FXR-mediated down-regulation of CYP7A1 dominates LXRα in long-term cholesterol-fed NZW rabbits

Journal of Lipid Research

Volumn 44, Issue 10, 2003, Pages 1956-1962

  Xu, Guorong ^a,b   Li, Hai ^b   Pan, Lu Xing ^b   Shang, Quan ^b   Honda, Akira ^c   Ananthanarayanan, M ^d   Erickson, Sandra K ^e   Shneider, Benjamin L ^d   Shefer, Sarah ^b   Bollineni, Jaya ^b   Forman, Barry M ^f   Matsuzaki, Yasushi ^c   Suchy, Frederick J ^f   Tint, G Stephen ^a,b   Salen, Gerald ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

ATP binding cassette transporter A1; Dietary cholesterol; Oxysterol; Short heterodimer partner

Indexed keywords

ABC TRANSPORTER; CELL RECEPTOR; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; FARNESOID X RECEPTOR; LIVER X RECEPTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL INTAKE; CHOLESTEROL METABOLISM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SYNTHESIS; GENE EXPRESSION REGULATION; LIVER METABOLISM; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RABBIT;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; CARRIER PROTEINS; CHOLESTEROL; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CHOLESTEROL ESTER TRANSFER PROTEINS; DNA-BINDING PROTEINS; DOWN-REGULATION; GLYCOPROTEINS; LIGANDS; LIVER; RABBITS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RNA, MESSENGER; STEROID 12-ALPHA-HYDROXYLASE; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 10744226383     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1194/jlr.M300182-JLR200     Document Type: Article

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