The human phosphodiesterase PDE10A gene: Genomic organization and evolutionary relatedness with other PDEs containing GAF domains

European Journal of Biochemistry

Volumn 267, Issue 19, 2000, Pages 5943-5951

  Fujishige, Kotomi ^a   Kotera, Jun ^a   Yuasa, Keizo ^a   Omori, Kenji ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Caenorhabditis elegans; Genome; Human; PDE10A; Phosphodiesterase

Indexed keywords

COMPLEMENTARY DNA; GENE PRODUCT; PHOSPHODIESTERASE;

AMINO ACID SEQUENCE; ARTICLE; CAENORHABDITIS ELEGANS; DNA SEQUENCE; ENZYME ACTIVITY; EVOLUTION; GENOME; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CAENORHABDITIS ELEGANS; CLONING, MOLECULAR; CORPUS STRIATUM; EVOLUTION, MOLECULAR; EXONS; GENES; HELMINTH PROTEINS; HUMANS; INTRONS; MALE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PHOSPHORIC DIESTER HYDROLASES; PHYLOGENY; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY; TESTIS; TRANSCRIPTION, GENETIC;

CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 0033797979     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01661.x     Document Type: Article

References (31)

1. Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms
2. Regulation of cAMP and cGMP signaling: New phosphodiesterases and new functions
3. Chimeric constructs shown that the unique N-terminal domain of the cyclic AMP phosphodiesterase RD1 (RNPDE4A1A; rPDE-IVa1) can confer membrane association upon the normally cytosolic protein chloramphenicol acetyltransferase
4. The SH3 domain of src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5)
5. Genomic origin and transcriptional regulation of two variants of cGMP-binding cGMP-specific phosphodiesterases
6. Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation
7. The GAF domain: An evolutionary link between diverse phototransducing proteins
8. Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP
9. Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A
10. Isolation and characterization of human cDNAs encoding a cGMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase
11. Expression, structure and chromosomal localization of the human cGMP-binding cGMP-specific phosphodiesterase PDE5A gene
12. Molecular characterization of human and bovine rod photoreceptor cGMP phosphodiesterase α-subunit and chromosomal localization of the human gene
13. The human β-subunit of rod photoreceptor cGMP phosphodiesterase: Complete retinal cDNA sequence and evidence for expression in brain
14. Human cone-specific cGMP phosphodiesterase α' subunit: Complete cDNA sequence and gene arrangement
15. Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expression
16. Striatum- and testis-specific phosphodiesterase PDE10A: Isolation and characterization of a rat PDE10A
17. Basic local alignment search tool
18. TRANSFAC: An integrated system for gene expression regulation
19. SMART: A Web-based tool for the study of genetically mobile domains
20. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
21. Characterization and phosphorylation of PDE10A2, a novel alternative splice variant of human phosphodiesterase that hydrolyzes cAMP and cGMP
22. Splice junctions, branch point sites and exons: Sequence statistics, identification, and applications to genome project
23. Characterization of the DNA-binding properties of the myeloid zinc finger protein MZF1: Two independent DNA-binding domains recognize two DNA consensus sequences with a common G-rich core
24. Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements
25. Purification and biochemical characterization of the promoter-specific transcription factor, Sp1
26. Genomic organization and complete sequence of the human gene encoding the β-subunit of the cGMP phosphodiesterase and its localization to 4p16.3
27. Cell type-specific regulation of expression of transcription factor AP-2 in neuroectodermal cells
28. Ancient gene duplication and domain shuffling in the animal cyclic nucleotide phosphodiesterase family
29. Neurobiology of the Caenorhabditis elegans genome
30. Functional genomics