Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation

International Journal of Cancer

Volumn 100, Issue 1, 2002, Pages 43-48

  Delmas, Caroline ^a   Heliez, Christophe ^a   Cohen Jonathan, Elizabeth ^a   End, Dave ^b   Bonnet, Jacques ^a   Favre, Gilles ^a   Toulas, Christine ^a  

^a INSTITUT CLAUDIUS REGAUD   (France)

^b JANSSEN RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Farnesyltransferase inhibitor; Human glioma cell lines; Radiosensitization; RhoB

Indexed keywords

PROTEIN FARNESYLTRANSFERASE INHIBITOR; TIPIFARNIB;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DRUG MECHANISM; GAMMA IRRADIATION; GLIOMA CELL; IONIZING RADIATION; MITOSIS; NECROSIS; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; RADIOSENSITIZATION;

ALKYL AND ARYL TRANSFERASES; CELL DEATH; CELL SURVIVAL; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; GENE EXPRESSION; GENES, RAS; GLIOMA; HUMANS; MUTATION; QUINOLONES; RADIATION-SENSITIZING AGENTS; RAS PROTEINS; RHOB GTP-BINDING PROTEIN; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0036643779     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10439     Document Type: Article

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