Mechanisms of conversion of plasminogen activator inhibitor 1 from a suicide inhibitor to a substrate by monoclonal antibodies

Journal of Biological Chemistry

Volumn 277, Issue 46, 2002, Pages 43858-43865

  Komissarov, Andrey A ^a   Declerck, Paul J ^b   Shore, Joseph D ^a  

^a HENRY FORD HEALTH SYSTEM   (United States)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLATION; MOLECULES; MONOCLONAL ANTIBODIES; SUBSTRATES; TISSUE;

PLASMINOGEN ACTIVATORS;

BIOCHEMISTRY;

MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 33H1F7; MONOCLONAL ANTIBODY 55F4C12; MONOCLONAL ANTIBODY 8H9D4; PLASMINOGEN ACTIVATOR INHIBITOR 1; SERINE; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG; UROKINASE;

ARTICLE; CHEMICAL MODIFICATION; COMPLEX FORMATION; DEACYLATION; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; MOLECULAR INTERACTION; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, MONOCLONAL; BINDING SITES; CHROMATOGRAPHY, GEL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; KINETICS; MICE; MODELS, CHEMICAL; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN BINDING; SERINE; SUBCELLULAR FRACTIONS; SUBSTRATE SPECIFICITY; TISSUE PLASMINOGEN ACTIVATOR; URINARY PLASMINOGEN ACTIVATOR;

INSERTION SEQUENCES;

EID: 0346461093     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M204110200     Document Type: Article

References (52)

1. Hekman, C. M., and Loskutoff, D. J. (1985) J. Biol. Chem. 260, 11581-11587
2. Gettins, P., Patston, P. A., and Schapira, M. (1993) Bioessays 15, 461-467
3. van Meijer, M., and Pannekoek, H. (1995) Fibrinolysis 263-276
4. Silverman, G. A., Bird, P. I., Carrell, R. W., Church, F. C., Coughlin, P. B., Gettins, P. G., Irving, J. A., Lomas, D. A., Luke, C. J., Moyer, R. W., Pemberton, P. A., Remold-O'Dannell, E., Salvesen, G. S., Travis, J., and Whisstock, J. C. (2001) J. Biol. Chem. 276, 33293-33296
5. van Mourik, J. A., Lawrence, D. A., and Loskutoff, D. J. (1984) J. Biol. Chem. 259, 14914-14921
6. Carrell, R. W., Evans, D. L., and Stein, P. E. (1991) Nature 353, 576-578
7. Gettins, P., Patston, P. A., and Schapira, M. (1992) Hematol. Oncol. Clin. N. Am. 6, 1393-1408
8. Wiman, B. (1995) Thromb. Haemostasis 74, 71-76
9. Rando, R. R. (1974) Science 185, 320-324
10. Walsh, C., Cromartie, T., Marcotte, P., and Spencer, R. (1978) Methods Enzymol. 53, 437-448
11. Lawrence, D. A., Ginsburg, D., Day, D. E., Berkenpas, M. B., Verhamme, I. M., Kvassman, J. O., and Shore, J. D. (1995) J. Biol. Chem. 270, 25309-25312
12. Wilczynska, M., Fa, M., Ohlsson, P. I., and Ny, T. (1995) J. Biol. Chem. 270, 29652-29655
13. Egelund, R., Rodenburg, K. W., Andreasen, P. A., Rasmussen, M. S., Guldberg, R. E., and Petersen, T. E. (1998) Biochemistry 37, 6375-6379
14. Lawrence, D. A., Strandberg, L., Ericson, J., and Ny, T. (1990) J. Biol. Chem. 265, 20293-20301
15. Loebermann, H., Tokuoka, R., Deisenhofer, J., and Huber, R. (1984) J. Mol. Biol. 177, 531-557
16. Mottonen, J., Strand, A., Symersky, J., Sweet, R. M., Danley, D. E., Geoghegan, K. F., Gerard, R. D., and Goldsmith, E. J. (1992) Nature 355, 270-273
17. Stratikos, E., and Gettins, P. G. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 453-458
18. Wilczynska, M., Fa, M., Karolin, J., Ohlsson, P. I., Johansson, L. B., and Ny, T. (1997) Nat. Struct. Biol. 4, 354-357
19. Huntington, J. A., Read, R. J., and Carrell, R. W. (2000) Nature 407, 923-926
20. Nar, H., Bauer, M., Stassen, J. M., Lang, D., Gils, A., and Declerck, P. J. (2000) J. Mol. Biol. 297, 683-695
21. Sharp, A. M., Stein, P. E., Pannu, N. S., Carrell, R. W., Berkenpas, M. B., Ginsburg, D., Lawrence, D. A., and Read, R. J. (1999) Struct. Fold. Des. 7, 111-118
22. Stout, T. J., Graham, H., Buckley, D. I., and Matthews, D. J. (2000) Biochemistry 39, 8460-8469
23. Aertgeerts, K., De Bondt, H. L., De Ranter, C., and Declerck, P. J. (1995) Proteins 23, 118-121
24. Patston, P. A., Gettins, P., Beechem, J., and Schapira, M. (1991) Biochemistry 30, 8876-8882
25. Kvassman, J. O., Verhamme, I., and Shore, J. D. (1998) Biochemistry 37, 15491-15502
26. Lawrence, D. A., Olson, S. T., Muhammad, S., Day, D. E., Kvassman, J. O., Ginsburg, D., and Shore, J. D. (2000) J. Biol. Chem. 275, 5839-5844
27. Charlton, P. A., Faint, R. W., Bent, F., Bryans, J., Chicarelli-Robinson, I., Mackie, I., Machin, S., and Bevan, P. (1996) Thromb. Haemostasis 75, 808-815
28. Bjorquist, P., Ehnebom, J., Inghardt, T., Hansson, L., Lindberg, M., Linschoten, M., Stromqvist, M., and Deinum, J. (1998) Biochemistry 37, 1227-1234
29. Folkes, A., Roe, M. B., Sohal, S., Golec, J., Faint, R., Brooks, T., and Charlton, P. (2001) Bioorg. Med. Chem. Lett. 11, 2589-2592
30. Folkes, A., Brown, S. D., Canne, L. E., Chan, J., Engelhardt, E., Epshteyn, S., Faint, R., Golec, J., Hanel, A., Kearney, P., Leahy, J. W., Mac, M., Matthews, D., Prisbylla, M. P., Sanderson, J., Simon, R. J., Tesfai, Z., Vicker, N., Wang, S., Webb, R. R., and Charlton, P. (2002) Bioorg. Med. Chem. Lett. 12, 1063-1066
31. Keijer, J., Linders, M., van Zonneveld, A. J., Ehrlich, H. J., de Boer, J. P., and Pannekoek, H. (1991) Blood 78, 401-409
32. Bijnens, A. P., Gils, A., Stassen, J. M., Komissarov, A. A., Knockaert, I., Brouwers, E., Shore, J. D., and Declerck, P. J. (2001) J. Biol. Chem. 276, 44912-44918
33. Bijnens, A. P., Gils, A., Knockaert, I., Stassen, J. M., and Declerck, P. J. (2000) J. Biol. Chem. 275, 6375-6380
34. van Zonneveld, A. J., van den Berg, B. M., van Meijer, M., and Pannekoek, H. (1995) Gene (Amst.) 167, 49-52
35. Bjorquist, P., Ehnebom, J., Inghardt, T., and Deinum, J. (1997) Biochim. Biophys. Acta 1341, 87-98
36. Petersen, H. H., Hansen, M., Schousboe, S. L., and Andreasen, P. A. (2001) Eur. J. Biochem. 268, 4430-4439
37. Wind, T., Jensen, M. A., and Andreasen, P. A. (2001) Eur. J. Biochem. 268, 1095-1106
38. Verhamme, I., Kvassman, J. O., Day, D., Debrock, S., Vleugels, N., Declerck, P. J., and Shore, J. D. (1999) J. Biol. Chem. 274, 17511-17517
39. Bijnens, A. P., Ngo, T. H., Gils, A., Dewaele, J., Knockaert, I., Stassen, J. M., and Declerck, P. J. (2001) Thromb. Haemostasis 85, 866-874
40. Debrock, S., and Declerck, P. J. (1997) Biochim. Biophys. Acta 1337, 257-266
41. Ngo, T. H., Debrock, S., and Declerck, P. J. (1997) FEBS Lett. 416, 373-376
42. Debrock, S., and Declerck, P. J. (1998) Thromb. Haemostasis 79, 597-601
43. Shore, J. D., Day, D. E., Francis-Chmura, A. M., Verhamme, I., Kvassman, J., Lawrence, D. A., and Ginsburg, D. (1995) J. Biol. Chem. 270, 5395-5398
44. Vaughan, D. E., Declerck, P. J., Reilly, T. M., Park, K., Collen, D., and Fasman, G. D. (1993) Biochim. Biophys. Acta 1202, 221-229
45. Kvassman, J. O., and Shore, J. D. (1995) Fibrinolysis 9, 215-221
46. Chaillan-Huntington, C. E., Gettins, P. G. W., Huntington, J. A., and Patston, P. A. (1997) Biochemistry 36, 9562-9570
47. Evans, S. A., Olson, S. T., and Shore, J. D. (1982) J. Biol. Chem. 257, 3014-3017
48. Olson, S. T., and Shore, J. D. (1982) J. Biol. Chem. 257, 14891-14895
49. Lawrence, D. A., Olson, S. T., Palaniappan, S., and Ginsburg, D. (1994) J. Biol. Chem. 269, 27657-27662
50. Rajpal, A., Taylor, M. G., and Kirsch, J. F. (1998) Protein Sci. 7, 1868-1874
51. Madison, E. L., Goldsmith, E. J., Gerard, R. D., Gething, M. J., and Sambrook, J. F. (1989) Nature 339, 721-724
52. van Meijer, M., Roelofs, Y., Neels, J., Horrevoets, A. J., van Zonneveld, A. J., and Pannekoek, H. (1996) J. Biol. Chem. 271, 7423-7428