller: Pyrazinamide and pyrazinoic acid activity against tubercle bacilli in cultured human macrophages and in the BACTEC system. J Infect Dis 162, 201-207 (1990)
    • (1990) J Infect Dis , vol.162 , pp. 201-207
    • Salfinger, M.1    Crowle, A.J.2    Reller, L.B.3
  • 45
    • 0023930270 scopus 로고
    • Pyrazinamide is not effective against intracellularly growing Mycobacterium tuberculosis
    • Rastogi N., M.C. Potar & H.L. David: Pyrazinamide is not effective against intracellularly growing Mycobacterium tuberculosis. Antimicrob Agents Chemother 32, 287 (1988)
    • (1988) Antimicrob Agents Chemother , vol.32 , pp. 287
    • Rastogi, N.1    Potar, M.C.2    David, H.L.3
  • 46
    • 0034086436 scopus 로고    scopus 로고
    • Pyrazinamide is not active against Mycobacterium tuberculosis residing in cultured human monocyte-derived macrophages
    • Heifets L., M. Higgins & B. Simon: Pyrazinamide is not active against Mycobacterium tuberculosis residing in cultured human monocyte-derived macrophages. Int J Tuberc Lung Dis 4, 491-495 (2000)
    • (2000) Int J Tuberc Lung Dis , vol.4 , pp. 491-495
    • Heifets, L.1    Higgins, M.2    Simon, B.3
  • 47
    • 0034982047 scopus 로고    scopus 로고
    • Tuberculosis - Scientific Blueprint for tuberculosis drug development
    • Global Alliance for TB Drug Development: Tuberculosis - Scientific Blueprint for tuberculosis drug development. Tuberculosis, 81, Sup 1, 1-52 (2001)
    • (2001) Tuberculosis , vol.81 , Issue.1 SUPPL. , pp. 1-52
  • 48
    • 0019973896 scopus 로고
    • Glyoxylate metabolism and adaptation of Mycobacterium tuberculosis to survival under anaerobic conditions
    • Wayne L.G. & K-Y. Lin: Glyoxylate metabolism and adaptation of Mycobacterium tuberculosis to survival under anaerobic conditions. Infect Immun 37, 1042-1049 (1982)
    • (1982) Infect Immun , vol.37 , pp. 1042-1049
    • Wayne, L.G.1    Lin, K.-Y.2
  • 49
    • 84965088823 scopus 로고
    • The influence of corticotrophin and cortisone with antituberculous drugs on populations of Mycobacterium tuberculosis in tissues of mice
    • Batten J.C. & R.M. McCune Jr: The influence of corticotrophin and cortisone with antituberculous drugs on populations of Mycobacterium tuberculosis in tissues of mice. Brit J Exp Path 38, 424-437 (1957)
    • (1957) Brit J Exp Path , vol.38 , pp. 424-437
    • Batten, J.C.1    McCune Jr., R.M.2
  • 50
    • 0020537408 scopus 로고
    • Study of chemotherapy regimens of 5 and 7 months' duration and the role of corticosteroids in the treatment of sputum-positive patients with pulmonary tuberculosis in South India
    • Tuberculosis Research Centre, Madras: Study of chemotherapy regimens of 5 and 7 months' duration and the role of corticosteroids in the treatment of sputum-positive patients with pulmonary tuberculosis in South India. Tubercle 64, 73-91 (1983)
    • (1983) Tubercle , vol.64 , pp. 73-91
  • 52
    • 0024434790 scopus 로고
    • Experimental short-course preventive therapy of tuberculosis with rifampin and pyrazinamide
    • Lecoeur H.F., C. Truffot-Pernot & J.H. Grosset: Experimental short-course preventive therapy of tuberculosis with rifampin and pyrazinamide. Am Rev Respir Dis 140, 1189-1193 (1989)
    • (1989) Am Rev Respir Dis , vol.140 , pp. 1189-1193
    • Lecoeur, H.F.1    Truffot-Pernot, C.2    Grosset, J.H.3
  • 55
    • 0023715537 scopus 로고
    • An experimental model of chemotherapy on dormant tuberculous infection, with particular reference to rifampicin
    • Kondo E. & K. Kanai: An experimental model of chemotherapy on dormant tuberculous infection, with particular reference to rifampicin. Japan J Med Sci Biol 41, 37-47 (1988)
    • (1988) Japan J Med Sci Biol , vol.41 , pp. 37-47
    • Kondo, E.1    Kanai, K.2
  • 56
    • 0034956212 scopus 로고    scopus 로고
    • Guest Commentary. Search for new drugs for treatment of tuberculosis
    • Tuberculosis Drug Screening Program: Guest Commentary. Search for new drugs for treatment of tuberculosis. Antimicrob Agents Chemother 45, 1943-1946 (2001)
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 1943-1946
  • 57
    • 0037310195 scopus 로고    scopus 로고
    • Rapid in vivo screening of experimental drugs for tuberculosis using gamma interferon gene-disrupted mice
    • Lenaerts A. J. M., V. Gruppo, J. V. Brooks & I. M. Orme: Rapid in vivo screening of experimental drugs for tuberculosis using gamma interferon gene-disrupted mice. Antimicrob Agents Chemother 47, 783-785 (2003)
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 783-785
    • Lenaerts, A.J.M.1    Gruppo, V.2    Brooks, J.V.3    Orme, I.M.4
  • 58
    • 0036774622 scopus 로고    scopus 로고
    • An ex vivo culture model for screening drug activity against in vivo phenotypes of Mycobacterium tuberculosis
    • Turner D.J., S. L. Hoyle, V. A. Snewin, M-P Gares, I. N. Brown & D. B. Young: An ex vivo culture model for screening drug activity against in vivo phenotypes of Mycobacterium tuberculosis. Microbiology 148, 2929-2936 (2002)
    • (2002) Microbiology , vol.148 , pp. 2929-2936
    • Turner, D.J.1    Hoyle, S.L.2    Snewin, V.A.3    Gares, M.-P.4    Brown, I.N.5    Young, D.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.