Modulation of Cell Growth by the Hepatitis C Virus Nonstructural Protein NS5A

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 12675-12684

  Arima, Nobuyuki ^a,d   Kao, Chien Yuan ^a,e   Licht, Thomas ^b,f   Padmanabhan, Raji ^c   Sasaguri, Yasuyuki ^d   Padmanabhan, R ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^d UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^e Sigma Aldrich Co   (United States)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; ENZYME INHIBITION; GROWTH KINETICS; TUMORS; VIRUSES;

PRECURSORS;

BIOCHEMISTRY;

NONSTRUCTURAL PROTEIN 5A; PHOSPHOPROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; NS 5 PROTEIN, HEPATITIS C VIRUS; NS-5 PROTEIN, HEPATITIS C VIRUS; PROTAMINE KINASE; TETRACYCLINE;

ANIMAL CELL; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL GROWTH; COMPLEX FORMATION; CONTROLLED STUDY; EPITHELIOID CELL; EPITHELIUM CELL; FLOW CYTOMETRY; GROWTH INHIBITION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; LIVER CELL; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; TUMOR CELL CULTURE; ANIMAL; CELL CLONE; CELL CYCLE; CELL DIVISION; CELL LINE; CELL STRAIN 3T3; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HELA CELL; KINETICS; LIVER; METABOLISM; PHYSIOLOGY; RAT;

ANIMALIA; HEPATITIS C VIRUS; MAMMALIA; MURINAE; RNA VIRUSES;

3T3 CELLS; ANIMALS; CELL CYCLE; CELL DIVISION; CELL LINE; CLONE CELLS; GENE EXPRESSION REGULATION, VIRAL; HELA CELLS; HEPACIVIRUS; HUMANS; KINETICS; LIVER; MICE; PROTAMINE KINASE; RATS; TETRACYCLINE; VIRAL NONSTRUCTURAL PROTEINS;

EID: 0035918320     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008329200     Document Type: Article

References (65)

1. Choo, Q. L., Kuo, G., Weiner, A. J., Overby, L. R., Bradley, D. W., and Houghton, M. (1989) Science 244, 359-362
2. Kuo, G., Choo, Q. L., Alter, H. J., Gitnick, G. L., Redeker, A. G., Purcell, R. H., Miyamura, T., Dienstag, J. L., Alter, M. J., Stevens, C. E., et al. (1989) Science 244, 362-364
3. Seeff, L. B. (1997) Hepatology 26, 21S-28S
4. Kiyosawa, K., Sodeyama, T., Tanaka, E., Gibo, Y., Yoshizawa, K., Nakano, Y., Furuta, S., Akahane, Y., Nishioka, K., Purcell, R. H., et al. (1990) Hepatology 12, 671-675
5. Shih, C., Tai, P.-C., Whitehead, W., Hosono, S., Lee, C.-S., and Yang, C.-S. (1997) in Encyclopedia of Cancer II, pp. 824-834, Academic Press, Inc., New York
6. Beard, M. R., Abell, G., Honda, M., Carroll, A., Gartland, M., Clarke, B., Suzuki, K., Lanford, R., Sangar, D. V., and Lemon, S. M. (1999) Hepatology 30, 316-324
7. Hong, Z., Beaudet-Miller, M., Lanford, R. E., Guerra, B., Wright-Minogue, J., Skelton, A., Baroudy, B. M., Reyes, G. R., and Lau, J. Y. (1999) Virology 256, 36-44
8. Kolykhalov, A. A., Agapov, E. V., Blight, K. J., Mihalik, K., Feinstone, S. M., and Rice, C. M. (1997) Science 277, 570-574
9. Lanford, R. E., Sureau, C., Jacob, J. R., White, R., and Fuerst, T. R. (1994) Virology 202, 606-614
10. Yanagi, M., Purcell, R. H., Emerson, S. U., and Bukh, J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 8738-8743
11. Grakoui, A., Wychowski, C., Lin, C., Feinstone, S. M., and Rice, C. M. (1993) J. Virol. 67, 1385-1395
12. Selby, M. J., Choo, Q. L., Berger, K., Kuo, G., Glazer, E., Eckart, M., Lee, C., Chien, D., Kuo, C., and Houghton, M. (1993) J. Gen. Virol. 74, 1103-1113
13. Shukla, D. D., Hoyne, P. A., and Ward, C. W. (1995) Arch. Virol. 140, 1747-1761
14. Behrens, S. E., Tomei, L., and De Francesco, R. (1996) EMBO J. 15, 12-22
15. Kaneko, T., Tanji, Y., Satoh, S., Hijikata, M., Asabe, S., Kimura, K., and Shimotohno, K. (1994) Biochem. Biophys. Res. Commun. 205, 320-326
16. yAsabe, S. I., Tanji, Y., Satoh, S., Kaneko, T., Kimura, K., and Shimotohno, K. (1997) J. Virol. 71, 790-796
17. Hirota, M., Satoh, S., Asabe, S., Kohara, M., Tsukiyama-Kohara, K., Kato, N., Hijikata, M., and Shimotohno, K. (1999) Virology 257, 130-137
18. Tanji, Y., Kaneko, T., Satoh, S., and Shimotohno, K. (1995) J. Virol. 69, 3980-3986
19. Gale, M. J., Jr., Korth, M. J., Tang, N. M., Tan, S. L., Hopkins, D. A., Dever, T. E., Polyak, S. J., Gretch, D. R., and Katze, M. G. (1997) Virology 230, 217-227
20. Ide, Y., Zhang, L., Chen, M., Inchauspe, G., Bahl, C., Sasaguri, Y., and Padmanabhan, R. (1996) Gene (Amst.) 182, 203-211
21. Reed, K. E., Xu, J., and Rice, C. M. (1997) J. Virol. 71, 7187-7197
22. Reed, K. E., Gorbalenya, A. E., and Rice, C. M. (1998) J. Virol. 72, 6199-6206
23. Reed, K. E., and Rice, C. M. (1999) J. Biol. Chem. 274, 28011-28018
24. Tan, S. L., Nakao, H., He, Y., Vijaysri, S., Neddermann, P., Jacobs, B. L., Mayer, B. J., and Katze, M. G. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 5533-5538
25. Tu, H., Gao, L., Shi, S. T., Taylor, D. R., Yang, T., Mircheff, A. K., Wen, Y., Gorbalenya, A. E., Hwang, S. B., and Lai, M. M. (1999) Virology 263, 30-41
26. Ghosh, A. K., Steele, R., Meyer, K., Ray, R., and Ray, R. B. (1999) J. Gen. Virol. 80, 1179-1183
27. Chung, K. M., Lee, J., Kim, J. E., Song, O. K., Cho, S., Lim, J., Seedorf, M., Hahm, B., and Jang, S. K. (2000) J. Virol. 74, 5233-5241
28. Pines, J. (1995) Biochem. J. 308, 697-711
29. Sherr, C. J. (1996) Science 274, 1672-1677
30. Serrano, M., Hannon, G. J., and Beach, D. (1993) Nature 366, 704-707
31. Hannon, G. J., and Beach, D. (1994) Nature 371, 257-261
32. el-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. (1993) Cell 75, 817-825
33. Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K., and Elledge, S. J. (1993) Cell 75, 805-816
34. Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R., and Beach, D. (1993) Nature 366, 701-704
35. Tournier, S., Leroy, D., Goubin, F., Ducommun, B., and Hyams, J. S. (1996) Mol. Biol. Cell 7, 651-662
36. Agarwal, M. L., Agarwal, A., Taylor, W. R., and Stark, G. R. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8493-8497
37. Niculescu, A. B., III, Chen, X., Smeets, M., Hengst, L., Prives, C., and Reed, S. I. (1998) Mol. Cell. Biol. 18, 629-643
38. Dulic, V., Stein, G. H., Far, D. F., and Reed, S. I. (1998) Mol. Cell. Biol. 18, 546-557
39. Huggett, A. C., Ellis, P. A., Ford, C. P., Hampton, L. L., Rimoldi, D., and Thorgeirsson, S. S. (1991) Cancer Res. 51, 5929-5936
40. Chen, H., Campisi, J., and Padmanabhan, R. (1996) J. Biol. Chem. 271, 13959-13967
41. Kao, C. Y., Oakley, C. S., Welsch, C. W., and Chang, C. C. (1997) In Vitro Cell Dev. Biol. Anim. 33, 282-288
42. Frebourg, T., Kassel, J., Lam, K. T., Gryka, M. A., Barbier, N., Andersen, T. I., Borresen, A. L., and Friend, S. H. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 6413-6417
43. Ide, Y., Tanimoto, A., Sasaguri, Y., and Padmanabhan, R. (1997) Gene (Amst.) 201, 151-158
44. Gossen, M., and Bujard, H. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 5547-5551
45. Gallia, G. L., and Khalili, K. (1998) Oncogene 16, 1879-1884
46. Moradpour, D., Englert, C., Wakita, T., and Wands, J. R. (1996) Virology 222, 51-63
47. Moradpour, D., Kary, P., Rice, C. M., and Blum, H. E. (1998) Hepatology 28, 192-201
48. Nishino, Y., Myojin, T., Kamata, M., and Aida, Y. (1997) Biochem. Biophys. Res. Commun. 232, 550-554
49. Nishizawa, M., Myojin, T., Nishino, Y., Nakai, Y., Kamata, M., and Aida, Y. (1999) Virology 263, 313-322
50. Scheffher, M., Werness, B. A., Huibregtse, J. M., Levine, A. J., and Howley, P. M. (1990) Cell 63, 1129-1136
51. Scheffner, M., Huibregtse, J. M., Vierstra, R. D., and Howley, P. M. (1993) Cell 75, 495-505
52. Riabowol, K., Draetta, G., Brizuela, L., Vandre, D., and Beach, D. (1989) Cell 57, 393-401
53. Fang, F., and Newport, J. W. (1991) Cell 66, 731-742
54. Murray, A. W. (1992) Nature 359, 599-604
55. Draetta, G. (1990) Trends Biochem. Sci. 15, 378-383
56. Murray, A. W. (1995) Curr. Opin. Genet. Dev. 5, 5-11
57. Pines, J. (1995) Semin. Cancer Biol. 6, 63-72
58. Morgan, D. O. (1995) Nature 374, 131-134
59. Moss, B., Elroy-Stein, O., Mizukami, T., Alexander, W. A., and Fuerst, T. R. (1990) Nature 348, 91-92
60. Adams, P. D., Sellers, W. R., Sharma, S. K., Wu, A. D., Nalin, C. M., and Kaelin, W. G., Jr. (1996) Mol. Cell. Biol. 16, 6623-6633
61. Guadagno, T. M., and Newport, J. W. (1996) Cell 84, 73-82
62. Shockett, P., Difilippantonio, M., Hellman, N., and Schatz, D. G. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 6522-6526
63. Dulic, V., Kaufmann, W. K., Wilson, S. J., Tlsty, T. D., Lees, E., Harper, J. W., Elledge, S. J., and Reed, S. I. (1994) Cell 76, 1013-1023
64. Sherr, C. J., and Roberts, J. M. (1995) Genes Dev. 9, 1149-63
65. Hengst, L., and Reed, S. I. (1998) Curr. Top. Microbiol. Immunol. 227, 25-41