Second generation Taxanes: From the natural framework to the challenge of drug resistance

Current Medicinal Chemistry - Anti-Cancer Agents

Volumn 3, Issue 2, 2003, Pages 133-138

  Ferlini, Cristiano ^a   Ojima, Iwao ^c   Distefano, Mariagrazia ^a   Gallo, Daniela ^a   Riva, Antonella ^b   Morazzoni, Paolo ^b   Bombardelli, Ezio ^b   Mancuso, Salvatore ^a   Scambia, Giovanni ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b INDENA S P A   (Italy)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ALKENYL GROUP; ALKYL GROUP; ANTHRACYCLINE; ANTINEOPLASTIC AGENT; BACCATIN III; BETA TUBULIN; CISPLATIN; CORTICOSTEROID; CREMOPHOR; CYCLOPHOSPHAMIDE; DOCETAXEL; EPOTHILONE B; GLYCOPROTEIN P; ISOPROTEIN; ORTATAXEL; PACLITAXEL; POLYSORBATE 80; PROTEIN INHIBITOR; SB T 1031; SB T 1041; SB T 1051; SB T 1101; SB T 1102; SB T 1212; SB T 1213; SB T 1214; SB T 1302; TAXANE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ADVANCED CANCER; APOPTOSIS; BLOOD TOXICITY; BONE MARROW TOXICITY; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER RESISTANCE; CELL ACTIVATION; CELL CYCLE PHASE; CLINICAL TRIAL; DNA DAMAGE; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLASSIFICATION; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; DRUG HYPERSENSITIVITY; DRUG ISOLATION; DRUG MECHANISM; DRUG RESPONSE; DRUG SENSITIVITY; DRUG SYNTHESIS; DRUG TARGETING; FLUID RETENTION; HUMAN; LUNG NON SMALL CELL CANCER; MICROTUBULE; MITOSIS INHIBITION; NEUROTOXICITY; NONHUMAN; REVIEW; SKIN TOXICITY; STRUCTURE ACTIVITY RELATION; TAXUS BREVIFOLIA;

ANIMALS; ANTINEOPLASTIC AGENTS; BRIDGED COMPOUNDS; CLINICAL TRIALS; DRUG RESISTANCE, NEOPLASM; HUMANS; NEOPLASMS; TAXOIDS;

EID: 0344643459     PISSN: 15680118     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568011033353489     Document Type: Review

References (51)

1. Lee, M.R. Proc. R. Coll. Physicians Edinb., 1998, 28, 569.
2. Wani, M.C.; Taylor, H.L.; Wall, M.E.; Coggon, P.; McPhail, A.T. J. Am. Chem. Soc. 1971, 93, 2325.
3. Schiff, P.B.; Fant, J.; Horwitz, S.B. Nature, 1979, 277, 665.
4. Donehower, R.C.; Rowinsky, E.K.; Grochow, L.B.; Longnecker, S.M.; Ettinger, D.S. Cancer Treat Rep., 1987, 71, 1171.
5. Rowinsky, E.K.; Gilbert, M.R.; McGuire, W.P.; Noe, D.A.; Grochow, L.B.; Forastiere, A.A.; Ettinger, D.S.; Lubejko, B.G.; Clark, B.; Sartorius, S.E. J. Clin. Oncol., 1991, 9, 1692.
6. Anonymous Semin. Oncol. 1993, 20, 1.
7. Ringel, I.; Horwitz, S.B. J. Natl. Cancer Inst., 1991, 83, 288.
8. Bissery, M.C.; Guenard, D.; Gueritte-Voegelein, F.; Lavelle, F. Cancer Res., 1991, 51, 4845.
9. ten Bokkel, H.; Prove, A.M.; Piccart, M.; Steward, W.; Tursz, T.; Wanders, J.; Franklin, H.; Clavel, M.; Verweij, J.; Alakl, M. Ann. Oncol., 1994, 5, 527.
10. Cerny, T.; Kaplan, S.; Pavlidis, N.; Schoffski, P.; Epelbaum, R.; van Meerbeek, J.; Wanders, J.; Franklin, H.R.; Kaye, S. Br. J. Cancer, 1994, 70, 384.
11. McGuire, W.P.; Blessing, J.A.; Moore, D.; Lentz, S.S.; Photopulos, G. J. Clin. Oncol., 1996, 14, 792.
12. McGuire, W.P.; Hoskins, W.J.; Brady, M.F.; Kucera, P.R.; Partridge, E.E.; Look, K.Y.; Clarke-Pearson, D.L.; Davidson, M. N. Engl. J. Med., 1996, 334, 50.
13. Novello, S.; Le Chevalier, T. Semin. Oncol., 2001, 28, 3.
14. Calderoni, A.; Cerny, T. Crit. Rev. Oncol. Hematol., 2001, 38, 105.
15. Gianni, L.; Munzone, E.; Capri, G.; Fulfaro, F.; Tarenzi, E.; Villani, F.; Spreafico, C.; Laffranchi, A.; Caraceni, A.; Martini, C. J. Clin. Oncol., 1995, 13, 2688.
16. Nabholtz, J.M.; Mackey, J.R.; Smylie, M.; Paterson, A.; Noel, D.R.; Al-Tweigeri, T.; Tonkin, K.; North, S.; Azli, N.; Riva, A. J. Clin. Oncol., 2001, 19, 314.
17. Shin, D.M. Semin. Oncol., 2000, 27, 36.
18. McGuire, W.P.; Hoskins, W.J.; Brady, M.F.; Kucera, P.R.; Partridge, E.E.; Look, K.Y.; Clarke-Pearson, D.L.; Davidson, M. Semin. Oncol., 1996, 23, 40.
19. Piccart, M.J.; Bertelsen, K.; James, K.; Cassidy, J.; Mangioni, C.; Simonsen, E.; Stuart, G.; Kaye, S.; Vergote, I.; Blom, R.; Grimshaw, R.; Atkinson, R.J.; Swenerton, K.D.; Trope, C.; Nardi, M.; Kaern, J.; Tumolo, S.; Timmers, P.; Roy, J.A.; Lhoas, F.; Lindvall, B.; Bacon, M.; Birt, A.; Andersen, J.E.; Zee, B.; Paul, J.; Baron, B.; Pecorelli, S. J. Natl. Cancer Inst., 2000, 92, 699.
20. Hogberg, T.; Glimelius, B.; Nygren, P. Acta Oncol., 2001, 40, 340.
21. Vaishampayan, U.; Parchment, R.E.; Jasti, B.R.; Hussain, M. Urology, 1999, 54, 22.
22. Connelly, E.; Markman, M.; Kennedy, A.; Webster, K.; Kulp, B.; Peterson, G.; Belinson, J. Gynecol. Oncol., 1996, 62, 166.
23. Vasey, P.A.; Atkinson, R.; Coleman, R.; Crawford, M.; Cruickshank, M.; Eggleton, P.; Fleming, D.; Graham, J.; Parkin, D.; Paul, J.; Reed, N.S.; Kaye, S.B. Br. J. Cancer, 2001, 84, 170.
24. Markman, M.; Kennedy, A.; Webster, K.; Peterson, G.; Kulp, B.; Belinson, J. J. Clin. Oncol., 2001, 19, 1901.
25. Kavanagh, J.J.; Kudelka, A.P.; de Leon, C.G.; Tresukosol, D.; Hord, M.; Finnegan, M.B.; Kim, E.E.; Varma, D.; Forman, A.; Cohen, P.; Edwards, C.L.; Freedman, R.S.; Verschraegen, C.F. Clin. Cancer Res., 1996, 2, 837.
26. Verschraegen, C.F.; Sittisomwong, T.; Kudelka, A.P.; Guedes, E.; Steger, M.; Nelson-Taylor, T.; Vincent, M.; Rogers, R.; Atkinson, E.N.; Kavanagh, J.J. J. Clin. Oncol., 2000, 18, 2733.
27. Clarke, S.J.; Rivory, L.P.; Bernstein, B.J. Clin. Pharmacokinet, 1999, 36, 99.
28. Bernstein, B.J. Ann. Pharmacother., 2000, 34, 1332.
29. Moon, C.; Verschraegen, C.F.; Bevers, M.; Freedman, R.; Kudelka, A.P.; Kavanagh, J.J. Anticancer Drugs, 2000, 11, 565.
30. Volm, M. Anticancer Res., 1998, 18, 2905.
31. Chevillard, S.; Pouillart, P.; Beldjord, C.; Asselain, B.; Beuzeboc, P.; Magdelenat, H.; Vielh, P. Cancer, 1996, 77, 292.
32. Kerr, K.M.; Sauna, Z.E.; Ambudkar, S.V. J. Biol. Chem., 2001, 276, 8657.
33. Kaye, S.B. Curr. Opin. Oncol., 1998, 10 S1, S15-S19
34. Giannakakou, P.; Sackett, D.L.; Kang, Y.K.; Zhan, Z.; Buters, J.T.; Fojo, T.; Poruchynsky, M.S. J. Biol. Chem., 1997, 272, 17118.
35. Monzo, M.; Rosell, R.; Sanchez, J.J.; Lee, J.S.; O'Brate, A.; Gonzalez-Larriba, J.L.; Alberola, V.; Lorenzo, J.C.; Nunez, L.; Ro, J.Y.; Martin, C. J. Clin. Oncol., 1999, 17, 1786.
36. Tsurutani, J.; Komiya, T.; Uejima, H.; Tada, H.; Syunichi, N.; Oka, M.; Kohno, S.; Fukuoka, M.; Nakagawa, K. Lung Cancer, 2002, 35, 11.
37. Cleveland, D.W.; Sullivan, K.F. Annu. Rev. Biochem., 1985, 54, 331.
38. Lu, Q.; Luduena, R.F. Cell Struct. Funct., 1993, 18, 173.
39. Kavallaris, M.; Kuo, D.Y.S.; Burkhart, C.A.; Regl, D.L.; Norris, M.D.; Haber, M.; Horwitz, S.B. J. Clin. Invest., 1997, 100, 1282.
40. Burkhart, C.A.; Kavallaris, M.; Band, H.S. Biochim. Biophys. Acta, 1902, 1471, 01-09.
41. Nicoletti, M.I.; Valoti, G.; Giannakakou, P.; Zhan, Z.; Kim, J.H.; Lucchini, V.; Landoni, F.; Mayo, J.G.; Giavazzi, R.; Fojo, T. Clin. Cancer Res., 2001, 7, 2912,
42. Ojima, I.; Slater, J.C.; Michaud, E.; Kuduk, S.D.; Bounaud, P.Y.; Vrignaud, P.; Bissery, M.C.; Veith, J.M.; Pera, P.; Bernacki, R.J. J. Med. Chem., 1996, 39, 3889.
43. Ojima, I.; Kuduk, S.D.; Pera, P.; Veith, J.M.; Bernacki, R.J. J. Med. Chem., 1997, 40, 279.
44. Distefano, M.; Scambia, G.; Ferlini, C.; Gaggini, C.; De Vincenzo, R.; Riva, A.; Bombardelli, E.; Ojima, I.; Fattorossi, A.; Panici, P.B.; Mancuso, S. Int. J. Cancer, 1997, 72, 845.
45. Ferlini, C.; Distefano, M.; Pierelli, L.; Bonanno, G.; Riva, A.; Bombardelli, E.; Ojima, I.; Mancuso, S.; Scambia, G. Oncol. Res., 1999, 11, 471.
46. Ferlini, C.; Distefano, M.; Pignatelli, F.; Lin, S.; Riva, A.; Bombardelli, E.; Mancuso, S.; Ojima, I.; Scambia, G. Br. J. Cancer, 2000, 83, 1762.
47. Vredenburg, M.R.; Ojima, I.; Veith, J.; Pera, P.; Kee, K.; Cabral, F.; Sharma, A.; Kanter, P.; Greco, W.R.; Bernacki, R.J. J. Natl. Cancer Inst., 2001, 93, 1234.
48. Nicoletti, M.I.; Colombo, T.; Rossi, C.; Monardo, C.; Stura, S.; Zucchetti, M.; Riva, A.; Morazzoni, P.; Donati, M.B.; Bombardelli, E.; D'Incalci, M.; Giavazzi, R. Cancer Res., 2000, 60, 842.
49. Polizzi, D.; Pratesi, G.; Monestiroli, S.; Tortoreto, M.; Zunino, F.; Bombardelli, E.; Riva, A.; Morazzoni, P.; Colombo, T.; D'Incalci, M.; Zucchetti, M. Clin. Cancer Res., 2000, 6, 2070.
50. Sparreboom, A.; van Asperen, J.; Mayer, U.; Schinkel, A.H.; Smit, J.W.; Meijer, D.K.; Borst, P.; Nooijen, W.J.; Beijnen, J.H.; van Tellingen, O. Proc. Natl. Acad. Sci. USA, 1997, 94, 2031.
51. Laccabue, D.; Tortoreto, M.; Veneroni, S.; Perego, P.; Scanziani, E.; Zucchetti, M.; Zaffaroni, M.; D'Incalci, M.; Bombardelli, E.; Zunino, F.; Pratesi, G. Cancer, 2001, 92, 3085.