The distal hinge of the reactive site loop and its proximity: A target to modulate plasminogen activator inhibitor-1 activity

Journal of Biological Chemistry

Volumn 276, Issue 48, 2001, Pages 44912-44918

  Bijnens, Ann Pascale ^a   Gils, Ann ^a   Stassen, Jan M ^b   Komissarov, Andrey A ^c   Knockaert, Isabelle ^a   Brouwers, Els ^a   Shore, Joseph D ^c   Declerck, Paul J ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^c Henry Ford Health Science Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; MONOCLONAL ANTIBODIES; SURFACE PLASMON RESONANCE;

REACTIVE SITE LOOP;

PHYSIOLOGY;

ALANINE; ARGININE; ASPARTIC ACID; EPITOPE; GLUTAMIC ACID; HISTONE; LYSINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MA 42A2F6; MONOCLONAL ANTIBODY MA 44E4; MONOCLONAL ANTIBODY MA 56A7C10; PLASMINOGEN ACTIVATOR INHIBITOR 1; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; DNA; HISTIDINE;

ARTICLE; CROSS REACTION; FIBRINOLYSIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN TARGETING; SEQUENCE ALIGNMENT; SURFACE PLASMON RESONANCE; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; KINETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; RAT; SEQUENCE HOMOLOGY; SWINE; TIME;

ALANINE; AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES, MONOCLONAL; ARGININE; ASPARTIC ACID; BINDING SITES; DNA; EPITOPES; GLUTAMIC ACID; HISTIDINE; HUMAN; KINETICS; LYSINE; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; SURFACE PLASMON RESONANCE; SWINE; TIME FACTORS;

EID: 0035977012     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103077200     Document Type: Article

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