Complex chromosome exchanges induced by gamma rays in human lymphocytes: An mFISH study

Radiation Research

Volumn 155, Issue 5, 2001, Pages 660-671

  Loucas, B D ^a   Cornforth, M N ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME ANALYSIS; CHROMOSOME PAINTING; CHROMOSOME TRANSLOCATION; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GAMMA RADIATION; HUMAN; HUMAN CELL; KARYOTYPE; LYMPHOCYTE; PRIORITY JOURNAL; RADIATION DOSE;

EID: 0035021725     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2001)155[0660:CCEIBG]2.0.CO;2     Document Type: Article

References (59)

1. The relationship between specific chromosome aberrations and radiation-induced mutations in cultured mammalian cells
2. The chromosomal basis of human neoplasia
3. Sublethal damage, potentially lethal damage and chromosome aberrations in mammalian cells exposed to ionizing radiations
4. The theory of dual radiation action
5. Ionizing radiation damage and its early development in chromosomes
6. Analyzing radiation-induced complex chromosome rearrangements by combinatorial painting
7. FISH "painting" patterns resulting from complex exchanges
8. Classification and relationships of induced chromosomal structural changes
9. Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization
10. Rapid human chromosome aberration analysis using fluorescence in situ hybridization
11. Rapid metaphase and interphase detection of radiation-induced chromosome aberrations in human lymphocytes by chromosomal suppression in situ hybridization
12. The use of fluorescence in situ hybridisation combined with premature chromosome condensation for the identification of chromosome damage
13. Frequencies of X-ray-induced chromosome translocations in human peripheral lymphocytes as detected by in situ hybridization using chromosome-specific DNA libraries
14. Radiation-induced chromosome aberrations analysed by fluorescence in situ hybridization with a triple combination of composite whole chromosome-specific DNA probes
15. Mechanisms of chromosome exchange formation in human fibroblasts: Insights from "chromosome painting"
16. Visualization of nonreciprocal chromosome exchanges in irradiated human fibroblasts by fluorescence in situ hybridization
17. Using three-color chromosome painting to test chromosome aberration models
18. On the scoring of FISH-"painted" chromosome-type exchange aberrations
19. Identification of X-ray-induced complex chromosome exchanges using fluorescence in situ hybridization: A comparison at two doses
20. Estimating the true frequency of X-ray-induced complex chromosome exchanges using fluorescence in situ hybridization
21. Ultrasoft 1.5 keV aluminum K X rays are efficient producers of complex chromosome exchange aberrations as revealed by fluorescence in situ hybridization
22. Dose-response curves for simple and complex chromosome aberrations induced by X-rays and detected by fluorescence in situ hybridization
23. X-ray-induced simple, pseudosimple and complex exchanges involving two distinctly painted chromosomes
24. Clustering of radiation-produced breaks along chromosomes: Modelling the effects on chromosome aberrations
25. Analysis for DNA-proportional distribution of radiation-induced chromosome aberrations in various triple combinations of human chromosomes using fluorescence in situ hybridization
26. Fluorescence in situ hybridization detection of chromosomal aberrations in human lymphocytes: Applicability to biological dosimetry
27. Karyotyping human chromosomes by combinatorial multi-fluor FISH
28. An optimized, fully automated system for fast and accurate identification of chromosomal rearrangements by multiplex-FISH (MFISH)
29. Rapid detection of radiation-induced chromosomal aberrations in lymphocytes and hematopoietic progenitor cells by mFISH
30. A proposed system for scoring structural aberrations detected by chromosome painting
31. Estimation of minimal size of translocated chromosome segments detectable by fluorescence in situ hybridization
32. Detection of incomplete exchanges and interstitial fragments in X-irradiated human lymphocytes using a telomeric PNA probe
33. Frequency of reciprocal translocations and dicentrics induced by fluorescence in situ hybridization
34. X-ray biological dosimetry performed by selective painting of human chromosomes 1 and 2
35. Validation of chromosome painting II. A detailed analysis of aberrations following high doses of ionizing radiation in vitro
36. Estimate of true incomplete exchanges using fluorescence in situ hybridization with telomere probes
37. Chromosome aberrations in human lymphocytes: Effect of radiation quality, dose, and dose rate
38. Current status of cytogenetic procedures to detect and quantify previous exposures to radiation
39. Identification with G and R banding of the position of breakage points induced in human chromosomes by in vitro X-irradiation
40. Assignment of aberration breakpoints in banded chromosomes
41. Frequency and distribution studies of asymmetrical versus symmetrical chromosome aberrations
42. Radiation-induced damage, repair and exchange formation in different chromosomes of human fibroblasts determined by fluorescence in situ hybridization
43. A comparison of the yields of translocations and dicentrics measured using fluorescence in situ hybridization
44. Theoretical predictions on the equality of radiation-produced dicentrics and translocations detected by chromosome painting
45. 60Co gamma ray dose-response for chromosomal aberrations analysed by FISH; applicability to biological dosimetry
46. 0 human lymphocytes and their fate through mitotic divisions in culture
47. Validation of chromosome painting as a biodosimeter in human peripheral lymphocytes following acute exposure to ionizing radiation in vitro
48. Radiation-induced chromosome aberrations analysed by two-color in situ hybridization with composite whole chromosome-specific DNA probes and a pancentromeric DNA probe
49. Mechanisms of induction of chromosomal aberrations and their detection by fluorescence in situ hybridization
50. Analysis of human lymphocyte cell cycle time in culture measured by sister chromatid differential staining
51. Radiation-induced breakpoint misrejoining in human chromosomes: Random or non-random?
52. The mechanism of the induction by radiation of chromosome aberrations in Tradescantia
53. Chromosome aberrations induced by X-rays
54. An analysis of X-ray induced chromosomal aberrations in Tradescantia
55. The rejoining of DNA double-strand breaks and a model for the formation of chromosomal rearrangements
56. Radiation induced chromosome aberrations: Some biophysical considerations
57. Effectiveness of 0.28 keV carbon K ultrasoft X-rays at producing simple and complex chromosome exchanges in human fibroblasts in vitro detected using FISH
58. Reply to letter from Chadwick and Leenhouts: On the dose-effect relationship of true simple chromosomal rearrangements