Radiation-induced chromosome breaks in ataxia-telangiectasia cells remain open

International Journal of Radiation Biology

Volumn 79, Issue 3, 2003, Pages 203-210

  Martin M ^a   Genesca A ^a   Latre, L ^a   Ribas, M ^b   Miro R ^a   Egozcue, J ^a   Tusell, L ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b HS Pau de Barcelona   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE NUCLEIC ACID; TELOMERASE;

ARTICLE; ATAXIA TELANGIECTASIA; CELL CYCLE; CENTROMERE; CHROMOSOME BREAKAGE; CHROMOSOME DELETION; CONTROLLED STUDY; DNA REPAIR; FLUORESCENCE IN SITU HYBRIDIZATION; HEALING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RADIATION EXPOSURE; TELOMERE;

ATAXIA TELANGIECTASIA; CHROMOSOME ABERRATIONS; CHROMOSOMES; DNA DAMAGE; DNA REPAIR; GAMMA RAYS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; METAPHASE; MICROSCOPY, FLUORESCENCE; TELOMERE;

ATAXIA; ATAXIA TELANGIECTASIA;

EID: 0038748324     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/0955300031000089601     Document Type: Article

References (38)

1. BAILEY, S. M., MEYNE, J., CHEN, D. J., KURIMASA, A., LI, G. C., LEHNERT, B. E. and GOODWIN, E. H., 1999, DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes. Proceedings of the National Academy of Sciences, USA, 96, 14899-14904.
2. BLACKBURN, E. H., 1991, Structure and function of telomeres. Nature, 350, 569-573.
3. BLASCO, M. A., LEE, H.-W, HANDE, P., SAMPER, E., LANSDORP, P., DEPINHO, R. and GREIDER, C. W, 1997, Telomere shortening and tumor formation by mouse cells lacking tetomerase RNA. Cell, 91, 25-34.
4. BOEI, J. J. W, A., VERMEULEN, S. and NATARAJAN, A. T., 2000, Analysis of radiation-induced chromosomal aberrations using telomeric and centromeric PNA probes. International Journal of Radiation Biology, 76, 163-167.
5. CORNFORTH, M. N. and BEDFORD, J. S., 1985, On the nature of a defect in cells from individuals with ataxia-telangiectasia. Science, 227, 1589-1591.
6. D'ADDA DI FAGAGNA, F., HANDE, M. P., TONG, W., ROTH, D., LANSDORP, P. M., WANG, Z. and JACKSON, S. P., 2001, Effects of DNA nonhomologous end joining on telomere length and chromosomal instability in mammalian cells. Current Biology, 11, 1192-1196.
7. DEPINHO, R. A., 2000, The age of cancer. Nature 408, 248-254.
8. EILS, R., UHRIG, S., SARACOGLU, K., SÄTZLER, K., BOLZER, A., PETERSEN, I., CHASSERY, J. M., GANSER, M. and SPEICHER, M. R., 1998, An optimized, fully automated system for fast and accurate identification of chromosomal rearrangements by multiplex-FISH (M-FISH). Cytogenetics and Cell Genetics, 82, 160-171.
9. FAUTH, C. and SPEICHER, M. R., 2001, Classifying by colors: FISH-based genome analysis. Cytogenetics and Cell Genetics, 93, 1-10.
10. FINNON, P., WONG, H.-P., SILVER, A. R. J., SLIJEPCEVIC, P. and BOUFFLER, S. D., 2001, Long but disfunctional telomeres correlate with chromosomal radiosensitivity in a mouse AML cell line. International Journal of Radiation Biology, 77, 1151-1162.
11. FLINT, J., CRADDOCK, C. F., VILLEGAS, A., BENTLY, D. P., WILLIAMS, H. J., GALANELLO, R., CAO, A., WOOD, M. G., AYYUB, H. and HIGGS, D. R., 1994, Healing of broken chromosomes by the addition of telomeric repeats. Journal of Human Genetics, 55, 505-512.
12. GATEI, M., YOUNG, D., CEROSALETTI, K. M., DESAI-MEHTA, A., SPRING, K., KOZLOV, S., LAVIN, M. F., GATTI, R. A., CONCANNON, P. and KHANA, K., 2000, ATM-dependent phosphorylation of nibrin in response to radiation exposure. Nature Genetics, 25, 115-119.
13. GOYTISOLO, F. A., SAMPER, E., EDMONSON, S., TACCIOLI, G. E. and BLASCO, M. A., 2001, The absence of DNA-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang. Molecular Cell Biology, 21, 3642-3651.
14. GRIFFITH, J. D., COMEAU, L., ROSENFIELD, S., STANSEL, R. M., BIANCHI, A., MOSS, H. and DE LANGE, T., 1999, Mammalian telomeres end in a large duplex loop. Cell, 97, 503-514.
15. HANDE, M. P., SAMPER, E., LANSDORP, P. and BLASCO, M. A., 1999, Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice. Journal of Cell Biology, 144, 589-601.
16. KIM, N. W., PIATYSZEK, M. A., PROWSE, K. R., HARLEY, C. B., WEST, M. D., HO, P. L. C., COVIELLO, G. M., WRIGHT, W. E., WEINRICH, S. L. and SHAY, J. W., 1994, Specific association of human telomerase activity with immortal cells and cancer. Science, 266, 2011-2015.
17. LETEURTRE, F., LI, X., GLUCKMAN, E. and CAROSELLA, D. E., 1997, Telomerase activity during the cell cycle and in gamma-irradiated hematopoietic cells. Leukemia, 11, 1681-1689.
18. LIM, D. S., KIM, S. T., XU, B., MASER, R. S., LIN, J., PETRINI, J. H. and KASTAN, M. B. 2000, ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway. Nature, 404, 613-617.
19. MASER, R. S., MONSEN, K. J., NELMS, B. E. and PETRINI, J. H., 1997, HMrel1 and hRad50 nuclear foci are induced during normal cellular response to DNA double-strand breaks. Molecular and Cellular Biology, 17, 6087-6096.
20. MICHELSON, R. J. and WEINERT, T., 2000, Closing the gaps among a web of DNA repair disorders. BioEssays, 22, 966-969.
21. 2 ataxia telangiectasia cells exposed to X-rays and ara A. International Journal of Radiation Biology, 55, 71-84.
22. NELMS, B. E., MASER, R. S., MACKAY, J. F., LAGALLY, M. G. and PETRINI, J. H., 1998, In situ visualization of DNA double-strand break repair in human fibroblasts. Science, 280, 590-592.
23. NEUBAUER, S., ARUTYUNYAN, R., STUMM, M., DORK, T., BENDIX, R., BREMER, M., VARON, R., SAUER, R. and GEBHART, E., 2002, Radiosensitivity of ataxia telangiectasia and Nijmegen breakage syndrome homozygotes and heterozygotes as determined by three-color FISH chromosome painting. Radiation Research, 157, 312-321.
24. PANDITA, T. J., 2002, ATM function and telomere stability. Oncogene 21, 611-618.
25. PANDITA, T. K. and HITTELMAN, W. N., 1992, Initial chromosome damage but not DNA damage is greater in ataxia telangieotasia cells. Radiation Research, 130, 94-103.
26. PANDITA, T. K., PATHAK, S. and GEARD, C. R., 1995, Chromosome end associations, telomeres and telomerase activity in ataxia-telangiectasia cells. Cytogenetics and Cell Genetics, 71, 86-93.
27. PRESTON, R. J. 1997, Telomeres, telomerase and chromosome stability. Radiation Research, 147, 529-534.
28. RUDOLPH, K. L., MILLARD, M., BOSENBERG, M. W. and DEPINHO, R. A., 2001, Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nature Genetics, 28, 155-159.
29. SAMPER, E., GOYTISOLO, F. A., SLIJEPCEVIC, P., VAN BUUL, P. P. W. and BLASCO, M. A., 2000, Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang. EMBO Reports, 1, 244-252.
30. SLIJEPCEVIC, P., NATARAJAN, A. T. and BRYANT, P. E., 1998, Telomeres and radiation-induced chromosome breakage. Mutagenesis, 13, 48-49.
31. SPRUNG, C. N., REYNOLDS, G. E., JASIN, M. and MURNANE, J. P., 1939, Chromosome healing in mouse embryonic stem cells. Proceedings of the National Academy of Sciences, USA, 96, 6781-6786.
32. STUMM, M., NEUBAUER, S., KEINDORFF, S., WEGNER, R.-D., WIEACKER, P. and SAUER, R., 2001, High frequency of spontaneous translocations revealed by FISH in cells from patients with the cancer-prone syndromes ataxia telangiectasia and Nijmegen breakage syndrome. Cytogenetics and Cell Genetics, 92, 186-191.
33. WAGHRAY, M., GASCON, G. G., AL-SEDAIRY, S. and HANNAN, M. A., 1991, Cytogenetic investigations in three cell types of a Saudi family with ataxia telangiectasia. Human Genetics, 87, 285-289.
34. WANG, X., LIU, Y., CHOW, L. S., WONG, S. C., TSAO, G. S., KWONG, D. L., SHAM, J. S. and NICHOLLS, J. M., 2000, Regulation of telomerase activity by gamma-radiation in nasopharyngeal carcinoma cells. Anticancer Research, 20, 433-437.
35. WONG, A. C., NING, Y., FLINT, J., CLARK, K., DUMANSKI, J. P., LEDBETTER, D. H. and MCDERMID, H. E., 1997. Molecular characterization of a 130-kb terminal microdeletion at 22q in a child with mild mental retardation. American Journal of Human Genetics, 60, 113-120.
36. WONG, J. M., KUSDRA, L. and COLLINS, K., 2002, Subnuclear shuttling of human telomerase induced by transformation and DNA damage. Nature Cell Biology, 4, 731-736.
37. WU, X., RANGANATHAN, V., WEISMAN, D. S., HEINE, W. F., CICCONE, D. N., O'NEILL, T. B., CRICK, K. E., PIERCE, K. A., LANE, W. S., RATHBUN, G., LIVINGSTON, D. M. and WEAVER, D. T. 2000, ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature, 405, 477-482.
38. ZHAO, S., WENG, Y. C., YUAN, S. S., LIN, Y. T., HSU, H. C., LIN, S. C., GERBINO, E., SONG, M. H., ZDZIENICKA, M. Z., GATTI, R. A., SHAY, J. W., ZIV, Y., SHILOH, Y. and LEE, E. Y., 2000, Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products. Nature, 405, 473-477.