Quantitation of flavonoid constituents in Citrus fruits

Journal of Agricultural and Food Chemistry

Volumn 47, Issue 9, 1999, Pages 3565-3571

  Kawaii, Satoru ^a   Tomono, Yasuhiko ^a   Katase, Eriko ^a   Ogawa, Kazunori ^a   Yano, Masamichi ^a  

^a NATIONAL INSTITUTE OF FRUIT TREE SCIENCE   (Japan)

Author keywords

Citrus; Flavonoids; HPLC; Multivariate analysis; Near citrus relatives

Indexed keywords

FLAVONE DERIVATIVE; FLAVONOID;

ARTICLE; CHEMISTRY; CHEMOTAXONOMY; CITRUS FRUIT; CLASSIFICATION; FOOD ANALYSIS; FREEZE DRYING; NONHUMAN; PHYTOCHEMISTRY; QUANTITATIVE ASSAY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SPECIES DIFFERENCE; STATISTICAL ANALYSIS;

ANALYSIS OF VARIANCE; CITRUS; FLAVONOIDS; FREEZE DRYING;

CITRUS;

EID: 0032868236     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf990153+     Document Type: Article

References (31)

1. Albach, R. F.; Redman, G. H. Composition and inheritance of flavanones in citrus fruit. Phytochemistry 1969, 8, 127-143.
2. Attaway, J. A. Medical benefits of juice flavonoids. In The Citrus Processing and Technology Conference; Lake Alfred, FL, 1992; pp 207-219.
3. Benavente-García, O.; Castillo, J.; Marin, F. R.; Ortuño, A.; Del Río, J. A. Use and properties of Citrus flavonoids. J. Agric. Food Chem. 1997, 45, 4506-4515.
4. Chen, J.; Montanari, A. M.; Widmer, W. W. Two new polymethoxylated flavones, a class of compounds with potential anticancer activity, isolated from cold pressed Dancy tangerine peel oil solids. J. Agric. Food Chem. 1997, 45, 364-368.
5. Deschner, E. E.; Ruperto, J.; Wong, G.; Newmark, H. L. Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis 1991, 12, 1193-1196.
6. Gaydou, E. M.; Bianchini, J.-P.; Randriamiharisoa, R. P. Orange and mandarin peel oils differentiation using polymethoxylated flavone composition. J. Agric. Food Chem. 1987, 35, 525-529.
7. Gentili, B.; Horowitz, R. M. Flavonoids of citrus-VII. Limocitrol and isolimocitrol. Tetrahedron 1964, 20, 2313-2318.
8. Handa, T.; Oogaki, C. Numerical taxonomic study of Citrus L. and Fortunella Swingle using morphological characters. Application of multivariate analysis. J. Jpn. Soc. Hortic. Sci. 1986, 54, 145-154.
9. Horowitz, R. M. Flavonoids of citrus. I. Isolation of diosmin from lemons (Citrus limon). J. Org. Chem. 1958, 21, 1184-1185.
10. Horowitz, R. M. Flavonoids of citrus. II. Isolation of a new flavonol from lemons. J. Am. Chem. Soc. 1957, 79, 6561-6562.
11. Horowitz, R. M.; Gentili, B. Flavonoid compounds of Citrus. III. Isolation and structure of eriodictyol glycoside. J. Am. Chem. Soc. 1960a, 82, 2803-2806.
12. Horowitz, R. M.; Gentili, B. Flavonoids of citrus. IV. Isolation of some aglycones from the lemon (Citrus lemon). J. Org. Chem. 1960b, 25, 2183-2187.
13. Kanes, K.; Tisserat, B.; Berhow, M.; Vandercook, C. Phenolic composition of various tissues of Rutaceae species. Phytochemistry 1992, 31, 967-974.
14. Kawaii, S.; Tomono, Y.; Katase, E.; Ogawa, K.; Yano, M. HL-60 differentiating activity and flavonoid content of the readily extractable fraction prepared from Citrus juices. J. Agric. Food Chem. 1999a, 47, 128-135.
15. Kawaii, S.; Tomono, Y.; Katase, E.; Ogawa, K.; Yano, M. Effect of citrus flavonoids on HL-60 cell differentiation. Anticancer Res. 1999b, 19 (2A), 1261-1269.
16. Kawaii, S.; Tomono, Y.; Katase, E.; Ogawa, K.; Yano, M. Antiproliferative activity of flavonoids on several cancer cell lines. Biosci., Biotechnol., Biochem. 1999c, 63, 896-899.
17. Koeffler, H. P. Induction of differentiation of human acute myelogenous leukemia cell: Therapeutic implications. Blood 1983, 62, 709-721.
18. Park, G. L.; Avery, S. M.; Byers, J. L.; Nelson, D. B. Identification of bioflavonoids from citrus. Food Technol. 1983, 37, 98-105.
19. Stavric, B. Antimutagens and anticarcinogens in foods. Food Chem. Toxicol. 1994, 32, 79-90.
20. Sugiyama, S.; Umehara, K.; Kuroyanagi, M.; Ueno, A.; Taki, T. Studies on the differentiation inducers of myeloid leukemic cells from Citrus species. Chem. Pharm. Bull. 1993, 41, 714-719.
21. Swingle, W. T. The botany of Citrus and its relatives of the orange subfamily. In The Citrus Industry; Webber, H. J., Batchelor, L. D., Eds.; University of California Press: Berkeley, CA, 1943; Vol. I.
22. Tanaka, T. Misunderstanding with regards citrus classification and nomenclature. Bull. Univ. Osaka Prefect., Ser. B 1969, 21, 139-145.
23. Tanaka, T.; Makita, H.; Kawabata, K.; Mori, H.; Kakumoto, M.; Satoh, K.; Hara, A.; Sumida, T.; Tanaka, T.; Ogawa, H. Chemoprevention of azoxymethane-induced rat colon carcinogenesis by the naturally occurring flavonoids, diosmin and hesperidin. Carcinogenesis 1997, 18, 957-965.
24. Ting, S. V.; Rouseff, R. L.; Dougherty, M. H.; Attaway, J. A. Determination of some methoxylated flavones in citrus juices by high performance liquid chromatography. J. Food Sci. 1979, 43, 69-71.
25. Tsuchida, T.; Yamamoto, T.; Yamamoto, K.; Hitomi, N.; Kosaka, N.; Okada, M.; Komatsu, K.; Namba, T. Study on the botanical origins and the quality evaluation of crude drugs derived from Citrus and related genera (III). Chemical constituents of peels of Citrus, Fortunella and Poncirus. Nat. Med. 1997, 51, 205-223.
26. Vandercook, C. E.; Stevenson, R. G. Lemon juice composition. Identification of the major phenolic compounds and estimation by paper chromatography. J. Agric. Food Chem. 1966, 14, 450-454.
27. Vandercook, C. E.; Tisserat, B. Flavonoid changes in developing lemons grown in vivo and in vitro. Phytochemistry 1989, 28, 799-803.
28. Verma, A. K.; Johnson, J. A.; Gould, M. N.; Tanner, M. A. Inhibition of 7,12-dimethylbenz[a]anthracene and N-nitromethylurea induced rat mammary cancer by dietary flavonol quercetin. Cancer Res. 1988, 48, 5754-5758.
29. Wattenberg, L. W. Chemoprevention of cancer. Cancer Res. 1985, 45, 1-8.
30. Wattenberg, L. Inhibition of carcinogenesis by minor anutrient constituents of the diet. Proc. Nutr. Soc. 1990, 49, 173-183.
31. Wei, H.; Tye, L.; Bresnick, E.; Birt, D. F. Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumour promotion in mice. Cancer Res. 1990, 50, 499-506.