Paclitaxel has moderate activity in squamous cervix cancer: A Gynecologic Oncology Group study

Journal of Clinical Oncology

Volumn 14, Issue 3, 1996, Pages 792-795

  McGuire, W P ^a   Blessing, J A ^a   Moore, D ^a   Lentz, S S ^a   Photopulos, G ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PACLITAXEL;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; LEUKOPENIA; MAJOR CLINICAL STUDY; MICROTUBULE ASSEMBLY; NEUTROPENIA; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TREATMENT OUTCOME; UTERINE CERVIX CANCER;

EID: 0029865737     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1996.14.3.792     Document Type: Article

References (22)

1. Wani MC, Taylor HL, Wall MC, et al: Plant antitumor agents. VI. The isolation and structure of Taxol, a noval antileukemic and antitumor agent from Taxus brevifolia. J Am Chem Soc 93:2325-2327, 1971
2. Schiff PB, Fant J, Horwitz SB: Promotion of microtubule assembly in vitro by Taxol. Nature 22:665-667, 1979
3. National Cancer Institute Clinical Brochure: Taxol (NSC 125973). Bethesda, MD, Division of Cancer Treatment, National Cancer Institute, 1983, pp 6-12
4. Rowinsky EK, Cazenave LA, Donehower RC: Taxol: A novel investigational antineoplastic agent. J Natl Cancer Inst 82:1247-1259, 1990
5. Donehower RC, Rowinsky EK, Grochow LB, et al: Phase I trial of Taxol in patients with advanced cancer. Cancer Treat Rep 71:1171-1177, 1987
6. Wiernik PH, Schwartz EL, Strauman JJ, et al: Phase I clinical and pharmacokinetic study of Taxol. Cancer Res 47:2486-2493, 1987
7. Rowinsky EK, Burke PJ, Karp JE, et al: Phase I and pharmacodynamic study of Taxol in refractory actue leukemias. Cancer Res 49:4640-4647, 1989
8. Wiernik PH, Schwartz EL, Einzig A, et al: Phase I trial of Taxol given as a 24-hour infusion every 21 days: Responses observed in metastatic melanoma. J Clin Oncol 5:1232-1239, 1987
9. Grem JL, Tutsch KD, Simon KJ, et al: Phase I study of Taxol administered as a short iv infusion daily for 5 days. Cancer Treat Rep 71:1179-1184, 1987
10. Legha SS, Tenney DM, Krakoff IR: Phase I study of Taxol using a 5-day intermittent schedule. J Clin Oncol 4:762-766, 1986
11. Keia MG, O'Connell JP, Gralla RJ, et al: Phase I study of Taxol given as a 3-hour infusion every 21 days. Cancer Treat Rep 70:605-607, 1986
12. McGuire WP: Taxol: A new drug with significant activity as a salvage therapy in advanced epithelial ovarian cancer. Gynecol Oncol 51:78-85, 1993
13. McGuire WP, Rowinsky EK, Rosenshein NB, et al: Taxol: A unique antincoplastic agent with significant activity in advanced ovarian epithelial neoplasms. Ann Intern Med 111:273-279, 1989
14. Thigpen T, Blessing J, Ball H, et al: Phase II trial of Taxol as second-line therapy for ovarian cancinoma: A Gynecology Oncology Group study. Proc Am Soc Clin Oncol 9:156, 1990 (abstr 604)
15. Einzig AI, Wiernik PH, Sasloff J, et al: Phase II study and long-term follow-up of patients treated with Taxol for advanced ovarian cancer. J Clin Oncol 10:1748-1753, 1992
16. Omura GA: Chemotherapy for cervix cancer. Semin Oncol 21:54-62, 1994
17. Chang AY, Kim K, Glick J, et al: Phase II study of Taxol, merbarone, and piroxantrone in stage IV non-small-cell lung cancer: The Eastern Cooperative Oncology Group (ECOG) results. J Natl Cancer Inst 85:346-347, 1993
18. Murphy WK, Fosella FV, Winn RJ, et al: A phase II study of Taxol in patients with untreated, advanced non-small cell lung cancer. J Natl Cancer Inst 85:384-388, 1993
19. Forastiere AA: Use of Taxol in squamous carcinoma of the head and neck. Semin Oncol 20:56-60, 1993
20. Steren A, Seven BU, Perras J, et al: Taxol sensitized human ovarian cancer cells to radiation. Gynecol Oncol 48:252-258, 1993
21. Tishler RB, Gcard CR, Hall EJ, et al: Taxol sensitized human astrocytoma cells to radiation. Cancer Res 52:3495-3497, 1002
22. Rowinsky EK, Gilbert MR, McGuire WP, et al: Sequences of Taxol and cisplatin: A phase I and pharmacologic study. J Clin Oncol 9:1692-1703, 1991