Activation Loop Ser744 and Ser748 in Protein Kinase D Are Transphosphorylated in Vivo

Journal of Biological Chemistry

Volumn 276, Issue 35, 2001, Pages 32606-32615

  Waldron, Richard T ^a   Rey, Osvaldo ^a   Iglesias, Teresa ^c   Tugal, Tamara ^b   Cantrell, Doreen ^b   Rozengurt, Enrique ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CELLS; CHEMICAL ACTIVATION; ENZYMES; FLUORESCENCE;

PHOSPHORYLATION;

BIOCHEMISTRY;

B LYMPHOCYTE RECEPTOR; BOMBESIN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PHORBOL ESTER; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN KINASE D; SERINE; UNCLASSIFIED DRUG; ANTIBODY; PEPTIDE FRAGMENT; PHOTOPROTEIN; RECOMBINANT PROTEIN;

ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; CELL TYPE; CONTROLLED STUDY; CROSS LINKING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; CELL LINE; CELL STRAIN 3T3; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; KINETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; PHOSPHORYLATION; RAT; SITE DIRECTED MUTAGENESIS;

ANIMALIA;

3T3 CELLS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME ACTIVATION; GREEN FLUORESCENT PROTEINS; HUMANS; KINETICS; LUMINESCENT PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN KINASE C; RATS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SERINE; TRANSFECTION;

EID: 0035980125     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101648200     Document Type: Article

References (50)

1. Berridge, M. J. (1993) Nature 361, 315-25
2. Nishizuka, Y. (1995) FASEB J. 9, 484-96
3. Nishizuka, Y. (1992) Science 258, 607-14
4. Dekker, L. V., and Parker, P. J. (1994) Trends Biochem. Sci. 19, 73-77
5. Mellor, H., and Parker, P. J. (1998) Biochem. J. 332, 281-292
6. Black, J. D. (2000) Front. Biosci. 5, D406-D423
7. Dempsey, E. C., Newton, A. C., Mochly-Rosen, D., Fields, A. P., Reyland, M. E., Insel, P. A., and Messing, R. O. (2000) Am. J. Physiol. 279, L429-L438
8. Nakanishi, H., Brewer, K. A., and Exton, J. H. (1993) J. Biol. Chem. 268, 13-16
9. Mochly-Rosen, D. (1995) Science 268, 247-251
10. Jaken, S., and Parker, P. J. (2000) Bioessays 22, 245-254
11. Valverde, A. M., Sinnett-Smith, J., Van Lint, J., and Rozengurt, E. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8572-8576
12. Johannes, F. J., Prestle, J., Eis, S., Oberhagemann, P., and Pfizenmaier, K. (1994) J. Biol. Chem. 269, 6140-6148
13. Prestle, J., Pfizenmaier, K., Brenner, J., and Johannes, F. J. (1996) J. Cell Biol. 134, 1401-1410
14. Jamora, C., Yamanouye, N., Van Lint, J., Laudenslager, J., Vandenheede, J. R., Faulkner, D. J., and Malhotra, V. (1999) Cell 98, 59-68
15. Liljedahl, M., Maeda, Y., Colanzi, A., Ayala, I., Van Lint, J., and Malhotra, V. (2001) Cell 104, 409-420
16. Bagowski, C. P., Stein-Gerlach, M., Choidas, A., and Ullrich, A. (1999) EMBO J. 18, 5567-5576
17. Hurd, C., and Rozengurt, E. (2001) Biochem. Biophys. Res. Commun. 282, 404-408
18. Haworth, R. S., Sinnett-Smith, J., Rozengurt, E., and Avkiran, M. (1999) Am. J. Physiol. 277, C1202-C1209
19. Häussermann, S., Kittstein, W., Rincke, G., Johannes, F. J., Marks, F., and Gschwendt, M. (1999) FEBS Lett. 462, 442-446
20. Endo, K., Oki, E., Biedermann, V., Kojima, H., Yoshida, K., Johannes, F. J., Kufe, D., and Datta, R. (2000) J. Biol. Chem. 275, 18476-18481
21. Bowden, E. T., Barth, M., Thomas, D., Glazer, R. I., and Mueller, S. C. (1999) Oncogene 18, 4440-4449
22. Van Lint, J., Sinnett-Smith, J., and Rozengurt, E. (1995) J. Biol. Chem. 270, 1455-1461
23. Waldron, R. T., Iglesias, T., and Rozengurt, E. (1999) J. Biol. Chem. 274, 9224-9230
24. Hayashi, A., Seki, N., Hattori, A., Kozuma, S., and Saito, T. (1999) Biochim. Biophys. Acta 1450, 99-106
25. Sturany, S., Van Lint, J., Mueller, F., Wilda, M., Hameister, H., Hoecker, M., Brey, A., Gem, U., Vandenheede, J., Gress, T., Adler, G., and Seufferlein, T. (2001) J. Biol. Chem. 276, 3310-3318
26. Rozengurt, E., Sinnett-Smith, J., Van Lint, J., and Valverde, A. M. (1995) Mutat. Res. 333, 153-160
27. Zugaza, J. L., Sinnett-Smith, J., Van Lint, J., and Rozengurt, E. (1996) EMBO J. 15, 6220-6230
28. Rozengurt, E., Sinnett-Smith, J., and Zugaza, J. L. (1997) Biochem. Soc. Trans. 25, 565-571
29. Zugaza, J. L., Waldron, R. T., Sinnett-Smith, J., and Rozengurt, E. (1997) J. Biol. Chem. 272, 23952-23960
30. Abedi, H., Rozengurt, E., and Zachary, I. (1998) FEBS Lett. 427, 209-212
31. Paolucci, L., and Rozengurt, E. (1999) Cancer Res. 59, 572-577
32. Paolucci, L., Sinnett-Smith, J., and Rozengurt, E. (2000) Am. J. Physiol. 278, C33-C39
33. Yuan, J., Slice, L., Walsh, J. H., and Rozengurt, E. (2000) J. Biol. Chem. 275, 2157-2164
34. Chiu, T. T., and Rozengurt, E. (2001) Am. J. Physiol. 280, C929-C942
35. Chiu, T. T., and Rozengurt, E. (2001) FEBS Lett. 489, 101-106
36. Matthews, S. A., Iglesias, T., Cantrell, D., and Rozengurt, E. (1999) FEBS Lett. 457, 515-521
37. Matthews, S. A., Iglesias, T., Rozengurt, E., and Cantrell, D. (2000) EMBO J. 19, 2935-2945
38. Matthews, S. A., Rozengurt, E., and Cantrell, D. (2000) J. Exp. Med. 191, 2075-2082
39. Waldron, R. T., and Rozengurt, E. (2000) J. Biol. Chem. 275, 17114-17121
40. Brooks, G., Goss, M. W., Rozengurt, E., and Galiñanes, M. (1997) J. Mol. Cell. Cardiol. 29, 2273-2283
41. Matthews, S. A., Pettit, G. R., and Rozengurt, E. (1997) J. Biol. Chem. 272, 20245-20250
42. Iglesias, T., Waldron, R. T., and Rozengurt, E. (1998) J. Biol. Chem. 273, 27662-27667
43. Waldron, R. T., Iglesias, T., and Rozengurt, E. (1999) Electrophoresis 20, 382-390
44. Vertommen, D., Rider, M., Ni, Y., Waelkens, E., Merlevede, W., Vandenheede, J. R., and Van Lint, J. (2000) J. Biol. Chem. 275, 19567-19576
45. Schönwasser, D. C., Marais, R. M., Marshall, C. J., and Parker, P. J. (1998) Mol. Cell. Biol. 18, 790-798
46. Le Good, J. A., Ziegler, W. H., Parekh, D. B., Alessi, D. R., Cohen, P., and Parker, P. J. (1998) Science 281, 2042-2045
47. Carter, R. H., Park, D. J., Rhee, S. G., and Fearon, D. T. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 2745-2749
48. Johnson, L. N., Lowe, E. D., Noble, M. E., and Owen, D. J. (1998) FEBS Lett. 430, 1-11
49. Johnson, L. N., Noble, M. E., and Owen, D. J. (1996) Cell 85, 149-158
50. Rey, O., Young, S. H., Cantrell, D., and Rozengurt, E. (2001) J. Biol. Chem. 276, 32616-32626