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Volumn 89, Issue 2, 1997, Pages 376-387

Altered myeloid development and acute leukemia in transgenic mice expressing PML-RARα under control of cathepsin G regulatory sequences

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN G; RETINOIC ACID RECEPTOR;

EID: 0031033221     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.2.376     Document Type: Article
Times cited : (330)

References (50)
  • 1
    • 0017362792 scopus 로고
    • 15/17 Translocation, a consistent chromosomal change in acute promyelocytic leukemia
    • Rowley JD, Colomb HM, Dougherty C: 15/17 Translocation, a consistent chromosomal change in acute promyelocytic leukemia. Lancet 1:549, 1977
    • (1977) Lancet , vol.1 , pp. 549
    • Rowley, J.D.1    Colomb, H.M.2    Dougherty, C.3
  • 3
    • 0025043959 scopus 로고
    • The t(15; 17) translocation of acute promyelocytic leukemia fuses the retinoic acid receptor α gene to a novel transcribed locus
    • de The H, Chomienne C, Lanotte M, Degos L, Dejean A: The t(15; 17) translocation of acute promyelocytic leukemia fuses the retinoic acid receptor α gene to a novel transcribed locus. Nature 347:558, 1990
    • (1990) Nature , vol.347 , pp. 558
    • De The, H.1    Chomienne, C.2    Lanotte, M.3    Degos, L.4    Dejean, A.5
  • 4
    • 0025780876 scopus 로고
    • Chromosomal translocation t(15; 17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML
    • Kakizuka A, Miller WH Jr, Umesono K, Warrell RP Jr, Frankel SR, Murty VVVS, Dmitrovsky E, Evans RM: Chromosomal translocation t(15; 17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML. Cell 66:663, 1991
    • (1991) Cell , vol.66 , pp. 663
    • Kakizuka, A.1    Miller Jr., W.H.2    Umesono, K.3    Warrell Jr., R.P.4    Frankel, S.R.5    Murty, V.6    Dmitrovsky, E.7    Evans, R.M.8
  • 5
    • 0025875679 scopus 로고
    • The PML-RARα fusion mRNa generated by the t(15; 17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
    • de The H, Lavau C, Marchio A, Chomienne C, Degos L, Dejean A: The PML-RARα fusion mRNA generated by the t(15; 17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell 66:675, 1991
    • (1991) Cell , vol.66 , pp. 675
    • De The, H.1    Lavau, C.2    Marchio, A.3    Chomienne, C.4    Degos, L.5    Dejean, A.6
  • 6
    • 0025917413 scopus 로고
    • Structure and origin of the acute promyelocytic leukemia myl/RARα cDNA and characterization of its retinoid-binding and transactivation properties
    • Pandolfi PP, Grignani F, Alcalay M, Mencarelli A, Biondi A, LoCoco F, Grignan F, Pelicci PG: Structure and origin of the acute promyelocytic leukemia myl/RARα cDNA and characterization of its retinoid-binding and transactivation properties. Oncogene 6:1285, 1991
    • (1991) Oncogene , vol.6 , pp. 1285
    • Pandolfi, P.P.1    Grignani, F.2    Alcalay, M.3    Mencarelli, A.4    Biondi, A.5    LoCoco, F.6    Grignan, F.7    Pelicci, P.G.8
  • 7
    • 0026326963 scopus 로고
    • Characterization of a zinc finger gene disrupted by the t(15; 17) in acute promyelocytic leukemia
    • Goddard AD, Borrow J, Freemont PS, Solomon E: Characterization of a zinc finger gene disrupted by the t(15; 17) in acute promyelocytic leukemia. Science 254:1371, 1991
    • (1991) Science , vol.254 , pp. 1371
    • Goddard, A.D.1    Borrow, J.2    Freemont, P.S.3    Solomon, E.4
  • 8
    • 0026583943 scopus 로고
    • Structure, localization and transcriptional properties of two classes of retinoic acid receptor α fusion proteins in acute promyelocytic leukemia (APL): Structural similarities with a new family of oncoproteins
    • Kastner P, Perez A, Lutz Y, Rochette-Egly C, Gaub M-P, Durand B, Lanotte M, Berger R, Chambon P: Structure, localization and transcriptional properties of two classes of retinoic acid receptor α fusion proteins in acute promyelocytic leukemia (APL): Structural similarities with a new family of oncoproteins. EMBO J 11:629, 1992
    • (1992) EMBO J , vol.11 , pp. 629
    • Kastner, P.1    Perez, A.2    Lutz, Y.3    Rochette-Egly, C.4    Gaub, M.-P.5    Durand, B.6    Lanotte, M.7    Berger, R.8    Chambon, P.9
  • 9
    • 0026502780 scopus 로고
    • Characterization of a fusion cDNa (RARα/myl) transcribed from the t(15; 17) translocation breakpoint in acute promyelocytic leukemia
    • Chang K-S, Stass SA, Chu D-T, Deaven LL, Trujillo JM, Freireich EJ: Characterization of a fusion cDNA (RARα/myl) transcribed from the t(15; 17) translocation breakpoint in acute promyelocytic leukemia. Mol Cell Biol 12:800, 1992
    • (1992) Mol Cell Biol , vol.12 , pp. 800
    • Chang, K.-S.1    Stass, S.A.2    Chu, D.-T.3    Deaven, L.L.4    Trujillo, J.M.5    Freireich, E.J.6
  • 12
    • 0028176437 scopus 로고
    • The PML-RARα gene product of the t(15; 17) translocation inhibits retinoic acid-induced granulocytic differentiation and mediated transactivation in human myeloid cells
    • Rousselot P, Hardas B, Patel A, Guidez F, Gaken J, Castaigne S, Dejean A, de The H, Degos L, Farzaneh F, Chomienne C: The PML-RARα gene product of the t(15; 17) translocation inhibits retinoic acid-induced granulocytic differentiation and mediated transactivation in human myeloid cells. Oncogene 9:545, 1994
    • (1994) Oncogene , vol.9 , pp. 545
    • Rousselot, P.1    Hardas, B.2    Patel, A.3    Guidez, F.4    Gaken, J.5    Castaigne, S.6    Dejean, A.7    De The, H.8    Degos, L.9    Farzaneh, F.10    Chomienne, C.11
  • 13
    • 0025271098 scopus 로고
    • Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-α)
    • Collins SJ, Robertson KA, Mueller L: Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-α). Mol Cell Biol 10:2154, 1990
    • (1990) Mol Cell Biol , vol.10 , pp. 2154
    • Collins, S.J.1    Robertson, K.A.2    Mueller, L.3
  • 14
    • 0027297095 scopus 로고
    • A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage
    • Tsai S, Collins SJ: A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage. Proc Natl Acad Sci USA 90:7153, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7153
    • Tsai, S.1    Collins, S.J.2
  • 15
    • 0028828122 scopus 로고
    • Overexpression of retinoic acid receptor a suppresses myeloid cell differentiation at the promyelocytic stage
    • Onodera M, Kunisada T, Nishikawa S, Sakiyama Y, Matsumoto S, Nishikawa S-I: Overexpression of retinoic acid receptor a suppresses myeloid cell differentiation at the promyelocytic stage. Oncogene 11:1291, 1995
    • (1995) Oncogene , vol.11 , pp. 1291
    • Onodera, M.1    Kunisada, T.2    Nishikawa, S.3    Sakiyama, Y.4    Matsumoto, S.5    Nishikawa, S.-I.6
  • 16
    • 0028306799 scopus 로고
    • Myeloid differentiation mediated through retinoic acid receptor/retinoic X receptor (RXR) not RXR/RXR pathway
    • Dawson MI, Elstner E, Kizaki M, Chen DL, Pakkala S, Kerner B, Koeffler HP: Myeloid differentiation mediated through retinoic acid receptor/retinoic X receptor (RXR) not RXR/RXR pathway. Blood 84:446, 1994
    • (1994) Blood , vol.84 , pp. 446
    • Dawson, M.I.1    Elstner, E.2    Kizaki, M.3    Chen, D.L.4    Pakkala, S.5    Kerner, B.6    Koeffler, H.P.7
  • 17
    • 0029081592 scopus 로고
    • Multimeric complexes of the PML-retinoic acid receptor α fusion protein in acute promyelocytic leukemia cells and interference with retinoic and peroxisome-proliferator signaling pathways
    • Jansen JH, Mahfoudi A, Rambaud S, Lavau C, Wahli W, Dejean A: Multimeric complexes of the PML-retinoic acid receptor α fusion protein in acute promyelocytic leukemia cells and interference with retinoic and peroxisome-proliferator signaling pathways. Proc Natl Acad Sci USA 92:7401, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7401
    • Jansen, J.H.1    Mahfoudi, A.2    Rambaud, S.3    Lavau, C.4    Wahli, W.5    Dejean, A.6
  • 18
    • 0027328057 scopus 로고
    • PML-RAR homodimers: Distinct DNA binding properties and heteromeric interactions with RXR
    • Perez A, Kastner P, Sethi S, Lutz Y, Reibel C, Chambon P: PML-RAR homodimers: Distinct DNA binding properties and heteromeric interactions with RXR. EMBO J 12:3171, 1993
    • (1993) EMBO J , vol.12 , pp. 3171
    • Perez, A.1    Kastner, P.2    Sethi, S.3    Lutz, Y.4    Reibel, C.5    Chambon, P.6
  • 20
    • 0025201879 scopus 로고
    • All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results
    • Castaigne S, Chomienne C, Daniel MT, Ballerini P, Berger R, Fenaux P, Degos L: All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results. Blood 76:1704, 1990
    • (1990) Blood , vol.76 , pp. 1704
    • Castaigne, S.1    Chomienne, C.2    Daniel, M.T.3    Ballerini, P.4    Berger, R.5    Fenaux, P.6    Degos, L.7
  • 21
    • 0025241453 scopus 로고
    • All-trans retinoic acid in acute promyelocytic leukemias. II. in vitro studies: Structure-function relationship
    • Chomienne C, Ballerini P, Balitrand N, Daniel MT, Fenaux P, Castaigne S, Degos L: All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: Structure-function relationship. Blood 76:1710, 1990
    • (1990) Blood , vol.76 , pp. 1710
    • Chomienne, C.1    Ballerini, P.2    Balitrand, N.3    Daniel, M.T.4    Fenaux, P.5    Castaigne, S.6    Degos, L.7
  • 26
    • 0028966628 scopus 로고
    • Cellular localization and tissue distribution of PML proteins as defined by a new monoclonal antibody (PG-M3) directed against the aminoterminal portion of the PML gene product. Preferential expression of PML in post-mitotic cells
    • Flenghi L, Fagioli M, Tomassoni L, Pileri S, Pacini R, Grignani F, Casini T, Ferrucci PF, Martelli MF, Pelicci PG, Falini B: Cellular localization and tissue distribution of PML proteins as defined by a new monoclonal antibody (PG-M3) directed against the aminoterminal portion of the PML gene product. Preferential expression of PML in post-mitotic cells. Blood 85:1871, 1995
    • (1995) Blood , vol.85 , pp. 1871
    • Flenghi, L.1    Fagioli, M.2    Tomassoni, L.3    Pileri, S.4    Pacini, R.5    Grignani, F.6    Casini, T.7    Ferrucci, P.F.8    Martelli, M.F.9    Pelicci, P.G.10    Falini, B.11
  • 28
    • 0028179010 scopus 로고
    • A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein
    • Dyck JA, Maul GG, Miller WH Jr, Chen JD, Kakizuka A, Evans RM: A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein. Cell 76:333, 1994
    • (1994) Cell , vol.76 , pp. 333
    • Dyck, J.A.1    Maul, G.G.2    Miller Jr., W.H.3    Chen, J.D.4    Kakizuka, A.5    Evans, R.M.6
  • 29
  • 31
    • 0029010740 scopus 로고
    • The PML gene encodes a phosphoprotein associated with the nuclear matrix
    • Chang K-S, Fan Y-H, Andreeff M, Liu J, Mu Z-M: The PML gene encodes a phosphoprotein associated with the nuclear matrix. Blood 85:3646, 1995
    • (1995) Blood , vol.85 , pp. 3646
    • Chang, K.-S.1    Fan, Y.-H.2    Andreeff, M.3    Liu, J.4    Mu, Z.-M.5
  • 32
    • 0028942312 scopus 로고
    • Highly purified primitive hematopoietic stem cells are PML-RARα negative and generate nonclonal progenitors in acute promyelocytic leukemia
    • Turhan AG, Lemoine FM, Debert C, Bonnet ML, Baillou C, Picard F, Macintyre EA, Varet B: Highly purified primitive hematopoietic stem cells are PML-RARα negative and generate nonclonal progenitors in acute promyelocytic leukemia. Blood 85:2154, 1995
    • (1995) Blood , vol.85 , pp. 2154
    • Turhan, A.G.1    Lemoine, F.M.2    Debert, C.3    Bonnet, M.L.4    Baillou, C.5    Picard, F.6    Macintyre, E.A.7    Varet, B.8
  • 35
    • 0028575706 scopus 로고
    • Early myeloid cell-specific expression of the human cathepsin G gene in transgenic mice
    • Grisolano JL, Sclar GM, Ley TJ: Early myeloid cell-specific expression of the human cathepsin G gene in transgenic mice. Proc Natl Acad Sci USA 91:8989, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8989
    • Grisolano, J.L.1    Sclar, G.M.2    Ley, T.J.3
  • 36
    • 0025059471 scopus 로고
    • Transcriptional activation of the human serine protease gene CSP-B in T-lymphocytes
    • Hanson RD, Ley TJ: Transcriptional activation of the human serine protease gene CSP-B in T-lymphocytes. Mol Cell Biol 10:5655, 1990
    • (1990) Mol Cell Biol , vol.10 , pp. 5655
    • Hanson, R.D.1    Ley, T.J.2
  • 37
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
    • (1987) Anal Biochem , vol.162 , pp. 156
    • Chomczynski, P.1    Sacchi, N.2
  • 39
    • 0029888693 scopus 로고    scopus 로고
    • A retrovirus carrying the promyelocyte-retinoic acid receptor PML-RARα fusion gene transforms hematopoietic progenitors in vitro and induces acute leukemia
    • Altabef M, Garcia M, Lavau C, Bae S-C, Dejean A, Samarut J: A retrovirus carrying the promyelocyte-retinoic acid receptor PML-RARα fusion gene transforms hematopoietic progenitors in vitro and induces acute leukemia. EMBO J 15:2707, 1996
    • (1996) EMBO J , vol.15 , pp. 2707
    • Altabef, M.1    Garcia, M.2    Lavau, C.3    Bae, S.-C.4    Dejean, A.5    Samarut, J.6
  • 42
    • 0028961422 scopus 로고
    • Leukocyte integrin CD11b promoter directs expression in lymphocytes and granulocytes in transgenic mice
    • Back A, East K, Hickstein D: Leukocyte integrin CD11b promoter directs expression in lymphocytes and granulocytes in transgenic mice. Blood 85:1017, 1995
    • (1995) Blood , vol.85 , pp. 1017
    • Back, A.1    East, K.2    Hickstein, D.3
  • 44
    • 0025940322 scopus 로고
    • Targeting of transgene expression to monocyte/ macrophages by the gp91-phox promoter and consequent histiocytic malignancies
    • Skalnik DG, Dorfman DM, Perkins AS, Jenkins NA, Copeland NG, Orkin SH: Targeting of transgene expression to monocyte/ macrophages by the gp91-phox promoter and consequent histiocytic malignancies. Proc Natl Acad Sci USA 88:8505, 1991
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8505
    • Skalnik, D.G.1    Dorfman, D.M.2    Perkins, A.S.3    Jenkins, N.A.4    Copeland, N.G.5    Orkin, S.H.6
  • 45
    • 0026728357 scopus 로고
    • Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma
    • McGuire EA, Rintoul CE, Sclar GM, Korsmeyer SJ: Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma. Mol Cell Biol 12:4186, 1992
    • (1992) Mol Cell Biol , vol.12 , pp. 4186
    • McGuire, E.A.1    Rintoul, C.E.2    Sclar, G.M.3    Korsmeyer, S.J.4
  • 46
    • 0029120627 scopus 로고
    • The acute promyelocytic leukemia-specific PML-RARα fusion protein reduces the frequency of commitment to apoptosis upon growth factor deprivation of GM-CSF-dependent myeloid cells
    • Rogaia D, Grignani F, Nicolleti I, Pelicci PG: The acute promyelocytic leukemia-specific PML-RARα fusion protein reduces the frequency of commitment to apoptosis upon growth factor deprivation of GM-CSF-dependent myeloid cells. Leukemia 9:1467, 1995
    • (1995) Leukemia , vol.9 , pp. 1467
    • Rogaia, D.1    Grignani, F.2    Nicolleti, I.3    Pelicci, P.G.4
  • 47
    • 0027407954 scopus 로고
    • Normal development and growth of mice carrying a targeted disruption of the α1 retinoic acid receptor gene
    • Li E, Sucov HM, Lee K-F, Evans RM, Jaenisch R: Normal development and growth of mice carrying a targeted disruption of the α1 retinoic acid receptor gene. Proc Natl Acad Sci USA 90:1590, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1590
    • Li, E.1    Sucov, H.M.2    Lee, K.-F.3    Evans, R.M.4    Jaenisch, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.