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Volumn 14, Issue 1, 2004, Pages 71-77

Can mouse models for brain tumors inform treatment in pediatric patients?

Author keywords

Mouse models of cancer; Pediatric brain tumors; Targeted therapies

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAS PROTEIN; TEMOZOLOMIDE; TIPIFARNIB;

EID: 0842329751     PISSN: 1044579X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semcancer.2003.11.008     Document Type: Article
Times cited : (2)

References (46)
  • 2
    • 0036655059 scopus 로고    scopus 로고
    • Medulloblastoma: A problem of developmental biology
    • Rubin J.B., Rowitch D.H. Medulloblastoma: a problem of developmental biology. Cancer Cell. 2(1):2002;7-8.
    • (2002) Cancer Cell , vol.2 , Issue.1 , pp. 7-8
    • Rubin, J.B.1    Rowitch, D.H.2
  • 3
    • 0036192918 scopus 로고    scopus 로고
    • Kleihues P, Louis DN, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC, et al. The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol 2002;61(3):215-25 [discussion, 26-9].
    • Kleihues P, Louis DN, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC, et al. The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol 2002;61(3):215-25 [discussion, 26-9].
  • 4
    • 0024372477 scopus 로고
    • The effectiveness of chemotherapy for treatment of high grade astrocytoma in children, results of a randomized trial. A report from the Childrens Cancer Study Group
    • Sposto R., Ertel I.J., Jenkin R.D., Boesel C.P., Venes J.L., Ortega J.A.et al. The effectiveness of chemotherapy for treatment of high grade astrocytoma in children, results of a randomized trial. A report from the Childrens Cancer Study Group. J. Neurooncol. 7:1989;165-177.
    • (1989) J. Neurooncol. , vol.7 , pp. 165-177
    • Sposto, R.1    Ertel, I.J.2    Jenkin, R.D.3    Boesel, C.P.4    Venes, J.L.5    Ortega, J.A.6
  • 5
    • 0028850852 scopus 로고
    • Randomized Phase III trial in childhood high-grade astrocytoma comparing vincristine, lomustine and prednisone with the eight-drugs-in-one-day regimen
    • Finlay J.L., Boyett J.M., Yates A.J., Wisoff J.H., Milstein J.M., Geyer J.R.et al. Randomized Phase III trial in childhood high-grade astrocytoma comparing vincristine, lomustine and prednisone with the eight-drugs-in-one-day regimen. J. Clin. Oncol. 13:1995;112-123.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 112-123
    • Finlay, J.L.1    Boyett, J.M.2    Yates, A.J.3    Wisoff, J.H.4    Milstein, J.M.5    Geyer, J.R.6
  • 7
    • 0032518577 scopus 로고    scopus 로고
    • Pediatric brain stem gliomas: A review
    • Freeman C.Ra.J.P.F. Pediatric brain stem gliomas: a review. Int J Radiat Oncol Biol. 40(2):1998;265-271.
    • (1998) Int J Radiat Oncol Biol , vol.40 , Issue.2 , pp. 265-271
    • Freeman, C.Ra.J.P.F.1
  • 8
    • 0030071683 scopus 로고    scopus 로고
    • High-grade astrocytomas in children: Radiologically complete resection is associated with an excellent long-term prognosis
    • Campbell J.W., Pollack I.F., Martinez A.J., Shultz B. High-grade astrocytomas in children: radiologically complete resection is associated with an excellent long-term prognosis. Neurosurgery. 38(2):1996;258-264.
    • (1996) Neurosurgery , vol.38 , Issue.2 , pp. 258-264
    • Campbell, J.W.1    Pollack, I.F.2    Martinez, A.J.3    Shultz, B.4
  • 9
    • 0037034253 scopus 로고    scopus 로고
    • Pollack IF, Woods J, Burnham J, Holmes EJ, Hamilton RL, Yates AJ, et al., the Children's Cancer Group. Expression of p53 and Prognosis in Children with Malignant Gliomas. N Engl J Med 2002;346(6):420-6.
    • Pollack IF, Woods J, Burnham J, Holmes EJ, Hamilton RL, Yates AJ, et al., the Children's Cancer Group. Expression of p53 and Prognosis in Children with Malignant Gliomas. N Engl J Med 2002;346(6):420-6.
  • 10
    • 0035887141 scopus 로고    scopus 로고
    • Pollack IF, Burnham J, Holmes EJ, Hamilton RL, Yates AJ, Finlay JL, et al., the Children's Cancer Group. Age and TP53 mutation frequency in childhood malignant gliomas: results in a multi-institutional cohort. Cancer Res 2001;61:7404-7.
    • Pollack IF, Burnham J, Holmes EJ, Hamilton RL, Yates AJ, Finlay JL, et al., the Children's Cancer Group. Age and TP53 mutation frequency in childhood malignant gliomas: results in a multi-institutional cohort. Cancer Res 2001;61:7404-7.
  • 11
    • 0032781105 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression and gene amplification in high grade non-brainstem gliomas of childhood
    • Bredel M.P., Ian F., Hamilton R.L., James C.D. Epidermal growth factor receptor expression and gene amplification in high grade non-brainstem gliomas of childhood. Clin. Cancer Res. 5:1999;1786-1792.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1786-1792
    • Bredel, M.P.1    Ian, F.2    Hamilton, R.L.3    James, C.D.4
  • 12
    • 0033398991 scopus 로고    scopus 로고
    • Analysis of oncogene and tumor suppressor gene alterarations in pediatric malignant astrocytomas reveals reduced survival for patients with PTEN mutations
    • Raffel C.F.L., O'Fallon J.R., Atherton-Skaff P., Perry A., Jenkins R.B., James C.D. Analysis of oncogene and tumor suppressor gene alterarations in pediatric malignant astrocytomas reveals reduced survival for patients with PTEN mutations. Clin. Cancer Res. 5:1999;4085-4090.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 4085-4090
    • Raffel, C.F.L.1    O'Fallon, J.R.2    Atherton-Skaff, P.3    Perry, A.4    Jenkins, R.B.5    James, C.D.6
  • 13
    • 0032971251 scopus 로고    scopus 로고
    • Mutational analysis of the PTEN gene in gliomas: Molecular and pathological correlations
    • Zhou X.P., Li Y.J., Hoang-Xuan K., Laurent-Puig P., Mokhtari K., Longy M.et al. Mutational analysis of the PTEN gene in gliomas: molecular and pathological correlations. Int J Cancer. 84:1999;150-154.
    • (1999) Int J Cancer , vol.84 , pp. 150-154
    • Zhou, X.P.1    Li, Y.J.2    Hoang-Xuan, K.3    Laurent-Puig, P.4    Mokhtari, K.5    Longy, M.6
  • 14
    • 0025282206 scopus 로고
    • Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance
    • Maxwell M.N.S.P., Wolfe H.J. Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance. J. Clin. Invest. 86:1990;131-140.
    • (1990) J. Clin. Invest. , vol.86 , pp. 131-140
    • Maxwell, M.N.S.P.1    Wolfe, H.J.2
  • 15
    • 0027952893 scopus 로고
    • Activated platelet-derived growth factor autocrine pathway drives the transformed phenotype of a human glioblastoma cell line
    • Vassbotn F.O.A., Langeland N., Holmsen H., Westermark B., Heldin C.-H., Nister M. Activated platelet-derived growth factor autocrine pathway drives the transformed phenotype of a human glioblastoma cell line. J. Cell Physiol. 158:1994;381-389.
    • (1994) J. Cell Physiol. , vol.158 , pp. 381-389
    • Vassbotn, F.O.A.1    Langeland, N.2    Holmsen, H.3    Westermark, B.4    Heldin, C.-H.5    Nister, M.6
  • 16
    • 0026352767 scopus 로고
    • Co-expression of platelet-derived growth factor (PDGF) B chain and PDGF B type receptor in human gliomas
    • Mauro A.B.A., Turco E., Schiffer D. Co-expression of platelet-derived growth factor (PDGF) B chain and PDGF B type receptor in human gliomas. Child Nerv Syst. 7:1991;432-436.
    • (1991) Child Nerv Syst. , vol.7 , pp. 432-436
    • Mauro, A.B.A.1    Turco, E.2    Schiffer, D.3
  • 17
    • 0032927688 scopus 로고    scopus 로고
    • The p21-Ras signal transduction pathway and growth regulation in human high-grade gliomas
    • Bredel M.P., Ian F. The p21-Ras signal transduction pathway and growth regulation in human high-grade gliomas. Brain Res. Rev. 29(2/3):1999;232-249.
    • (1999) Brain Res. Rev. , vol.29 , Issue.2-3 , pp. 232-249
    • Bredel, M.P.1    Ian, F.2
  • 18
    • 0036499085 scopus 로고    scopus 로고
    • Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide
    • Stupp R.D.P.Y., Ostermann Kraljevic S., Pica A., Maillard I., Maeder P., Meuli R.et al. Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide. J. Clin. Onocol. 20(5):2002;1375-1382.
    • (2002) J. Clin. Onocol. , vol.20 , Issue.5 , pp. 1375-1382
    • Stupp, R.D.P.Y.1    Ostermann Kraljevic, S.2    Pica, A.3    Maillard, I.4    Maeder, P.5    Meuli, R.6
  • 19
    • 0037842147 scopus 로고    scopus 로고
    • Phase III study comparing three cycles of infusional carmustine and cisplatin followed by radiation therapy with radiation therapy and concurrent carmustine in patients with newly diagnosed supratentorial glioblastoma multiforme, Eastern Cooperative Oncology 2394
    • Grossman S.O.N.A., Grunnet M., Mehta M., Pearlman J.L., Wagner H., Gilbert M.et al. Phase III study comparing three cycles of infusional carmustine and cisplatin followed by radiation therapy with radiation therapy and concurrent carmustine in patients with newly diagnosed supratentorial glioblastoma multiforme, Eastern Cooperative Oncology 2394. J. Clin. Oncol. 21(8):2003;1485-1491.
    • (2003) J. Clin. Oncol. , vol.21 , Issue.8 , pp. 1485-1491
    • Grossman, S.O.N.A.1    Grunnet, M.2    Mehta, M.3    Pearlman, J.L.4    Wagner, H.5    Gilbert, M.6
  • 22
    • 0031033221 scopus 로고    scopus 로고
    • Altered myeloid development and acute leukemia in transgenic mice expressing PML-RAR alpha under control of cathepsin G regulatory sequences
    • Grisolano J.L., Wesselschmidt R.L., Pelicci P.G., Ley T.J. Altered myeloid development and acute leukemia in transgenic mice expressing PML-RAR alpha under control of cathepsin G regulatory sequences. Blood. 89(2):1997;376-387.
    • (1997) Blood , vol.89 , Issue.2 , pp. 376-387
    • Grisolano, J.L.1    Wesselschmidt, R.L.2    Pelicci, P.G.3    Ley, T.J.4
  • 23
    • 0035525787 scopus 로고    scopus 로고
    • Establishment of a murine model for therapy-treated chronic myelogenous leukemia using the tyrosine kinase inhibitor STI571
    • Wolff N.C., Ilaria R.L. Jr. Establishment of a murine model for therapy-treated chronic myelogenous leukemia using the tyrosine kinase inhibitor STI571. Blood. 98(9):2001;2808-2816.
    • (2001) Blood , vol.98 , Issue.9 , pp. 2808-2816
    • Wolff, N.C.1    Ilaria, R.L.Jr.2
  • 25
    • 0035328722 scopus 로고    scopus 로고
    • Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas
    • Ding H., Roncari L., Shannon P., Wu X., Lau N., Karaskova J.et al. Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas. Cancer Res. 61(9):2001;3826-3836.
    • (2001) Cancer Res , vol.61 , Issue.9 , pp. 3826-3836
    • Ding, H.1    Roncari, L.2    Shannon, P.3    Wu, X.4    Lau, N.5    Karaskova, J.6
  • 26
    • 0036490954 scopus 로고    scopus 로고
    • Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation
    • Xiao A., Wu H., Pandolfi P.P., Louis D.N., Van Dyke T. Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation. Cancer Cell. 1(2):2002;157-168.
    • (2002) Cancer Cell , vol.1 , Issue.2 , pp. 157-168
    • Xiao, A.1    Wu, H.2    Pandolfi, P.P.3    Louis, D.N.4    Van Dyke, T.5
  • 27
    • 0037382205 scopus 로고    scopus 로고
    • Genetic determinants of malignancy in a mouse model for oligodendroglioma
    • Weiss W.A., Burns M.J., Hackett C., Aldape K., Hill J.R., Kuriyama H.et al. Genetic determinants of malignancy in a mouse model for oligodendroglioma. Cancer Res. 63(7):2003;1589-1595.
    • (2003) Cancer Res , vol.63 , Issue.7 , pp. 1589-1595
    • Weiss, W.A.1    Burns, M.J.2    Hackett, C.3    Aldape, K.4    Hill, J.R.5    Kuriyama, H.6
  • 28
    • 0032418416 scopus 로고    scopus 로고
    • A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice
    • Holland E.C., Hively W.P., DePinho R.A., Varmus H.E. A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes Dev. 12(23):1998;3675-3685.
    • (1998) Genes Dev , vol.12 , Issue.23 , pp. 3675-3685
    • Holland, E.C.1    Hively, W.P.2    Depinho, R.A.3    Varmus, H.E.4
  • 29
    • 0034020459 scopus 로고    scopus 로고
    • Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
    • Holland E.C., Celestino J., Dai C., Schaefer L., Sawaya R.E., Fuller G.N. Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat Genet. 25(1):2000;55-57.
    • (2000) Nat Genet , vol.25 , Issue.1 , pp. 55-57
    • Holland, E.C.1    Celestino, J.2    Dai, C.3    Schaefer, L.4    Sawaya, R.E.5    Fuller, G.N.6
  • 30
    • 0037424347 scopus 로고    scopus 로고
    • Astroglial c-Myc overexpression predisposes mice to primary malignant gliomas
    • Jensen N.A., Pedersen K.M., Lihme F., Rask L., Nielsen J.V., Rasmussen T.E.et al. Astroglial c-Myc overexpression predisposes mice to primary malignant gliomas. J Biol Chem. 278(10):2003;8300-8308.
    • (2003) J Biol Chem , vol.278 , Issue.10 , pp. 8300-8308
    • Jensen, N.A.1    Pedersen, K.M.2    Lihme, F.3    Rask, L.4    Nielsen, J.V.5    Rasmussen, T.E.6
  • 31
    • 0033812187 scopus 로고    scopus 로고
    • Nf1, Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects
    • Reilly K.M., Loisel D.A., Bronson R.T., McLaughlin M.E., Jacks T. Nf1, Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects. Nat Genet. 26(1):2000;109-113.
    • (2000) Nat Genet , vol.26 , Issue.1 , pp. 109-113
    • Reilly, K.M.1    Loisel, D.A.2    Bronson, R.T.3    McLaughlin, M.E.4    Jacks, T.5
  • 32
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies S.P., Reddy H., Caivano M., Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J. 351(Pt 1):2000;95-105.
    • (2000) Biochem J , vol.351 , Issue.PT 1 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 33
    • 0037392942 scopus 로고    scopus 로고
    • The specificities of protein kinase inhibitors: An update
    • Bain J., McLauchlan H., Elliott M., Cohen P. The specificities of protein kinase inhibitors: an update. Biochem J. 371(Pt 1):2003;199-204.
    • (2003) Biochem J , vol.371 , Issue.PT 1 , pp. 199-204
    • Bain, J.1    McLauchlan, H.2    Elliott, M.3    Cohen, P.4
  • 34
  • 35
    • 0021281324 scopus 로고
    • Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
    • Downward J., Yarden Y., Mayes E., Scrace G., Totty N., Stockwell P.et al. Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. Nature. 307(5951):1984;521-527.
    • (1984) Nature , vol.307 , Issue.5951 , pp. 521-527
    • Downward, J.1    Yarden, Y.2    Mayes, E.3    Scrace, G.4    Totty, N.5    Stockwell, P.6
  • 37
    • 0034282723 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor tyrosine kinase fails to suppress adenoma formation in ApcMin mice but induces duodenal injury
    • Ritland S.R., Gendler S.J., Burgart L.J., Fry D.W., Nelson J.M., Bridges A.J.et al. Inhibition of epidermal growth factor receptor tyrosine kinase fails to suppress adenoma formation in ApcMin mice but induces duodenal injury. Cancer Res. 60(17):2000;4678-4681.
    • (2000) Cancer Res , vol.60 , Issue.17 , pp. 4678-4681
    • Ritland, S.R.1    Gendler, S.J.2    Burgart, L.J.3    Fry, D.W.4    Nelson, J.M.5    Bridges, A.J.6
  • 38
    • 0037022292 scopus 로고    scopus 로고
    • Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis
    • Roberts R.B., Min L., Washington M.K., Olsen S.J., Settle S.H., Coffey R.J.et al. Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis. Proc Natl Acad Sci USA. 99(3):2002;1521-1526.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.3 , pp. 1521-1526
    • Roberts, R.B.1    Min, L.2    Washington, M.K.3    Olsen, S.J.4    Settle, S.H.5    Coffey, R.J.6
  • 40
    • 0037143445 scopus 로고    scopus 로고
    • Chemical genetic blockade of transformation reveals dependence on aberrant oncogenic signaling
    • Fan Q.W., Zhang C., Shokat K.M., Weiss W.A. Chemical genetic blockade of transformation reveals dependence on aberrant oncogenic signaling. Curr Biol. 12(16):2002;1386-1394.
    • (2002) Curr Biol , vol.12 , Issue.16 , pp. 1386-1394
    • Fan, Q.W.1    Zhang, C.2    Shokat, K.M.3    Weiss, W.A.4
  • 41
    • 0034629485 scopus 로고    scopus 로고
    • Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity
    • Busse D., Doughty R.S., Ramsey T.T., Russell W.E., Price J.O., Flanagan W.M.et al. Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity. J Biol Chem. 275(10):2000;6987-6995.
    • (2000) J Biol Chem , vol.275 , Issue.10 , pp. 6987-6995
    • Busse, D.1    Doughty, R.S.2    Ramsey, T.T.3    Russell, W.E.4    Price, J.O.5    Flanagan, W.M.6
  • 42
    • 0034682721 scopus 로고    scopus 로고
    • Cellular senescence: Mitotic clock or culture shock?
    • Sherr C.J., DePinho R.A. Cellular senescence: mitotic clock or culture shock? Cell. 102(4):2000;407-410.
    • (2000) Cell , vol.102 , Issue.4 , pp. 407-410
    • Sherr, C.J.1    Depinho, R.A.2
  • 44
    • 0029921232 scopus 로고    scopus 로고
    • The farnesyltransferase inhibitor FTI-277 radiosensitizes H-ras-transformed rat embryo fibroblasts
    • Bernhard E.J., Kao G., Cox A.D., Sebti S.M., Hamilton A.D., Muschel R.J.et al. The farnesyltransferase inhibitor FTI-277 radiosensitizes H-ras-transformed rat embryo fibroblasts. Cancer Res. 56(8):1996;1727-1730.
    • (1996) Cancer Res , vol.56 , Issue.8 , pp. 1727-1730
    • Bernhard, E.J.1    Kao, G.2    Cox, A.D.3    Sebti, S.M.4    Hamilton, A.D.5    Muschel, R.J.6
  • 45
    • 0032522849 scopus 로고    scopus 로고
    • Inhibiting Ras prenylation increases the radiosensitivity of human tumor cell lines with activating mutations of ras oncogenes
    • Bernhard E.J., McKenna W.G., Hamilton A.D., Sebti S.M., Qian Y., Wu J.M.et al. Inhibiting Ras prenylation increases the radiosensitivity of human tumor cell lines with activating mutations of ras oncogenes. Cancer Res. 58(8):1998;1754-1761.
    • (1998) Cancer Res , vol.58 , Issue.8 , pp. 1754-1761
    • Bernhard, E.J.1    McKenna, W.G.2    Hamilton, A.D.3    Sebti, S.M.4    Qian, Y.5    Wu, J.M.6
  • 46
    • 0036643779 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation
    • Delmas C., Heliez C., Cohen-Jonathan E., End D., Bonnet J., Favre G.et al. Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation. Int J Cancer. 100(1):2002;43-48.
    • (2002) Int J Cancer , vol.100 , Issue.1 , pp. 43-48
    • Delmas, C.1    Heliez, C.2    Cohen-Jonathan, E.3    End, D.4    Bonnet, J.5    Favre, G.6


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