Prion protein expression aids cellular uptake and veratridine-induced release of copper

Journal of Neuroscience Research

Volumn 58, Issue 5, 1999, Pages 717-725

  Brown, David R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Cerebellar; Function; PIPLC; Veratridine

Indexed keywords

COPPER; COPPER 67; HISTIDINE; PHOSPHOLIPASE C; PRION PROTEIN; VERATRIDINE;

ANIMAL CELL; ARTICLE; BRAIN CELL; CEREBELLUM; COPPER METABOLISM; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPSE; TRANSPORT KINETICS;

ANIMALS; CELLS, CULTURED; CEREBELLUM; COPPER; COPPER RADIOISOTOPES; CYTOSOL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; PRECIPITIN TESTS; PRPC PROTEINS; TIME FACTORS; VERATRIDINE;

EID: 0033485880     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19991201)58:5<717::AID-JNR13>3.0.CO;2-S     Document Type: Article

References (36)

1. 67 into veratridine releasable pool in brain tissue Am J Physiol 257: C315-C322.
2. Bolton DC, McKinley MP, Prusiner SB. 1982. Identification of a protein that purifies with the scrapie prion Science 218:1309-1311.
3. Brown DR, Besinger A. 1998. Prion protein expression and superoxide dismutase activity. Biochem J 334:423-429.
4. Brown DR, Schmidt B, Kretzschmar HA. 1996. Role of microglia and host prion protein in neurotoxicity of a prion protein fragment. Nature 380:345-347.
5. Brown DR, Qin K, Herms JW, Madlung A, Manson J, Strome R, Fraser PE, Kruck TA, von Bohlen A, Schulz-Schaeffer W, Giese A, Westaway D, Kretzschmar HA. 1997a. The cellular prion protein binds copper in vivo. Nature 390:684-687.
6. Brown DR, Schulz-Schaeffer WJ, Schmidt B, Kretzschmar HA. 1997b. Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp Neurol 146: 104-112.
7. Brown DR, Besinger A, Herms JW, Kretzschmar HA. 1998a. Microglial expression of the prion protein NeuroReport 9:1425-1429.
8. Brown DR, Schmidt B, Groschup MH, Kretzschmar HA. 1998b. Prion protein expression in muscle cells and toxicity of a prion protein fragment Eur J Cell Biol 75:29-37.
9. Büeler H, Fischer M, Lang Y, Bluethmann H, Lipp HP, DeArmond SJ, Prusiner SB, Aguet M, Weissmann C. 1992. Normal development and behaviour of mice lacking the neuronal cell surface PrP protein. Nature 356:577-582.
10. Colburn RW, Maas JW. 1965. Adenosine triphosphate-metal-norepinephrine ternary complexes and catecholamine binding Nature. 208:37-41.
11. Collinge J, Whittington MA, Sidle KCL, Smith CJ , Palmer MS, Clarke AR, Jefferys JGR. 1994. Prion protein is necessary for normal synaptic function Nature 370:295-297.
12. Fischer M, Rülicke T, Raeber A, Sailer A, Moser M, Oesch B, Brandner S, Aguzzi A, Weissmann C. 1996. Prion protein PrP, with amino-proximal deletions restoring suceptability of PrP knock-out mice to scrapie. EMBO J 15:1255-1264.
13. Fournier J-G, Escaig-Haye F, Billette de Villemeur T, and Robain O. 1995. Ultrastructural localization of cellular prion protein PrPc in synaptic boutons of normal hamster hippocampus. C R Acad Sci III 318: 339-344.
14. Gabrielsson B, Robson T, Norris D, Chung SH. 1986. Effects of divalent metal ions on the uptake of glutamate and GABA from synaptosomal fractions. Brian Res 384:218-223.
15. 67copper by two ligand-dependent saturable processes. A high affinity low capacity and a low affinity high capacity process. J Biol Chem 263:799-805.
16. Hirano T. 1991. Synaptic formations and modulations of synaptic transmissions between identified cerebellar neurons in culture. J Physiol 85:145-53.
17. Hope J, Reekie LJ, Hunter N, Multhaup G, Beyreuther K, White H, Scott AC, Stack M J, Dawson M, Wells GAH. 1988. Fibrils from brains of cows with new cattle disease contain scrapie-associated protein Nature 336:390-392.
18. Hornshaw MP, McDermott JR, Candy JM. 1995a. Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein Biochem Biophys Res Comm 207:621-629.
19. Hornshaw MP, McDermott JR, Candy JM, Lakey JH. 1995b. Copper binding to the N-terminal repeat region of mammalian and avian prion protein: structural studies using synthetic peptides. Biochem Biophys Res Comm 214:993-999.
20. Hsiao K, Prusiner SB. 1990. Inherited prion diseases. Neurology 40:1820-1827.
21. Kardos J, Kovás I, Hajós F, Kálmán M, Simonyi M. 1989. Nerve endings from rat brain tissue release copper upon depolarization: a possible role in regulating neuronal excitability. Neurosci Lett 103:139-144.
22. Kretzschmar HA, Prusiner SB, Stowring LE, DeArmond SJ. 1986. Scrapie prion proteins are synthesized in neurons Am J Pathol 122:1-5.
23. Marsh RF, Burger D, Eckroade R, Zu Rhein GM, Hanson RP. 1969. A preliminary report on the experimental host range of the transmissible mink encephalopathy agent. J Infect Dis 120: 713-719.
24. Marsh RF, Bessen RA, Lehmann S, Hartsough GR. 1991. Epidemiological and experimental studies on a new incident of transmissible mink encephalopathy. J Gen Virol 72:589-594.
25. Moser M, Colello RJ, Pott U, Oesch B. 1995. Developmental expression of the prion protein in glial cells Neuron 14:509-517.
26. Miura T, Hori-i A, Takeuchi H. 1996. Metal dependent a-helical formation promoted by glycine rich octapeptide region of prion protein. FEBS Lett 396:248-252
27. Pauly PC, Harris DA. 1998. Copper stimulates endocytosis of the prion protein J Biol Chem 273: 33107-33110.
28. Prusiner SB. 1982. Novel proteinaceous infectious particles cause scrapie. Science 216:136-144.
29. Prusiner SB. 1991. Molecular biology of prion disease. Science 252:1515-1522.
30. Prusiner SB, Hsiao K. 1994. Human prion disease Ann Neurol 35:385-395.
31. Salès N, Rodolfo K, Hässig R, Faucheux B, Di Giamberdino L, Moya KL. 1998. Cellular prion protein localization in rodent and primate brain Eur J Neurosci 10:2464-2471.
32. Schätzl HM, Da Costa M, Taylor M, Cohen FE, Prusiner SB. 1995. Prion protein gene variation among primates. J Mol Biol 245: 362-374.
33. Stahl N, Borchelt DR, Prusiner SB. 1990. Differential release of cellular and scrapie prion protein from cellular membranes of phosphatidylinositol specific phospholipase C. Biochemistry 29:5405-5412.
34. Stöckel JJ, Safar AC, Wallace FE, Cohen SB, Prusiner SB. 1998. Prion protein selectively binds copper II. ions Biochemistry. 37:7185-7193.
35. Tobler I, Gaus SE, Deboer T, Achermann P, Fischer M, Rülicke T, Moser M, Oesch B, McBride PA, Manson JC. 1996. Altered circadian rhythms and sleep in mice devoid of prion proteins Nature 380:639-642.
36. Vlachová V, Zemkova H, Vyklickt L Jr. 1996. Copper modulation of NMDA responses in mouse and rat cultured hippocampal neurons. Eur J Neurosci 8:2257-2264.