DNA-induced α-helix capping in conserved linker sequences is a determinant of binding affinity in Cys2-His2 zinc fingers

Journal of Molecular Biology

Volumn 295, Issue 4, 2000, Pages 719-727

  Laity, John H ^a   Dyson, H Jane ^a   Wright, Peter E ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Conserved TGEKP linker; DNA binding; NMR; TFIIIA; Wilms' tumor

Indexed keywords

ZINC FINGER PROTEIN;

ALPHA HELIX; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONSENSUS SEQUENCE; DNA BINDING; DNA HELIX; DNA PROTEIN COMPLEX; DNA SEQUENCE; DNA STRUCTURE; HYDROGEN BOND; NEPHROBLASTOMA; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

EID: 0034723158     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3406     Document Type: Article

References (35)

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14. 13C chemical shifts
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18. A finger protein structurally similar to TFIIIA that binds exclusively to 5S RNA in Xenopus
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22. Modeling unusual nucleic acid structures
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32. Relationship between nuclear magnetic resonance chemical shift and protein secondary structure
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35. Theory of the phase transition between helix and random coil