Interplay between MRP Inhibition and Metabolism of MRP Inhibitors: The Case of Curcumin

Chemical Research in Toxicology

Volumn 16, Issue 12, 2003, Pages 1642-1651

  Wortelboer, Heleen M ^a   Usta, Mustafa ^a   Van Der Velde, Astrid E ^a   Boersma, Marelle G ^b   Spenkelink, Bert ^b   Van Zanden, Jelmer J ^b   Rietjens, Ivonne M C M ^b   Van Bladeren, Peter J ^b,c   Cnubben, Nicole H P ^a,b  

^a TNO   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CURCUMIN; GLUTATHIONE; GLUTATHIONYLCURCUMIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; IC 50; INHIBITION KINETICS; INSECT CELL; INTRACELLULAR TRANSPORT; MEMBRANE VESICLE; METABOLISM; MONOLAYER CULTURE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BACULOVIRIDAE; CELL LINE; CURCUMIN; CYCLOSPORINE; DINITROCHLOROBENZENE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; ETHACRYNIC ACID; FLUORESCEINS; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; P-GLYCOPROTEIN; P-GLYCOPROTEINS; PROPIONATES; QUINOLINES; RECOMBINANT PROTEINS; SPODOPTERA;

ANIMALIA; APUS APUS; INSECTA;

EID: 0346998186     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx034101x     Document Type: Article

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