-
1
-
-
0027430690
-
Triplex formation inhibits HER-2/neu transcription in vitro
-
Ebbinghaus SW, Gee JE, Rodu B, et al.: Triplex formation inhibits HER-2/neu transcription in vitro. J Clin Invest 1993;92:2433-2439.
-
(1993)
J Clin Invest
, vol.92
, pp. 2433-2439
-
-
Ebbinghaus, S.W.1
Gee, J.E.2
Rodu, B.3
-
2
-
-
0028998491
-
Inhibition of in vitro transcription by a triplex-forming oligonucleotide targeted to human c-myc P2 promoter
-
Kim HG, Miller DM: Inhibition of in vitro transcription by a triplex-forming oligonucleotide targeted to human c-myc P2 promoter. Biochemistry 1995;34:8165-8171.
-
(1995)
Biochemistry
, vol.34
, pp. 8165-8171
-
-
Kim, H.G.1
Miller, D.M.2
-
3
-
-
0030014315
-
C-fos protooncogene transcription can be modulated by oligonucleotide-mediated formation of triplex structures in vitro
-
Lavrovsky Y, Stoltz RA, Vlassov VV, et al.: C-fos protooncogene transcription can be modulated by oligonucleotide-mediated formation of triplex structures in vitro. Eur J Biochem 1996;238:582-590.
-
(1996)
Eur J Biochem
, vol.238
, pp. 582-590
-
-
Lavrovsky, Y.1
Stoltz, R.A.2
Vlassov, V.V.3
-
4
-
-
0032562204
-
Inhibition of transcription of the human c-myc protooncogene by intermolecular triples
-
Kim HG, Reddoch JF, Mayfield C, et al.: Inhibition of transcription of the human c-myc protooncogene by intermolecular triples. Biochemistry 1998;37:2299-2304.
-
(1998)
Biochemistry
, vol.37
, pp. 2299-2304
-
-
Kim, H.G.1
Reddoch, J.F.2
Mayfield, C.3
-
5
-
-
0032562127
-
A novel triplex-forming oligonucleotide targeted to human cyclin D (bcl-1, proto-oncogene) promoter inhibits transcription in HeLa cells
-
Kim HG, Miller DM: A novel triplex-forming oligonucleotide targeted to human cyclin D (bcl-1, proto-oncogene) promoter inhibits transcription in HeLa cells. Biochemistry 1998;37:2666-2672.
-
(1998)
Biochemistry
, vol.37
, pp. 2666-2672
-
-
Kim, H.G.1
Miller, D.M.2
-
6
-
-
0034794290
-
Preliminary phase I results of G3139 (bcl-2 antisense oligonucleotide) therapy in combination with docetaxel in hormone-refractory prostate cancer
-
Tolcher AW: Preliminary phase I results of G3139 (bcl-2 antisense oligonucleotide) therapy in combination with docetaxel in hormone-refractory prostate cancer. Semin Oncol 2001;28(Suppl 15):67-70.
-
(2001)
Semin Oncol
, vol.28
, Issue.SUPPL. 15
, pp. 67-70
-
-
Tolcher, A.W.1
-
7
-
-
0036137646
-
Pharmacokinetics of Bcl-2 antisense oligonucleotide (G3139) combined with doxorubicin in SCID mice bearing human breast cancer solid tumor xenografts
-
Lopes D, Mayer LD: Pharmacokinetics of Bcl-2 antisense oligonucleotide (G3139) combined with doxorubicin in SCID mice bearing human breast cancer solid tumor xenografts. Cancer Chemother Pharmacol 2000;49:57-68.
-
(2000)
Cancer Chemother Pharmacol
, vol.49
, pp. 57-68
-
-
Lopes, D.1
Mayer, L.D.2
-
8
-
-
0031241407
-
Ribozyme-mediated inhibition of a Philadelphia chromosome-positive acute lymphoblastic leukemia cell line expressing the p190 bcr-abl oncogene
-
Snyder DS, Wu Y, McMahon R, et al.: Ribozyme-mediated inhibition of a Philadelphia chromosome-positive acute lymphoblastic leukemia cell line expressing the p190 bcr-abl oncogene. Biol Blood Marrow Transplant 1997;3:179-186.
-
(1997)
Biol Blood Marrow Transplant
, vol.3
, pp. 179-186
-
-
Snyder, D.S.1
Wu, Y.2
McMahon, R.3
-
9
-
-
0035179138
-
Reversion of the malignant phenotype of gastric cancer cell SGC7901 by c-erbB-2-specific hammer-head ribozyme
-
Bi F, Fan D, Hui H, et al.: Reversion of the malignant phenotype of gastric cancer cell SGC7901 by c-erbB-2-specific hammer-head ribozyme. Cancer Gene Ther 2001;8:835-842.
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 835-842
-
-
Bi, F.1
Fan, D.2
Hui, H.3
-
10
-
-
0034881625
-
A hammerhead ribozyme suppresses expression of hepatocyte growth factor/scatter factor receptor c-MET and reduces migration and invasiveness of breast cancer cells
-
Jiang WG, Grimshaw D, Lane J, et al.: A hammerhead ribozyme suppresses expression of hepatocyte growth factor/scatter factor receptor c-MET and reduces migration and invasiveness of breast cancer cells. Clin Cancer Res 2001;7:2555-2562.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2555-2562
-
-
Jiang, W.G.1
Grimshaw, D.2
Lane, J.3
-
11
-
-
0036365052
-
In vivo targeting of SF/HGF and c-met expression via UlsnRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis
-
Abounader R, Lai B, Luddy C, et al.: In vivo targeting of SF/HGF and c-met expression via UlsnRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis. FASEB J 2002;16:108-110.
-
(2002)
FASEB J
, vol.16
, pp. 108-110
-
-
Abounader, R.1
Lai, B.2
Luddy, C.3
-
12
-
-
0036134311
-
A novel therapeutic technology of specific RNA inhibition for acute promyelocytic leukemia: Improved design of maxizymes against PML/RARalpha mRNA
-
Suwanal H, Matsushita H, Kobayashi H, et al.: A novel therapeutic technology of specific RNA inhibition for acute promyelocytic leukemia: Improved design of maxizymes against PML/RARalpha mRNA. Int J Oncol 2002;20:127-130.
-
(2002)
Int J Oncol
, vol.20
, pp. 127-130
-
-
Suwanal, H.1
Matsushita, H.2
Kobayashi, H.3
-
13
-
-
0036143133
-
Ribozyme-mediated downregulation of human metallothionein II(a) induces apoptosis in human prostate and ovarian cancer cell lines
-
Tekur S, Ho SM: Ribozyme-mediated downregulation of human metallothionein II(a) induces apoptosis in human prostate and ovarian cancer cell lines. Mol Carcinog 2002;33:44-55.
-
(2002)
Mol Carcinog
, vol.33
, pp. 44-55
-
-
Tekur, S.1
Ho, S.M.2
-
14
-
-
0032511990
-
Characterization of a new intrabody directed against the N-terminal region of human p53
-
Cohen PA, Mani JC, Lane DP: Characterization of a new intrabody directed against the N-terminal region of human p53. Oncogene 1998;17:2445-2456.
-
(1998)
Oncogene
, vol.17
, pp. 2445-2456
-
-
Cohen, P.A.1
Mani, J.C.2
Lane, D.P.3
-
15
-
-
18544408628
-
A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): A phase I trial
-
Alvarez RD, Barnes MN, Gomez-Navarro J, et al.: A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): A phase I trial. Clin Cancer Res 2000;6:3081-3087.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3081-3087
-
-
Alvarez, R.D.1
Barnes, M.N.2
Gomez-Navarro, J.3
-
16
-
-
0036570976
-
Characterization of anti-cyclin E single-chain Fv antibodies and intrabodies in breast cncer cells: Enhanced intracellular stability of novel sFv-F(c) intrabodies
-
Strube RW, Chen SY: Characterization of anti-cyclin E single-chain Fv antibodies and intrabodies in breast cncer cells: Enhanced intracellular stability of novel sFv-F(c) intrabodies. J Immunol Methods 2002;263:149-167.
-
(2002)
J Immunol Methods
, vol.263
, pp. 149-167
-
-
Strube, R.W.1
Chen, S.Y.2
-
17
-
-
0030875896
-
Adenoviral-mediated gene transfer of a constitutively active retinoblastoma gene inhibits human pancreatic tumor cell proliferation
-
Simeone DM, Cascarelli A, Logsdon CD: Adenoviral-mediated gene transfer of a constitutively active retinoblastoma gene inhibits human pancreatic tumor cell proliferation. Surgery 1997;122:428-433.
-
(1997)
Surgery
, vol.122
, pp. 428-433
-
-
Simeone, D.M.1
Cascarelli, A.2
Logsdon, C.D.3
-
18
-
-
0031813862
-
Suppression of human glioma growth by adenovirus-mediated Rb gene transfer
-
Fueyo J, Gomez-Manzano C, Yung WK, et al.: Suppression of human glioma growth by adenovirus-mediated Rb gene transfer. Neurology 1998;50:1307-1315.
-
(1998)
Neurology
, vol.50
, pp. 1307-1315
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Yung, W.K.3
-
19
-
-
0033572553
-
Growth suppression of human ovarian cancer cells by adenovirus-mediated transfer of the PTEN gene
-
Minaguchi T, Mori T, Kanamori Y, et al.: Growth suppression of human ovarian cancer cells by adenovirus-mediated transfer of the PTEN gene. Cancer Res 1999;59:6063-6067.
-
(1999)
Cancer Res
, vol.59
, pp. 6063-6067
-
-
Minaguchi, T.1
Mori, T.2
Kanamori, Y.3
-
20
-
-
0033781847
-
p21 gene expression as an indicator for the activity of adenovirus-p53 gene therapy in non-small cell lung cancer patients
-
Boulay J-L, Perruchoud AP, Reuter J, et al.: p21 gene expression as an indicator for the activity of adenovirus-p53 gene therapy in non-small cell lung cancer patients. Cancer Gene Ther 2000;7:1215-1219.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 1215-1219
-
-
Boulay, J.-L.1
Perruchoud, A.P.2
Reuter, J.3
-
21
-
-
0035074864
-
PRb2/p130 gene overexpression induces astrocyte differentiation
-
Galderisi U, Melone MA, Jori FP, et al.: PRb2/p130 gene overexpression induces astrocyte differentiation. Mol Cell Neurosci 2001;17:415-425.
-
(2001)
Mol Cell Neurosci
, vol.17
, pp. 415-425
-
-
Galderisi, U.1
Melone, M.A.2
Jori, F.P.3
-
22
-
-
0036210391
-
p53 and PTEN/MMAC1/TEP1 gene therapy of human prostate PC-3 carcinoma xenograft, using transferrin-facilitated lipofection gene delivery strategy
-
Seki M, Iwakawa J, Cheng H, et al.: p53 and PTEN/MMAC1/TEP1 gene therapy of human prostate PC-3 carcinoma xenograft, using transferrin-facilitated lipofection gene delivery strategy. Hum Gene Ther 2002;13:761-773.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 761-773
-
-
Seki, M.1
Iwakawa, J.2
Cheng, H.3
-
23
-
-
0036021890
-
Adenovirus-mediated gene transfer of P16INK4/CDKN2 into bax-negative colon cancer cells induces apoptosis and tumor regression in vivo
-
Tamm I, Schumacher A, Karawajew L, et al.: Adenovirus-mediated gene transfer of P16INK4/CDKN2 into bax-negative colon cancer cells induces apoptosis and tumor regression in vivo. Cancer Gene Ther 2002;9:641-650.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 641-650
-
-
Tamm, I.1
Schumacher, A.2
Karawajew, L.3
-
24
-
-
0035003528
-
Gene transfer of antisense hypoxia inducible factor-1 alpha enhances the therapeutic efficacy of cancer immunotherapy
-
Sun X, Kanwar JR, Leung E, et al.: Gene transfer of antisense hypoxia inducible factor-1 alpha enhances the therapeutic efficacy of cancer immunotherapy. Gene Therapy 2001;8:638-645.
-
(2001)
Gene Therapy
, vol.8
, pp. 638-645
-
-
Sun, X.1
Kanwar, J.R.2
Leung, E.3
-
25
-
-
0036275675
-
Adeno-associated virus-mediated gene transfer of endostatin inhibits angiogenesis and tumor growth in vivo
-
Shi W, Teschendorf C, Muzyczka N, et al.: Adeno-associated virus-mediated gene transfer of endostatin inhibits angiogenesis and tumor growth in vivo. Cancer Gene Ther 2002;9:513-521.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 513-521
-
-
Shi, W.1
Teschendorf, C.2
Muzyczka, N.3
-
26
-
-
0036708236
-
Electrotransfer of gene encoding endostatin into normal and neoplastic mouse tissues: Inhibition of primary tumor growth and metastatic spread
-
Cichon T, Jamrozy L, Glogowska J, et al.: Electrotransfer of gene encoding endostatin into normal and neoplastic mouse tissues: Inhibition of primary tumor growth and metastatic spread. Cancer Gene Ther 2002;9:771-777.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 771-777
-
-
Cichon, T.1
Jamrozy, L.2
Glogowska, J.3
-
27
-
-
0036019375
-
Inhibition of angiogenesis in vitro by alphav integrin-directed antisense oligonucleotides
-
Kronenwett R, Graf T, Nedbal W, et al.: Inhibition of angiogenesis in vitro by alphav integrin-directed antisense oligonucleotides. Cancer Gene Ther 2002;9:587-596.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 587-596
-
-
Kronenwett, R.1
Graf, T.2
Nedbal, W.3
-
28
-
-
0036216692
-
HIF-1 and tumor progression: Pathophysiology and therapeutics
-
Semenza GL: HIF-1 and tumor progression: Pathophysiology and therapeutics. Trends Mol Med 2002;8(Suppl 4):S62-S67.
-
(2002)
Trends Mol Med
, vol.8
, Issue.SUPPL. 4
-
-
Semenza, G.L.1
-
29
-
-
0036463918
-
Improvement of adoptive cellular immunotherapy of human cancer suing ex-vivo gene transfer
-
Paul S, Calmels B, Acres RB: Improvement of adoptive cellular immunotherapy of human cancer suing ex-vivo gene transfer. Curr Gene Ther 2002;2:91-100.
-
(2002)
Curr Gene Ther
, vol.2
, pp. 91-100
-
-
Paul, S.1
Calmels, B.2
Acres, R.B.3
-
30
-
-
0036251452
-
A dendritic cell vaccine induces protective immunity to intracranial growth of glioma
-
Insug O, Ku G, Ertl HC, et al.: A dendritic cell vaccine induces protective immunity to intracranial growth of glioma. Anticancer Res 2002;22:613-621.
-
(2002)
Anticancer Res
, vol.22
, pp. 613-621
-
-
Insug, O.1
Ku, G.2
Ertl, H.C.3
-
31
-
-
0031649098
-
Ex-vivo gene therapy using cytokine-transduced tumor vaccines: Molecular and clinical pharmacology
-
Simons JW, Mikhak B: Ex-vivo gene therapy using cytokine-transduced tumor vaccines: Molecular and clinical pharmacology. Sem Oncol 1998;25:661-676.
-
(1998)
Sem Oncol
, vol.25
, pp. 661-676
-
-
Simons, J.W.1
Mikhak, B.2
-
32
-
-
0033664325
-
Construction and characterization of DNA vaccines encoding the single-chain variable fragment of the anti-idiotype antibody 1A7 mimicking the tumor-associated antigen disialoganglioside GD2
-
Zeytin HE, Tripathi PK, Bhattacharya-Chatterjee M, et al.: Construction and characterization of DNA vaccines encoding the single-chain variable fragment of the anti-idiotype antibody 1A7 mimicking the tumor-associated antigen disialoganglioside GD2. Cancer Gene Ther 2000;7:1426-1436.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 1426-1436
-
-
Zeytin, H.E.1
Tripathi, P.K.2
Bhattacharya-Chatterjee, M.3
-
33
-
-
85047698246
-
Comparative assessment of TCRBV diversity in T lymphocytes present in blood, metastatic lesions, and DTH sites of two melanoma patients vaccinated with an IL-7 gene-modified autologous tumor cell vaccine
-
Carsana M, Tragni G, Nicolini G, et al.: Comparative assessment of TCRBV diversity in T lymphocytes present in blood, metastatic lesions, and DTH sites of two melanoma patients vaccinated with an IL-7 gene-modified autologous tumor cell vaccine. Cancer Gene Ther 2002;9:243-253.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 243-253
-
-
Carsana, M.1
Tragni, G.2
Nicolini, G.3
-
34
-
-
0033778639
-
Induction of melanoma-associated antigen systemic immunity upon intratumoral delivery of interferon-γ retroviral vector in melanoma patients
-
Fujii S, Huang S, Fong TC, et al.: Induction of melanoma-associated antigen systemic immunity upon intratumoral delivery of interferon-γ retroviral vector in melanoma patients. Cancer Gene Ther 2000;7:1220-1230.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 1220-1230
-
-
Fujii, S.1
Huang, S.2
Fong, T.C.3
-
35
-
-
0036633912
-
Current progress in suicide gene therapy for cancer
-
Yazawa K, Fisher WE, Brunicardi FC: Current progress in suicide gene therapy for cancer. World J Surg 2002;26:783-789.
-
(2002)
World J Surg
, vol.26
, pp. 783-789
-
-
Yazawa, K.1
Fisher, W.E.2
Brunicardi, F.C.3
-
36
-
-
0027483695
-
The "bystander effect": Tumor regression when a fraction of the tumor mass is genetically modified
-
Freeman SM, Whartnby KA, Koeplin DA, et al.: The "bystander effect": Tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 1993;53:5274-5283.
-
(1993)
Cancer Res
, vol.53
, pp. 5274-5283
-
-
Freeman, S.M.1
Whartnby, K.A.2
Koeplin, D.A.3
-
37
-
-
0030916131
-
Protection of herpes simplex virus thymidine kinase-transduced cells from ganciclovir-mediated cytotoxicity by bystander cells: The Good Samaritan effect
-
Wygoda MR, Wilson MR, Davis MA, et al.: Protection of herpes simplex virus thymidine kinase-transduced cells from ganciclovir-mediated cytotoxicity by bystander cells: The Good Samaritan effect. Cancer Res 1997;57:1699-1703.
-
(1997)
Cancer Res
, vol.57
, pp. 1699-1703
-
-
Wygoda, M.R.1
Wilson, M.R.2
Davis, M.A.3
-
38
-
-
0022485359
-
Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
-
Moolten F: Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy. Cancer Res 1986;46:5276-5281.
-
(1986)
Cancer Res
, vol.46
, pp. 5276-5281
-
-
Moolten, F.1
-
39
-
-
0017639148
-
Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine
-
Ellion GB, Furman PA, Fyfe JA, et al.: Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine. Proc Natl Acad Sci USA 1977;74:5716-5720.
-
(1977)
Proc Natl Acad Sci USA
, vol.74
, pp. 5716-5720
-
-
Ellion, G.B.1
Furman, P.A.2
Fyfe, J.A.3
-
40
-
-
0036733759
-
Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer
-
Freytag SO, Khil M, Stricker H, et al.: Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer. Cancer Res 2002;62:4968-4976.
-
(2002)
Cancer Res
, vol.62
, pp. 4968-4976
-
-
Freytag, S.O.1
Khil, M.2
Stricker, H.3
-
41
-
-
0024334246
-
Improved retroviral transfer of genes into canine hematopoietic progenitor cells kept in long-term marrow culture
-
Schuening FG, Storb R, Stead RB, et al.: Improved retroviral transfer of genes into canine hematopoietic progenitor cells kept in long-term marrow culture. Blood 1989;74:152-155.
-
(1989)
Blood
, vol.74
, pp. 152-155
-
-
Schuening, F.G.1
Storb, R.2
Stead, R.B.3
-
42
-
-
0028027109
-
Transfer and expression of the human multiple drug resistance gene in human CD34+ cells
-
Ward M, Richardson C, Pioli P, et al.: Transfer and expression of the human multiple drug resistance gene in human CD34+ cells. Blood 1994;84:1408-1414.
-
(1994)
Blood
, vol.84
, pp. 1408-1414
-
-
Ward, M.1
Richardson, C.2
Pioli, P.3
-
43
-
-
0027816238
-
Circumvention of chemotherapy-induced myelosuppression by transfer of the mdr1 gene
-
Boesen JJB, Nooter K, Valerio D: Circumvention of chemotherapy-induced myelosuppression by transfer of the mdr1 gene. Biotherapy 1994;6:291.
-
(1994)
Biotherapy
, vol.6
, pp. 291
-
-
Boesen, J.J.B.1
Nooter, K.2
Valerio, D.3
-
44
-
-
0031972859
-
Phase I trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation
-
Hesdorffer C, Ayello J, Ward M, et al.: Phase I trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation. J Clin Oncol 1998;16:165-172.
-
(1998)
J Clin Oncol
, vol.16
, pp. 165-172
-
-
Hesdorffer, C.1
Ayello, J.2
Ward, M.3
-
45
-
-
0032809319
-
Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients
-
Cowan KH, Moscow JA, Huang H, et al.: Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients. Clin Cancer Res 1999;5:1619-1628.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1619-1628
-
-
Cowan, K.H.1
Moscow, J.A.2
Huang, H.3
-
46
-
-
0342470476
-
Quantitative assessment of retroviral transfer of the human mulitdrug resistance I gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice
-
Schiedimeier B, Kühlcke K, Eckert HG, et al.: Quantitative assessment of retroviral transfer of the human mulitdrug resistance I gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice. Blood 2000;95:1237-1248.
-
(2000)
Blood
, vol.95
, pp. 1237-1248
-
-
Schiedimeier, B.1
Kühlcke, K.2
Eckert, H.G.3
-
47
-
-
0034131481
-
Efficient retrovirus-mediated transfer of the multidrug resistance I gene into autologous human long-term repopulating hematopoietic stem cells
-
Abonour R, Wiliams DA, Einhorn L, et al.: Efficient retrovirus-mediated transfer of the multidrug resistance I gene into autologous human long-term repopulating hematopoietic stem cells. Nat Med 2000;6:652-658.
-
(2000)
Nat Med
, vol.6
, pp. 652-658
-
-
Abonour, R.1
Wiliams, D.A.2
Einhorn, L.3
-
48
-
-
0037051675
-
Genetic protection of repopulating hematopoietic cells with an improved MDR1-retroviurs allows administration of intensified chemotherapy following stem cell transplantation in mice
-
Carpinteiro A, Peinert S, Ostertag W, et al.: Genetic protection of repopulating hematopoietic cells with an improved MDR1-retroviurs allows administration of intensified chemotherapy following stem cell transplantation in mice. Int J Cancer 2002;98:785-792.
-
(2002)
Int J Cancer
, vol.98
, pp. 785-792
-
-
Carpinteiro, A.1
Peinert, S.2
Ostertag, W.3
-
49
-
-
0025799513
-
Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells
-
Chaudhary PM, Roninson IB: Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 1991;66:85.
-
(1991)
Cell
, vol.66
, pp. 85
-
-
Chaudhary, P.M.1
Roninson, I.B.2
-
50
-
-
0027218689
-
Biochemistry of multi-drug resistance mediated by the multidrug transporter
-
Gottesman MM, Pastan I: Biochemistry of multi-drug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993;62:385.
-
(1993)
Annu Rev Biochem
, vol.62
, pp. 385
-
-
Gottesman, M.M.1
Pastan, I.2
-
51
-
-
0027816238
-
Circumvention of chemotherapy-induced myelosuppression by transfer of the mdr1 gene
-
Boesen JJB, Nooter K, Valerio D: Circumvention of chemotherapy-induced myelosuppression by transfer of the mdr1 gene. Biotherapy 1994;6:291.
-
(1994)
Biotherapy
, vol.6
, pp. 291
-
-
Boesen, J.J.B.1
Nooter, K.2
Valerio, D.3
-
52
-
-
0034985885
-
Generation of dual resistance to 4-hydroperoxycyclo-phosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class I gene and a mutated dihydrofolate reductase gene
-
Takebe N, Zhao SC, Adhikari D, et al.: Generation of dual resistance to 4-hydroperoxycyclo-phosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class I gene and a mutated dihydrofolate reductase gene. Mol Ther 2001;3:88-96.
-
(2001)
Mol Ther
, vol.3
, pp. 88-96
-
-
Takebe, N.1
Zhao, S.C.2
Adhikari, D.3
-
53
-
-
0031694564
-
Construction of new retroviral producer cells from adenoviral an retroviral vectors
-
Lin X: Construction of new retroviral producer cells from adenoviral an retroviral vectors. Gene Ther 1998;5:1251-1258.
-
(1998)
Gene Ther
, vol.5
, pp. 1251-1258
-
-
Lin, X.1
-
54
-
-
0025279872
-
Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
-
Miller DG, Adam MA, Miller AD: Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol Cell Biol 1990;10:4239.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 4239
-
-
Miller, D.G.1
Adam, M.A.2
Miller, A.D.3
-
55
-
-
0027158091
-
Integration of murine leukemia virus DNA depends on mitosis
-
Roe T, Reynolds TC, Yu G, et al.: Integration of murine leukemia virus DNA depends on mitosis. EMBO J 1993;12:2099.
-
(1993)
EMBO J
, vol.12
, pp. 2099
-
-
Roe, T.1
Reynolds, T.C.2
Yu, G.3
-
56
-
-
0031964990
-
Retroviral transduction of human CD34+ umbilical cord blood progenitor cells with a mutated dihydrofolate reductase cDNA
-
Flasshove M, Banerjee D, Leonard JP, et al.: Retroviral transduction of human CD34+ umbilical cord blood progenitor cells with a mutated dihydrofolate reductase cDNA. Hum Gene Ther 1998;9:63-71.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 63-71
-
-
Flasshove, M.1
Banerjee, D.2
Leonard, J.P.3
-
57
-
-
0032400850
-
Enhanced retroviral transduction of 5-fluorouracil-resistant human bone marrow (stem) cells using a genetically modified packaging cell line
-
Povey J, Weeratunge N, Marden C, et al.: Enhanced retroviral transduction of 5-fluorouracil-resistant human bone marrow (stem) cells using a genetically modified packaging cell line. Blood 1998;92:4080-4089.
-
(1998)
Blood
, vol.92
, pp. 4080-4089
-
-
Povey, J.1
Weeratunge, N.2
Marden, C.3
-
58
-
-
0028821383
-
HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator
-
Gallay P, Swingler S, Aiken C, et al.: HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator. Cell 1995;80:379-388.
-
(1995)
Cell
, vol.80
, pp. 379-388
-
-
Gallay, P.1
Swingler, S.2
Aiken, C.3
-
59
-
-
0030931963
-
Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector
-
Miyoshi H, Takahashi M, Gage FH, et al.: Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. PNAS 1997;94:10319-10323.
-
(1997)
PNAS
, vol.94
, pp. 10319-10323
-
-
Miyoshi, H.1
Takahashi, M.2
Gage, F.H.3
-
60
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini L, Blomer U, Gallay P, et al.: In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996;272:263-267.
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
-
62
-
-
0027166647
-
Integrins avb3 and avb5 promote adenovirus internalisation but not virus attachment
-
Wickham TJ, Mathias P, Cheresh DA, et al.: Integrins avb3 and avb5 promote adenovirus internalisation but not virus attachment. Cell 1993;73:309-319.
-
(1993)
Cell
, vol.73
, pp. 309-319
-
-
Wickham, T.J.1
Mathias, P.2
Cheresh, D.A.3
-
63
-
-
0030994260
-
Adenovirus type 5 fiber knob binds to MHC class ia2 domain at the surface of human epithelial cells and B lymphoblastoid cell
-
Hong SS, Karayan L, Tournier J, et al.: Adenovirus type 5 fiber knob binds to MHC class ia2 domain at the surface of human epithelial cells and B lymphoblastoid cell. EMBO J 1997;16:2294-2306.
-
(1997)
EMBO J
, vol.16
, pp. 2294-2306
-
-
Hong, S.S.1
Karayan, L.2
Tournier, J.3
-
64
-
-
0031052263
-
Isolation of a common receptor for coxsackie virus B viruses and adenoviruses 2 and 5
-
Bergeison JM, Cunningham JA, Droguett G, et al.: Isolation of a common receptor for coxsackie virus B viruses and adenoviruses 2 and 5. Science 1997;275:1320-1323.
-
(1997)
Science
, vol.275
, pp. 1320-1323
-
-
Bergeison, J.M.1
Cunningham, J.A.2
Droguett, G.3
-
65
-
-
0030271317
-
Strategies for targeted gene therapy
-
Harris JD, Lemoine NR: Strategies for targeted gene therapy. Trends Genet 1996;12:400-404.
-
(1996)
Trends Genet
, vol.12
, pp. 400-404
-
-
Harris, J.D.1
Lemoine, N.R.2
-
66
-
-
0028834822
-
Viral vectors in gene therapy
-
Smith AE: Viral vectors in gene therapy. Ann Rev Microbiol 1995;49:807-838.
-
(1995)
Ann Rev Microbiol
, vol.49
, pp. 807-838
-
-
Smith, A.E.1
-
67
-
-
0029028989
-
Clearance of adenovirus-infected hepatocytes by MHC class 1 restricted CD4+ CTLs in vivo
-
Yang Y, Wilson JM: Clearance of adenovirus-infected hepatocytes by MHC class 1 restricted CD4+ CTLs in vivo. J Immunol 1995;155:2564-2569.
-
(1995)
J Immunol
, vol.155
, pp. 2564-2569
-
-
Yang, Y.1
Wilson, J.M.2
-
68
-
-
0033999338
-
Adenovirus vector-induced expression of the C-X-C chemokine IP-10 is mediated through capsid-dependent activation of NF-κB
-
Borgland SL, Bowen GP, Wong NCW, et al.: Adenovirus vector-induced expression of the C-X-C chemokine IP-10 is mediated through capsid-dependent activation of NF-κB. J Virol 2000;74:3941-3947.
-
(2000)
J Virol
, vol.74
, pp. 3941-3947
-
-
Borgland, S.L.1
Bowen, G.P.2
Wong, N.C.W.3
-
69
-
-
0036202249
-
Adenovirus vector-induced inflammation: Capsid-dependent induction of the C-C chemokine RANTES requires NF-kappa B
-
Bowen GP, Borgland SL, Lam M, et al.: Adenovirus vector-induced inflammation: Capsid-dependent induction of the C-C chemokine RANTES requires NF-kappa B. Hum Gene Ther 2002;13:367-379.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 367-379
-
-
Bowen, G.P.1
Borgland, S.L.2
Lam, M.3
-
70
-
-
0025214094
-
Site-specific integration by adeno-associated virus
-
Kotin RM, Siniscalco M, Samulski RJ, et al.: Site-specific integration by adeno-associated virus. PNAS 1990;87:2211-2215.
-
(1990)
PNAS
, vol.87
, pp. 2211-2215
-
-
Kotin, R.M.1
Siniscalco, M.2
Samulski, R.J.3
-
71
-
-
0030773872
-
Adeno-associated virus vector integration junctions
-
Rutledge EA, Russell DW: Adeno-associated virus vector integration junctions. J Virol 1997;71:8429-8436.
-
(1997)
J Virol
, vol.71
, pp. 8429-8436
-
-
Rutledge, E.A.1
Russell, D.W.2
-
72
-
-
0036227449
-
Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors
-
Zaiss AK, Liu Q, Bowen GP, et al.: Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors. J Virol 2002;76:4580-4590.
-
(2002)
J Virol
, vol.76
, pp. 4580-4590
-
-
Zaiss, A.K.1
Liu, Q.2
Bowen, G.P.3
-
74
-
-
0028036728
-
Induction of antitumor immunity by recombinant vaccinia viruses expressing B7-1 or B7-2 costimulatory molecules
-
Hodge JW, Abrams S, Schlom J, et al.: Induction of antitumor immunity by recombinant vaccinia viruses expressing B7-1 or B7-2 costimulatory molecules. Cancer Res 1994;54:5552-5555.
-
(1994)
Cancer Res
, vol.54
, pp. 5552-5555
-
-
Hodge, J.W.1
Abrams, S.2
Schlom, J.3
-
75
-
-
0034820992
-
Phase 1 study of intravesical vaccinia virus as a vector for gene therapy of bladder cancer
-
Gomella LG, Mastrangelo JM, McCue PA, et al.: Phase 1 study of intravesical vaccinia virus as a vector for gene therapy of bladder cancer. J Urol 2001;166:1291-1295.
-
(2001)
J Urol
, vol.166
, pp. 1291-1295
-
-
Gomella, L.G.1
Mastrangelo, J.M.2
McCue, P.A.3
-
76
-
-
0035665098
-
Gene therapy for head and neck cancer using vaccinia virus expression IL-2 in a murine model, with evidence of immune suppression
-
Qin H, Valentino J, Manna S, et al.: Gene therapy for head and neck cancer using vaccinia virus expression IL-2 in a murine model, with evidence of immune suppression. Mol Ther 2001;4:551-558.
-
(2001)
Mol Ther
, vol.4
, pp. 551-558
-
-
Qin, H.1
Valentino, J.2
Manna, S.3
-
77
-
-
0035893770
-
Systemic cancer therapy with a tumor-selective vaccinia virus mutant lacking thymidine kinase and vaccinia growth factor genes
-
McCart JA, Ward JM, Lee J, et al.: Systemic cancer therapy with a tumor-selective vaccinia virus mutant lacking thymidine kinase and vaccinia growth factor genes. Cancer Res 2001;61:8751-8757.
-
(2001)
Cancer Res
, vol.61
, pp. 8751-8757
-
-
McCart, J.A.1
Ward, J.M.2
Lee, J.3
-
78
-
-
0030789846
-
Potential uses of herpes simplex virus (HSV) vectors for gene therapy of neurological disorders
-
Kennedy PGE: Potential uses of herpes simplex virus (HSV) vectors for gene therapy of neurological disorders. Brain 1997;120:1245-1259.
-
(1997)
Brain
, vol.120
, pp. 1245-1259
-
-
Kennedy, P.G.E.1
-
79
-
-
0028789833
-
Development and application of herpes simplex virus vectors for human gene therapy
-
Glorioso JC, DeLuca NA, Fink DF: Development and application of herpes simplex virus vectors for human gene therapy. Ann Rev Microbiol 1995;49:675-710.
-
(1995)
Ann Rev Microbiol
, vol.49
, pp. 675-710
-
-
Glorioso, J.C.1
DeLuca, N.A.2
Fink, D.F.3
-
80
-
-
0029973972
-
Replication-defective herpes simplex virus vectors for gene transfer in vivo
-
Marconi P, Krisky D, Oligino T, et al.: Replication-defective herpes simplex virus vectors for gene transfer in vivo. Proc Natl Acad Sci USA 1996;93:11319-11320.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11319-11320
-
-
Marconi, P.1
Krisky, D.2
Oligino, T.3
-
81
-
-
0034913116
-
Nonviral vectors in the new millennium: Delivery barriers in gene transfer
-
Nishikawa M, Huang L: Nonviral vectors in the new millennium: Delivery barriers in gene transfer. Hum Gene Ther 2001;12:861-870.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 861-870
-
-
Nishikawa, M.1
Huang, L.2
-
82
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
Wolff JA, Malone RW, Williams P, et al.: Direct gene transfer into mouse muscle in vivo. Science 1990;247:1465-1468.
-
(1990)
Science
, vol.247
, pp. 1465-1468
-
-
Wolff, J.A.1
Malone, R.W.2
Williams, P.3
-
83
-
-
0033948976
-
Naked DNA and adenovrial immuniztions for immunotherapy of prostate cancer: A phase I/II clinical trial
-
Mincheff M, Tchakarov S, Zoubak S, et al.: Naked DNA and adenovrial immuniztions for immunotherapy of prostate cancer: A phase I/II clinical trial. Eur Urol 2000;38:208-217.
-
(2000)
Eur Urol
, vol.38
, pp. 208-217
-
-
Mincheff, M.1
Tchakarov, S.2
Zoubak, S.3
-
84
-
-
0028024919
-
Enhanced gene delivery system and mechanism studies with a novel series of cationic lipid formulations
-
Felgner JH, Kumar R, Sridhar CN, et al.: Enhanced gene delivery system and mechanism studies with a novel series of cationic lipid formulations. J Biol Chem 1994;269:2550-2561.
-
(1994)
J Biol Chem
, vol.269
, pp. 2550-2561
-
-
Felgner, J.H.1
Kumar, R.2
Sridhar, C.N.3
-
85
-
-
0032013106
-
Cationic liposomes in gene delivery
-
Yotsuyanagi T, Hazemoto N: Cationic liposomes in gene delivery. Nippon Rinsho 1998;56:705-712.
-
(1998)
Nippon Rinsho
, vol.56
, pp. 705-712
-
-
Yotsuyanagi, T.1
Hazemoto, N.2
-
86
-
-
0030858780
-
Long term expression of the human alpha1 antitrypson gene in mice employing anionic and cationic liposome vector
-
Alio SF: Long term expression of the human alpha1 antitrypson gene in mice employing anionic and cationic liposome vector. Biochem Pharmacol 1997;54:9-13.
-
(1997)
Biochem Pharmacol
, vol.54
, pp. 9-13
-
-
Alio, S.F.1
-
87
-
-
0025934604
-
Sterically stabilized liposomes: A hypothesis on the molecular origin of the extended circulation times
-
Lasic DD, Martin FJ, Gavizon A, et al.: Sterically stabilized liposomes: A hypothesis on the molecular origin of the extended circulation times. Biochim Biophys Acta 1991;1070:187-192.
-
(1991)
Biochim Biophys Acta
, vol.1070
, pp. 187-192
-
-
Lasic, D.D.1
Martin, F.J.2
Gavizon, A.3
-
88
-
-
0023447237
-
pH sensitive immunoliposomes mediate target-cell-specific delivery and controlled expression of a foreign gene in mouse
-
Wang C, Huang L: pH sensitive immunoliposomes mediate target-cell-specific delivery and controlled expression of a foreign gene in mouse. Proc Natl Acad Sci USA 1987;84:7851-7855.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7851-7855
-
-
Wang, C.1
Huang, L.2
-
89
-
-
0022558795
-
Construction of transferrin-coated liposomes for in vivo transport of exogenous DNA to bone marrow erythroblasts in rabbits
-
Stavridis JC, Deliconstantinos G, Psallidopoulos MC, et al.: Construction of transferrin-coated liposomes for in vivo transport of exogenous DNA to bone marrow erythroblasts in rabbits. Exp Cell Res 1986;164:568-572.
-
(1986)
Exp Cell Res
, vol.164
, pp. 568-572
-
-
Stavridis, J.C.1
Deliconstantinos, G.2
Psallidopoulos, M.C.3
-
90
-
-
0029859574
-
Fusigenic viral liposome for gene therapy in cardiovascular disease
-
Dzau JV, Mann MJ, Morishita R, et al.: Fusigenic viral liposome for gene therapy in cardiovascular disease. Proc Natl Acad Sci USA 1996;93:11421-11425.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11421-11425
-
-
Dzau, J.V.1
Mann, M.J.2
Morishita, R.3
-
91
-
-
0025891831
-
Transferrin-polycation-DNA complexes: The effect of polycations on the structure of the complex and DNA delivery to cells
-
Wagner E, Cotton M, Foisner R, et al.: Transferrin-polycation-DNA complexes: The effect of polycations on the structure of the complex and DNA delivery to cells. Proc Natl Acad Sci USA 1991;88:4255-4259.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 4255-4259
-
-
Wagner, E.1
Cotton, M.2
Foisner, R.3
-
92
-
-
0024343077
-
Targeting genes: Delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo
-
Wu CH, Wilson JM, Wu GY: Targeting genes: Delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo. J Biol Chem 1989;264:16985-16987.
-
(1989)
J Biol Chem
, vol.264
, pp. 16985-16987
-
-
Wu, C.H.1
Wilson, J.M.2
Wu, G.Y.3
-
93
-
-
0027365343
-
Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobin receptor
-
Ferkol T, Kaetzel CS, Davis PB: Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobin receptor. J Clin Invest 1993;92:2394-2400.
-
(1993)
J Clin Invest
, vol.92
, pp. 2394-2400
-
-
Ferkol, T.1
Kaetzel, C.S.2
Davis, P.B.3
-
94
-
-
0026687453
-
Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes
-
Wagner E, Zatloukal K, Cotton M, et al.: Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. PNAS 1992;89:6099-6103.
-
(1992)
PNAS
, vol.89
, pp. 6099-6103
-
-
Wagner, E.1
Zatloukal, K.2
Cotton, M.3
-
95
-
-
0028324325
-
High-efficiency gene transfer employing adenovirus-polylysine-DNA complexes
-
Curiel DT: High-efficiency gene transfer employing adenovirus-polylysine-DNA complexes. Nat Immunol 1994;13:141-146.
-
(1994)
Nat Immunol
, vol.13
, pp. 141-146
-
-
Curiel, D.T.1
-
96
-
-
0028033647
-
Adenovirus-mediated transfection of cultured cells
-
Forsayeth JR, Garcia PD: Adenovirus-mediated transfection of cultured cells. Biotechniques 1994;17:354-358.
-
(1994)
Biotechniques
, vol.17
, pp. 354-358
-
-
Forsayeth, J.R.1
Garcia, P.D.2
-
97
-
-
0026755818
-
High-efficiency rceptor-mediated delivery of small and large (48 kilobase) gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles
-
Cotton M, Wagner E, Zatloukal K, et al.: High-efficiency rceptor-mediated delivery of small and large (48 kilobase) gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles. PNAS 1992;89:6094-6098.
-
(1992)
PNAS
, vol.89
, pp. 6094-6098
-
-
Cotton, M.1
Wagner, E.2
Zatloukal, K.3
-
98
-
-
0028850553
-
Enhancement of liposome-mediated gene transfer into vascular tissue by replication deficient adenovirus
-
Raja-Walia R, Webber J, Naftilan J, et al.: Enhancement of liposome-mediated gene transfer into vascular tissue by replication deficient adenovirus. Gene Ther 1995;2:521-530.
-
(1995)
Gene Ther
, vol.2
, pp. 521-530
-
-
Raja-Walia, R.1
Webber, J.2
Naftilan, J.3
-
99
-
-
0036021907
-
In vivo growth inhibitory effect of iterative wild-type p53 gene transfer in human head and neck carcinoma xenografts using glucosylated polyethylenimine nonviral vector
-
Dolivet G, Merlin JL, Barberi-Heyob M, et al.: In vivo growth inhibitory effect of iterative wild-type p53 gene transfer in human head and neck carcinoma xenografts using glucosylated polyethylenimine nonviral vector. Cancer Gene Ther 2002;9:708-714.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 708-714
-
-
Dolivet, G.1
Merlin, J.L.2
Barberi-Heyob, M.3
-
100
-
-
0036740007
-
Biodegradable, endosome disruptive, and cationic network-type polymer as a highly efficient and nontoxic gene delivery carrier
-
Lim YB, Kim SM, Suh H, et al.: Biodegradable, endosome disruptive, and cationic network-type polymer as a highly efficient and nontoxic gene delivery carrier. Bioconjug Chem 2002;13:952-957.
-
(2002)
Bioconjug Chem
, vol.13
, pp. 952-957
-
-
Lim, Y.B.1
Kim, S.M.2
Suh, H.3
-
101
-
-
0036324712
-
Rapid endo-lysosomal escape of poly (DL-lactide-co-glycolide) nanoparticles: Implications for drug and gene delivery
-
Panyam J, Zhou WZ, Prabha S, et al.: Rapid endo-lysosomal escape of poly (DL-lactide-co-glycolide) nanoparticles: Implications for drug and gene delivery. FASEB J 2002;16:1217-1226.
-
(2002)
FASEB J
, vol.16
, pp. 1217-1226
-
-
Panyam, J.1
Zhou, W.Z.2
Prabha, S.3
|