The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation

Genes and Development

Volumn 16, Issue 12, 2002, Pages 1540-1554

  Mutskov, Vesco J ^a   Farrell, Catherine M ^a   Wade, Paul A ^b   Wolffe, Alan P ^c   Felsenfeld, Gary ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BioSciences Inc   (United States)

Author keywords

Chromatin; DNA methylation; Histone acetylation; Insulator; Methyl binding domain (MBD) proteins; Silencing

Indexed keywords

BETA GLOBIN;

ACETYLATION; ANIMAL CELL; ARTICLE; BINDING SITE; CHICKEN; CHROMOSOME; CONTROLLED STUDY; CPG ISLAND; DEACETYLATION; DNA METHYLATION; GENE SEQUENCE; GENE SILENCING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENE;

ACETYLATION; ADENOSINE TRIPHOSPHATASES; ANIMALS; AUTOANTIGENS; BLOTTING, WESTERN; CELL LINE; CELL SEPARATION; CHICKENS; CPG ISLANDS; DNA HELICASES; DNA METHYLATION; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; FLOW CYTOMETRY; GENE SILENCING; GLOBINS; HISTONE DEACETYLASES; HISTONES; MODELS, GENETIC; PLASMIDS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSGENES;

ANIMALIA; GALLUS GALLUS;

EID: 0037098039     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.988502     Document Type: Article

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