메뉴 건너뛰기




Volumn 162, Issue 5, 2004, Pages 554-565

Evidence that unrejoined DNA double-strand breaks are not predominantly responsible for chromosomal radiosensitivity of AT fibroblasts

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA;

EID: 10044245122     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR3255     Document Type: Article
Times cited : (15)

References (71)
  • 1
    • 0024540013 scopus 로고
    • Chromosome instability syndromes
    • M. M. Cohen and H. P. Levy, Chromosome instability syndromes. Adv. Hum. Genet. 18, 43-149 (1989).
    • (1989) Adv. Hum. Genet. , vol.18 , pp. 43-149
    • Cohen, M.M.1    Levy, H.P.2
  • 2
    • 0031060263 scopus 로고    scopus 로고
    • Chromosome instability syndromes: Lessons for carcinogenesis
    • M. S. Meyn, Chromosome instability syndromes: Lessons for carcinogenesis. Curr. Top. Microbiol. Immunol. 221, 72-148 (1997).
    • (1997) Curr. Top. Microbiol. Immunol. , vol.221 , pp. 72-148
    • Meyn, M.S.1
  • 3
    • 1842515632 scopus 로고    scopus 로고
    • A multifaceted role for ATM in genome maintenance
    • T. K. Pandita, A multifaceted role for ATM in genome maintenance. Expert Rev. Mol. Med. 5, 1-20 (2003).
    • (2003) Expert Rev. Mol. Med. , vol.5 , pp. 1-20
    • Pandita, T.K.1
  • 4
    • 0015882277 scopus 로고
    • In vitro chromosomal sensitivity in "chromosomal breakage syndromes"
    • M. Higurashi and P. E. Conen, In vitro chromosomal sensitivity in "chromosomal breakage syndromes". Cancer 32, 380-383 (1973).
    • (1973) Cancer , vol.32 , pp. 380-383
    • Higurashi, M.1    Conen, P.E.2
  • 6
    • 0018644133 scopus 로고
    • Chromosomal radiosensitivity of ataxia telangiectasia cells at different cell cycle stages
    • A. T. Natarajan and M. Meyers, Chromosomal radiosensitivity of ataxia telangiectasia cells at different cell cycle stages. Hum. Genet. 52, 127-132 (1979).
    • (1979) Hum. Genet. , vol.52 , pp. 127-132
    • Natarajan, A.T.1    Meyers, M.2
  • 7
    • 0020587099 scopus 로고
    • Comparison of kinetics of X-ray cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts
    • H. Nagasawa and J. B. Little, Comparison of kinetics of X-ray cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts. Mutat. Res. 109, 297-308 (1983).
    • (1983) Mutat. Res. , vol.109 , pp. 297-308
    • Nagasawa, H.1    Little, J.B.2
  • 8
    • 0021997077 scopus 로고
    • Effect of confluent holding on potentially lethal damage repair cell cycle progression, and chromosomal aberrations in human normal and ataxia-telangiectasia fibroblasts
    • J. B. Little and H. Nagasawa, Effect of confluent holding on potentially lethal damage repair, cell cycle progression, and chromosomal aberrations in human normal and ataxia-telangiectasia fibroblasts. Radiat. Res. 101, 81-93 (1985).
    • (1985) Radiat. Res. , vol.101 , pp. 81-93
    • Little, J.B.1    Nagasawa, H.2
  • 9
    • 0021915522 scopus 로고
    • Effects of X-irradiation on cell-cycle progression, induction of chromosomal aberrations and cell killing in ataxia telangiectasia (AT) fibroblasts
    • H. Nagasawa, S. A. Latt, M. E. Lalande and J. B. Little, Effects of X-irradiation on cell-cycle progression, induction of chromosomal aberrations and cell killing in ataxia telangiectasia (AT) fibroblasts. Mutat. Res. 148, 71-82 (1985).
    • (1985) Mutat. Res. , vol.148 , pp. 71-82
    • Nagasawa, H.1    Latt, S.A.2    Lalande, M.E.3    Little, J.B.4
  • 10
    • 0019164411 scopus 로고
    • n and DNA synthesis in ataxia telangiectasia cells following γ-ray irradiation
    • n and DNA synthesis in ataxia telangiectasia cells following γ-ray irradiation. Nature 287, 745-747 (1980).
    • (1980) Nature , vol.287 , pp. 745-747
    • Edwards, M.J.1    Taylor, A.M.R.2
  • 11
    • 0019166395 scopus 로고
    • Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells
    • J. Houldsworth and M. F. Lavin, Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells. Nucleic Acids Res. 8, 3709-3720 (1980).
    • (1980) Nucleic Acids Res. , vol.8 , pp. 3709-3720
    • Houldsworth, J.1    Lavin, M.F.2
  • 12
    • 0008158443 scopus 로고
    • Radiosensitivity in ataxia-telangiectasia: A new explanation
    • R. B. Painter and B. R. Young, Radiosensitivity in ataxia-telangiectasia: A new explanation. Proc. Natl. Acad. Sci. USA 77, 7315-7317 (1980).
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 7315-7317
    • Painter, R.B.1    Young, B.R.2
  • 13
    • 0019407454 scopus 로고
    • Radioresistant DNA synthesis: An intrinsic feature of ataxia telangiectasia
    • R. B. Painter, Radioresistant DNA synthesis: An intrinsic feature of ataxia telangiectasia. Mutat. Res. 84, 183-190 (1981).
    • (1981) Mutat. Res. , vol.84 , pp. 183-190
    • Painter, R.B.1
  • 14
    • 0019506288 scopus 로고
    • Cell death, chromosome damage and mitotic delay in normal human, ataxia telangiectasia and retinoblastoma fibroblasts after X-irradiation
    • F. Zampetti-Bosseler and D. Scott, Cell death, chromosome damage and mitotic delay in normal human, ataxia telangiectasia and retinoblastoma fibroblasts after X-irradiation. Int. J. Radiat. Biol. 39, 547-558 (1981).
    • (1981) Int. J. Radiat. Biol. , vol.39 , pp. 547-558
    • Zampetti-Bosseler, F.1    Scott, D.2
  • 16
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • R. T. Abraham, Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15, 2177-2196 (2001).
    • (2001) Genes Dev. , vol.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 17
    • 0018820482 scopus 로고
    • Effects of methylated xanthines on mammalian cells treated with bifunctional alkylating agents
    • J. Murnane, J. E. Byfield, J. F. Ward and P. Calabro-Jones, Effects of methylated xanthines on mammalian cells treated with bifunctional alkylating agents. Nature 285, 326-329 (1980).
    • (1980) Nature , vol.285 , pp. 326-329
    • Murnane, J.1    Byfield, J.E.2    Ward, J.F.3    Calabro-Jones, P.4
  • 19
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • D. P. Lane, p53, guardian of the genome. Nature 358, 15-16 (1992).
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 20
    • 0027362909 scopus 로고
    • Cell checkpoint and radiosensitivity
    • J. P. Murnane and J. L. Schwartz, Cell checkpoint and radiosensitivity. Nature 365, 22 (1993).
    • (1993) Nature , vol.365 , pp. 22
    • Murnane, J.P.1    Schwartz, J.L.2
  • 21
    • 0028593976 scopus 로고
    • Cellular radiosensitivity in ataxia-telangiectasia
    • J. Thacker, Cellular radiosensitivity in ataxia-telangiectasia. Int. J. Radiat. Biol. 66, S87-S96 (1994).
    • (1994) Int. J. Radiat. Biol. , vol.66
    • Thacker, J.1
  • 22
    • 0028880649 scopus 로고
    • Ataxia telangiectasia and cellular responses to DNA damage
    • J. M. Brown, M. Stephen Meyn, Ataxia telangiectasia and cellular responses to DNA damage. Cancer Res., 55: 5991-6001, 1995. Cancer Res. 57, 2313-2315 (1997).
    • (1995) Cancer Res. , vol.55 , pp. 5991-6001
    • Brown, J.M.1    Stephen Meyn, M.2
  • 23
    • 0031157079 scopus 로고    scopus 로고
    • J. M. Brown, M. Stephen Meyn, Ataxia telangiectasia and cellular responses to DNA damage. Cancer Res., 55: 5991-6001, 1995. Cancer Res. 57, 2313-2315 (1997).
    • (1997) Cancer Res. , vol.57 , pp. 2313-2315
  • 24
    • 0032404350 scopus 로고    scopus 로고
    • Splitting the ATM: Distinct repair and checkpoint defects in ataxia-telangiectasia
    • P. A. Jeggo, A. M. Carr and A. R. Lehmann, Splitting the ATM: Distinct repair and checkpoint defects in ataxia-telangiectasia. Trends Genet. 14, 312-316 (1998).
    • (1998) Trends Genet. , vol.14 , pp. 312-316
    • Jeggo, P.A.1    Carr, A.M.2    Lehmann, A.R.3
  • 25
    • 0017836044 scopus 로고
    • Deficient recovery from potentially lethal radiation damage in ataxia telangiectasia and xeroderma pigmentosum
    • R. R. Weichselbaum, J. Nove and J. B. Little, Deficient recovery from potentially lethal radiation damage in ataxia telangiectasia and xeroderma pigmentosum. Nature 271, 261-262 (1978).
    • (1978) Nature , vol.271 , pp. 261-262
    • Weichselbaum, R.R.1    Nove, J.2    Little, J.B.3
  • 26
    • 0021997077 scopus 로고
    • Effect of confluent holding on potentially lethal damage repair cell cycle progression, and chromosomal aberrations in human normal and ataxia-telangiectasia fibroblasts
    • J. B. Little and H. Nagasawa, Effect of confluent holding on potentially lethal damage repair, cell cycle progression, and chromosomal aberrations in human normal and ataxia-telangiectasia fibroblasts. Radiat. Res. 101, 81-93 (1985).
    • (1985) Radiat. Res. , vol.101 , pp. 81-93
    • Little, J.B.1    Nagasawa, H.2
  • 27
    • 0021978722 scopus 로고
    • On the nature of a defect in cells from individuals with ataxia-telangiectasia
    • M. N. Cornforth and J. S. Bedford, On the nature of a defect in cells from individuals with ataxia-telangiectasia. Science 227, 1589-1591 (1985).
    • (1985) Science , vol.227 , pp. 1589-1591
    • Cornforth, M.N.1    Bedford, J.S.2
  • 28
    • 0023252949 scopus 로고
    • A quantitative comparison of potentially lethal damage repair and the rejoining of interphase chromosome breaks in low passage normal human fibroblasts
    • M. N. Cornforth and J. S. Bedford, A quantitative comparison of potentially lethal damage repair and the rejoining of interphase chromosome breaks in low passage normal human fibroblasts. Radiat. Res. 111, 385-405 (1987).
    • (1987) Radiat. Res. , vol.111 , pp. 385-405
    • Cornforth, M.N.1    Bedford, J.S.2
  • 29
    • 0029008814 scopus 로고
    • Abnormal radiosensitivity of lymphocytes from breast cancer patients with excessive normal tissue damage after radiotherapy: Chromosome aberrations after low dose-rate irradiation
    • L. A. Jones, D. Scott, R. Cowan and S. A. Roberts, Abnormal radiosensitivity of lymphocytes from breast cancer patients with excessive normal tissue damage after radiotherapy: chromosome aberrations after low dose-rate irradiation. Int. J. Radiat. Biol. 67, 519-528 (1995).
    • (1995) Int. J. Radiat. Biol. , vol.67 , pp. 519-528
    • Jones, L.A.1    Scott, D.2    Cowan, R.3    Roberts, S.A.4
  • 30
    • 0019948367 scopus 로고
    • Structural changes in chromatin as the basis for radiosensitivity in ataxia telangiectasia
    • R. B. Painter, Structural changes in chromatin as the basis for radiosensitivity in ataxia telangiectasia. Cytogenet. Cell Genet. 33, 139-144 (1982).
    • (1982) Cytogenet. Cell Genet. , vol.33 , pp. 139-144
    • Painter, R.B.1
  • 31
    • 0028567026 scopus 로고
    • Possible role of chromatin alteration in the radiosensitivity of ataxia-telangiectasia
    • W. N. Hittelman and T. K. Pandita, Possible role of chromatin alteration in the radiosensitivity of ataxia-telangiectasia. Int. J. Radiat. Biol. 66, S109-113 (1994).
    • (1994) Int. J. Radiat. Biol. , vol.66
    • Hittelman, W.N.1    Pandita, T.K.2
  • 32
    • 0033853835 scopus 로고    scopus 로고
    • Influence of ATM function on interactions between telomeres and nuclear matrix
    • T. K. Pandita and S. Dhar, Influence of ATM function on interactions between telomeres and nuclear matrix. Radiat. Res. 154, 133-139 (2000).
    • (2000) Radiat. Res. , vol.154 , pp. 133-139
    • Pandita, T.K.1    Dhar, S.2
  • 33
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • C. J. Bakkenist and M. B. Kastan, DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421, 499-506 (2003).
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 34
    • 0035691835 scopus 로고    scopus 로고
    • TEL1 from Saccharomyces cerevisiae suppresses chromosome aberrations induced by ionizing radiation in ataxia-telangiectasia cells without affecting cell cycle checkpoints
    • J. P. Cao, M. S. Meyn, F. Eckardt-Schupp and E. Fritz, TEL1 from Saccharomyces cerevisiae suppresses chromosome aberrations induced by ionizing radiation in ataxia-telangiectasia cells without affecting cell cycle checkpoints. Radiat. Environ. Biophys. 40, 309-315 (2001).
    • (2001) Radiat. Environ. Biophys. , vol.40 , pp. 309-315
    • Cao, J.P.1    Meyn, M.S.2    Eckardt-Schupp, F.3    Fritz, E.4
  • 35
    • 0028151744 scopus 로고
    • FISH "painting" patterns resulting from complex exchanges
    • J. R. Savage and P. J. Simpson, FISH "painting" patterns resulting from complex exchanges. Mutat. Res. 312, 51-60 (1994).
    • (1994) Mutat. Res. , vol.312 , pp. 51-60
    • Savage, J.R.1    Simpson, P.J.2
  • 36
    • 0027988574 scopus 로고
    • Identification of X-ray-induced complex chromosome exchanges using fluorescence in situ hybridization: A comparison at two doses
    • P. J. Simpson and J. R. K. Savage, Identification of X-ray-induced complex chromosome exchanges using fluorescence in situ hybridization: A comparison at two doses. Int. J. Radiat. Biol. 66, 629-632 (1994).
    • (1994) Int. J. Radiat. Biol. , vol.66 , pp. 629-632
    • Simpson, P.J.1    Savage, J.R.K.2
  • 37
    • 10044262225 scopus 로고
    • Estimating the true frequency of X-ray-induced complex chromosome exchanges using fluorescence in situ hybridization
    • P. J. Simpson and J. R. K. Savage, Estimating the true frequency of X-ray-induced complex chromosome exchanges using fluorescence in situ hybridization. Int. J. Radiat. Biol. 146, 144-150 (1995).
    • (1995) Int. J. Radiat. Biol. , vol.146 , pp. 144-150
    • Simpson, P.J.1    Savage, J.R.K.2
  • 38
    • 0032905034 scopus 로고    scopus 로고
    • X-ray-induced simple, pseudosimple and complex exchanges involving two distinctly painted chromosomes
    • P. J. Simpson, D. G. Papworth and J. R. K. Savage, X-ray-induced simple, pseudosimple and complex exchanges involving two distinctly painted chromosomes. Int. J. Radiat. Biol. 75, 11-18 (1999).
    • (1999) Int. J. Radiat. Biol. , vol.75 , pp. 11-18
    • Simpson, P.J.1    Papworth, D.G.2    Savage, J.R.K.3
  • 39
    • 0029938407 scopus 로고    scopus 로고
    • Dose-response curves for simple and complex chromosome aberrations induced by X-rays and detected by fluorescence in situ hybridization
    • P. J. Simpson, Dose-response curves for simple and complex chromosome aberrations induced by X-rays and detected by fluorescence in situ hybridization. Int. J. Radiat. Biol. 69, 429-436 (1996).
    • (1996) Int. J. Radiat. Biol. , vol.69 , pp. 429-436
    • Simpson, P.J.1
  • 40
    • 0029912473 scopus 로고    scopus 로고
    • Karyotyping human chromosomes by combinatorial multi-fluor FISH
    • M. R. Speicher, S. G. Ballard and D. C. Ward, Karyotyping human chromosomes by combinatorial multi-fluor FISH. Nat. Genet. 12, 368-375 (1996).
    • (1996) Nat. Genet. , vol.12 , pp. 368-375
    • Speicher, M.R.1    Ballard, S.G.2    Ward, D.C.3
  • 41
    • 0035021725 scopus 로고    scopus 로고
    • Complex chromosome exchanges induced by gamma rays in human lymphocytes: An mFISH study
    • B. D. Loucas and M. N. Cornforth, Complex chromosome exchanges induced by gamma rays in human lymphocytes: An mFISH study. Radiat. Res. 155, 660-671 (2001).
    • (2001) Radiat. Res. , vol.155 , pp. 660-671
    • Loucas, B.D.1    Cornforth, M.N.2
  • 42
    • 0033023801 scopus 로고    scopus 로고
    • Clustering of radiation-produced breaks along chromosomes: Modelling the effects on chromosome aberrations
    • R. K. Sachs, A. M. Chen, P. J. Simpson, L. R. Hlatky, P. Hahnfeldt and J. R. Savage, Clustering of radiation-produced breaks along chromosomes: Modelling the effects on chromosome aberrations. Int. J. Radiat. Biol. 75, 657-672 (1999).
    • (1999) Int. J. Radiat. Biol. , vol.75 , pp. 657-672
    • Sachs, R.K.1    Chen, A.M.2    Simpson, P.J.3    Hlatky, L.R.4    Hahnfeldt, P.5    Savage, J.R.6
  • 43
    • 0035023004 scopus 로고    scopus 로고
    • Analyzing radiation-induced complex chromosome rearrangements by combinatorial painting
    • M. N. Cornforth, Analyzing radiation-induced complex chromosome rearrangements by combinatorial painting. Radiat. Res. 155, 643-659 (2001).
    • (2001) Radiat. Res. , vol.155 , pp. 643-659
    • Cornforth, M.N.1
  • 45
    • 0037964269 scopus 로고    scopus 로고
    • Radiation-induced chromosome aberrations in ataxia telangiectasia cells: High frequency of deletions and misrejoining detected by fluorescence in situ hybridization
    • T. Kawata, H. Ito, K. George, H. Wu, T. Uno, K. Isobe and F. A. Cucinotta, Radiation-induced chromosome aberrations in ataxia telangiectasia cells: High frequency of deletions and misrejoining detected by fluorescence in situ hybridization. Radiat. Res. 159, 597-603 (2003).
    • (2003) Radiat. Res. , vol.159 , pp. 597-603
    • Kawata, T.1    Ito, H.2    George, K.3    Wu, H.4    Uno, T.5    Isobe, K.6    Cucinotta, F.A.7
  • 46
    • 0028073142 scopus 로고
    • Prediction of human cell radiosensitivity: Comparison of clonogenic assay with chromosome aberrations scored using premature chromosome condensation with fluorescence in situ hybridization
    • K. Sasi, J. W. Evans, M. S. Kovacs and J. M. Brown, Prediction of human cell radiosensitivity: Comparison of clonogenic assay with chromosome aberrations scored using premature chromosome condensation with fluorescence in situ hybridization. Int. J. Radiat. Oncol. Phys. 30, 1127-1132 (1994).
    • (1994) Int. J. Radiat. Oncol. Phys. , vol.30 , pp. 1127-1132
    • Sasi, K.1    Evans, J.W.2    Kovacs, M.S.3    Brown, J.M.4
  • 47
    • 0036209939 scopus 로고    scopus 로고
    • Radiosensitivity of ataxia telangiectasia and Nijmegen breakage syndrome homozygotes and heterozygotes as determined by three-color FISH chromosome painting
    • S. Neubauer, R. Arutyunyan, M. Stumm, T. Dork, R. Bendix, M. Bremer, R. Varon, R. Sauer and E. Gebhart, Radiosensitivity of ataxia telangiectasia and Nijmegen breakage syndrome homozygotes and heterozygotes as determined by three-color FISH chromosome painting. Radiat. Res. 157, 312-321 (2002).
    • (2002) Radiat. Res. , vol.157 , pp. 312-321
    • Neubauer, S.1    Arutyunyan, R.2    Stumm, M.3    Dork, T.4    Bendix, R.5    Bremer, M.6    Varon, R.7    Sauer, R.8    Gebhart, E.9
  • 50
    • 0034062867 scopus 로고    scopus 로고
    • Altered splicing of the ATDC message in ataxia telangiectasia group D cells results in the absence of a functional protein
    • H. Tauchi, C. Green, M. Knapp, K. Laderoute and L. Kapp, Altered splicing of the ATDC message in ataxia telangiectasia group D cells results in the absence of a functional protein. Mutagenesis 15, 105-108 (2000).
    • (2000) Mutagenesis , vol.15 , pp. 105-108
    • Tauchi, H.1    Green, C.2    Knapp, M.3    Laderoute, K.4    Kapp, L.5
  • 51
    • 0023138019 scopus 로고
    • Detection of ataxia telangiectasia heterozygous cell lines by postirradiation cumulative labeling index: Measurements with coded samples
    • H. Nagasawa, K. H. Kraemer, Y. Shiloh and J. B. Little, Detection of ataxia telangiectasia heterozygous cell lines by postirradiation cumulative labeling index: Measurements with coded samples. Cancer Res. 47, 398-402 (1987).
    • (1987) Cancer Res. , vol.47 , pp. 398-402
    • Nagasawa, H.1    Kraemer, K.H.2    Shiloh, Y.3    Little, J.B.4
  • 53
    • 0031024783 scopus 로고    scopus 로고
    • Estimation of minimal size of translocated chromosome segments detectable by fluorescence in situ hybridization
    • Y. Kodama, M. Nakano, K. Ohtaki, R. Delongchamp, A. A. Awa and N. Nakamura, Estimation of minimal size of translocated chromosome segments detectable by fluorescence in situ hybridization. Int. J. Radiat. Biol. 71, 35-39 (1997).
    • (1997) Int. J. Radiat. Biol. , vol.71 , pp. 35-39
    • Kodama, Y.1    Nakano, M.2    Ohtaki, K.3    Delongchamp, R.4    Awa, A.A.5    Nakamura, N.6
  • 54
    • 0031851334 scopus 로고    scopus 로고
    • Detection of incomplete exchanges and interstitial fragments in X-irradiated human lymphocytes using a telomeric PNA probe
    • J. J. Boei, S. Vermeulen, J. Fomina and A. T. Natarajan, Detection of incomplete exchanges and interstitial fragments in X-irradiated human lymphocytes using a telomeric PNA probe. Int. J. Radiat. Biol. 73, 599-603 (1998).
    • (1998) Int. J. Radiat. Biol. , vol.73 , pp. 599-603
    • Boei, J.J.1    Vermeulen, S.2    Fomina, J.3    Natarajan, A.T.4
  • 55
    • 0031811750 scopus 로고    scopus 로고
    • Estimate of true incomplete exchanges using fluorescence in situ hybridization with telomere probes
    • H. Wu, K. George and T. C. Yang, Estimate of true incomplete exchanges using fluorescence in situ hybridization with telomere probes. Int. J. Radiat. Biol. 73, 521-527 (1998).
    • (1998) Int. J. Radiat. Biol. , vol.73 , pp. 521-527
    • Wu, H.1    George, K.2    Yang, T.C.3
  • 56
    • 0034078938 scopus 로고    scopus 로고
    • Discrimination between complete and incomplete chromosome exchanges in X-irradiated human lymphocytes using FISH with pan-centromeric and chromosome specific DNA probes in combination with telomeric PNA probe
    • J. Fomina, F. Darroudi, J. J. Boei and A. T. Natarajan, Discrimination between complete and incomplete chromosome exchanges in X-irradiated human lymphocytes using FISH with pan-centromeric and chromosome specific DNA probes in combination with telomeric PNA probe. Int. J. Radiat. Biol. 76, 807-813 (2000).
    • (2000) Int. J. Radiat. Biol. , vol.76 , pp. 807-813
    • Fomina, J.1    Darroudi, F.2    Boei, J.J.3    Natarajan, A.T.4
  • 57
    • 0025836802 scopus 로고
    • Sublethal damage, potentially lethal damage, and chromosomal aberrations in mammalian cells exposed to ionizing radiations
    • J. S. Bedford, Sublethal damage, potentially lethal damage, and chromosomal aberrations in mammalian cells exposed to ionizing radiations. Int. J. Radiat. Oncol. Biol. Phys. 21, 1457-1469 (1991).
    • (1991) Int. J. Radiat. Oncol. Biol. Phys. , vol.21 , pp. 1457-1469
    • Bedford, J.S.1
  • 58
    • 0013974703 scopus 로고
    • Repair of potentially lethal damage in x-irradiated HeLa cells
    • R. A. Phillips and L. J. Tolmach, Repair of potentially lethal damage in x-irradiated HeLa cells. Radiat. Res. 29, 413-432 (1966).
    • (1966) Radiat. Res. , vol.29 , pp. 413-432
    • Phillips, R.A.1    Tolmach, L.J.2
  • 59
    • 0014688062 scopus 로고
    • Repair of sublethal and potentially lethal radiation damage in plateau phase cultures of human cells
    • J. B. Little, Repair of sublethal and potentially lethal radiation damage in plateau phase cultures of human cells. Nature 224, 804-806 (1969).
    • (1969) Nature , vol.224 , pp. 804-806
    • Little, J.B.1
  • 60
    • 0031170827 scopus 로고    scopus 로고
    • Essential and perilous: V(D)J recombination and DNA damage checkpoints in lymphocyte precursors
    • J. S. Danska and C. J. Guidos, Essential and perilous: V(D)J recombination and DNA damage checkpoints in lymphocyte precursors. Semin. Immunol. 9, 199-206 (1997).
    • (1997) Semin. Immunol. , vol.9 , pp. 199-206
    • Danska, J.S.1    Guidos, C.J.2
  • 61
    • 0032568213 scopus 로고    scopus 로고
    • Human normal peripheral blood B-lymphocytes are deficient in DNA-dependent protein kinase activity due to the expression of a variant form of the Ku86 protein
    • C. Muller, C. Dusseau, P. Calsou and B. Salles, Human normal peripheral blood B-lymphocytes are deficient in DNA-dependent protein kinase activity due to the expression of a variant form of the Ku86 protein. Oncogene 16, 1553-1560 (1998).
    • (1998) Oncogene , vol.16 , pp. 1553-1560
    • Muller, C.1    Dusseau, C.2    Calsou, P.3    Salles, B.4
  • 62
    • 0036240127 scopus 로고    scopus 로고
    • The mechanism and regulation of chromosomal V(D)J recombination
    • C. H. Bassing, W. Swat and F. W. Alt, The mechanism and regulation of chromosomal V(D)J recombination. Cell 109, S45-55 (2002).
    • (2002) Cell , vol.109
    • Bassing, C.H.1    Swat, W.2    Alt, F.W.3
  • 63
    • 0028846648 scopus 로고
    • Radiation-induced apoptosis: Relevance to radiotherapy
    • W. C. Dewey, C. C. Ling and R. E. Meyn, Radiation-induced apoptosis: Relevance to radiotherapy. Int. J. Radiat. Biol. 33, 781-796 (1995).
    • (1995) Int. J. Radiat. Biol. , vol.33 , pp. 781-796
    • Dewey, W.C.1    Ling, C.C.2    Meyn, R.E.3
  • 64
    • 0028980555 scopus 로고
    • Different sensitivity to cell killing and chromosome mutation induction by gamma rays in two human lymphoblastoid cell lines derived from a single donor: Possible role of apoptosis
    • J. L. Schwartz, R. Jordan, B. A. Sedita, M. J. Swenningson, J. P. Banath and P. L. Olive, Different sensitivity to cell killing and chromosome mutation induction by gamma rays in two human lymphoblastoid cell lines derived from a single donor: Possible role of apoptosis. Mutagenesis 10, 227-233 (1995).
    • (1995) Mutagenesis , vol.10 , pp. 227-233
    • Schwartz, J.L.1    Jordan, R.2    Sedita, B.A.3    Swenningson, M.J.4    Banath, J.P.5    Olive, P.L.6
  • 65
    • 0017819141 scopus 로고
    • Unrepaired DNA strand breaks in irradiated ataxia telangiectasia lymphocytes suggested from cytogenetic observations
    • A. M. R. Taylor, Unrepaired DNA strand breaks in irradiated ataxia telangiectasia lymphocytes suggested from cytogenetic observations. Mutat. Res. 50, 407-418 (1978).
    • (1978) Mutat. Res. , vol.50 , pp. 407-418
    • Taylor, A.M.R.1
  • 67
    • 0019959280 scopus 로고
    • DNA double strand breaks in Ehrlich ascites tumour cells at low doses of x-rays. I. Determination of induced breaks by centrifugation at reduced speed
    • D. Blocher, DNA double strand breaks in Ehrlich ascites tumour cells at low doses of x-rays. I. Determination of induced breaks by centrifugation at reduced speed. Int. J. Radiat. Biol. 42, 317-328 (1982).
    • (1982) Int. J. Radiat. Biol. , vol.42 , pp. 317-328
    • Blocher, D.1
  • 68
    • 0017190405 scopus 로고
    • The production and repair of double strand breaks in cells from normal humans and from patients with ataxia telangiectasia
    • A. R. Lehman and S. Stevens, The production and repair of double strand breaks in cells from normal humans and from patients with ataxia telangiectasia. Biochim. Biophys. Acta 474, 49-60 (1977).
    • (1977) Biochim. Biophys. Acta , vol.474 , pp. 49-60
    • Lehman, A.R.1    Stevens, S.2
  • 69
    • 0025151450 scopus 로고
    • The rejoining of double-strand breaks in DNA by human cell extracts
    • P. North, A. Ganesh and J. Thacker, The rejoining of double-strand breaks in DNA by human cell extracts. Nucleic Acids Res. 18, 6205-6210 (1990).
    • (1990) Nucleic Acids Res. , vol.18 , pp. 6205-6210
    • North, P.1    Ganesh, A.2    Thacker, J.3
  • 70
    • 0029128223 scopus 로고
    • Induction and rejoining of DNA double-strand breaks and interphase chromosome breaks after exposure to X rays in one normal and two hypersensitive human fibroblast cell lines
    • C. Badie, G. Iliakis, N. Foray, G. Alsbeih, B. Cedervall, N. Chavaudra, G. Pantelias, C. Arlett and E. P. Malaise, Induction and rejoining of DNA double-strand breaks and interphase chromosome breaks after exposure to X rays in one normal and two hypersensitive human fibroblast cell lines. Radiat. Res. 144, 26-35 (1995).
    • (1995) Radiat. Res. , vol.144 , pp. 26-35
    • Badie, C.1    Iliakis, G.2    Foray, N.3    Alsbeih, G.4    Cedervall, B.5    Chavaudra, N.6    Pantelias, G.7    Arlett, C.8    Malaise, E.P.9
  • 71
    • 0344286677 scopus 로고    scopus 로고
    • Joining of correct and incorrect DNA double-strand break ends in normal human and ataxia telangiectasia fibroblasts
    • M. Lobrich, M. Kuhne, J. Wetzel and K. Rothkamm, Joining of correct and incorrect DNA double-strand break ends in normal human and ataxia telangiectasia fibroblasts. Genes Chromosom. Cancer 27, 59-68 (2000).
    • (2000) Genes Chromosom. Cancer , vol.27 , pp. 59-68
    • Lobrich, M.1    Kuhne, M.2    Wetzel, J.3    Rothkamm, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.