Reversible G1 arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity

Journal of Biological Chemistry

Volumn 275, Issue 10, 2000, Pages 6987-6995

  Busse, Dagmar ^a,b   Doughty, Rachel S ^a   Ramsey, Timothy T ^a   Russell, William E ^a,c   Price, James O ^a,c,d   Flanagan, W Michael ^e   Shawver, Laura K ^f   Arteaga, Carlos L ^a,c,d  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Robert Bosch Stiftung   (Germany)

^c VANDERBILT INGRAM CANCER CENTER   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e GILEAD SCIENCES   (United States)

^f SUGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; MITOGEN ACTIVATED PROTEIN KINASE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; PROTEIN KINASE INHIBITOR; PROTEIN P27; RETINOBLASTOMA PROTEIN;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; ENZYME INHIBITION; HUMAN; HUMAN CELL; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL CYCLE PROTEINS; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; FEMALE; G1 PHASE; HUMANS; MICE; MICE, INBRED BALB C; MICROTUBULE-ASSOCIATED PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHORYLATION; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RETINOBLASTOMA PROTEIN; TUMOR SUPPRESSOR PROTEINS; TYRPHOSTINS; UP-REGULATION;

MUS MUSCULUS;

EID: 0034629485     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.10.6987     Document Type: Article

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