Increased expression and processing of caspase-12 after traumatic brain injury in rats

Journal of Neurochemistry

Volumn 88, Issue 1, 2004, Pages 78-90

  Larner, Stephen F ^a   Hayes, Ronald L ^a   McKinsey, Deborah M ^a   Pike, Brian R ^a,b   Wang, Kevin K W ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES   (United States)

Author keywords

Apoptosis; Calpain; Caspase; Traumatic brain injury; Unfolded protein response

Indexed keywords

CASPASE 12; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN INJURY; CELL FRACTIONATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE INDUCTION; HIPPOCAMPUS; HOMEOSTASIS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INJURY SCALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALIA;

EID: 0346733036     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02141.x     Document Type: Article

References (60)

1. Aridor M. and Balch W. E. (1999) Integration of endoplasmic reticulum signaling in health and disease. Nature Med. 5, 745-751.
2. Beer R., Franz G., Schöpf M., Reindl M., Zelger B., Schmutzhard E., Poewe W. and Kampfl A. (2000) Expression of Fas and Fas ligand after experimental traumatic brain injury in the rat. J. Cereb. Blood Flow Metab. 20, 669-677.
3. Bertolotti A., Zhang Y., Hendershot L. M., Harding H. P. and Ron D. (2000) Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat. Cell Biol. 2, 326-332.
4. Bitko V. and Barik S. (2001) An endoplasmic reticulum-specific stress-activated caspase (caspase-12) is implicated in the apoptosis of A549 epithelial cells by respiratory syncytial virus. J. Cell Biochem. 80, 441-454.
5. Bradley J. R. and Pober J. S. (2001) Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene 20, 6482-6491.
6. Clark R. S., Kochanek P. M., Chen M., Watkins S. C., Marion D. W., Chen J., Hamilton R. L., Loeffert J. E. and Graham S. H. (1999) Increases in Bcl-2 and cleavage of caspase-I and caspase-3 in human brain after head injury. FASEB J. 13, 813-821.
7. Clark R. S., Kochanek P. M., Watkins S. C. et al. (2000) Caspase-3 mediated neuronal death after traumatic brain injury in rats. J. Neurochem. 74, 740-753.
8. Cohen G. M. (1997) Caspases: the executioners of apoptosis. Biochem. J. 326, 1-16.
9. Colicos M. A., Dixon C. E. and Dash P. K. (1996) Delayed, selective neuronal death following experimental cortical impact injury in rats: possible role in memory defects. Brain Res. 739, 111-119.
10. Conti A. C., Raghupathi R., Trojanowski J. Q. and McIntosh T. K. (1998) Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period. J. Neurosci. 18, 5663-5672.
11. Daniel P. T. (2000) Dissecting the pathways to death. Leukemia 14, 2035-2044.
12. DeGracia D. J., Kumar R., Owen C. R., Krause G. S. and White B. C. (2002) Review: Molecular pathways of protein synthesis inhibition during brain reperfusion: implications for neuronal survival or death. J. Cereb. Blood Flow Metab. 22, 127-141.
13. Dixon C. E., Clifton G. L., Lighthall J. W., Yaghmai A. A. and Hayes R. L. (1991) A controlled cortical impact model of traumatic brain injury in the rat. J. Neurosci. Methods 39, 252-262.
14. Fischer H., Koenig U., Eckhart L. and Tschachler E. (2002) Human caspase-12 has acquired deleterious mutations. Biochem. Biophys. Res. Commun. 293, 722-726.
15. Harding H. P., Zhang Y. and Ron D. (1977) Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397, 271-274.
16. Harding H. P., Zhang Y., Bertolotti A., Zeng H. and Ron D. (2000) Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol. Cell 5, 897-904.
17. Henshall D. C., Chen J. and Simon R. P. (2000) Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures. J. Neurochem. 74, 1215-1223.
18. Imaizumi K., Miyoshi K., Katayama T., Yoneda T., Taniguchi M., Kudo T. and Tohyama M. (2001) Review: The unfolded protein response and Alzheimer's disease. Biochim. Biophys. Acta 1536, 85-96.
19. Jacobson M. D., Well M. and Raff M. C. (1997) Programmed cell death in animal development. Cell 88, 347-354.
20. Johnson F. B., Sinclair D. A. and Guarente L. (1999) Molecular biology of aging. Cell 96, 291-302.
21. Kaufman R. J. (1999) Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev. 13, 1211-1233.
22. Keane R. W., Kraydieh S., Lotocki G., Ofelia F. A., Aldana P. and Dietrich W. D. (2001) Apoptotic and antiapoptotic mechanisms after traumatic brain injury. J. Cereb. Blood Flow Metab. 21, 1189-1198.
23. Kohno K., Normington K., Sambrook J., Gething M. J. and Mori K. (1993) The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum. Mol. Cell Biol. 13, 877-890.
24. Mattson M. P., LaFerla F. M., Chan S. L., Leissring M. A., Shepel P. N. and Geiger J. D. (2000) Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders. Trends Neurosci. 23, 222-229.
25. Mori K., Sant A., Kohno K., Normington K., Gething M. J. and Sambrook J. F. (1992) A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins. EMBO J. 11, 2583-2593.
26. Morishima N., Nakanishi K., Takenouchi H., Shibata G. and Yasuhiko Y. (2002) An endoplasmic reticulum stress-specific caspase cascade in apoptosis: cytochrome c-independent activation of caspase-9 by caspase-12. J. Biol. Chem. 277, 34287-34294.
27. Mouw G., Zechel J. L., Gamboa J., Lust W. D., Selman W. R. and Ratcheson R. A. (2003) Activation of caspase-12, an endoplasmic reticulum resident caspase, after permanent focal ischemia in rat. Neuroreport 14, 183-186.
28. Nakagawa T. and Yuan J. (2000) Cross-talk between two cysteine protease families: activation of caspase-12 by calpain in apoptosis. J. Biol. Chem. 150, 887-894.
29. Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B. A. and Yuan J. (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β. Nature 403, 98-103.
30. Nakamura K., Bossy-Wetzel E., Burns K., Fadel M. P., Lozyk M., Goping I. S., Opas M., Bleackley R. C., Green D. R. and Michalak M. (2000) Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis. J. Biol. Chem. 150, 731-740.
31. Natoli G., Costanzo A., Ianni A., Templeton D. J., Woodgett J. R., Balsano C. and Levrero M. (1997) Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway. Science 275, 200-203.
32. Newcomb J. K., Kampfl A., Posmantur R. M., Zhao X., Pike B. R., Liu S., Clifton G. L. and Hayes R. L. (1997) Immunohistochemical study of calpain-mediated breakdown products to alpha-spectrin following controlled cortical impact injury in the rat. J. Neurotrauma 14, 369-383.
33. Newcomb J. K., Zhao X., Pike B. R. and Hayes R. L. (1999) Temporal profile of apoptotic-like changes in neurons and astrocytes following controlled cortical impact injury in the rat. Exp. Neurol. 158, 76-88.
34. Oppenheim R. W. (1991) Cell death during development of the nervous system. Annu. Rev. Neurosci. 14, 453-501.
35. Paschen W. and Doutheil J. (1999) Disturbances of the functioning of endoplasmic reticulum: a key mechanism underlying neuronal cell injury. J. Cereb. Blood Flow Metab. 19, 1-18.
36. Pelletier M. R., Wadia J. S., Mills L. R. and Carlen P. L. (1999) Seizure-induced cell death produced by repeated tetanic stimulation in vitro: possible role of endoplasmic reticulum calcium stores. J. Neurophysiol. 81, 3054-3064.
37. Pike B. R., Zhao X., Newcomb J. K., Posmuntar R. M., Wang K. K. and Hayes R. L. (1998) Regional calpain and caspase-3 proteolysis of alpha-spectrin after traumatic brain injury. Neuroreport 9, 2437-2442.
38. Qui J., Whalen M. J., Lowenstein P., Fiskurn G., Fahy B., Darwish R., Aarabi B., Yuan J. and Moskowitz M. A. (2002) Upregulation of the Fas receptor death inducing-signaling complex in traumatic brain injury in mice and humans. J. Neurosci. 22, 3504-3511.
39. Raff M. C., Barres B. A., Burne J. F., Coles H. S., Ishizaki Y. and Jacobson M. D. (1993) Programmed cell death and the control of cell survival: lessons from the nervous system. Science 262, 695-700.
40. Raghupathi R., Graham D. I. and McIntosh T. K. (2000) Apoptosis after traumatic brain injury. J. Neurotrauma 17, 927-938.
41. Rao R. V., Hermel E., Castro-Obregon S., del Rio G., Ellerby L. M., Ellerby H. M. and Bredesen D. E. (2001) Coupling endoplasmic reticulum stress to the cell death program. J. Biol. Chem. 276, 33869-33874.
42. Rao R. V., Castro-Obregon S., Frankowski H., Schuler M., Stoka V., del Rio G., Bredesen D. E. and Ellerby H. M. (2002) Coupling endoplasmic reticulum stress to the cell death program. J. Biol. Chem. 277, 21836-21842.
43. Rink A., Fung K. M., Trojanowski J. Q., Lee B. M., Neugebauer E. and McIntosh T. K. (1995) Evidence of apoptotic cell death after experimental traumatic brain injury in the rat. Am. J. Pathol. 147, 1575-1583.
44. Shibata M., Hattori H., Sasaki T., Gotoh J., Hamada J. and Fukuuchi Y. (2003) Activation of caspase-12 by endoplasmic reticulum stress induced by transient middle cerebral artery occlusion in mice. Neuroscience 118, 491-499.
45. Soto C. (2003) Unfolding the role of protein misfolding in neurodegenerative diseases. Nat. Rev. Neurosci. 4, 49-60.
46. Tada K., Okazaki T., Sakon S. et al. (2001) Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappaB activation and protection from cell death. J. Biol. Chem. 276, 36530-36534.
47. Taupin V., Toulmond S., Serrano A., Benavides J. and Zavala F. (1993) Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre- and post-traumatic treatment with Ro5, 4864, a peripheral-type (p site) benzodiazepine ligand. J. Neuroimmunol. 42, 177-185.
48. Tinhofer I., Anether G., Senfter M., Pfaller K., Bernhard D., Hara M. and Greil R. (2002) Stressful death of T-ALL tumor cells after treatment with the anti-tumor agent Tetrocarcin-A. FASEB J. 16, 1295-1297.
49. Tolentino P. J., DeFord S. M., Notterpek L., Glenn C. C., Pike B. R., Wang K. K. W. and Hayes R. L. (2002) Up-regulation of tissue-type transglutaminase after traumatic brain injury. J. Neurochem. 80, 579-588.
50. Vaux D. L. and Korsmeyer S. J. (1999) Cell death in development. Cell 96, 245-254.
51. Weber J. T., Rzigalinski B. A. and Ellis E. F. (2001) Traumatic injury of cortical neurons causes changes in intracellular calcium stores and capacitative calcium influx. J. Biol. Chem. 276, 1800-1807.
52. Xie Q., Khaoustov V. I., Chung C. C., Sohn J., Krishnan B., Lewis D. E. and Yoffe B. (2002) Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology 36, 592-601.
53. Xiong Y., Gu Q., Peterson P. L., Muizelaar J. P. and Lee C. P. (1997) Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury. J. Neurotrauma 14, 23-34.
54. Yakovlev A. G. and Faden A. L. (2001) Caspase-dependent apoptotic pathways in CNS injury. Mol. Neurobiol. 24, 131-144.
55. Yakovlev A. G., Knoblach S. M., Fan L., Fox G. B., Goodnight R. and Faden A. I. (1997) Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. J. Neurosci. 17, 7415-7424.
56. Yang M. S., DeWitt D. S., Becker D. P. and Hayes R. L. (1985) Regional brain metabolite levels following mild experimental head injury in the cat. J. Neurosurg. 63, 617-621.
57. Yoneda T., Imaizumi K., Oono K., Yui D., Gomi F., Katayama T. and Tohyama M. (2001) Activation of caspase-12, an endoplasmic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J. Biol. Chem. 276, 13935-13940.
58. Yoshida H., Haze K., Yanagi H., Yura T. and Mori K. (1998) Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins; involvement of basic-leucine zipper transcription factors. J. Biol. Chem. 273, 33741-33749.
59. Yu Z., Luo H., Fu W. and Mattson M. P. (1999) The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp. Neurol. 155, 302-314.
60. Yuan J. and Yankner B. A. (2000) Apoptosis in the nervous system. Nature 407, 802-809.