Influence of ATM function on interactions between telomeres and nuclear matrix

Radiation Research

Volumn 154, Issue 2, 2000, Pages 133-139

  Pandita, T K ^a   Dhar, S ^a  

^a Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ATAXIA TELANGIECTASIA; CELL NUCLEUS MATRIX; CONFERENCE PAPER; DNA DETERMINATION; DNA SEQUENCE; FIBROBLAST; GENE MUTATION; GENETIC ANALYSIS; GENETIC COMPLEMENTATION; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; TELOMERE;

ANIMALIA; ATAXIA; ATAXIA TELANGIECTASIA; MAMMALIA;

EID: 0033853835     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2000)154[0133:ioafoi]2.0.co;2     Document Type: Conference Paper

References (44)

1. D. G. Harnden, The nature of ataxia-telangiectasia: Problems and perspectives. Int. J. Radiat. Biol. 66, S13-S19 (1994).
2. Y. Shiloh, Ataxia-telangiectasia: Closer to unraveling the mystery. Eur. J. Hum. Genet. 3, 116-138 (1995).
3. 1 cell cycle checkpoint pathway and ataxia-telangiectasia. Cancer Res. 54, 5054-5058 (1994).
4. C. E. Canman, D. S. Lim, K. A. Cimprich, Y. Taya, K. Tamai, K. Sakaguchi, E. Appella, M. B. Kastan and J. D. Siliciano, Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281, 1677-1679 (1998).
5. A. J. Giaccia and M. B. Kastan, The complexity of p53 modulation: Emerging patterns from divergent signals. Genes Dev. 12, 2973-2983 (1998).
6. S. Banin, L. Moyal, S. Shieh, Y. Taya, C. W. Anderson, L. Chessa, N. I. Smorodinsky, C. Prives, Y. Reiss and Y. Ziv, Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281, 1674-1677 (1998).
7. 1 arrest. Cell 76, 1013-1023 (1994).
8. K. K. Khanna, K. E. Keating, S. Kozlov, S. Scott, M. Gatei, K. Hobson, Y. Taya, B. Gabrielli, D. Chan and M. F. Lavin, ATM associates with and phosphorylates p53: Mapping the region of interaction. Nat. Genet. 20, 398-400 (1998).
9. H. Beamish, R. Williams, P. Chen and M. F. Lavin, Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation. J. Biol. Chem. 271, 20486-20493 (1996).
10. Y. Xu, T. Ashley, E. E. Brainerd, R. T. Bronson, M. S. Meyn and D. Baltimore, Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects and thymic lymphoma. Genes Dev. 10, 2401-2410 (1996).
11. T. K. Pandita, S. Pathak and C. Geard, Chromosome end association, telomeres and telomerase activity in ataxia telangiectasia cells. Cytogenet. Cell. Genet. 71, 86-93 (1995).
12. T. K. Pandita, E. J. Hall, T. K. Hei, M. A. Piatyszek, W. E. Wright, C. Q. Piao, R. K. Pandila, J. C. Willey, C. R. Geard and J. W. Shay, Chromosome end-to-end associations and telomerase activity during cancer progression in human cells after treatment with α-particles simulating radon progeny. Oncogene 13, 1423-1430 (1996).
13. L. B. Smilenov, S. E. Morgan, W. Mellado, S. G. Sawant, M. B. Kastan and T. K. Pandita, Influence of ATM function on telomere metabolism. Oncogene 15, 2659-2665 (1997).
14. T. L. Kojis, R. A. Gatti and R. S. Sparkes, The cytogenetics of ataxia telangiectasia. Cancer Genet. Cytogenet. 56, 143-156 (1991).
15. C. M. Counter, A. A. Avilion, C. E. LeFeuvre, N. G. Stewart, C. W. Greider, C. B. Harley and S. Bacchetti, Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11, 1921-1929 (1992).
16. V. A. Zakian, Structure and function of telomeres. Annu. Rev. Genet. 23, 579-604 (1989).
17. V. A. Zakian, Saccharomyces telomeres: Function, structure and replication. In Telomeres (E. H. Blackburn and C. W. Greider, Eds.), pp. 107-138. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1995.
18. E. H. Blackburn, Structure and function of telomeres. Nature 350, 569-573 (1991).
19. E. H. Blackburn, The telomere and telomerase: Nucleic acid-protein complexes acting in a telomere homeostasis system. Biochemistry 62, 1196-1201 (1997).
20. L. L. Sandel and V. A. Zakian, Loss of a yeast telomere: Arrest, recovery and chromosome loss. Cell 75, 729-739 (1993).
21. J. B. Stavenhagen and V. A. Zakian, Yeast telomeres exert a position effect on recombination between internal tracts of yeast telomeric DNA. Genes Dev. 12, 3044-3058 (1998).
22. W. E. Wright and J. W. Shay, Telomere positional effects and the regulation of cellular senescence. Trends Genet. 8, 193-197 (1992).
23. T. K. Pandita and D. DeRubeis, Spontaneous amplification of interstitial telomeric bands in Chinese hamster ovary cells. Cytogenet. Cell. Genet. 68, 95-101 (1995).
24. M. E. E. Luderus, B. van Steensel, L. Chong, O. C. M. Sibon, F. F. M. Cremers and T. de Lange, Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex. J. Cell. Biol. 135, 867-881 (1996).
25. L. B. Smilenov, S. Dhar and T. K. Pandita, Altered telomere nuclear matrix interactions and nucleosomal periodicity in cells derived from individuals with ataxia telangiectasia before and after ionizing radiation treatment. Mol. Cell. Biol. 19, 6963-6971 (1999).
26. S. E. Morgan, C. Lovly, T. K. Pandita, Y. Shiloh and M. B. Kastan, Fragments of ATM which have dominant-negative or complementing activity. Mol. Cell. Biol. 17, 2020-2029 (1997).
27. Y. Ziv, A. Bar-Shira, I. Pecker, P. Russell, T. J. Jorgensen, I. Tsarfati and Y. Shiloh, Recombinant ATM protein complements the cellular A-T phenotype. Oncogene 15, 159-167 (1997).
28. T. K. Pandita, C. H. Westphal, M. Anger, S. G. Sawant, C. R. Geard, R. K. Pandita and H. Scherthan, Atm inactivation results in aberrant telomere clustering during meiotic prophase. Mol. Cell. Biol. 19, 5096-5105 (1999).
29. P. A. Dijkwel and J. L. Hamlin, Matrix attachment regions are positioned near replication initiation sites, genes, and an interamplicon junction in the amplified dihydrofolate reductase domain of Chinese hamster ovary cells. Mol. Cell. Biol. 8, 5398-5409 (1988).
30. L. B. Smilenov, W. Mellado, P. H. Rao, S. G. Sawant, C. B. Umbricht, S. Sukumar and T. K. Pandita, Molecular cloning and chromosomal localization of Chinese hamster telomeric protein chTRF1: Its potential role in chromosomal instability. Oncogene 17, 2137-2142 (1998).
31. S. G. Sawant, V. Gregiore, S. Dhar, C. B. Umbricht, S. Cvilic, S. Sukumar and T. K. Pandita, Telomerase activity as a measure for monitoring radiocurability of tumor cells. FASEB J. 13, 1047-1054 (1999).
32. E. J. Hall, P. B. Schiff, G. E. Hanks, D. J. Brenner, J. Russo, J. Chen, S. G. Sawant and T. K. Pandita, A preliminary report: Frequency of A-T heterozygotes among prostate cancer patients with severe late responses to radiation therapy. Cancer J. Sci. Am. 4, 385-389 (1998).
33. G. A. Freyer, D. A. Palmer, Y. Yu, R. C. Miller and T. K. Pandita, Neoplastic transformation of mouse C3H10T1/2 cells following exposure to neutrons does not involve mutation of ras gene as analyzed by SSCP and cycle sequencing. Mutat. Res. 357, 237-244 (1996).
34. J. A. Metcalf, J. Parkhill, L. Cambell, M. Stacey, P. Biggs, P. J. Byrd and M. R. Taylor, Accelerated telomere shortening in ataxia telangiectasia. Nat. Genet. 13, 350-353 (1996).
35. H. Vaziri, M. D. West, R. C. Allsopp, T. S. Davison, Y. S. Wu, C. H. Arrowsmith, G. G. Poirier and S. Benchimol, ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. EMBO J. 16, 6018-6033 (1997).
36. P. W. Greenwell, S. L. Kronmal, S. E. Porter, J. Gassenhuber, B. Obermaier and T. D. Petes, TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 82, 823-829 (1995).
37. K. L. Hari, A. Santerre, J. J. Sekelsky, K. S. McKim, J. B. Boyd and R. S. Hawley, The mei-41 gene of D. melanogaster is a structural and functional homologue of the human ataxia telangiectasia gene. Cell 82, 815-821 (1995).
38. B. van Steensel, A. Smogorzewska and T. de Lange, TRF2 protects human telomeres from end-to-end fusions. Cell 92, 401-413 (1998).
39. R. Berezney and D. S. Coffey, Identification of a nuclear protein matrix. Biochem. Biophys. Res. Commun. 60, 1410-1417 (1974).
40. T. de Lange, Human telomeres are attached to the nuclear matrix. EMBO J. 11, 717-724 (1992).
41. D. P. Gately, J. C. Hittle, G. K. T. Chan and T. J. Yen, Characterization of ATM expression, localization and associated DNA-dependent protein kinase activity. Mol. Biol. Cell. 9, 2361-2374 (1998).
42. J. Karlseder, D. Broccoli, Y. Dai, S. Hardy and T. de Lange, p53-and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science 283, 1321-1325 (1999).
43. M. N. Cornforth and J. S. Bedford, On the nature of a defect in cells from individuals with ataxia-telangiectasia. Science 227, 1589-1591 (1985).
44. T. K. Pandita and W. N. Hittelman, Initial chromosome damage but not DNA damage is greater in ataxia telangiectasia cells. Radiat. Res. 130, 94-103 (1992).