-
1
-
-
0034932973
-
C-terminal fragment of amyloid precursor protein induces astrocytosis
-
Bach J.H., Chae H.S., Rah J.C., Lee M.W., Park C.H., Choi S.H., Choi J.K., Lee S.H., Kim Y.S., Kim K.Y., Lee W.B., Suh Y.H., Kim S.S. C-terminal fragment of amyloid precursor protein induces astrocytosis. J. Neurochem. 78:2001;109-120.
-
(2001)
J. Neurochem.
, vol.78
, pp. 109-120
-
-
Bach, J.H.1
Chae, H.S.2
Rah, J.C.3
Lee, M.W.4
Park, C.H.5
Choi, S.H.6
Choi, J.K.7
Lee, S.H.8
Kim, Y.S.9
Kim, K.Y.10
Lee, W.B.11
Suh, Y.H.12
Kim, S.S.13
-
2
-
-
0035203662
-
Key factors in Alzheimer's disease: Β-Amyloid precursor protein processing, metabolism and intraneuronal transport
-
Bayer T.A., Wirths O., Majtenyi K., Hartmann T., Multhaup G., Beyreuther K., Czech C. Key factors in Alzheimer's disease β-Amyloid precursor protein processing, metabolism and intraneuronal transport . Brain Pathol. 11:2001;1-11.
-
(2001)
Brain Pathol.
, vol.11
, pp. 1-11
-
-
Bayer, T.A.1
Wirths, O.2
Majtenyi, K.3
Hartmann, T.4
Multhaup, G.5
Beyreuther, K.6
Czech, C.7
-
3
-
-
0033586449
-
Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein
-
Berger-Sweeney J., McPhie D.L., Arters J.A., Greenan J., Oster-Granite M.L., Neve R.L. Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein. Mol. Brain Res. 66:1999;150-162.
-
(1999)
Mol. Brain Res.
, vol.66
, pp. 150-162
-
-
Berger-Sweeney, J.1
McPhie, D.L.2
Arters, J.A.3
Greenan, J.4
Oster-Granite, M.L.5
Neve, R.L.6
-
5
-
-
0036582717
-
Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice
-
Dewachter I., Reversé D., Caluwaerts N., Ris L., Kuipéri C., Van der Haute C., Spittaels K., Umans L., Serneels L., Thiry E., Moechars D., Mercken M., Godaux E., Van Leuven F. Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice. J. Neurosci. 22:2002;3445-3453.
-
(2002)
J. Neurosci.
, vol.22
, pp. 3445-3453
-
-
Dewachter, I.1
Reversé, D.2
Caluwaerts, N.3
Ris, L.4
Kuipéri, C.5
Van der Haute, C.6
Spittaels, K.7
Umans, L.8
Serneels, L.9
Thiry, E.10
Moechars, D.11
Mercken, M.12
Godaux, E.13
Van Leuven, F.14
-
6
-
-
16044366039
-
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1
-
Duff K., Eckman C., Zehr C., Yu X., Prada C.M., Perez-tur J., Hutton M., Buee L., Harigaya Y., Yager D., Morgan D., Gordon M.N., Holcomb L., Refolo L., Zenk B., Hardy J., Younkin S. Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1. Nature. 383:1996;710-713.
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.M.5
Perez-tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
7
-
-
0026725908
-
Membrane inserted APP fragments containing the beta A4 sequence of Alzheimer's disease do not aggregate
-
Dyrks T., Dyrks E., Masters C., Beyreuther K. Membrane inserted APP fragments containing the beta A4 sequence of Alzheimer's disease do not aggregate. FEBS Lett. 309:1992;20-24.
-
(1992)
FEBS Lett.
, vol.309
, pp. 20-24
-
-
Dyrks, T.1
Dyrks, E.2
Masters, C.3
Beyreuther, K.4
-
8
-
-
0029863648
-
Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie
-
Fischer M., Rulicke T., Raeber A., Sailer A., Moser M., Oesch B., Brandner S., Aguzzi A., Weissmann C. Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J. 15:1996;1255-1264.
-
(1996)
EMBO J.
, vol.15
, pp. 1255-1264
-
-
Fischer, M.1
Rulicke, T.2
Raeber, A.3
Sailer, A.4
Moser, M.5
Oesch, B.6
Brandner, S.7
Aguzzi, A.8
Weissmann, C.9
-
9
-
-
0027300915
-
Selective neurotoxicity of COOH-terminal fragments of the beta-amyloid precursor protein
-
Fukuchi K., Sopher B., Furlong C.E., Smith A.C., Dang N., Martin G.M. Selective neurotoxicity of COOH-terminal fragments of the beta-amyloid precursor protein. Neurosci. Lett. 154:1993;145-148.
-
(1993)
Neurosci. Lett.
, vol.154
, pp. 145-148
-
-
Fukuchi, K.1
Sopher, B.2
Furlong, C.E.3
Smith, A.C.4
Dang, N.5
Martin, G.M.6
-
10
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner G.G., Wong C.W. Alzheimer's disease initial report of the purification and characterization of a novel cerebrovascular amyloid protein . Biochem. Biophys. Res. Commun. 120:1984;885-890.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
11
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate A., Chartier-Harlin M.C., Mullan M., Brown J., Crawford F., Fidani L., Giuffra L., Haynes A., Irving N., James L., Mant R., Newton P., Rooke K., Roques P., Talbot C., Pericak-Vance M., Roses A., Wiliamson R., Rossor M., Owen M., Hardy J. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature. 349:1991;704-706.
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Wiliamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
12
-
-
0034966874
-
Presenilins as therapeutic targets for the treatment of Alzheimer's disease
-
Golde T.E., Younkin S.G. Presenilins as therapeutic targets for the treatment of Alzheimer's disease. Trends Mol. Med. 7:2001;264-269.
-
(2001)
Trends Mol. Med.
, vol.7
, pp. 264-269
-
-
Golde, T.E.1
Younkin, S.G.2
-
13
-
-
0033622324
-
Intraneuronal Abeta42 accumulation in human brain
-
Gouras G.K., Tsai J., Naslund J., Vincent B., Edgar M., Checler F., Greenfield J.P., Haroutunian V., Buxbaum J.D., Xu H., Greengard P., Relkin N.R. Intraneuronal Abeta42 accumulation in human brain. Am. J. Pathol. 156:2000;15-20.
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 15-20
-
-
Gouras, G.K.1
Tsai, J.2
Naslund, J.3
Vincent, B.4
Edgar, M.5
Checler, F.6
Greenfield, J.P.7
Haroutunian, V.8
Buxbaum, J.D.9
Xu, H.10
Greengard, P.11
Relkin, N.R.12
-
14
-
-
84985280160
-
The efficiency of systematic sampling in stereology and its prediction
-
Gundersen H.J.G., Jensen E.B. The efficiency of systematic sampling in stereology and its prediction. J. Microsc. 147:1987;229-263.
-
(1987)
J. Microsc.
, vol.147
, pp. 229-263
-
-
Gundersen, H.J.G.1
Jensen, E.B.2
-
15
-
-
0023760665
-
The new stereologicalal tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological re-search and diagnosis
-
Gundersen H.J.G., Bagger P., Bendtsen T.F., Evans S.M., Korbo L., Marcussen N., Møller A., Nielsen K., Nyengaard J.R., Pakkenberg B., Sørensen F.B., Vesterby A., West M.J. The new stereologicalal tools disector, fractionator, nucleator and point sampled intercepts and their use in pathological re-search and diagnosis . APMIS. 96:1988;857-881.
-
(1988)
APMIS
, vol.96
, pp. 857-881
-
-
Gundersen, H.J.G.1
Bagger, P.2
Bendtsen, T.F.3
Evans, S.M.4
Korbo, L.5
Marcussen, N.6
Møller, A.7
Nielsen, K.8
Nyengaard, J.R.9
Pakkenberg, B.10
Sørensen, F.B.11
Vesterby, A.12
West, M.J.13
-
16
-
-
0029661424
-
Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay
-
Ida N., Hartmann T., Pantel J., Schroder J., Zerfass R., Forstl H., Sandbrink R., Masters C.L., Beyreuther K. Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay. J. Biol. Chem. 271:1996;22908-22914.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22908-22914
-
-
Ida, N.1
Hartmann, T.2
Pantel, J.3
Schroder, J.4
Zerfass, R.5
Forstl, H.6
Sandbrink, R.7
Masters, C.L.8
Beyreuther, K.9
-
17
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang J., LeMaire H.G., Unterbeck A., Salbaum J.M., Masters C.L., Grzeschik K.H., Multhaup G., Beyreuther K., Mueller-Hill B. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature. 325:1987;733-736.
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
LeMaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
Multhaup, G.7
Beyreuther, K.8
Mueller-Hill, B.9
-
18
-
-
0037013327
-
Intracellular amyloid-beta 1-42, but not extracellular soluble amyloid-beta peptides, induces neuronal apoptosis
-
Kienlen-Campard P., Miolet S., Tasiaux B., Octave J.N. Intracellular amyloid-beta 1-42, but not extracellular soluble amyloid-beta peptides, induces neuronal apoptosis. J. Biol. Chem. 277:2002;15666-15670.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15666-15670
-
-
Kienlen-Campard, P.1
Miolet, S.2
Tasiaux, B.3
Octave, J.N.4
-
19
-
-
0035004122
-
Neuron loss during early adulthood following prenatal low-dose X-irradiation in the mouse brain
-
Korr H., Rohde H.T., Benders J., Dafotakis M., Grolms N., Schmitz C. Neuron loss during early adulthood following prenatal low-dose X-irradiation in the mouse brain. Int. J. Radiat. Biol. 77:2001;567-580.
-
(2001)
Int. J. Radiat. Biol.
, vol.77
, pp. 567-580
-
-
Korr, H.1
Rohde, H.T.2
Benders, J.3
Dafotakis, M.4
Grolms, N.5
Schmitz, C.6
-
20
-
-
0026608990
-
The neurotoxic corboxy-terminal fragment of the Alzheimer amyloid precursor binds to a neuronal cell surface molecule: PH dependence of the neurotoxicity and the binding
-
Kozlowski M.R., Spanoyannis A., Manly S.P., Fidel S.A., Neve R.L. The neurotoxic corboxy-terminal fragment of the Alzheimer amyloid precursor binds to a neuronal cell surface molecule pH dependence of the neurotoxicity and the binding . J. Neurosci. 12:1992;1679-1687.
-
(1992)
J. Neurosci.
, vol.12
, pp. 1679-1687
-
-
Kozlowski, M.R.1
Spanoyannis, A.2
Manly, S.P.3
Fidel, S.A.4
Neve, R.L.5
-
21
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad E., Wasco W., Poorkaj P., Romano D.M., Oshima J., Pettingell W.H., Yu C.E., Jondro P.D., Schmidt S.D., Wang K., Crowley A.C., Fu Y.H., Guenette S.Y., Galas D., Nemens E., Wijsman E.M., Bird T.D., Schellenberg G.D., Tanzi R.E. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science. 269:1995;973-977.
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.E.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
Crowley, A.C.11
Fu, Y.H.12
Guenette, S.Y.13
Galas, D.14
Nemens, E.15
Wijsman, E.M.16
Bird, T.D.17
Schellenberg, G.D.18
Tanzi, R.E.19
-
23
-
-
0032981558
-
Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein
-
Lichtenthaler S.F., Wang R., Grimm H., Uljon S.N., Masters C.L., Beyreuther K. Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein. Proc. Natl. Acad. Sci. USA. 96:1999;3053-3058.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3053-3058
-
-
Lichtenthaler, S.F.1
Wang, R.2
Grimm, H.3
Uljon, S.N.4
Masters, C.L.5
Beyreuther, K.6
-
24
-
-
0012510759
-
Amyloid plaque core protein in Alzheimer disease and Down syndrome
-
Masters C.L., Simms G., Weinman N.A., Multhaup G., McDonald B.L., Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl. Acad. Sci. USA. 82:1985;4245-4249.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 4245-4249
-
-
Masters, C.L.1
Simms, G.2
Weinman, N.A.3
Multhaup, G.4
McDonald, B.L.5
Beyreuther, K.6
-
25
-
-
0032874960
-
PC12 cells transfected with a C-terminal fragment of the amyloid precursor protein (APP C-100), exhibit enhanced sensitivity to the calcium ionophore A23187, and diminished sensitivity to hydrogen peroxide
-
McKeon-O'Malley C., Wells J., Fine R., Ullman M.D., Volicer L. PC12 cells transfected with a C-terminal fragment of the amyloid precursor protein (APP C-100), exhibit enhanced sensitivity to the calcium ionophore A23187, and diminished sensitivity to hydrogen peroxide. Mol. Brain Res. 72:1999;103-107.
-
(1999)
Mol. Brain Res.
, vol.72
, pp. 103-107
-
-
McKeon-O'Malley, C.1
Wells, J.2
Fine, R.3
Ullman, M.D.4
Volicer, L.5
-
26
-
-
0035900875
-
Beta-secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations
-
McPhie D.L., Golde T., Eckman C.B., Yager D., Brant J.B., Neve R.L. Beta-secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations. Mol. Brain Res. 97:2001;103-113.
-
(2001)
Mol. Brain Res.
, vol.97
, pp. 103-113
-
-
McPhie, D.L.1
Golde, T.2
Eckman, C.B.3
Yager, D.4
Brant, J.B.5
Neve, R.L.6
-
27
-
-
0026907151
-
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid
-
Mullan M., Crawford F., Axelman K., Houlden H., Lilius L., Winblad B., Lannfelt L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nature Genet. 1:1992;345-347.
-
(1992)
Nature Genet.
, vol.1
, pp. 345-347
-
-
Mullan, M.1
Crawford, F.2
Axelman, K.3
Houlden, H.4
Lilius, L.5
Winblad, B.6
Lannfelt, L.7
-
28
-
-
0029862137
-
Age-dependent neuronal and synaptic degeneration in mice transgenic for the C terminus of the amyloid precursor protein
-
Oster-Granite M.L., McPhie D.L., Greenan J., Neve R.L. Age-dependent neuronal and synaptic degeneration in mice transgenic for the C terminus of the amyloid precursor protein. J. Neurosci. 16:1996;6732-6741.
-
(1996)
J. Neurosci.
, vol.16
, pp. 6732-6741
-
-
Oster-Granite, M.L.1
McPhie, D.L.2
Greenan, J.3
Neve, R.L.4
-
29
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
Rogaev E.I., Sherrington R., Rogaeva E.A., Levesque G., Ikeda M., Liang Y., Chi H., Lin C., Holman K., Tsuda T., Sorbi S., Nacmias B., Piacentini S., Amaducci L., Chumakov I., Cohen D., Lannfelt L., Fraser P.E., Rommens J.M., St George-Hyslop P.H. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature. 376:1995;775-778.
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
Levesque, G.4
Ikeda, M.5
Liang, Y.6
Chi, H.7
Lin, C.8
Holman, K.9
Tsuda, T.10
Sorbi, S.11
Nacmias, B.12
Piacentini, S.13
Amaducci, L.14
Chumakov, I.15
Cohen, D.16
Lannfelt, L.17
Fraser, P.E.18
Rommens, J.M.19
St George-Hyslop, P.H.20
more..
-
30
-
-
0030754865
-
Neurodegeneration and gliosis in transgenic mice overexpressing a carboxy-terminal fragment of Alzheimer amyloid-beta protein precursor
-
Sato M., Kawarabayashi T., Shoji M., Kobayashi T., Tada N., Matsubara E., Hirai S. Neurodegeneration and gliosis in transgenic mice overexpressing a carboxy-terminal fragment of Alzheimer amyloid-beta protein precursor. Dement. Geriatr. Cogn. Disord. 8:1997;296-307.
-
(1997)
Dement. Geriatr. Cogn. Disord.
, vol.8
, pp. 296-307
-
-
Sato, M.1
Kawarabayashi, T.2
Shoji, M.3
Kobayashi, T.4
Tada, N.5
Matsubara, E.6
Hirai, S.7
-
31
-
-
16044373524
-
Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner D., Eckman C., Jensen M., Song X., Citron M., Suzuki N., Bird T.D., Hardy J., Hutton M., Kukull W., Larson E., Levy-Lahad E., Viitanen M., Peskind E., Poorkaj P., Schellenberg G., Tanzi R., Wasco W., Lannfelt L., Selkoe D., Younkin S. Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nature Med. 2:1996;864-870.
-
(1996)
Nature Med.
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
32
-
-
0031671811
-
Variation of fractionator estimates and its prediction
-
Schmitz C. Variation of fractionator estimates and its prediction. Anat. Embryol. 198:1998;371-397.
-
(1998)
Anat. Embryol.
, vol.198
, pp. 371-397
-
-
Schmitz, C.1
-
33
-
-
0033042975
-
Age-related changes of DNA repair and mitochondrial DNA synthesis in the mouse brain
-
Schmitz C., Axmacher B., Zunker U., Korr H. Age-related changes of DNA repair and mitochondrial DNA synthesis in the mouse brain. Acta Neuropathol. 97:1999;71-81.
-
(1999)
Acta Neuropathol.
, vol.97
, pp. 71-81
-
-
Schmitz, C.1
Axmacher, B.2
Zunker, U.3
Korr, H.4
-
34
-
-
0344603638
-
Neuron loss in the mouse hippocampus following prenatal injection of tritiated thymidine or saline
-
Schmitz C., Bultmann E., Gube M., Korr H. Neuron loss in the mouse hippocampus following prenatal injection of tritiated thymidine or saline. Int. J. Dev. Neurosci. 17:1999;185-190.
-
(1999)
Int. J. Dev. Neurosci.
, vol.17
, pp. 185-190
-
-
Schmitz, C.1
Bultmann, E.2
Gube, M.3
Korr, H.4
-
35
-
-
0033295451
-
Cell-type-specific differences in age-related changes of DNA repair in the mouse brain - Molecular basis for a new approach to understand the selective neuronal vulnerability in Alzheimer's disease
-
Schmitz C., Materne S., Korr H. Cell-type-specific differences in age-related changes of DNA repair in the mouse brain - Molecular basis for a new approach to understand the selective neuronal vulnerability in Alzheimer's disease. J. Alzheimer's Dis. 1:1999;387-407.
-
(1999)
J. Alzheimer's Dis.
, vol.1
, pp. 387-407
-
-
Schmitz, C.1
Materne, S.2
Korr, H.3
-
36
-
-
0033789892
-
Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach
-
Schmitz C., Hof P.R. Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach. J. Chem. Neuroanat. 20:2000;93-114.
-
(2000)
J. Chem. Neuroanat.
, vol.20
, pp. 93-114
-
-
Schmitz, C.1
Hof, P.R.2
-
37
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe D.J. Alzheimer's disease genes, proteins, and therapy . Physiol. Rev. 81:2001;741-766.
-
(2001)
Physiol. Rev.
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
38
-
-
0029004341
-
-
Sherrington R., Rogaev E.I., Liang Y., Rogaeva E.A., Levesque G., Ikeda M., Chi H., Lin C., Li G., Holman K., Tsuda T., Mar L., Foncin J.F., Bruni A.C., Montesi M.P., Sorbi S., Rainero I., Pinessi L., Nee L., Chumakov I., Pollen D., Brookes A., Sanseau P., Polinsky R.J., Wasco W., Dasilva Har, Haines J.L., Pericak-Vance M.A., Tanzi R.E. Nature. 375:1995;754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
Tsuda, T.11
Mar, L.12
Foncin, J.F.13
Bruni, A.C.14
Montesi, M.P.15
Sorbi, S.16
Rainero, I.17
Pinessi, L.18
Nee, L.19
Chumakov, I.20
Pollen, D.21
Brookes, A.22
Sanseau, P.23
Polinsky, R.J.24
Wasco, W.25
Dasilva Har26
Haines, J.L.27
Pericak-Vance, M.A.28
Tanzi, R.E.29
more..
-
39
-
-
0027971254
-
Cytotoxicity mediated by conditional expression of a carboxyl-terminal derivative of the beta-amyloid precursor protein
-
Sopher B.L., Fukuchi K., Smith A.C., Leppig K.A., Furlong C.E., Martin G.M. Cytotoxicity mediated by conditional expression of a carboxyl-terminal derivative of the beta-amyloid precursor protein. Mol. Brain Res. 26:1994;207-217.
-
(1994)
Mol. Brain Res.
, vol.26
, pp. 207-217
-
-
Sopher, B.L.1
Fukuchi, K.2
Smith, A.C.3
Leppig, K.A.4
Furlong, C.E.5
Martin, G.M.6
-
40
-
-
0030946552
-
An etiological role of amyloidogenic carboxyl-terminal fragments of the beta-amyloid precursor protein in Alzheimer's disease
-
Suh Y.H. An etiological role of amyloidogenic carboxyl-terminal fragments of the beta-amyloid precursor protein in Alzheimer's disease. J. Neurochem. 68:1997;1781-1791.
-
(1997)
J. Neurochem.
, vol.68
, pp. 1781-1791
-
-
Suh, Y.H.1
-
41
-
-
0033694131
-
Roles of A beta and carboxyl terminal peptide fragments of amyloid precursor protein in Alzheimer disease
-
Suh Y.H., Kim H.S., Lee J.P., Park C.H., Jeong S.J., Kim S.S., Rah J.C., Seo J.H., Kim S.S. Roles of A beta and carboxyl terminal peptide fragments of amyloid precursor protein in Alzheimer disease. J. Neural Transm. 58:(Suppl):2000;65-82.
-
(2000)
J. Neural Transm
, vol.58
, Issue.SUPPL.
, pp. 65-82
-
-
Suh, Y.H.1
Kim, H.S.2
Lee, J.P.3
Park, C.H.4
Jeong, S.J.5
Kim, S.S.6
Rah, J.C.7
Seo, J.H.8
Kim, S.S.9
-
42
-
-
10144263284
-
The beta-amyloid domain is essential for axonal sorting of amyloid precursor protein
-
Tienari P.J., De S.B., Ikonen E., Simons M., Weidemann A., Czech C., Hartmann T., Ida N., Multhaup G., Masters C.L., Van L.F., Beyreuther K., Dotti C.G. The beta-amyloid domain is essential for axonal sorting of amyloid precursor protein. EMBO J. 15:1996;5218-5229.
-
(1996)
EMBO J.
, vol.15
, pp. 5218-5229
-
-
Tienari, P.J.1
De, S.B.2
Ikonen, E.3
Simons, M.4
Weidemann, A.5
Czech, C.6
Hartmann, T.7
Ida, N.8
Multhaup, G.9
Masters, C.L.10
Van, L.F.11
Beyreuther, K.12
Dotti, C.G.13
-
43
-
-
0033793772
-
Perinatal asphyxia results in changes in presynaptic bouton number in striatum and cerebral cortex - A stereological and behavioral analysis
-
Van de Berg W.D.J., Blokland A., Cuello A.C., Schmitz C., Vreuls W., Steinbusch H.W.M., Blanco C.E. Perinatal asphyxia results in changes in presynaptic bouton number in striatum and cerebral cortex - A stereological and behavioral analysis. J. Chem. Neuroanat. 20:2000;71-82.
-
(2000)
J. Chem. Neuroanat.
, vol.20
, pp. 71-82
-
-
Van de Berg, W.D.J.1
Blokland, A.2
Cuello, A.C.3
Schmitz, C.4
Vreuls, W.5
Steinbusch, H.W.M.6
Blanco, C.E.7
-
44
-
-
0033623415
-
Abeta-generating enzymes: Recent advances in beta- and gamma-secretase research
-
Vassar R., Citron M. Abeta-generating enzymes recent advances in beta- and gamma-secretase research . Neuron. 27:2000;419-422.
-
(2000)
Neuron
, vol.27
, pp. 419-422
-
-
Vassar, R.1
Citron, M.2
-
45
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R., Bennett B.D., Babu-Khan S., Kahn S., Mendiaz E.A., Denis P., Teplow D.B., Ross S., Amarante P., Loeloff R., Luo Y., Fisher S., Fuller J., Edenson S., Lile J., Jarosinski M.A., Biere A.L., Curran E., Burgess T., Louis J.C., Collins F., Treanor J., Rogers G., Citron M. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science. 286:1999;735-741.
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
46
-
-
0024550204
-
Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein
-
Weidemann A., Konig G., Bunke D., Fischer P., Salbaum J.M., Masters C.L., Beyreuther K. Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell. 57:1989;115-126.
-
(1989)
Cell
, vol.57
, pp. 115-126
-
-
Weidemann, A.1
Konig, G.2
Bunke, D.3
Fischer, P.4
Salbaum, J.M.5
Masters, C.L.6
Beyreuther, K.7
-
47
-
-
0035933279
-
Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice
-
Wirths O., Multhaup G., Czech C., Blanchard V., Moussaoui S., Tremp G., Pradier L., Beyreuther K., Bayer T.A. Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice. Neurosci. Lett. 306:2001;116-120.
-
(2001)
Neurosci. Lett.
, vol.306
, pp. 116-120
-
-
Wirths, O.1
Multhaup, G.2
Czech, C.3
Blanchard, V.4
Moussaoui, S.5
Tremp, G.6
Pradier, L.7
Beyreuther, K.8
Bayer, T.A.9
-
48
-
-
0036019155
-
Intraneuronal APP/Aβ trafficking and plaque formation in β-amyloid precursor protein and presenilin-1 transgenic mice
-
Wirths O., Czech C., Feldmann F., Blanchard V., Tremp G., Multhaup G., Beyreuther K., Pradier L., Bayer T.A. Intraneuronal APP/Aβ trafficking and plaque formation in β-amyloid precursor protein and presenilin-1 transgenic mice. Brain Pathol. 12:2002;275-286.
-
(2002)
Brain Pathol
, vol.12
, pp. 275-286
-
-
Wirths, O.1
Czech, C.2
Feldmann, F.3
Blanchard, V.4
Tremp, G.5
Multhaup, G.6
Beyreuther, K.7
Pradier, L.8
Bayer, T.A.9
-
49
-
-
0031937121
-
Synaptic numbers across cortical laminae and cognitive performance of the rat during ageing
-
Wong T.P., Campbell P.M., Ribeiro-da-Silva A., Cuello A. Synaptic numbers across cortical laminae and cognitive performance of the rat during ageing. Neuroscience. 84:1998;403-412.
-
(1998)
Neuroscience
, vol.84
, pp. 403-412
-
-
Wong, T.P.1
Campbell, P.M.2
Ribeiro-da-Silva, A.3
Cuello, A.4
-
50
-
-
0024472693
-
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease
-
Yankner B.A., Dawes L.R., Fisher S., Villa-Komaroff L., Oster-Granite M.L., Neve R.L. Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease. Science. 245:1989;417-420.
-
(1989)
Science
, vol.245
, pp. 417-420
-
-
Yankner, B.A.1
Dawes, L.R.2
Fisher, S.3
Villa-Komaroff, L.4
Oster-Granite, M.L.5
Neve, R.L.6
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