Up-regulation of c-myc gene expression following focal ischemia in the rat brain

Neurological Research

Volumn 18, Issue 6, 1996, Pages 559-563

  Nakagomi, Tadayoshi ^a   Asai, Akio ^b   Kanemitsu, Hideaki ^a   Narita, Kouji ^a   Kuchino, Yoshiyuki ^c   Tamura, Akira ^a   Kirino, Takaaki ^a  

^a TEIKYO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

apoptosis; c myc; Focal Ischemia; gene expression; rat

Indexed keywords

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; GENE EXPRESSION; NONHUMAN; ONCOGENE C MYC; RAT; SUPPRESSOR GENE;

EID: 0030447530     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1080/01616412.1996.11740470     Document Type: Article

References (45)

1. Astrup J, Siesjo BK, Symon L. Thresholds in cerebral ischemiathe ischemic penumbra. Stroke 1981; 12: 723-725
2. Hakim AM. The cerebral ischemic penumbra Can J Neurol Sci 1987; 14: 557-559
3. Fujie W, Kirino T, Tomukai N, Iwasawa T, Tamura A. Progressive shrinkage of the thalamus following middle cerebral artery occlusion in rats. Stroke 1990; 21: 1485-1488
4. Nagasawa H, Kogure K. Exo-focal post-ischemic neuronal death in the rat brain. Brain Res 1990; 524: 192-202
5. Tamura A, Kirino T, Sano K, Takagi K, Oka H. Atrophy of the ipsilateral substantia nigra following middle cerebral artery occlusion in the rat Brain Res 1990; 510: 151-157
6. Yamada K, Kinoshita A, Kohmura E, Sakaguchi T, Taguchi J, Kataoka K, Hayakawa T. Basic fibroblast growth factor prevents thalamic degeneration after cortical infarction. J Cereb Blood Flow Metab 1991; 11: 472-478
7. Kerr JFR, Wyllie AH, Currie AH. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239-245
8. Desphande J, Bergstedt K, Linden T, Kalimo H, Wieloch T. Ultrastructural changes in the hippocampal CA1 region following transient cerebral ischemia: Evidence against programmed cell death. Exp Brain Res 1992; 88: 91-105
9. Tominaga T, Kure S, Narisawa K, Yoshimoto T. Endonuclease activation following focal ischemic injury in the rat brain. Brain Res 1993; 608: 21-26
10. Lindquist S, Craig EA. The heat-shock proteins. Annu Rev Genet 1988; 22: 631-677
11. Morimoto RI, Tissieres A, Georgopolus C. The stress response, function of proteins, and perspectives. In: Morimoto RI, Tissieres A, Georgopolus C, eds: Stress Proteins in Biology and Medicine, Cold Spring Harbor Lab Press, 1990: pp. 1-36
12. Kiessling, M, Dienel GD, Jacewicz M, Pulsinelli WA. Protein synthesis in post-ischemic rat brain: A two dimensional electrophoretic analysis. J Cereb Blood Flow Metab 1986; 6: 642-649
13. Kirino T. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res 1982; 239: 57-69
14. Nowak TS Jr., Ikeda J, Nakajima Y. 70-kDa heat-shock protein and c-fos gene expression after transient ischemia. Stroke 1990; 21: 107-111
15. Vass K, Welch WJ, Novak TS Jr., Localization of 70 kDa stress protein in gerbil brain after ischemia. Acta Neuropathol 1988; 77: 128-135
16. Welsh FA, Moyer DJ, Harris VA. Regional expression of heat shock protein-70 and c-fos mRNA following focal ischemia in rat brain. J Cereb Blood Flow Metab 1991; 12: 204-212
17. Jørgensen MB, Deckert J, Wright DC, Gehlert DR. Delayed c-fos proto-oncogene expression in the rat hippocampus induced by transient global ischemia; an in situ hybridization study. Brain Res 1989; 484: 393-398
18. 8 Kindy MS, Carney JP, Dempsey RJ, Carney JM. Ischemic induction of proto-oncogene expression in gerbil brain. J Mol Neurosci 1991; 2: 217-228
19. Onodera H, Kogure K, Ono Y, Igarashi K, Kiyota Y, Nagaoka A. Proto-oncogene c-fos transiently induced in the rat cerebral cortex after forebrain ischemia. Neurosci Lett 1989; 98: 101-104
20. Wessel TC, Joh TH, Volpe BT. In situ hybridization analysis of c-fos and c-jun expression in the rat brain following transient forebrain ischemia. Brain Res 1991; 576: 231-240
21. Angel P, Karin M. The role of Jun, Fos and the AP-1 complex in cell proliferation and transformation. Biochem Biophys Acta 1991; 1072: 129-157
22. Morgan JL, Curran T. Stimulus-transcription coupling in the nervous system: Involvement of the inducible proto-oncogenes fos and jun. Annu Rev Neurosci 1991; 14: 421-451
23. Asai A, Miyagi Y, Sugiyama A, Nagashima Y, Kanemitsu H, Obinata M, Mishima K, Kuchino Y. The s-Myc protein having the activity to induce apoptosis is selectively expressed in rat embryo chondrocytes. Oncogene 1994; 9: 2345-2352
24. Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, Waters CM, Penn LZ, Hancock DC. Induction of apoptosis in fibroblasts by c-myc protein. Cell 1992; 69: 119-128
25. Shi Y, Bisssonnette RP, Glynn JM, Gilbert LJ, Guilbert LJ, Cotter TG, Green DR. Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas. Science 1992; 257: 212-214
26. Garcia I, Martinou I, Tsujimoto Y, Martonou JC. Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 1992; 258: 302-304
27. Vaux DL, Cory S, Adams JM. bcl-2 gene promotes haematopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 1991; 335: 440-442
28. Clarke AR, Purdie CA, Harrison DJ, Morris CC, Hooper ML, Wyllie AH. Thymocyte apoptosis induced by p53 dependent and independent pathways. Nature 1993, 362: 849-852
29. Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T. p-53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 1993; 362: 847-849
30. Tamura A, Graham DI, McCulloch J, Teasdale GM. Focal cerebral ischemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1981; 1: 53-60
31. Church GM, Gilbert W. Genomic sequencing. Proc Natl Acad Sci USA 1984; 81: 1991-1995
32. Kinouchi H, Sharp FR, Chan PH, Koistinaho J, Sager SM, Yoshimoto T. Induction of c-fos, junB, and hsp70 mRNA in cortex, thalamus, basal ganglia, and hippocampus following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1994; 14: 808-817
33. Feeny DM, Baron J-C. Diaschisis. Stroke 1986; 17: 817-830
34. Iijima R, Mies G, Hossmann A. Repeated negative DC deflections in rat cortex following middle cerebral artery occlusion are abolished by MK-801: Effect on volume of ischemic injury. J Cereb Blood Flow Metab 1992; 12: 727-733
35. Nedergaad M, Hansen AJ. Characterization of cortical depolarization evoked in focal cerebral ischemia. J Cereb Blood Flow Metab 1993; 13: 568-574
36. Nowak TS Jr., Synthesis of a stress protein following transient ischemia in the gerbil. J Neurochem 1985; 45: 1635-1641
37. Smeyne RJ, Vendrell M, Hayward M, Baker SJ, Miao GG, Schilling K, Robertson LM, Curran T, Morgan JI. Continuous c-fos expression precedes programmed cell death in vivo. Nature 1993; 363: 166-169
38. Luscher B, Eisenman NA. New light on Myc and Myb. Part I. Myc. Genes Devel 1990; 4: 2025-2035
39. Bisonnetre RP, Shi Y, Mahboubi JM, Glynn JM, Green DR. c-myc and apoptosis. In: Tomei LD, Cope FO, eds. Apoptosis II. The molecular basis of apoptosis in disease, Cold Spring Harbor Lab Press, 1994: pp. 327-356
40. Kerr JFR. Shrinkage necrosis: a distinct mode of cellular death. J Pathol 1971; 105: 13-20
41. Goldstein P, Ojcius DM, Young DE. Cell death mechanism and immune system. Immunol Rev 1991; 121: 29-65
42. Raff MC. Social controls on cell survival and cell death. Nature 1992; 356: 397-400
43. Wyllie AH, Kerr JFR, Cullie AR. Cell death: The significance of apoptosis. Int Rev Cytol 1980; 68: 251-306
44. Wyllie AH, Rose KA, Morris RG, Steel CM, Foster E, Spandidos DA. Rodent fibroblast tumours expressing human myc and ras genes: Growth, metastasis and endogenous oncogene expression. Br J Cancer 1987; 56: 251-259
45. Kingston RE, Baldwin AS Jr., Sharp PA. Regulation of heat-shock protein 70 gene expression by c-myc. Nature 1984; 312: 280-282