A concerted structural transition in the plasminogen activator inhibitor-1 mechanism of inhibition

Biochemistry

Volumn 41, Issue 40, 2002, Pages 11997-12009

  Blouse, Grant E ^a,b   Perron, Michel J ^a   Thompson, Jannah H ^a   Day, Duane E ^a   Link, Chad A ^a   Shore, Joseph D ^a,b  

^a HENRY FORD HEALTH SCIENCES CENTER   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

STRUCTURAL TRANSITION;

ENZYME INHIBITION; FLUORESCENCE; REACTION KINETICS; TISSUE;

ENZYMES;

PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEINASE; SERINE PROTEINASE INHIBITOR; TRYPTOPHAN; UROKINASE;

AMINO ACID SUBSTITUTION; ARTICLE; BETA SHEET; CHEMICAL REACTION KINETICS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; COVALENT BOND; FLUORESCENCE; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING;

BINDING SITES; CIRCULAR DICHROISM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; KINETICS; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN CONFORMATION; SPECTROMETRY, FLUORESCENCE; TISSUE PLASMINOGEN ACTIVATOR; TRYPTOPHAN; URINARY PLASMINOGEN ACTIVATOR;

INSERTION SEQUENCES;

EID: 0037044304     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi025967p     Document Type: Article

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