Enhancing the Modularity of the Modular Polyketide Synthases: Transacylation in Modular Polyketide Synthases Catalyzed by Malonyl-CoA:ACP Transacylase

Journal of the American Chemical Society

Volumn 125, Issue 47, 2003, Pages 14307-14312

  Kumar, Pawan ^a   Koppisch, Andrew T ^a   Cane, David E ^c   Khosla, Chaitan ^a,b  

^a Stanford University   (United States)

^b STANFORD UNIVERSITY   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLATION; BIOSYNTHESIS; CATALYST ACTIVITY; CHEMICAL MODIFICATION; ENZYME KINETICS; MOLECULAR STRUCTURE; PROTEINS; REACTION KINETICS;

FUNCTIONAL GROUPS;

BIOCHEMICAL ENGINEERING;

2 NOR 6 DEOXYERYTHRONOLIDE B; 6 DEOXYERYTHRONOLIDE B SYNTHASE; ACYL CARRIER PROTEIN TRANSACYLASE; ACYLTRANSFERASE; ERYTHRONOLIDE B; MALONYL COENZYME A; PANTETHEINE PHOSPHATE; POLYKETIDE SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CATALYST; ENZYME STRUCTURE; IN VITRO STUDY; IN VIVO STUDY; PROTEIN ANALYSIS; PROTEIN DOMAIN; STRUCTURE ANALYSIS;

ACYL CARRIER PROTEIN; ACYL-CARRIER PROTEIN S-MALONYLTRANSFERASE; ACYLTRANSFERASES; ERYTHROMYCIN; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MULTIENZYME COMPLEXES; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STREPTOMYCES;

EID: 0344875194     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja037429l     Document Type: Article

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