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Volumn 62, Issue 6, 2003, Pages 464-476

Evolution of the Thymus Size in Response to Physiological and Random Events Throughout Life

Author keywords

Age; Aging; Apoptosis; Chemoattractants; Involution; Pre T cells; Stress; Thymopoiesis

Indexed keywords

PHYSIOLOGICAL MODELS; PHYSIOLOGY; STEM CELLS; T-CELLS; THYMUS;

EID: 0345447486     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jemt.10408     Document Type: Article
Times cited : (61)

References (280)
  • 1
    • 0035007346 scopus 로고    scopus 로고
    • Extrathymic pathways of T-cell differentiation and immunomodulation
    • Abo T. 2001. Extrathymic pathways of T-cell differentiation and immunomodulation. Int Immunopharmacol 1:1261-1273.
    • (2001) Int Immunopharmacol , vol.1 , pp. 1261-1273
    • Abo, T.1
  • 2
    • 0025273465 scopus 로고
    • Interactions between the brain and the immune system
    • Ader R, Felten D, Cohen N. 1990. Interactions between the brain and the immune system. Annu Rev Pharmacol Toxicol 30:561-602.
    • (1990) Annu Rev Pharmacol Toxicol , vol.30 , pp. 561-602
    • Ader, R.1    Felten, D.2    Cohen, N.3
  • 3
    • 0025979007 scopus 로고
    • Developmental regulation of the intrathymic T cell precursor population
    • Adkins B. 1991. Developmental regulation of the intrathymic T cell precursor population. J Immunol 146:1387-1393.
    • (1991) J Immunol , vol.146 , pp. 1387-1393
    • Adkins, B.1
  • 6
    • 0035350807 scopus 로고    scopus 로고
    • Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT
    • Aifantis I, Gounari F, Scorrano L, Borowski C, von Boehmer H. 2001. Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT. Nat Immunol 2:403-409.
    • (2001) Nat Immunol , vol.2 , pp. 403-409
    • Aifantis, I.1    Gounari, F.2    Scorrano, L.3    Borowski, C.4    Von Boehmer, H.5
  • 7
    • 0027443396 scopus 로고
    • IL-1 mRNA expression detected by in situ hybridization and polymerase chain reaction in human thymus and thymoma. Correlation with late T-cell maturation in normal versus neoplastic thymus
    • Aime C, Bristol L, Cohen-Kaminsky S, Berrih-Aknin S, Durum S, Takacs L. 1993. IL-1 mRNA expression detected by in situ hybridization and polymerase chain reaction in human thymus and thymoma. Correlation with late T-cell maturation in normal versus neoplastic thymus. Thymus 22:45-54.
    • (1993) Thymus , vol.22 , pp. 45-54
    • Aime, C.1    Bristol, L.2    Cohen-Kaminsky, S.3    Berrih-Aknin, S.4    Durum, S.5    Takacs, L.6
  • 9
    • 0023813420 scopus 로고
    • Thyroid uptake of gallium in Graves' disease
    • Allard JC, Lee VW, Franklin P. 1988. Thyroid uptake of gallium in Graves' disease. Clin Nucl Med 13:663-666.
    • (1988) Clin Nucl Med , vol.13 , pp. 663-666
    • Allard, J.C.1    Lee, V.W.2    Franklin, P.3
  • 10
    • 0031422695 scopus 로고    scopus 로고
    • Presence of nerve growth factor in the thymus of prenatal, postnatal and pregnant rats
    • Aloe L, Micera A, Bracci-Laudiero L, Vigneti E, Turrini P. 1997. Presence of nerve growth factor in the thymus of prenatal, postnatal and pregnant rats. Thymus 24:221-231.
    • (1997) Thymus , vol.24 , pp. 221-231
    • Aloe, L.1    Micera, A.2    Bracci-Laudiero, L.3    Vigneti, E.4    Turrini, P.5
  • 11
    • 0035253734 scopus 로고    scopus 로고
    • Il-7 and not stem cell factor reverses both the increase in apoptosis and the decline in thymopoiesis seen in aged mice
    • Andrew D, Aspinall R. 2001. Il-7 and not stem cell factor reverses both the increase in apoptosis and the decline in thymopoiesis seen in aged mice. J Immunol 166:1524-1530.
    • (2001) J Immunol , vol.166 , pp. 1524-1530
    • Andrew, D.1    Aspinall, R.2
  • 12
    • 0037012030 scopus 로고    scopus 로고
    • Age-associated thymic atrophy is linked to a decline in IL-7 production
    • Andrew D, Aspinall R. 2002. Age-associated thymic atrophy is linked to a decline in IL-7 production. Exp Gerontol 37:455-463.
    • (2002) Exp Gerontol , vol.37 , pp. 455-463
    • Andrew, D.1    Aspinall, R.2
  • 13
    • 0028335847 scopus 로고
    • Thymic stem cells in mouse bone marrow
    • Antica M, Wu L, Shortman K, Scollay R. 1994. Thymic stem cells in mouse bone marrow. Blood 84:111-117.
    • (1994) Blood , vol.84 , pp. 111-117
    • Antica, M.1    Wu, L.2    Shortman, K.3    Scollay, R.4
  • 14
    • 0028438802 scopus 로고
    • Influence of treadmill exercise on pituitary-adrenal secretions, other blood constituents, and meat quality of sheep
    • Apple JK, Minton JE, Parsons KM, Dikeman ME, Leith DE. 1994. Influence of treadmill exercise on pituitary-adrenal secretions, other blood constituents, and meat quality of sheep. J Anim Sci 72:1306-1314.
    • (1994) J Anim Sci , vol.72 , pp. 1306-1314
    • Apple, J.K.1    Minton, J.E.2    Parsons, K.M.3    Dikeman, M.E.4    Leith, D.E.5
  • 15
    • 0040154621 scopus 로고    scopus 로고
    • Immune-endocrine interactions of the hypothalamus-pituitary-thyroid axis: Integration, communication and homeostasis
    • Armstrong MD, Klein JR. 2001. Immune-endocrine interactions of the hypothalamus-pituitary-thyroid axis: integration, communication and homeostasis. Arch Immunol Ther Exp 49:231-237.
    • (2001) Arch Immunol Ther Exp , vol.49 , pp. 231-237
    • Armstrong, M.D.1    Klein, J.R.2
  • 16
    • 0025810875 scopus 로고
    • Hypothesis: Involution of the thymus with aging: Programmed and beneficial
    • Aronson M. 1991. Hypothesis: involution of the thymus with aging: programmed and beneficial. Thymus 18:7-13.
    • (1991) Thymus , vol.18 , pp. 7-13
    • Aronson, M.1
  • 18
    • 43949160858 scopus 로고
    • A differential-avidity model for T-cell selection
    • Ashton-Rickardt PG, Tonegawa S. 1994. A differential-avidity model for T-cell selection. Immunol Today 15:362-366.
    • (1994) Immunol Today , vol.15 , pp. 362-366
    • Ashton-Rickardt, P.G.1    Tonegawa, S.2
  • 19
    • 0034578448 scopus 로고    scopus 로고
    • Longevity and the immune response
    • Aspinall R. 2000. Longevity and the immune response. Biogerontology 1:273-278.
    • (2000) Biogerontology , vol.1 , pp. 273-278
    • Aspinall, R.1
  • 20
    • 0033985021 scopus 로고    scopus 로고
    • Immunosenescence: Potential causes and strategies for reversal
    • Aspinall R, Andrew D. 2000a. Immunosenescence: potential causes and strategies for reversal. Biochem Soc Trans 28:250-254.
    • (2000) Biochem Soc Trans , vol.28 , pp. 250-254
    • Aspinall, R.1    Andrew, D.2
  • 21
    • 0033954359 scopus 로고    scopus 로고
    • Thymic atrophy in the mouse is a soluble problem of the thymic environment
    • Aspinall R, Andrew D. 2000b. Thymic atrophy in the mouse is a soluble problem of the thymic environment. Vaccine 18:1629-1637.
    • (2000) Vaccine , vol.18 , pp. 1629-1637
    • Aspinall, R.1    Andrew, D.2
  • 22
    • 0035885872 scopus 로고    scopus 로고
    • Age-associated thymic atrophy is not associated with a deficiency in the CD44(+)CD25(-)-CD3(-)CD4(-)CD8(-) thymocyte population
    • Aspinall R, Andrew D. 2001a. Age-associated thymic atrophy is not associated with a deficiency in the CD44(+)CD25(-)-CD3(-)CD4(-)CD8(-) thymocyte population. Cell Immunol 212:150-157.
    • (2001) Cell Immunol , vol.212 , pp. 150-157
    • Aspinall, R.1    Andrew, D.2
  • 23
    • 0034813420 scopus 로고    scopus 로고
    • Gender-related differences in the rates of age associated thymic atrophy
    • Aspinall R, Andrew D. 2001b. Gender-related differences in the rates of age associated thymic atrophy. Dev Immunol 8:95-106.
    • (2001) Dev Immunol , vol.8 , pp. 95-106
    • Aspinall, R.1    Andrew, D.2
  • 25
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis
    • Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M. 1995. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 270:286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 26
    • 0028558966 scopus 로고
    • The mind and the immune system
    • Ballieux RE. 1994. The mind and the immune system. Theor Med 15:387-395.
    • (1994) Theor Med , vol.15 , pp. 387-395
    • Ballieux, R.E.1
  • 28
    • 0025317893 scopus 로고
    • The influence of cold or isolation stress on resistance of mice to West Nile virus encephalitis
    • Ben-Nathan D, Feuerstein G. 1990. The influence of cold or isolation stress on resistance of mice to West Nile virus encephalitis. Experientia 46:285-290.
    • (1990) Experientia , vol.46 , pp. 285-290
    • Ben-Nathan, D.1    Feuerstein, G.2
  • 30
    • 0032765086 scopus 로고    scopus 로고
    • Age- and disease-related decline in immune function: An opportunity for "thymus-boosting" therapies
    • Berthiaume F, Aparicio CL, Eungdamrong J, Yarmush ML. 1999. Age- and disease-related decline in immune function: an opportunity for "thymus-boosting" therapies. Tissue Eng 5:499-514.
    • (1999) Tissue Eng , vol.5 , pp. 499-514
    • Berthiaume, F.1    Aparicio, C.L.2    Eungdamrong, J.3    Yarmush, M.L.4
  • 31
    • 0022530255 scopus 로고
    • Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones
    • Besedovsky H, del Rey A, Sorkin E, Dinarello CA. 1986. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science 233:652-654.
    • (1986) Science , vol.233 , pp. 652-654
    • Besedovsky, H.1    Del Rey, A.2    Sorkin, E.3    Dinarello, C.A.4
  • 32
    • 0024836456 scopus 로고
    • Mechanism of virus-induced stimulation of the hypothalamus-pituitary-adrenal axis
    • Besedovsky HO, del Rey A. 1989. Mechanism of virus-induced stimulation of the hypothalamus-pituitary-adrenal axis. J Steroid Biochem 34:235-239.
    • (1989) J Steroid Biochem , vol.34 , pp. 235-239
    • Besedovsky, H.O.1    Del Rey, A.2
  • 33
    • 0021398972 scopus 로고
    • The immune system as a sensory organ
    • Blalock JE. 1984. The immune system as a sensory organ. J Immunol 132:1067-1070.
    • (1984) J Immunol , vol.132 , pp. 1067-1070
    • Blalock, J.E.1
  • 34
    • 0021865557 scopus 로고
    • Proopiomelanocortin-derived peptides in the immune system
    • Blalock JE. 1985. Proopiomelanocortin-derived peptides in the immune system. Clin Endocrinol (Oxf) 22:823-827.
    • (1985) Clin Endocrinol (Oxf) , vol.22 , pp. 823-827
    • Blalock, J.E.1
  • 35
    • 0023822409 scopus 로고
    • Production of neuroendocrine peptide hormones by the immune system
    • Blalock JE. 1988. Production of neuroendocrine peptide hormones by the immune system. Prog Allergy 43:1-13.
    • (1988) Prog Allergy , vol.43 , pp. 1-13
    • Blalock, J.E.1
  • 36
    • 0024532757 scopus 로고
    • A molecular basis for bidirectional communication between the immune and neuroendocrine systems
    • Blalock JE. 1989. A molecular basis for bidirectional communication between the immune and neuroendocrine systems. Physiol Rev 69:1-32.
    • (1989) Physiol Rev , vol.69 , pp. 1-32
    • Blalock, J.E.1
  • 37
    • 0028633539 scopus 로고
    • Shared ligands and receptors as a molecular mechanism for communication between the immune and neuroendocrine systems
    • Blalock JE. 1994a. Shared ligands and receptors as a molecular mechanism for communication between the immune and neuroendocrine systems. Ann N Y Acad Sci 741:292-298.
    • (1994) Ann N Y Acad Sci , vol.741 , pp. 292-298
    • Blalock, J.E.1
  • 38
    • 43949157849 scopus 로고
    • The syntax of immune-neuroendocrine communication
    • Blalock JE. 1994b. The syntax of immune-neuroendocrine communication. Immunol Today 15:504-511.
    • (1994) Immunol Today , vol.15 , pp. 504-511
    • Blalock, J.E.1
  • 39
    • 0032042138 scopus 로고    scopus 로고
    • Beta-endorphin in immune cells
    • Blalock JE. 1998. Beta-endorphin in immune cells. Immunol Today 19:191-192.
    • (1998) Immunol Today , vol.19 , pp. 191-192
    • Blalock, J.E.1
  • 40
    • 0032787654 scopus 로고    scopus 로고
    • Proopiomelanocortin and the immune-neuroendocrine connection
    • Blalock JE. 1999. Proopiomelanocortin and the immune-neuroendocrine connection. Ann NY Acad Sci 885:161-172.
    • (1999) Ann NY Acad Sci , vol.885 , pp. 161-172
    • Blalock, J.E.1
  • 41
    • 0037128643 scopus 로고    scopus 로고
    • Harnessing a neural-immune circuit to control inflammation and shock
    • Blalock JE. 2002. Harnessing a neural-immune circuit to control inflammation and shock. J Exp Med 195:F25-28.
    • (2002) J Exp Med , vol.195
    • Blalock, J.E.1
  • 42
    • 0022348021 scopus 로고
    • Peptide hormones shared by the neuroendocrine and immunologic systems
    • Blalock JE, Harbour-McMenamin D, Smith EM. 1985. Peptide hormones shared by the neuroendocrine and immunologic systems. J Immunol 135:858s-861s.
    • (1985) J Immunol , vol.135
    • Blalock, J.E.1    Harbour-McMenamin, D.2    Smith, E.M.3
  • 43
    • 0031569460 scopus 로고    scopus 로고
    • Prethymic CD34+ progenitors capable of developing into T cells are not committed to the T cell lineage
    • Blom B, Res P, Noteboom E, Weijer K, Spits H. 1997. Prethymic CD34+ progenitors capable of developing into T cells are not committed to the T cell lineage. J Immunol 158:3571-3577.
    • (1997) J Immunol , vol.158 , pp. 3571-3577
    • Blom, B.1    Res, P.2    Noteboom, E.3    Weijer, K.4    Spits, H.5
  • 44
    • 0031903866 scopus 로고    scopus 로고
    • T cell precursors in man and mice
    • Blom B, Res PC, Spits H. 1998. T cell precursors in man and mice. Crit Rev Immunol 18:371-388.
    • (1998) Crit Rev Immunol , vol.18 , pp. 371-388
    • Blom, B.1    Res, P.C.2    Spits, H.3
  • 45
    • 0014872433 scopus 로고
    • Characteristics of the immunocompetent cells in the mouse thymus: Cell population changes during cortisone-induced atrophy and subsequent regeneration
    • Blomgren H, Andersson B. 1970. Characteristics of the immunocompetent cells in the mouse thymus: cell population changes during cortisone-induced atrophy and subsequent regeneration. Cell Immunol 1:545-560.
    • (1970) Cell Immunol , vol.1 , pp. 545-560
    • Blomgren, H.1    Andersson, B.2
  • 46
    • 0030845378 scopus 로고    scopus 로고
    • Dendritic type, accessory cells within the mammalian thymic microenvironment. Antigen presentation in the dendritic neuro-endocrine-immune cellular network
    • Bodey B, Bodey B, Jr., Kaiser HE. 1997a. Dendritic type, accessory cells within the mammalian thymic microenvironment. Antigen presentation in the dendritic neuro-endocrine-immune cellular network. In Vivo 11:351-370.
    • (1997) In Vivo , vol.11 , pp. 351-370
    • Bodey, B.1    Bodey Jr., B.2    Kaiser, H.E.3
  • 47
    • 0030731484 scopus 로고    scopus 로고
    • Involution of the mammalian thymus, one of the leading regulators of aging
    • Bodey B, Bodey B, Jr., Siegel SE, Kaiser HE. 1997b. Involution of the mammalian thymus, one of the leading regulators of aging. In Vivo 11:421-440.
    • (1997) In Vivo , vol.11 , pp. 421-440
    • Bodey, B.1    Bodey Jr., B.2    Siegel, S.E.3    Kaiser, H.E.4
  • 48
    • 0032408385 scopus 로고    scopus 로고
    • The role of zinc in pre- and postnatal mammalian thymic immunohistogenesis
    • Bodey B, Bodey B, Jr., Siegel SE, Kaiser HE. 1998. The role of zinc in pre- and postnatal mammalian thymic immunohistogenesis. In Vivo 12:695-722.
    • (1998) In Vivo , vol.12 , pp. 695-722
    • Bodey, B.1    Bodey Jr., B.2    Siegel, S.E.3    Kaiser, H.E.4
  • 49
    • 0035984960 scopus 로고    scopus 로고
    • Restoration of the thymic cellular microenvironment following autologous bone marrow transplantation
    • Bodey B, Siegel SE, Kaiser HE. 2002. Restoration of the thymic cellular microenvironment following autologous bone marrow transplantation. In Vivo 16:127-140.
    • (2002) In Vivo , vol.16 , pp. 127-140
    • Bodey, B.1    Siegel, S.E.2    Kaiser, H.E.3
  • 50
    • 0026604838 scopus 로고
    • Restraint and sound stress reduce the in vitro migration of prethymic stem cells to thymus supernatant
    • Bomberger CE, Haar JL. 1992. Restraint and sound stress reduce the in vitro migration of prethymic stem cells to thymus supernatant. Thymus 19:111-115.
    • (1992) Thymus , vol.19 , pp. 111-115
    • Bomberger, C.E.1    Haar, J.L.2
  • 51
    • 0031947287 scopus 로고    scopus 로고
    • Thymic myoid cell turnover in myasthenia gravis patients and in normal controls
    • Bornemann A, Kirchner T. 1998. Thymic myoid cell turnover in myasthenia gravis patients and in normal controls. Virchows Arch 432:357-361.
    • (1998) Virchows Arch , vol.432 , pp. 357-361
    • Bornemann, A.1    Kirchner, T.2
  • 53
    • 0033793923 scopus 로고    scopus 로고
    • T-cell development and function: A down under experience
    • Boyd R, Chidgey A. 2000. T-cell development and function: a down under experience. Immunol Today 21:472-474.
    • (2000) Immunol Today , vol.21 , pp. 472-474
    • Boyd, R.1    Chidgey, A.2
  • 54
    • 0026067468 scopus 로고
    • Towards an integrated view of thymopoiesis
    • Boyd RL, Hugo P. 1991. Towards an integrated view of thymopoiesis. Immunol Today 12:71-79.
    • (1991) Immunol Today , vol.12 , pp. 71-79
    • Boyd, R.L.1    Hugo, P.2
  • 59
    • 0000048881 scopus 로고
    • The emergency function of the adrenal medula in pain and major emotions
    • Cannon WB. 1914. The emergency function of the adrenal medula in pain and major emotions. Am J Physiol 33:356.
    • (1914) Am J Physiol , vol.33 , pp. 356
    • Cannon, W.B.1
  • 61
    • 0022453509 scopus 로고
    • The embryonic thymus produces chemotactic peptides involved in the homing of hemopoietic precursors
    • Champion S, Imhof BA, Savagner P, Thiery JP. 1986. The embryonic thymus produces chemotactic peptides involved in the homing of hemopoietic precursors. Cell 44:781-790.
    • (1986) Cell , vol.44 , pp. 781-790
    • Champion, S.1    Imhof, B.A.2    Savagner, P.3    Thiery, J.P.4
  • 63
    • 0034856327 scopus 로고    scopus 로고
    • Thymic stromal cells and positive selection
    • Chidgey AP, Boyd RL. 2001. Thymic stromal cells and positive selection. Apmis 109:481-492.
    • (2001) Apmis , vol.109 , pp. 481-492
    • Chidgey, A.P.1    Boyd, R.L.2
  • 64
    • 0018653698 scopus 로고
    • Ultrastructure of the thymus of the hedgehog (Erinaceus europaeus) during wakefulness, hibernation and various phases of reawakening
    • Cirri Borghi MB, Arbi Riccardi R. 1979. Ultrastructure of the thymus of the hedgehog (Erinaceus europaeus) during wakefulness, hibernation and various phases of reawakening. Arch Ital Anat Embriol 84:207-243.
    • (1979) Arch Ital Anat Embriol , vol.84 , pp. 207-243
    • Cirri Borghi, M.B.1    Arbi Riccardi, R.2
  • 65
    • 0028036930 scopus 로고
    • The thymus in pregnancy: The interplay of neural, endocrine and immune influences
    • Clarke AG, Kendall MD. 1994. The thymus in pregnancy: the interplay of neural, endocrine and immune influences. Immunol Today 15:545-551.
    • (1994) Immunol Today , vol.15 , pp. 545-551
    • Clarke, A.G.1    Kendall, M.D.2
  • 66
    • 0029856924 scopus 로고    scopus 로고
    • Regulation of an extrathymic T-cell development pathway by oncostatin M
    • Clegg CH, Rulffes JT, Wallace PM, Haugen HS. 1996. Regulation of an extrathymic T-cell development pathway by oncostatin M. Nature 384:261-263.
    • (1996) Nature , vol.384 , pp. 261-263
    • Clegg, C.H.1    Rulffes, J.T.2    Wallace, P.M.3    Haugen, H.S.4
  • 67
    • 0019152891 scopus 로고
    • Progressively elevated levels of biologically active (free) cortisol during pregnancy by a direct radioimmunological assay of diffusible cortisol in an equilibrium dialysis system
    • Clerico A, Del Chicca MG, Ferdeghini M, Ghione S, Materazzi F. 1980a. Progressively elevated levels of biologically active (free) cortisol during pregnancy by a direct radioimmunological assay of diffusible cortisol in an equilibrium dialysis system. J Endocrinol Invest 3:185-187.
    • (1980) J Endocrinol Invest , vol.3 , pp. 185-187
    • Clerico, A.1    Del Chicca, M.G.2    Ferdeghini, M.3    Ghione, S.4    Materazzi, F.5
  • 68
    • 0019200150 scopus 로고
    • Radioimmunological determination of apparent free progesterone concentration in plasma samples of pregnant and non-pregnant women
    • Clerico A, Del Chicca MG, Strigini F, Melis GB, Paoletti AM, Mariani G, Fioretti P. 1980b. Radioimmunological determination of apparent free progesterone concentration in plasma samples of pregnant and non-pregnant women. Clin Chim Acta 105:141-144.
    • (1980) Clin Chim Acta , vol.105 , pp. 141-144
    • Clerico, A.1    Del Chicca, M.G.2    Strigini, F.3    Melis, G.B.4    Paoletti, A.M.5    Mariani, G.6    Fioretti, P.7
  • 69
    • 0028676101 scopus 로고
    • Apoptosis: Physiologic cell death
    • Cohen JJ. 1994. Apoptosis: physiologic cell death. J Lab Clin Med 124:761-765.
    • (1994) J Lab Clin Med , vol.124 , pp. 761-765
    • Cohen, J.J.1
  • 71
    • 0023655179 scopus 로고
    • Identification of a glucocorticoid-induced nuclease in thymocytes. A potential "lysis gene" product
    • Compton MM, Cidlowski JA. 1987. Identification of a glucocorticoid-induced nuclease in thymocytes. A potential "lysis gene" product. J Biol Chem 262:8288-8292.
    • (1987) J Biol Chem , vol.262 , pp. 8288-8292
    • Compton, M.M.1    Cidlowski, J.A.2
  • 72
    • 17344383566 scopus 로고
    • Physiological programmed cell death in thymocytes is induced by physical stress (exercise)
    • Concordet JP, Ferry A. 1993. Physiological programmed cell death in thymocytes is induced by physical stress (exercise). Am J Physiol 265:C626-629.
    • (1993) Am J Physiol , vol.265
    • Concordet, J.P.1    Ferry, A.2
  • 74
    • 0021084496 scopus 로고
    • A new concept of Pierre Robin syndrome and disease: Dysneurulation of the rhombencephalon
    • Couly G. 1983. A new concept of Pierre Robin syndrome and disease: dysneurulation of the rhombencephalon. Rev Stomatol Chir Maxillofac 84:225-232.
    • (1983) Rev Stomatol Chir Maxillofac , vol.84 , pp. 225-232
    • Couly, G.1
  • 75
    • 0020526754 scopus 로고
    • Di George syndrome, exemplary rhomboencephalic neurocristopathy
    • Couly G, Lagrue A, Griscelli C. 1983. Di George syndrome, exemplary rhomboencephalic neurocristopathy. Rev Stomatol Chir Maxillofac 84:103-108.
    • (1983) Rev Stomatol Chir Maxillofac , vol.84 , pp. 103-108
    • Couly, G.1    Lagrue, A.2    Griscelli, C.3
  • 76
    • 0030602798 scopus 로고    scopus 로고
    • The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte
    • Crompton T, Gilmour KC, Owen MJ. 1996. The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte. Cell 86:243-251.
    • (1996) Cell , vol.86 , pp. 243-251
    • Crompton, T.1    Gilmour, K.C.2    Owen, M.J.3
  • 77
    • 0035076986 scopus 로고    scopus 로고
    • Thymic export in aged sheep: A continuous role for the thymus throughout pre- and postnatal life
    • Cunningham CP, Kimpton WG, Holder JE, Cahill RN. 2001. Thymic export in aged sheep: a continuous role for the thymus throughout pre- and postnatal life. Eur J Immunol 31:802-811.
    • (2001) Eur J Immunol , vol.31 , pp. 802-811
    • Cunningham, C.P.1    Kimpton, W.G.2    Holder, J.E.3    Cahill, R.N.4
  • 78
    • 0028020382 scopus 로고
    • Control of thymus physiology by peptidic hormones and neuropeptides
    • Dardenne M, Savino W. 1994. Control of thymus physiology by peptidic hormones and neuropeptides. Immunol Today 15:518-523.
    • (1994) Immunol Today , vol.15 , pp. 518-523
    • Dardenne, M.1    Savino, W.2
  • 80
    • 0021945837 scopus 로고
    • Fetal thymus organ culture as an in vitro model for the toxicity of 23,7,8-tetrachlorodibenzo-p-dioxin and its congeners
    • Dencker L, Hassoun E, d'Argy R, Alm G. 1985. Fetal thymus organ culture as an in vitro model for the toxicity of 23,7,8-tetrachlorodibenzo-p-dioxin and its congeners. Mol Pharmacol 27:133-140.
    • (1985) Mol Pharmacol , vol.27 , pp. 133-140
    • Dencker, L.1    Hassoun, E.2    D'Argy, R.3    Alm, G.4
  • 81
    • 0024588320 scopus 로고
    • Characterization of rat T cell precursors sorted by chemotactic migration toward thymotaxin
    • Deugnier MA, Imhof BA, Bauvois B, Dunon D, Denoyelle M, Thiery JP. 1989. Characterization of rat T cell precursors sorted by chemotactic migration toward thymotaxin. Cell 56:1073-1083.
    • (1989) Cell , vol.56 , pp. 1073-1083
    • Deugnier, M.A.1    Imhof, B.A.2    Bauvois, B.3    Dunon, D.4    Denoyelle, M.5    Thiery, J.P.6
  • 82
    • 2342668267 scopus 로고    scopus 로고
    • Time-course of the murine lymphoid tissue involution during and following stressor exposure
    • Domínguez-Gerpe L, Rey-Méndez M. 1997. Time-course of the murine lymphoid tissue involution during and following stressor exposure. Life Sci 61:1019-1027.
    • (1997) Life Sci , vol.61 , pp. 1019-1027
    • Domínguez-Gerpe, L.1    Rey-Méndez, M.2
  • 83
    • 0031806892 scopus 로고    scopus 로고
    • Age-related changes in primary and secondary immune organs of the mouse
    • Domínguez-Gerpe L, Rey-Méndez M. 1998a. Age-related changes in primary and secondary immune organs of the mouse. Immunol Invest 27:153-165.
    • (1998) Immunol Invest , vol.27 , pp. 153-165
    • Domínguez-Gerpe, L.1    Rey-Méndez, M.2
  • 84
    • 0032516711 scopus 로고    scopus 로고
    • Modulation of stress-induced murine lymphoid tissue involution by age, sex and strain: Role of bone marrow
    • Domínguez-Gerpe L, Rey-Méndez M. 1998b. Modulation of stress-induced murine lymphoid tissue involution by age, sex and strain: role of bone marrow. Mech Ageing Dev 104:195-205.
    • (1998) Mech Ageing Dev , vol.104 , pp. 195-205
    • Domínguez-Gerpe, L.1    Rey-Méndez, M.2
  • 85
    • 0033659043 scopus 로고    scopus 로고
    • Role of pre-T cells and chemoattractants on stress-associated thymus involution
    • Domínguez-Gerpe L, Rey-Méndez M. 2000. Role of pre-T cells and chemoattractants on stress-associated thymus involution. Scand J Immunol 52:470-476.
    • (2000) Scand J Immunol , vol.52 , pp. 470-476
    • Domínguez-Gerpe, L.1    Rey-Méndez, M.2
  • 88
    • 0027370623 scopus 로고
    • Frequency analysis of the T cell precursors in the thymus
    • Dou YM, Germeraad WT, Gyotoku J, Katsura Y. 1993. Frequency analysis of the T cell precursors in the thymus. Cell Immunol 150:269-280.
    • (1993) Cell Immunol , vol.150 , pp. 269-280
    • Dou, Y.M.1    Germeraad, W.T.2    Gyotoku, J.3    Katsura, Y.4
  • 90
    • 0033951594 scopus 로고    scopus 로고
    • Evidence for thymic function in the elderly
    • Douek DC, Koup RA. 2000. Evidence for thymic function in the elderly. Vaccine 18:1638-1641.
    • (2000) Vaccine , vol.18 , pp. 1638-1641
    • Douek, D.C.1    Koup, R.A.2
  • 91
    • 0023119429 scopus 로고
    • Evidence of neuro-immunologic interactions: Cyclosporine modifies opiate withdrawal by effects on the brain and immune components
    • Dougherty PM, Aronowski J, Drath D, Dafny N. 1987. Evidence of neuro-immunologic interactions: cyclosporine modifies opiate withdrawal by effects on the brain and immune components. J Neuroimmunol 13:331-342.
    • (1987) J Neuroimmunol , vol.13 , pp. 331-342
    • Dougherty, P.M.1    Aronowski, J.2    Drath, D.3    Dafny, N.4
  • 92
    • 0025054437 scopus 로고
    • Microiontophoretic application of muramyl-dipeptide upon single cortical, hippocampal and hypothalamic neurons in rats
    • Dougherty PM, Dafny N. 1990. Microiontophoretic application of muramyl-dipeptide upon single cortical, hippocampal and hypothalamic neurons in rats. Neuropharmacology 29:973-981.
    • (1990) Neuropharmacology , vol.29 , pp. 973-981
    • Dougherty, P.M.1    Dafny, N.2
  • 93
    • 84958685199 scopus 로고
    • Effects of hormones on lymphatic tissue
    • Dougherty TF. 1952. Effects of hormones on lymphatic tissue. Physiol Rev 32:379-495.
    • (1952) Physiol Rev , vol.32 , pp. 379-495
    • Dougherty, T.F.1
  • 94
    • 0025146574 scopus 로고
    • T cell precursor migration towards beta 2-microglobulin is involved in thymus colonization of chicken embryos
    • Dunon D, Kaufman J, Salomonsen J, Skjoedt K, Vainio O, Thiery JP, Imhof BA. 1990. T cell precursor migration towards beta 2-microglobulin is involved in thymus colonization of chicken embryos. Embo J 9:3315-3322.
    • (1990) Embo J , vol.9 , pp. 3315-3322
    • Dunon, D.1    Kaufman, J.2    Salomonsen, J.3    Skjoedt, K.4    Vainio, O.5    Thiery, J.P.6    Imhof, B.A.7
  • 95
    • 0027396168 scopus 로고
    • Mechanisms of thymus homing
    • Dunon D, Imhof BA. 1993. Mechanisms of thymus homing. Blood 81:1-8.
    • (1993) Blood , vol.81 , pp. 1-8
    • Dunon, D.1    Imhof, B.A.2
  • 97
    • 0020807815 scopus 로고
    • Changes in the structure of the lymphoid organs of rats during prolonged hypokinesia
    • Durnova GN, Kaplanskii AS. 1983. Changes in the structure of the lymphoid organs of rats during prolonged hypokinesia. Arkh Anat Gistol Embriol 85:17-21.
    • (1983) Arkh Anat Gistol Embriol , vol.85 , pp. 17-21
    • Durnova, G.N.1    Kaplanskii, A.S.2
  • 98
    • 0028802002 scopus 로고
    • Role of the thymus in the physiopathology of myasthenia
    • Eymard B, Berrih-Aknin S. 1995. Role of the thymus in the physiopathology of myasthenia. Rev Neurol (Paris) 151:6-15.
    • (1995) Rev Neurol (Paris) , vol.151 , pp. 6-15
    • Eymard, B.1    Berrih-Aknin, S.2
  • 100
    • 0026127478 scopus 로고
    • Neurotransmitter signaling of cells of the immune system: Important progress major gaps
    • Felten DL. 1991. Neurotransmitter signaling of cells of the immune system: important progress major gaps. Brain Behav Immun 5:2-8.
    • (1991) Brain Behav Immun , vol.5 , pp. 2-8
    • Felten, D.L.1
  • 101
    • 0024149985 scopus 로고
    • Sympathetic noradrenergic innervation of immune organs
    • Felten DL, Felten SY. 1988. Sympathetic noradrenergic innervation of immune organs. Brain Behav Immun 2:293-300.
    • (1988) Brain Behav Immun , vol.2 , pp. 293-300
    • Felten, D.L.1    Felten, S.Y.2
  • 104
    • 0027311080 scopus 로고
    • Effect of lithium salts on the microstructure of the thymus and on vitamin C content in some lymphatic organs, the liver and suprarenal glands in F1 mouse crosses (CBA x C57BL)
    • Ficek W, Lesniewska J, Mrowca D. 1993. Effect of lithium salts on the microstructure of the thymus and on vitamin C content in some lymphatic organs, the liver and suprarenal glands in F1 mouse crosses (CBA x C57BL). Toxicol Ind Health 9:485-491.
    • (1993) Toxicol Ind Health , vol.9 , pp. 485-491
    • Ficek, W.1    Lesniewska, J.2    Mrowca, D.3
  • 106
    • 0027223693 scopus 로고
    • Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations
    • Gagnerault MC, Touraine P, Savino W, Kelly PA, Dardenne M. 1993. Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations. J Immunol 150:5673-5681.
    • (1993) J Immunol , vol.150 , pp. 5673-5681
    • Gagnerault, M.C.1    Touraine, P.2    Savino, W.3    Kelly, P.A.4    Dardenne, M.5
  • 107
    • 0015444191 scopus 로고
    • The thymus of marmots: Spontaneous, natural seasonal thymectomy?
    • Galletti G, Cavallari A. 1972. The thymus of marmots: spontaneous, natural seasonal thymectomy? Acta Anat 83:593-605.
    • (1972) Acta Anat , vol.83 , pp. 593-605
    • Galletti, G.1    Cavallari, A.2
  • 110
    • 0029895686 scopus 로고    scopus 로고
    • Thymic involution with ageing: Obsolescence or good housekeeping?
    • George AJ, Ritter MA. 1996. Thymic involution with ageing: obsolescence or good housekeeping? Immunol Today 17:267-272.
    • (1996) Immunol Today , vol.17 , pp. 267-272
    • George, A.J.1    Ritter, M.A.2
  • 112
    • 0023355361 scopus 로고
    • Stress-associated depression in cellular immunity: Implications for acquired immune deficiency syndrome (AIDS)
    • Glaser R, Kiecolt-Glaser J. 1987. Stress-associated depression in cellular immunity: implications for acquired immune deficiency syndrome (AIDS). Brain Behav Immun 1:107-112.
    • (1987) Brain Behav Immun , vol.1 , pp. 107-112
    • Glaser, R.1    Kiecolt-Glaser, J.2
  • 113
    • 0034509630 scopus 로고    scopus 로고
    • Stress-free T-cell development: Glucocorticoids are not obligatory
    • Godfrey DI, Purton JF, Boyd RL, Cole TJ. 2000. Stress-free T-cell development: glucocorticoids are not obligatory. Immunol Today 21:606-611.
    • (2000) Immunol Today , vol.21 , pp. 606-611
    • Godfrey, D.I.1    Purton, J.F.2    Boyd, R.L.3    Cole, T.J.4
  • 116
    • 0002971238 scopus 로고
    • The lymphatic system
    • Goss JA, editor. Philadelphia: Lea and Febiger
    • Gray H. 1973. The lymphatic system. In: Goss JA, editor. Anatomy of the human body. Philadelphia: Lea and Febiger. p 772-773.
    • (1973) Anatomy of the Human Body , pp. 772-773
    • Gray, H.1
  • 117
    • 0022451971 scopus 로고
    • Reappearance of the thymus in old rats after orchidectomy: Inhibition of regeneration by testosterone
    • Greenstein BD, Fitzpatrick FT, Adcock IM, Kendall MD, Wheeler MJ. 1986. Reappearance of the thymus in old rats after orchidectomy: inhibition of regeneration by testosterone. J Endocrinol 110:417-422.
    • (1986) J Endocrinol , vol.110 , pp. 417-422
    • Greenstein, B.D.1    Fitzpatrick, F.T.2    Adcock, I.M.3    Kendall, M.D.4    Wheeler, M.J.5
  • 118
    • 0023134048 scopus 로고
    • Regeneration of the thymus in old male rats treated with a stable analogue of LHRH
    • Greenstein BD, Fitzpatrick FT, Kendall MD, Wheeler MJ. 1987. Regeneration of the thymus in old male rats treated with a stable analogue of LHRH. J Endocrinol 112:345-350.
    • (1987) J Endocrinol , vol.112 , pp. 345-350
    • Greenstein, B.D.1    Fitzpatrick, F.T.2    Kendall, M.D.3    Wheeler, M.J.4
  • 119
    • 84982342478 scopus 로고
    • Regeneration of the involuted thymus after adrenalectomy
    • Gregoire C. 1943. Regeneration of the involuted thymus after adrenalectomy. J Morphol 72:239-261.
    • (1943) J Morphol , vol.72 , pp. 239-261
    • Gregoire, C.1
  • 120
    • 0031171320 scopus 로고    scopus 로고
    • Changes in the aging immune system
    • Grubeck-Loebenstein B. 1997. Changes in the aging immune system. Biologicals 25:205-208.
    • (1997) Biologicals , vol.25 , pp. 205-208
    • Grubeck-Loebenstein, B.1
  • 121
    • 0022511978 scopus 로고
    • Hypertensive potency of 18-oxocortisol in the rat
    • Hall CE, Gomez-Sanchez CE. 1986. Hypertensive potency of 18-oxocortisol in the rat. Hypertension 8:317-322.
    • (1986) Hypertension , vol.8 , pp. 317-322
    • Hall, C.E.1    Gomez-Sanchez, C.E.2
  • 124
    • 0031759778 scopus 로고    scopus 로고
    • The human thymus. A chimeric organ comprised of central and peripheral lymphoid components
    • Haynes BF, Hale LP. 1998. The human thymus. A chimeric organ comprised of central and peripheral lymphoid components. Immunol Res 18:61-78.
    • (1998) Immunol Res , vol.18 , pp. 61-78
    • Haynes, B.F.1    Hale, L.P.2
  • 125
    • 0028059474 scopus 로고
    • Understanding the mechanism of the age-change of thymic function to promote T cell differentiation
    • Hirokawa K, Utsuyama M, Kasai M, Kurashima C, Ishijima S, Zeng YX. 1994. Understanding the mechanism of the age-change of thymic function to promote T cell differentiation. Immunol Lett 40:269-277.
    • (1994) Immunol Lett , vol.40 , pp. 269-277
    • Hirokawa, K.1    Utsuyama, M.2    Kasai, M.3    Kurashima, C.4    Ishijima, S.5    Zeng, Y.X.6
  • 127
    • 0029000748 scopus 로고
    • Molecular alterations in the aging immune system
    • Hodes RJ. 1995. Molecular alterations in the aging immune system. J Exp Med 182:1-3.
    • (1995) J Exp Med , vol.182 , pp. 1-3
    • Hodes, R.J.1
  • 128
    • 0023140914 scopus 로고
    • Thymic hyperplasia. I. True thymic hyperplasia. Review of the literature
    • Hofmann WJ, Moller P, Otto HF. 1987. Thymic hyperplasia. I. True thymic hyperplasia. Review of the literature. Klin Wochenschr 65:49-52.
    • (1987) Klin Wochenschr , vol.65 , pp. 49-52
    • Hofmann, W.J.1    Moller, P.2    Otto, H.F.3
  • 130
    • 0025861327 scopus 로고
    • Interleukin-1, interleukin-6: Messengers in the neuroendocrine immune system?
    • Hooghe-Peters E, Velkeniers B, Vanhaelst L, Hooghe R. 1991. Interleukin-1, interleukin-6: messengers in the neuroendocrine immune system? Pathol Res Pract 187:622-625.
    • (1991) Pathol Res Pract , vol.187 , pp. 622-625
    • Hooghe-Peters, E.1    Velkeniers, B.2    Vanhaelst, L.3    Hooghe, R.4
  • 131
    • 0031752035 scopus 로고    scopus 로고
    • Introduction: Hormones, blood cells and immunity, with special reference to prolactin, growth hormone and insulin-like growth factor-I
    • Hooghe-Peters EL, Hooghe R. 1998. Introduction: hormones, blood cells and immunity, with special reference to prolactin, growth hormone and insulin-like growth factor-I. Cell Mol Life Sci 54:1057-1058.
    • (1998) Cell Mol Life Sci , vol.54 , pp. 1057-1058
    • Hooghe-Peters, E.L.1    Hooghe, R.2
  • 133
    • 0027505062 scopus 로고
    • Identification and characterization of hematopoietic stem cells from the yolk sac of the early mouse embryo
    • Huang H, Auerbach R. 1993. Identification and characterization of hematopoietic stem cells from the yolk sac of the early mouse embryo. Proc Natl Acad Sci USA 90:10110-10114.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10110-10114
    • Huang, H.1    Auerbach, R.2
  • 134
    • 0024413792 scopus 로고
    • Migration of putative progenitor T cells in response to thymus-derived chemotactic factors
    • Imaizumi A, Torisu M, Watanabe H, Yoshida T. 1989. Migration of putative progenitor T cells in response to thymus-derived chemotactic factors. Cell Immunol 120:301-313.
    • (1989) Cell Immunol , vol.120 , pp. 301-313
    • Imaizumi, A.1    Torisu, M.2    Watanabe, H.3    Yoshida, T.4
  • 135
    • 0027245433 scopus 로고
    • Interleukin-1 beta measured by radioimmunoassay in the rat spleen and thymus is increased during chronic inflammatory stress
    • Jessop DS, Chowdrey HS, Lightman SL. 1993. Interleukin-1 beta measured by radioimmunoassay in the rat spleen and thymus is increased during chronic inflammatory stress. Neuropeptides 24:367-371.
    • (1993) Neuropeptides , vol.24 , pp. 367-371
    • Jessop, D.S.1    Chowdrey, H.S.2    Lightman, S.L.3
  • 136
    • 0023119089 scopus 로고
    • Cell kinetics in the fetal mouse thymus: Precursor cell input, proliferation, and emigration
    • Jotereau F, Heuze F, Salomon-Vie, Gascan H. 1987. Cell kinetics in the fetal mouse thymus: precursor cell input, proliferation, and emigration. J Immunol 138:1026-1030.
    • (1987) J Immunol , vol.138 , pp. 1026-1030
    • Jotereau, F.1    Heuze, F.2    Salomon-Vie3    Gascan, H.4
  • 139
    • 0018963093 scopus 로고
    • The weight of the human thymus gland at necropsy
    • Kendall MD, Johnson HR, Singh J. 1980. The weight of the human thymus gland at necropsy. J Anat 131:483-497.
    • (1980) J Anat , vol.131 , pp. 483-497
    • Kendall, M.D.1    Johnson, H.R.2    Singh, J.3
  • 140
    • 0025835426 scopus 로고
    • Functional anatomy of the thymic microenvironment
    • Kendall MD. 1991. Functional anatomy of the thymic microenvironment. J Anat 177:1-29.
    • (1991) J Anat , vol.177 , pp. 1-29
    • Kendall, M.D.1
  • 143
    • 0030255879 scopus 로고    scopus 로고
    • Thymic involution: Why bother?
    • Kendall MD. 1996. Thymic involution: why bother? Immunol Today 17:492-493.
    • (1996) Immunol Today , vol.17 , pp. 492-493
    • Kendall, M.D.1
  • 144
    • 0033647071 scopus 로고    scopus 로고
    • The thymus in the mouse changes its activity during pregnancy: A study of the microenvironment
    • Kendall MD, Clarke AG. 2000. The thymus in the mouse changes its activity during pregnancy: a study of the microenvironment. J Anat 197 Pt 3:393-411.
    • (2000) J Anat , vol.197 , Issue.PART 3 , pp. 393-411
    • Kendall, M.D.1    Clarke, A.G.2
  • 147
    • 0028182883 scopus 로고
    • Sex hormones as negative regulators of lymphopoiesis
    • Kincade PW, Medina KL, Smithson G. 1994. Sex hormones as negative regulators of lymphopoiesis. Immunol Rev 137:119-134.
    • (1994) Immunol Rev , vol.137 , pp. 119-134
    • Kincade, P.W.1    Medina, K.L.2    Smithson, G.3
  • 148
    • 0028036488 scopus 로고
    • To be or not to be: Mutually antagonistic death signals regulate thymocyte apoptosis
    • King LB, Vacchio MS, Ashwell JD. 1994. To be or not to be: mutually antagonistic death signals regulate thymocyte apoptosis. Int Arch Allergy Immunol 105:355-358.
    • (1994) Int Arch Allergy Immunol , vol.105 , pp. 355-358
    • King, L.B.1    Vacchio, M.S.2    Ashwell, J.D.3
  • 149
    • 0017782437 scopus 로고
    • Evolution of ageing
    • Kirkwood TB. 1977. Evolution of ageing. Nature 270:301-304.
    • (1977) Nature , vol.270 , pp. 301-304
    • Kirkwood, T.B.1
  • 150
    • 0028872616 scopus 로고
    • Development and selection of T cells: Facts and puzzles
    • Kisielow P, von Boehmer H. 1995. Development and selection of T cells: facts and puzzles. Adv Immunol 58:87-209.
    • (1995) Adv Immunol , vol.58 , pp. 87-209
    • Kisielow, P.1    Von Boehmer, H.2
  • 152
    • 0029819158 scopus 로고    scopus 로고
    • Prolactin, growth hormone, and insulin-like growth factor-I in the immune system
    • Kooijman R, Hooghe-Peters EL, Hooghe R. 1996. Prolactin, growth hormone, and insulin-like growth factor-I in the immune system. Adv Immunol 63:377-454.
    • (1996) Adv Immunol , vol.63 , pp. 377-454
    • Kooijman, R.1    Hooghe-Peters, E.L.2    Hooghe, R.3
  • 156
    • 0031048376 scopus 로고    scopus 로고
    • Mouse hepatitis viral infection induces an extrathymic differentiation of the specific intrahepatic alpha beta-TCRintermediate LFA-1high T-cell population
    • Lamontagne L, Massicotte E, Page C. 1997. Mouse hepatitis viral infection induces an extrathymic differentiation of the specific intrahepatic alpha beta-TCRintermediate LFA-1high T-cell population. Immunology 90:402-411.
    • (1997) Immunology , vol.90 , pp. 402-411
    • Lamontagne, L.1    Massicotte, E.2    Page, C.3
  • 157
    • 0031783281 scopus 로고    scopus 로고
    • Intrahepatic alpha beta-TcRintermediate LFA-1high T cells are stimulated during mouse hepatitis viral infection
    • Lamontagne L, Massicotte E, Page C. 1998. Intrahepatic alpha beta-TcRintermediate LFA-1high T cells are stimulated during mouse hepatitis viral infection. Adv Exp Med Biol 440:479-483.
    • (1998) Adv Exp Med Biol , vol.440 , pp. 479-483
    • Lamontagne, L.1    Massicotte, E.2    Page, C.3
  • 159
    • 0028833045 scopus 로고
    • Extrathymic intestinal T-cell development: Virtual reality?
    • Lefrancois L, Puddington L. 1995. Extrathymic intestinal T-cell development: virtual reality? Immunol Today 16:16-21.
    • (1995) Immunol Today , vol.16 , pp. 16-21
    • Lefrancois, L.1    Puddington, L.2
  • 160
    • 0019877289 scopus 로고
    • An in vivo for thymus-homing bone marrow cells
    • Lepault F, Weissman IL. 1981. An in vivo for thymus-homing bone marrow cells. Nature 293:151-154.
    • (1981) Nature , vol.293 , pp. 151-154
    • Lepault, F.1    Weissman, I.L.2
  • 162
    • 0029826636 scopus 로고    scopus 로고
    • Antigen-independent changes in naive CD4 T cells with aging
    • Linton PJ, Haynes L, Klinman NR, Swain SL. 1996. Antigen-independent changes in naive CD4 T cells with aging. J Exp Med 184:1891-1900.
    • (1996) J Exp Med , vol.184 , pp. 1891-1900
    • Linton, P.J.1    Haynes, L.2    Klinman, N.R.3    Swain, S.L.4
  • 164
    • 0030801512 scopus 로고    scopus 로고
    • Pathways of T-cell regeneration in mice and humans: Implications for bone marrow transplantation and immunotherapy
    • Mackall CL, Gress RE. 1997a. Pathways of T-cell regeneration in mice and humans: implications for bone marrow transplantation and immunotherapy. Immunol Rev 157:61-72.
    • (1997) Immunol Rev , vol.157 , pp. 61-72
    • Mackall, C.L.1    Gress, R.E.2
  • 165
    • 0031466825 scopus 로고    scopus 로고
    • Thymic aging and T-cell regeneration
    • Mackall CL, Gress RE. 1997b. Thymic aging and T-cell regeneration. Immunol Rev 160:91-102.
    • (1997) Immunol Rev , vol.160 , pp. 91-102
    • Mackall, C.L.1    Gress, R.E.2
  • 166
    • 0031869628 scopus 로고    scopus 로고
    • Thymic function in young/old chimeras: Substantial thymic T cell regenerative capacity despite irreversible age-associated thymic involution
    • Mackall CL, Punt JA, Morgan P, Farr AG, Gress RE. 1998. Thymic function in young/old chimeras: substantial thymic T cell regenerative capacity despite irreversible age-associated thymic involution. Eur J Immunol 28:1886-1893.
    • (1998) Eur J Immunol , vol.28 , pp. 1886-1893
    • Mackall, C.L.1    Punt, J.A.2    Morgan, P.3    Farr, A.G.4    Gress, R.E.5
  • 168
    • 0024319314 scopus 로고
    • Luteinizing hormone-releasing hormone (LHRH) agonist restoration of age-associated decline of thymus weight, thymic LHRH receptors, and thymocyte proliferative capacity
    • Marchetti B, Guarcello V, Morale MC, Bartoloni G, Raiti F, Palumbo G, Jr., Farinella Z, Cordaro S, Scapagnini U. 1989. Luteinizing hormone-releasing hormone (LHRH) agonist restoration of age-associated decline of thymus weight, thymic LHRH receptors, and thymocyte proliferative capacity. Endocrinology 125:1037-1045.
    • (1989) Endocrinology , vol.125 , pp. 1037-1045
    • Marchetti, B.1    Guarcello, V.2    Morale, M.C.3    Bartoloni, G.4    Raiti, F.5    Palumbo Jr., G.6    Farinella, Z.7    Cordaro, S.8    Scapagnini, U.9
  • 169
    • 0027255330 scopus 로고
    • The neuro-endocrine component of the rat thymus: Studies on cultured thymic fragments before and after transplantation in congenitally athymic and euthymic rats
    • Martin-Fontecha A, Broekhuizen R, de Heer C, Zapata A, Schuurman HJ. 1993. The neuro-endocrine component of the rat thymus: studies on cultured thymic fragments before and after transplantation in congenitally athymic and euthymic rats. Brain Behav Immun 7:1-15.
    • (1993) Brain Behav Immun , vol.7 , pp. 1-15
    • Martin-Fontecha, A.1    Broekhuizen, R.2    De Heer, C.3    Zapata, A.4    Schuurman, H.J.5
  • 170
    • 0028812776 scopus 로고
    • How the glucocorticoids suppress immunity
    • Marx J. 1995. How the glucocorticoids suppress immunity. Science 270:232-233.
    • (1995) Science , vol.270 , pp. 232-233
    • Marx, J.1
  • 171
    • 0030889030 scopus 로고    scopus 로고
    • Pure red cell aplasia with thymona: Evidence of T-cell clonal disorder
    • Masuda M, Arai Y, Okamura T, Mizoguchi H. 1997. Pure red cell aplasia with thymona: evidence of T-cell clonal disorder. Am J Hematol 54:324-328.
    • (1997) Am J Hematol , vol.54 , pp. 324-328
    • Masuda, M.1    Arai, Y.2    Okamura, T.3    Mizoguchi, H.4
  • 173
    • 0028274828 scopus 로고
    • The influence of exercise and aging on immune function
    • Mazzeo RS. 1994. The influence of exercise and aging on immune function. Med Sci Sports Exerc 26:586-592.
    • (1994) Med Sci Sports Exerc , vol.26 , pp. 586-592
    • Mazzeo, R.S.1
  • 174
    • 0034074803 scopus 로고    scopus 로고
    • Aging, immune function, and exercise: Hormonal regulation
    • Mazzeo RS. 2000. Aging, immune function, and exercise: hormonal regulation. Int J Sports Med 21(Suppl 1):S10-13.
    • (2000) Int J Sports Med , vol.21 , Issue.SUPPL. 1
    • Mazzeo, R.S.1
  • 175
    • 0028670387 scopus 로고
    • Signalling and chromatin fragmentation in thymocyte apoptosis
    • McConkey DJ, Nicotera P, Orrenius S. 1994. Signalling and chromatin fragmentation in thymocyte apoptosis. Immunol Rev 142:343-363.
    • (1994) Immunol Rev , vol.142 , pp. 343-363
    • McConkey, D.J.1    Nicotera, P.2    Orrenius, S.3
  • 177
    • 0018889870 scopus 로고
    • BCG-induced changes in size of thymic cortex and thymus-dependent areas in spleen and lymph nodes of mice
    • Meyer EM, Grundmann E. 1980. BCG-induced changes in size of thymic cortex and thymus-dependent areas in spleen and lymph nodes of mice. Clin Exp Immunol 39:60-65.
    • (1980) Clin Exp Immunol , vol.39 , pp. 60-65
    • Meyer, E.M.1    Grundmann, E.2
  • 179
    • 0024428741 scopus 로고
    • Histochemistry of the acutely involved thymus in nickel chloride-treated rats
    • Milicevic NM, Milicevic Z. 1989. Histochemistry of the acutely involved thymus in nickel chloride-treated rats. J Comp Pathol 101:143-150.
    • (1989) J Comp Pathol , vol.101 , pp. 143-150
    • Milicevic, N.M.1    Milicevic, Z.2
  • 183
    • 0014744817 scopus 로고
    • Ontogeny of the haemopoietic system: Yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo
    • Moore MA, Metcalf D. 1970. Ontogeny of the haemopoietic system: yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo. Br J Haematol 18:279-296.
    • (1970) Br J Haematol , vol.18 , pp. 279-296
    • Moore, M.A.1    Metcalf, D.2
  • 184
    • 0026016705 scopus 로고
    • Blockade of central and peripheral luteinizing hormone-releasing hormone (LHRH) receptors in neonatal rats with a potent LHRH-antagonist inhibits the morphofunctional development of the thymus and maturation of the cell-mediated and humoral immune responses
    • Morale MC, Batticane N, Bartoloni G, Guarcello V, Farinella Z, Galasso MG, Marchetti B. 1991. Blockade of central and peripheral luteinizing hormone-releasing hormone (LHRH) receptors in neonatal rats with a potent LHRH-antagonist inhibits the morphofunctional development of the thymus and maturation of the cell-mediated and humoral immune responses. Endocrinology 128:1073-1085.
    • (1991) Endocrinology , vol.128 , pp. 1073-1085
    • Morale, M.C.1    Batticane, N.2    Bartoloni, G.3    Guarcello, V.4    Farinella, Z.5    Galasso, M.G.6    Marchetti, B.7
  • 185
    • 0023803246 scopus 로고
    • In vivo administration of IL-1 induces thymic hypoplasia and increased levels of serum corticosterone
    • Morrissey PJ, Charrier K, Alpert A, Bressler L. 1988. In vivo administration of IL-1 induces thymic hypoplasia and increased levels of serum corticosterone. J Immunol 141:1456-1463.
    • (1988) J Immunol , vol.141 , pp. 1456-1463
    • Morrissey, P.J.1    Charrier, K.2    Alpert, A.3    Bressler, L.4
  • 186
    • 0023939971 scopus 로고
    • Morphometrical analysis of the thymus from mice submitted to low temperature
    • Moura-Campos LC, Savino W. 1988. Morphometrical analysis of the thymus from mice submitted to low temperature. Acta Anat 132:9-11.
    • (1988) Acta Anat , vol.132 , pp. 9-11
    • Moura-Campos, L.C.1    Savino, W.2
  • 187
    • 0023676538 scopus 로고
    • Interleukin-6 stimulates the secretion of adrenocorticotropic hormone in conscious, freely-moving rats
    • Naitoh Y, Fukata J, Tominaga T, Nakai Y, Tamai S, Mori K, Imura H. 1988. Interleukin-6 stimulates the secretion of adrenocorticotropic hormone in conscious, freely-moving rats. Biochem Biophys Res Commun 155:1459-1463.
    • (1988) Biochem Biophys Res Commun , vol.155 , pp. 1459-1463
    • Naitoh, Y.1    Fukata, J.2    Tominaga, T.3    Nakai, Y.4    Tamai, S.5    Mori, K.6    Imura, H.7
  • 188
    • 0023350817 scopus 로고
    • Significance of increased secretion of glucocorticoids in mice and rats injected with bacterial endotoxin
    • Nakano K, Suzuki S, Oh C. 1987. Significance of increased secretion of glucocorticoids in mice and rats injected with bacterial endotoxin. Brain Behav Immun 1:159-172.
    • (1987) Brain Behav Immun , vol.1 , pp. 159-172
    • Nakano, K.1    Suzuki, S.2    Oh, C.3
  • 190
    • 0036484332 scopus 로고    scopus 로고
    • Induction of CD4+ regulatory T cells by TPA in mice: Contra-suppression by CD8+ T cells
    • Negoro T, Satoh K, Iinuma F, Tobe T, Watanabe M. 2002. Induction of CD4+ regulatory T cells by TPA in mice: contra-suppression by CD8+ T cells. Biol Pharm Bull 25:172-178.
    • (2002) Biol Pharm Bull , vol.25 , pp. 172-178
    • Negoro, T.1    Satoh, K.2    Iinuma, F.3    Tobe, T.4    Watanabe, M.5
  • 192
    • 0022547322 scopus 로고
    • Tumor-like massive thymic hyperplasia in childhood: A possible defect of
    • Nezelof C, Normand C. 1986. Tumor-like massive thymic hyperplasia in childhood: a possible defect of T-cell maturation, histological and cytoenzymatic studies of three cases. Thymus 8:177-186.
    • (1986) Thymus , vol.8 , pp. 177-186
    • Nezelof, C.1    Normand, C.2
  • 193
    • 0001922896 scopus 로고
    • The morphogenesis and histogenesis of the thymus gland in man
    • Norris EH. 1938. The morphogenesis and histogenesis of the thymus gland in man. Contrb Embriol 27:191-208.
    • (1938) Contrb Embriol , vol.27 , pp. 191-208
    • Norris, E.H.1
  • 195
    • 0025899105 scopus 로고
    • Thymic atrophy in type 2 reovirus infected mice: Immunosuppression and effects of thymic hormone. Thymic atrophy caused by reo-2
    • Onodera T, Taniguchi T, Tsuda T, Yoshihara K, Shimizu S, Sato M, Awaya A, Hayashi T. 1991. Thymic atrophy in type 2 reovirus infected mice: immunosuppression and effects of thymic hormone. Thymic atrophy caused by reo-2. Thymus 18:95-109.
    • (1991) Thymus , vol.18 , pp. 95-109
    • Onodera, T.1    Taniguchi, T.2    Tsuda, T.3    Yoshihara, K.4    Shimizu, S.5    Sato, M.6    Awaya, A.7    Hayashi, T.8
  • 196
    • 0036311982 scopus 로고    scopus 로고
    • Molecular characterization of the mouse involuted thymus: Aberrations in expression of transcription regulators in thymocyte and epithelial compartments
    • Ortman CL, Dittmar KA, Witte PL, Le PT. 2002. Molecular characterization of the mouse involuted thymus: aberrations in expression of transcription regulators in thymocyte and epithelial compartments. Int Immunol 14:813-822.
    • (2002) Int Immunol , vol.14 , pp. 813-822
    • Ortman, C.L.1    Dittmar, K.A.2    Witte, P.L.3    Le, P.T.4
  • 197
    • 0034860083 scopus 로고    scopus 로고
    • Nutrition disorders and immunologic parameters: Study of the thymus in growing rats
    • Pallaro AN, Roux ME, Slobodianik NH. 2001. Nutrition disorders and immunologic parameters: study of the thymus in growing rats. Nutrition 17:724-728.
    • (2001) Nutrition , vol.17 , pp. 724-728
    • Pallaro, A.N.1    Roux, M.E.2    Slobodianik, N.H.3
  • 200
    • 0036644685 scopus 로고    scopus 로고
    • Is human immunosenescence clinically relevant? Looking for "immunological risk phenotypes"
    • Pawelec G, Ouyang Q, Colonna-Romano G, Candore G, Lio D, Caruso C. 2002b. Is human immunosenescence clinically relevant? Looking for "immunological risk phenotypes". Trends Immunol 23:330-332.
    • (2002) Trends Immunol , vol.23 , pp. 330-332
    • Pawelec, G.1    Ouyang, Q.2    Colonna-Romano, G.3    Candore, G.4    Lio, D.5    Caruso, C.6
  • 202
    • 0017402558 scopus 로고
    • Thymus gland involution induced by lithium chloride
    • Perez-Cruet J, Dancey JT. 1977. Thymus gland involution induced by lithium chloride. Experientia 33:646-648.
    • (1977) Experientia , vol.33 , pp. 646-648
    • Perez-Cruet, J.1    Dancey, J.T.2
  • 204
    • 0035656088 scopus 로고    scopus 로고
    • TNF and Fas-induced apoptosis during negative selection in thymic nurse cells
    • Pezzano M, Samms M, Guyden JC. 2001. TNF and Fas-induced apoptosis during negative selection in thymic nurse cells. Ethn Dis 11:154-156.
    • (2001) Ethn Dis , vol.11 , pp. 154-156
    • Pezzano, M.1    Samms, M.2    Guyden, J.C.3
  • 205
    • 0035714449 scopus 로고    scopus 로고
    • Both age and gender affect thymic output: More recent thymic migrants in females than males as they age
    • Pido-Lopez J, Imami N, Aspinall R. 2001. Both age and gender affect thymic output: more recent thymic migrants in females than males as they age. Clin Exp Immunol 125:409-413.
    • (2001) Clin Exp Immunol , vol.125 , pp. 409-413
    • Pido-Lopez, J.1    Imami, N.2    Aspinall, R.3
  • 206
    • 0024730387 scopus 로고
    • Immunomodulators and feeding regulation: A humoral link between the immune and nervous systems
    • Plata-Salaman CR. 1989. Immunomodulators and feeding regulation: a humoral link between the immune and nervous systems. Brain Behav Immun 3:193-213.
    • (1989) Brain Behav Immun , vol.3 , pp. 193-213
    • Plata-Salaman, C.R.1
  • 207
    • 0021087223 scopus 로고
    • Seasonal cyclic changes in the thymus gland of the adult frog, Rana temporaria
    • Plytycz B, Bigaj J. 1983. Seasonal cyclic changes in the thymus gland of the adult frog, Rana temporaria. Thymus 5:327-344.
    • (1983) Thymus , vol.5 , pp. 327-344
    • Plytycz, B.1    Bigaj, J.2
  • 208
    • 0031942438 scopus 로고    scopus 로고
    • Age-related propensity to peripheral expansion of Vgamma3+ gammadelta+ T lymphocytes after irradiation and bone marrow transplantation
    • Poccia F, Cicconi R, Frasca D, Mancini C, Colizzi V, Doria G. 1998. Age-related propensity to peripheral expansion of Vgamma3+ gammadelta+ T lymphocytes after irradiation and bone marrow transplantation. Int Immunol 10:547-551.
    • (1998) Int Immunol , vol.10 , pp. 547-551
    • Poccia, F.1    Cicconi, R.2    Frasca, D.3    Mancini, C.4    Colizzi, V.5    Doria, G.6
  • 209
    • 0022376847 scopus 로고
    • Thymic microenvironmental factor: A possible chemoattractant for hemopoietic stem cells
    • Potworowski EF, Pyke KW. 1985. Thymic microenvironmental factor: a possible chemoattractant for hemopoietic stem cells. Thymus 7:345-356.
    • (1985) Thymus , vol.7 , pp. 345-356
    • Potworowski, E.F.1    Pyke, K.W.2
  • 210
    • 0033715726 scopus 로고    scopus 로고
    • Intrathymic T cell development and selection proceeds normally in the absence of glucocorticoid receptor signaling
    • Purton JF, Boyd RL, Cole TJ, Godfrey DI. 2000. Intrathymic T cell development and selection proceeds normally in the absence of glucocorticoid receptor signaling. Immunity 13:179-186.
    • (2000) Immunity , vol.13 , pp. 179-186
    • Purton, J.F.1    Boyd, R.L.2    Cole, T.J.3    Godfrey, D.I.4
  • 211
    • 0027372280 scopus 로고
    • A lymphostromal molecule, thymic shared Ag-1, regulates early thymocyte development in fetal thymus organ culture
    • Randle ES, Waanders GA, Masciantonio M, Godfrey DI, Boyd RL. 1993. A lymphostromal molecule, thymic shared Ag-1, regulates early thymocyte development in fetal thymus organ culture. J Immunol 151:6027-6035.
    • (1993) J Immunol , vol.151 , pp. 6027-6035
    • Randle, E.S.1    Waanders, G.A.2    Masciantonio, M.3    Godfrey, D.I.4    Boyd, R.L.5
  • 212
    • 0019350036 scopus 로고
    • Biologic properties of iscador: A Viscum album preparation I. Hyperplasia of the thymic cortex and accelerated regeneration of hematopoietic cells following X-irradiation
    • Rentea R, Lyon E, Hunter R. 1981. Biologic properties of iscador: a Viscum album preparation I. Hyperplasia of the thymic cortex and accelerated regeneration of hematopoietic cells following X-irradiation. Lab Invest 44:43-48.
    • (1981) Lab Invest , vol.44 , pp. 43-48
    • Rentea, R.1    Lyon, E.2    Hunter, R.3
  • 215
    • 43949162154 scopus 로고
    • Development in the thymus: It takes two to tango
    • Ritter MA, Boyd RL. 1993. Development in the thymus: it takes two to tango. Immunol Today 14:462-469.
    • (1993) Immunol Today , vol.14 , pp. 462-469
    • Ritter, M.A.1    Boyd, R.L.2
  • 216
    • 0024379007 scopus 로고
    • In the mouse, the activation of the hypothalamic-pituitary-adrenal axis by a lipopolysaccharide (endotoxin) is mediated through interleukin-1
    • Rivier C, Chizzonite R, Vale W. 1989. In the mouse, the activation of the hypothalamic-pituitary-adrenal axis by a lipopolysaccharide (endotoxin) is mediated through interleukin-1. Endocrinology 125:2800-2805.
    • (1989) Endocrinology , vol.125 , pp. 2800-2805
    • Rivier, C.1    Chizzonite, R.2    Vale, W.3
  • 217
    • 0024566412 scopus 로고
    • In the rat, interleukin-1 alpha acts at the level of the brain and the gonads to interfere with gonadotropin and sex steroid secretion
    • Rivier C, Vale W. 1989. In the rat, interleukin-1 alpha acts at the level of the brain and the gonads to interfere with gonadotropin and sex steroid secretion. Endocrinology 124:2105-2109.
    • (1989) Endocrinology , vol.124 , pp. 2105-2109
    • Rivier, C.1    Vale, W.2
  • 218
    • 0035989630 scopus 로고    scopus 로고
    • The disparity between human cell senescence in vitro and lifelong replication in vivo
    • Rubin H. 2002. The disparity between human cell senescence in vitro and lifelong replication in vivo. Nat Biotechnol, 20:675-681.
    • (2002) Nat Biotechnol , vol.20 , pp. 675-681
    • Rubin, H.1
  • 222
    • 0022690309 scopus 로고
    • Maturation of the adrenocortical stress response: Neuroendocrine control mechanisms and the stress hyporesponsive period
    • Sapolsky RM, Meaney MJ. 1986. Maturation of the adrenocortical stress response: neuroendocrine control mechanisms and the stress hyporesponsive period. Brain Res 396:64-76.
    • (1986) Brain Res , vol.396 , pp. 64-76
    • Sapolsky, R.M.1    Meaney, M.J.2
  • 223
    • 0026537924 scopus 로고
    • Chronic activation of the hypothalamo-pituitary-adrenal axis and loss of circadian rhythm during adjuvant-induced arthritis in the rat
    • Sarlis NJ, Chowdrey HS, Stephanou A, Lightman SL. 1992. Chronic activation of the hypothalamo-pituitary-adrenal axis and loss of circadian rhythm during adjuvant-induced arthritis in the rat. Endocrinology 130:1775-1779.
    • (1992) Endocrinology , vol.130 , pp. 1775-1779
    • Sarlis, N.J.1    Chowdrey, H.S.2    Stephanou, A.3    Lightman, S.L.4
  • 225
    • 0022913595 scopus 로고
    • Homing of hemopoietic precursor cells to the embryonic thymus: Characterization of an invasive mechanism induced by chemotactic peptides
    • Savagner P, Imhof BA, Yamada KM, Thiery JP. 1986. Homing of hemopoietic precursor cells to the embryonic thymus: characterization of an invasive mechanism induced by chemotactic peptides. J Cell Biol 103:2715-2727.
    • (1986) J Cell Biol , vol.103 , pp. 2715-2727
    • Savagner, P.1    Imhof, B.A.2    Yamada, K.M.3    Thiery, J.P.4
  • 227
    • 0029056760 scopus 로고
    • Pregnancy-associated effect on mouse thymocytes in vitro
    • Savion S, Toder V. 1995. Pregnancy-associated effect on mouse thymocytes in vitro. Cell Immunol 162:282-287.
    • (1995) Cell Immunol , vol.162 , pp. 282-287
    • Savion, S.1    Toder, V.2
  • 228
    • 0028879819 scopus 로고
    • Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
    • Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS, Jr. 1995a. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270:283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin Jr., A.S.4
  • 229
    • 0028831128 scopus 로고
    • Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors
    • Scheinman RI, Gualberto A, Jewell CM, Cidlowski JA, Baldwin AS, Jr. 1995b. Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors. Mol Cell Biol 15:943-953.
    • (1995) Mol Cell Biol , vol.15 , pp. 943-953
    • Scheinman, R.I.1    Gualberto, A.2    Jewell, C.M.3    Cidlowski, J.A.4    Baldwin Jr., A.S.5
  • 231
    • 0027374863 scopus 로고
    • Alterations in interleukin-6 production by LPS- and Con A-stimulated mixed splenocytes, spleen macrophages and lymphocytes in prenatally diazepam-exposed rats
    • Schreiber AA, Frei K, Lichtensteiger W, Schlumpf M. 1993. Alterations in interleukin-6 production by LPS- and Con A-stimulated mixed splenocytes, spleen macrophages and lymphocytes in prenatally diazepam-exposed rats. Agents Actions 39:166-173.
    • (1993) Agents Actions , vol.39 , pp. 166-173
    • Schreiber, A.A.1    Frei, K.2    Lichtensteiger, W.3    Schlumpf, M.4
  • 232
    • 0026211576 scopus 로고
    • Age-associated involution: Significance of a physiologic process
    • Schuurman HJ, Nagelkerken L, De Weger RA, Rozing J. 1991. Age-associated involution: significance of a physiologic process. Thymus 18:1-6.
    • (1991) Thymus , vol.18 , pp. 1-6
    • Schuurman, H.J.1    Nagelkerken, L.2    De Weger, R.A.3    Rozing, J.4
  • 233
    • 0027321539 scopus 로고
    • Thoughts on the thymus and the T-lymphocyte repertoire. Relevance to the tolerance of the immune response
    • Schuurman HJ, Hu HZ, de Weger RA, Clevers HC. 1993. Thoughts on the thymus and the T-lymphocyte repertoire. Relevance to the tolerance of the immune response. Neth J Med 43:38-54.
    • (1993) Neth J Med , vol.43 , pp. 38-54
    • Schuurman, H.J.1    Hu, H.Z.2    De Weger, R.A.3    Clevers, H.C.4
  • 234
    • 0022556206 scopus 로고
    • Dynamics of early T cells: Prothymocyte migration and proliferation in the adult mouse thymus
    • Scollay R, Smith J, Stauffer V. 1986. Dynamics of early T cells: prothymocyte migration and proliferation in the adult mouse thymus. Immunol Rev 91:129-157.
    • (1986) Immunol Rev , vol.91 , pp. 129-157
    • Scollay, R.1    Smith, J.2    Stauffer, V.3
  • 235
    • 0018833714 scopus 로고
    • Thymus cell migration. Quantitative aspects of cellular traffic from the thymus to the periphery in mice
    • Scollay RG, Butcher EC, Weissman IL. 1980. Thymus cell migration. Quantitative aspects of cellular traffic from the thymus to the periphery in mice. Eur J Immunol 10:210-218.
    • (1980) Eur J Immunol , vol.10 , pp. 210-218
    • Scollay, R.G.1    Butcher, E.C.2    Weissman, I.L.3
  • 236
    • 34249007019 scopus 로고
    • A syndrome produced by diverse nocuous agents
    • Selye H. 1936a. A syndrome produced by diverse nocuous agents. Nature 138:32.
    • (1936) Nature , vol.138 , pp. 32
    • Selye, H.1
  • 237
    • 0000668139 scopus 로고
    • Thymus and adrenals in the response of the organism to injuries and intoxication
    • Selye H. 1936b. Thymus and adrenals in the response of the organism to injuries and intoxication. Br J Exp Pathol 17:234.
    • (1936) Br J Exp Pathol , vol.17 , pp. 234
    • Selye, H.1
  • 238
  • 240
    • 0028080192 scopus 로고
    • Immunology. Death in the thymus
    • Shortman K, Scollay R. 1994. Immunology. Death in the thymus. Nature 372:44-45.
    • (1994) Nature , vol.372 , pp. 44-45
    • Shortman, K.1    Scollay, R.2
  • 241
    • 0029261617 scopus 로고
    • Morphologic characteristics of the thymus in pregnant and newborn mice exposed to sodium arsenite
    • Skal'naia MG, Zhavoronkov AA, Skal'nyi AV, Riabchikov OP. 1995. Morphologic characteristics of the thymus in pregnant and newborn mice exposed to sodium arsenite. Arkh Patol 57:52-58.
    • (1995) Arkh Patol , vol.57 , pp. 52-58
    • Skal'naia, M.G.1    Zhavoronkov, A.A.2    Skal'nyi, A.V.3    Riabchikov, O.P.4
  • 242
    • 0021261415 scopus 로고
    • Immunologic effects of nickel: I. Suppression of cellular and humoral immunity
    • Smialowicz RJ, Rogers RR, Riddle MM, Stott GA. 1984. Immunologic effects of nickel: I. Suppression of cellular and humoral immunity. Environ Res 33:413-427.
    • (1984) Environ Res , vol.33 , pp. 413-427
    • Smialowicz, R.J.1    Rogers, R.R.2    Riddle, M.M.3    Stott, G.A.4
  • 243
    • 0033769778 scopus 로고    scopus 로고
    • Evaluation of thymopoiesis using T cell receptor excision circles (TRECs): Differential correlation between adult and pediatric TRECs and naive phenotypes
    • Steffens CM, Al-Harthi L, Shott S, Yogev R, Landay A. 2000. Evaluation of thymopoiesis using T cell receptor excision circles (TRECs): differential correlation between adult and pediatric TRECs and naive phenotypes. Clin Immunol 97:95-101.
    • (2000) Clin Immunol , vol.97 , pp. 95-101
    • Steffens, C.M.1    Al-Harthi, L.2    Shott, S.3    Yogev, R.4    Landay, A.5
  • 244
    • 0022377731 scopus 로고
    • The involution of the ageing human thymic epithelium is independent of puberty. A morphometric study
    • Steinmann GG, Klaus B, Muller-Hermelink HK. 1985. The involution of the ageing human thymic epithelium is independent of puberty. A morphometric study. Scand J Immunol 22:563-575.
    • (1985) Scand J Immunol , vol.22 , pp. 563-575
    • Steinmann, G.G.1    Klaus, B.2    Muller-Hermelink, H.K.3
  • 246
    • 0028054017 scopus 로고
    • T-cell apoptosis detected in situ during positive and negative selection in the thymus
    • Surh CD, Sprent J. 1994. T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 372:100-103.
    • (1994) Nature , vol.372 , pp. 100-103
    • Surh, C.D.1    Sprent, J.2
  • 247
    • 0023114643 scopus 로고
    • Cortical thymocyte differentiation in thymomas: An immunohistologic analysis of the pathologic microenvironment
    • Takacs L, Savino W, Monostori E, Ando I, Bach JF, Dardenne M. 1987. Cortical thymocyte differentiation in thymomas: an immunohistologic analysis of the pathologic microenvironment. J Immunol 138:687-698.
    • (1987) J Immunol , vol.138 , pp. 687-698
    • Takacs, L.1    Savino, W.2    Monostori, E.3    Ando, I.4    Bach, J.F.5    Dardenne, M.6
  • 249
    • 0023126599 scopus 로고
    • In vitro bone marrow cell migration to supernatants prepared from thymic epithelial cell cultures
    • Taubenberger JK, Haar JL. 1987a. In vitro bone marrow cell migration to supernatants prepared from thymic epithelial cell cultures. Thymus 9:45-60.
    • (1987) Thymus , vol.9 , pp. 45-60
    • Taubenberger, J.K.1    Haar, J.L.2
  • 250
    • 0023093159 scopus 로고
    • The initial characterization of a thymus factor chemotactic to bone marrow cells
    • Taubenberger JK, Haar JL. 1987b. The initial characterization of a thymus factor chemotactic to bone marrow cells. Thymus 9:85-93.
    • (1987) Thymus , vol.9 , pp. 85-93
    • Taubenberger, J.K.1    Haar, J.L.2
  • 251
    • 0024434009 scopus 로고
    • Histopathological studies on experimental marine toxin poisoning: 4. Pathogenesis of experimental maitotoxin poisoning
    • Terao K, Ito E, Kakinuma Y, Igarashi K, Kobayashi M, Ohizumi Y, Yasumoto T. 1989. Histopathological studies on experimental marine toxin poisoning: 4. Pathogenesis of experimental maitotoxin poisoning. Toxicon 27:979-988.
    • (1989) Toxicon , vol.27 , pp. 979-988
    • Terao, K.1    Ito, E.2    Kakinuma, Y.3    Igarashi, K.4    Kobayashi, M.5    Ohizumi, Y.6    Yasumoto, T.7
  • 252
    • 0034813281 scopus 로고    scopus 로고
    • Rejuvenation of degenerative thymus by oral melatonin administration and the antagonistic action of melatonin against hydroxyl radical-induced apoptosis of cultured thymocytes in mice
    • Tian YM, Li PP, Jiang XF, Zhang GY, Dai YR. 2001. Rejuvenation of degenerative thymus by oral melatonin administration and the antagonistic action of melatonin against hydroxyl radical-induced apoptosis of cultured thymocytes in mice. J Pineal Res 31:214-221.
    • (2001) J Pineal Res , vol.31 , pp. 214-221
    • Tian, Y.M.1    Li, P.P.2    Jiang, X.F.3    Zhang, G.Y.4    Dai, Y.R.5
  • 253
    • 0032738430 scopus 로고    scopus 로고
    • Progesterone receptors in the thymus are required for thymic involution during pregnancy and for normal fertility
    • Tibbetts TA, DeMayo F, Rich S, Conneely OM, O'Malley BW. 1999. Progesterone receptors in the thymus are required for thymic involution during pregnancy and for normal fertility. Proc Natl Acad Sci USA 96:12021-12026.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12021-12026
    • Tibbetts, T.A.1    DeMayo, F.2    Rich, S.3    Conneely, O.M.4    O'Malley, B.W.5
  • 254
    • 0030740211 scopus 로고    scopus 로고
    • The immune-neuro-endocrine interactions
    • Tomaszewska D, Przekop F. 1997. The immune-neuro-endocrine interactions. J Physiol Pharmacol 48:139-158.
    • (1997) J Physiol Pharmacol , vol.48 , pp. 139-158
    • Tomaszewska, D.1    Przekop, F.2
  • 255
    • 0023892743 scopus 로고
    • Ageing and autoantibodies
    • Tomer Y, Shoenfeld Y. 1988. Ageing and autoantibodies. Autoimmunity 1:141-149.
    • (1988) Autoimmunity , vol.1 , pp. 141-149
    • Tomer, Y.1    Shoenfeld, Y.2
  • 258
    • 0024537460 scopus 로고
    • Hypertrophy of the thymus and restoration of immune functions in mice and rats by gonadectomy
    • Utsuyama M, Hirokawa K. 1989. Hypertrophy of the thymus and restoration of immune functions in mice and rats by gonadectomy. Mech Ageing Dev 47:175-185.
    • (1989) Mech Ageing Dev , vol.47 , pp. 175-185
    • Utsuyama, M.1    Hirokawa, K.2
  • 259
    • 0030812047 scopus 로고    scopus 로고
    • Induction of thymic hyperplasia and suppression of splenic T cells by lesioning of the anterior hypothalamus in aging Wistar rats
    • Utsuyama M, Kobayashi S, Hirokawa K. 1997. Induction of thymic hyperplasia and suppression of splenic T cells by lesioning of the anterior hypothalamus in aging Wistar rats. J Neuroimmunol 77:174-180.
    • (1997) J Neuroimmunol , vol.77 , pp. 174-180
    • Utsuyama, M.1    Kobayashi, S.2    Hirokawa, K.3
  • 260
    • 0028233225 scopus 로고
    • Steroid production in the thymus: Implications for thymocyte selection
    • Vacchio MS, Papadopoulos V, Ashwell JD. 1994. Steroid production in the thymus: implications for thymocyte selection. J Exp Med 179:1835-1846.
    • (1994) J Exp Med , vol.179 , pp. 1835-1846
    • Vacchio, M.S.1    Papadopoulos, V.2    Ashwell, J.D.3
  • 261
    • 0031011063 scopus 로고    scopus 로고
    • Thymus-derived glucocorticoids regulate antigen-specific positive selection
    • Vacchio MS, Ashwell JD. 1997. Thymus-derived glucocorticoids regulate antigen-specific positive selection. J Exp Med 185:2033-2038.
    • (1997) J Exp Med , vol.185 , pp. 2033-2038
    • Vacchio, M.S.1    Ashwell, J.D.2
  • 262
    • 0025909785 scopus 로고
    • Reversibility of thymic atrophy induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and bis(tri-n-butyltin)oxide (TBTO)
    • Van Loveren H, Schuurman HJ, Kampinga J, Vos JG. 1991. Reversibility of thymic atrophy induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and bis(tri-n-butyltin)oxide (TBTO). Int J Immunopharmacol 13:369-377.
    • (1991) Int J Immunopharmacol , vol.13 , pp. 369-377
    • Van Loveren, H.1    Schuurman, H.J.2    Kampinga, J.3    Vos, J.G.4
  • 264
    • 0031172368 scopus 로고    scopus 로고
    • Aspects of lymphocyte developmental biology
    • von Boehmer H. 1997. Aspects of lymphocyte developmental biology. Immunol Today 18:260-262.
    • (1997) Immunol Today , vol.18 , pp. 260-262
    • Von Boehmer, H.1
  • 265
    • 0024502409 scopus 로고
    • The thymus selects the useful, neglects the useless and destroys the harmful
    • von Boehmer H, Teh HS, Kisielow P. 1989. The thymus selects the useful, neglects the useless and destroys the harmful. Immunol Today 10:57-61.
    • (1989) Immunol Today , vol.10 , pp. 57-61
    • Von Boehmer, H.1    Teh, H.S.2    Kisielow, P.3
  • 266
    • 10544242196 scopus 로고    scopus 로고
    • Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2
    • Wagner DH Jr., Hagman J, Linsley PS, Hodsdon W, Freed JH, Newell MK 1996. Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2. J Exp Med 184:1631-1638.
    • (1996) J Exp Med , vol.184 , pp. 1631-1638
    • Wagner Jr., D.H.1    Hagman, J.2    Linsley, P.S.3    Hodsdon, W.4    Freed, J.H.5    Newell, M.K.6
  • 267
    • 0022456367 scopus 로고
    • Ontogeny of the stress response in the rat: Role of the pituitary and the hypothalamus
    • Walker CD, Perrin M, Vale W, Rivier C. 1986. Ontogeny of the stress response in the rat: role of the pituitary and the hypothalamus. Endocrinology 118:1445-1451.
    • (1986) Endocrinology , vol.118 , pp. 1445-1451
    • Walker, C.D.1    Perrin, M.2    Vale, W.3    Rivier, C.4
  • 268
    • 0027998179 scopus 로고
    • Thymus-neuroendocrine interactions in extrathymic T cell development
    • Wang J, Klein JR. 1994. Thymus-neuroendocrine interactions in extrathymic T cell development. Science 265:1860-1862.
    • (1994) Science , vol.265 , pp. 1860-1862
    • Wang, J.1    Klein, J.R.2
  • 270
    • 0027183729 scopus 로고
    • Glucocorticoid feedback regulation of adrenocortical responses to neural stimuli: Role of CRF-41 and corticosteroid type I and type II receptors
    • Weidenfeld J, Feldman S. 1993. Glucocorticoid feedback regulation of adrenocortical responses to neural stimuli: role of CRF-41 and corticosteroid type I and type II receptors. Neuroendocrinology 58:49-56.
    • (1993) Neuroendocrinology , vol.58 , pp. 49-56
    • Weidenfeld, J.1    Feldman, S.2
  • 271
    • 0024685855 scopus 로고
    • Expression of growth hormone by lymphocytes
    • Weigent DA, Blalock JE. 1989. Expression of growth hormone by lymphocytes. Int Rev Immunol 4:193-211.
    • (1989) Int Rev Immunol , vol.4 , pp. 193-211
    • Weigent, D.A.1    Blalock, J.E.2
  • 272
    • 0029101743 scopus 로고
    • Associations between the neuroendocrine and immune systems
    • Weigent DA, Blalock JE. 1995. Associations between the neuroendocrine and immune systems. J Leukoc Biol 58:137-150.
    • (1995) J Leukoc Biol , vol.58 , pp. 137-150
    • Weigent, D.A.1    Blalock, J.E.2
  • 273
    • 0002964496 scopus 로고
    • Development of the thyroid, parathyroid, and thymus glands in man
    • Weller GJ. 1933. Development of the thyroid, parathyroid, and thymus glands in man. Contrib Embryol 24:93-142.
    • (1933) Contrib Embryol , vol.24 , pp. 93-142
    • Weller, G.J.1
  • 274
    • 0028933798 scopus 로고
    • Neuroendocrine-immune system interactions and autoimmunity
    • Wilder RL. 1995. Neuroendocrine-immune system interactions and autoimmunity. Annu Rev Immunol 13:307-338.
    • (1995) Annu Rev Immunol , vol.13 , pp. 307-338
    • Wilder, R.L.1
  • 275
    • 0026474397 scopus 로고
    • Expression of interleukin (IL)-1 beta, IL-6 and their respective receptors in the normal rat brain and after injury
    • Yan HQ, Banos MA, Herregodts P, Hooghe R, Hooghe-Peters EL. 1992. Expression of interleukin (IL)-1 beta, IL-6 and their respective receptors in the normal rat brain and after injury. Eur J Immunol 22:2963-2971.
    • (1992) Eur J Immunol , vol.22 , pp. 2963-2971
    • Yan, H.Q.1    Banos, M.A.2    Herregodts, P.3    Hooghe, R.4    Hooghe-Peters, E.L.5
  • 276
    • 0026757091 scopus 로고
    • Characterization of interleukin-1 production by microglia in culture
    • Yao J, Keri JE, Taffs RE, Colton CA. 1992. Characterization of interleukin-1 production by microglia in culture. Brain Res 591:88-93.
    • (1992) Brain Res , vol.591 , pp. 88-93
    • Yao, J.1    Keri, J.E.2    Taffs, R.E.3    Colton, C.A.4
  • 278
    • 0029989925 scopus 로고    scopus 로고
    • Alternative pathways for the selection of antigen-specific peripheral T cells
    • Zheng B, Han S, Zhu Q, Goldsby R, Kelsoe G. 1996. Alternative pathways for the selection of antigen-specific peripheral T cells. Nature 384:263-266.
    • (1996) Nature , vol.384 , pp. 263-266
    • Zheng, B.1    Han, S.2    Zhu, Q.3    Goldsby, R.4    Kelsoe, G.5
  • 279
    • 0029061537 scopus 로고
    • Prevention of age-related T cell apoptosis defect in CD2-fas-transgenic mice
    • Zhou T, Edwards CK, 3rd, Mountz JD. 1995. Prevention of age-related T cell apoptosis defect in CD2-fas-transgenic mice. J Exp Med 182:129-137.
    • (1995) J Exp Med , vol.182 , pp. 129-137
    • Zhou, T.1    Edwards III, C.K.2    Mountz, J.D.3


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