The Contribution of the Exosite Residues of Plasminogen Activator Inhibitor-1 to Proteinase Inhibition

Journal of Biological Chemistry

Volumn 279, Issue 5, 2004, Pages 3643-3650

  Ibarra, Catherine A ^a   Blouse, Grant E ^a,b   Christian, Thomas D ^a   Shore, Joseph D ^a,b  

^a HENRY FORD HEALTH SCIENCES CENTER   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; FLUOROMETERS; QUENCHING;

PLASMINOGEN ACTIVATORS;

BIOCHEMISTRY;

ALANINE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEINASE INHIBITOR; RECOMBINANT PROTEIN; SERINE PROTEINASE INHIBITOR; TRYPSIN; UROKINASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; ANIMAL CELL; ARTICLE; BINDING SITE; CATTLE; CHEMICAL MODEL; CHEMISTRY; COMPLEX FORMATION; CRYSTAL STRUCTURE; DOSE RESPONSE; ENZYME INHIBITION; ENZYME METABOLISM; FIBRINOLYSIS; GENE MUTATION; GENETIC ANALYSIS; KINETICS; METABOLISM; MICHAELIS CONSTANT; MOLECULAR GENETICS; MOLECULAR INTERACTION; MUTATION; NONHUMAN; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN SECONDARY STRUCTURE; RECEPTOR BINDING; RESIDUE ANALYSIS; SPECTROFLUOROMETRY; SPECTROPHOTOMETRY; SWINE; THERMODYNAMICS;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; KINETICS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEASE INHIBITORS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SERPINS; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY; SWINE; THERMODYNAMICS; TRYPSIN;

ANIMALIA; BOS TAURUS; SUS SCROFA;

EID: 0942276359     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310601200     Document Type: Article

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