Targeting of a histone acetyltransferase domain to a promoter enhances protein expression levels in mammalian cells

Journal of Biotechnology

Volumn 115, Issue 1, 2005, Pages 35-46

  Kwaks, T H J ^a   Sewalt, R G A B ^b   Van Blokland, R ^b   Siersma, T J ^b   Kasiem, M ^b   Kelder, A ^b   Otte, A P ^a,b,c  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b ChromaGenics   (Netherlands)

^c CRUCELL HOLLAND BV   (Netherlands)

Author keywords

Anti repressor elements; Chromatin; Gene silencing; HAT; Protein expression

Indexed keywords

CHROMATIN; MAMMALIAN CELLS; PROTEIN EXPRESSION LEVELS; TRANSFECTED GENES;

CELLS; GENES; PIGMENTS; PROTEINS; VIRUSES;

ENZYME KINETICS;

HISTONE ACETYLTRANSFERASE;

ANIMAL CELL; ARTICLE; CHROMATIN; CONTROLLED STUDY; GENE CONSTRUCT; GENE REPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; REPORTER GENE;

ACETYLTRANSFERASES; ANIMALS; BACTERIAL PROTEINS; CELL CYCLE PROTEINS; CHO CELLS; CRICETINAE; CRICETULUS; GENE TARGETING; GENETIC ENHANCEMENT; HISTONE ACETYLTRANSFERASES; PROMOTER REGIONS (GENETICS); PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SERINE ENDOPEPTIDASES; TRANSCRIPTION FACTORS; TRANSFECTION;

MAMMALIA;

EID: 10644295477     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2004.07.012     Document Type: Article

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