-
1
-
-
0022876328
-
Huntington's disease: Pathogenesis and management
-
Martin JB, Gusella JF. Huntington's disease: pathogenesis and management. N Engl J Med 1986;315:1267-1276
-
(1986)
N Engl J Med
, vol.315
, pp. 1267-1276
-
-
Martin, J.B.1
Gusella, J.F.2
-
3
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993;72: 971-983
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
4
-
-
0027176364
-
The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease
-
Andrew SE, Goldberg YP, Kremer B, et al. The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease. Nat Genet 1993;4:398-403
-
(1993)
Nat Genet
, vol.4
, pp. 398-403
-
-
Andrew, S.E.1
Goldberg, Y.P.2
Kremer, B.3
-
5
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
Davies SW, Turmaine M, Cozenx BA, et al. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell 1997;90: 537-548
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozenx, B.A.3
-
6
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DiFiglia M, Sapp E, Chase KO, et al. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 1997;277:1990-1993
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.O.3
-
7
-
-
0032475941
-
Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice
-
Klement IA, Skinner PJ, Kaytor MD, et al. Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice. Cell 1998;95:41-53
-
(1998)
Cell
, vol.95
, pp. 41-53
-
-
Klement, I.A.1
Skinner, P.J.2
Kaytor, M.D.3
-
8
-
-
0032475931
-
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
-
Saudou F, Finkbeiner S, Devys D, Greenberg ME. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell 1998; 95:55-66
-
(1998)
Cell
, vol.95
, pp. 55-66
-
-
Saudou, F.1
Finkbeiner, S.2
Devys, D.3
Greenberg, M.E.4
-
9
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L, Sathasivam K, Seller M, et al. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 1996; 87:493-506
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
-
10
-
-
17344367977
-
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA
-
Reddy PH, Williams M, Charles V, et al. Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA. Nat Genet 1998;20: 198-202
-
(1998)
Nat Genet
, vol.20
, pp. 198-202
-
-
Reddy, P.H.1
Williams, M.2
Charles, V.3
-
11
-
-
0029082383
-
Inactivation of the mouse Huntington's disease gene homolog Hdh
-
Duyao MP, Auerbach AB, Ryan A, et al. Inactivation of the mouse Huntington's disease gene homolog Hdh. Science 1995; 269:407-410
-
(1995)
Science
, vol.269
, pp. 407-410
-
-
Duyao, M.P.1
Auerbach, A.B.2
Ryan, A.3
-
12
-
-
84993912315
-
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
-
Zeitlin S, Liu JP, Chapman DL, et al. Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue. Nat Genet 1995;11:155-163
-
(1995)
Nat Genet
, vol.11
, pp. 155-163
-
-
Zeitlin, S.1
Liu, J.P.2
Chapman, D.L.3
-
13
-
-
0030898510
-
A general purpose RNA-cleaving DNA enzyme
-
Santoro SW, Joyce GF. A general purpose RNA-cleaving DNA enzyme. Proc Natl Acad Sci USA 1997;94:4262-4266
-
(1997)
Proc Natl Acad Sci Usa
, vol.94
, pp. 4262-4266
-
-
Santoro, S.W.1
Joyce, G.F.2
-
14
-
-
0028019410
-
Gene inhibition using antisense oligodeoxynucleotides
-
Wagner RW. Gene inhibition using antisense oligodeoxynucleotides. Nature 1994;372:333-335
-
(1994)
Nature
, vol.372
, pp. 333-335
-
-
Wagner, R.W.1
-
15
-
-
0032558463
-
Mechanism and utility of an RNA-cleaving DNA enzyme
-
Santoro SW, Joyce GF. Mechanism and utility of an RNA-cleaving DNA enzyme. Biochemistry 1998;37:13330-13342
-
(1998)
Biochemistry
, vol.37
, pp. 13330-13342
-
-
Santoro, S.W.1
Joyce, G.F.2
-
16
-
-
0024477261
-
On finding all suboptimal folding of an RNA molecule
-
Zuker M. On finding all suboptimal folding of an RNA molecule. Science 1989;244:48-52
-
(1989)
Science
, vol.244
, pp. 48-52
-
-
Zuker, M.1
-
17
-
-
0029134549
-
Thermodynamic parameters to predict stability of RNA/DNA hybrid duplexes
-
Sugimoto N, Nakano S, Katoh M, et al. Thermodynamic parameters to predict stability of RNA/DNA hybrid duplexes. Biochemistry 1995;34:11211-11216
-
(1995)
Biochemistry
, vol.34
, pp. 11211-11216
-
-
Sugimoto, N.1
Nakano, S.2
Katoh, M.3
-
18
-
-
0024828055
-
A guide for probing native small nuclear RNA and ribonucleoprotein structures
-
Krol A, Carbot P. A guide for probing native small nuclear RNA and ribonucleoprotein structures. Methods Enzymol 1989;180:212-227
-
(1989)
Methods Enzymol
, vol.180
, pp. 212-227
-
-
Krol, A.1
Carbot, P.2
-
19
-
-
0029034511
-
Widespread expression of Huntington's disease gene (IT15) protein product
-
Sharp AH, Loev SJ, Schilling G, et al. Widespread expression of Huntington's disease gene (IT15) protein product. Neuron 1995;14:1065-1074
-
(1995)
Neuron
, vol.14
, pp. 1065-1074
-
-
Sharp, A.H.1
Loev, S.J.2
Schilling, G.3
-
20
-
-
0027330888
-
Using RNAFOLD to predict the activity of small catalytic RNAs
-
Denman RB. Using RNAFOLD to predict the activity of small catalytic RNAs. Biotechniques 1993;15:1090-1095
-
(1993)
Biotechniques
, vol.15
, pp. 1090-1095
-
-
Denman, R.B.1
-
21
-
-
0030948716
-
The genetic defect causing Huntington's disease: Repeated in other contexts?
-
Gusella JF, Persichetti F, MacDonald ME. The genetic defect causing Huntington's disease: repeated in other contexts? Mol Med 1997;3:238-246
-
(1997)
Mol Med
, vol.3
, pp. 238-246
-
-
Gusella, J.F.1
Persichetti, F.2
MacDonald, M.E.3
-
22
-
-
0031446233
-
Intranuclear neuronal inclusions: A common pathogenic mechanism for glutamine-repeat neurodegenerative diseases?
-
Ross CA. Intranuclear neuronal inclusions: a common pathogenic mechanism for glutamine-repeat neurodegenerative diseases? Neuron 1997;19:1147-1150
-
(1997)
Neuron
, vol.19
, pp. 1147-1150
-
-
Ross, C.A.1
-
23
-
-
0029055717
-
Targeted disruption ofthe Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
-
Nasir J, Floresco SB, O'Kusky JR, et al. Targeted disruption ofthe Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes. Cell 1995;81:811-823
-
(1995)
Cell
, vol.81
, pp. 811-823
-
-
Nasir, J.1
Floresco, S.B.2
O'Kusky, J.R.3
-
24
-
-
0030613177
-
Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion
-
White JK, Auerbach W, Duyao MP, et al. Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion. Nat Genet 1997;17:404-410
-
(1997)
Nat Genet
, vol.17
, pp. 404-410
-
-
White, J.K.1
Auerbach, W.2
Duyao, M.P.3
-
25
-
-
0028260436
-
Structure and expression of the Huntington's disease gene: Evidence against simple inactivation due to an expanded CAG repeat
-
Ambrose CM, Duyao MP, Barnes G, et al. Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat. Somat Cell Mol Genet 1994;20:27-38
-
(1994)
Somat Cell Mol Genet
, vol.20
, pp. 27-38
-
-
Ambrose, C.M.1
Duyao, M.P.2
Barnes, G.3
-
26
-
-
0029392854
-
HEAT repeats in the Huntington's disease protein
-
Andrade MA, Bork P. HEAT repeats in the Huntington's disease protein. Nat Genet 1995;11:115-116
-
(1995)
Nat Genet
, vol.11
, pp. 115-116
-
-
Andrade, M.A.1
Bork, P.2
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