The dissociation of cohesin from chromosomes in prophase is regulated by polo-like kinase

Molecular Cell

Volumn 9, Issue 3, 2002, Pages 515-525

  Sumara, Izabela ^a   Vorlaufer, Elisabeth ^a   Stukenberg, P Todd ^b   Kelm, Olaf ^c   Redemann, Norbert ^d   Nigg, Erich A ^c   Peters, Jan Michael ^a  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^b UNIVERSITY OF VIRGINIA   (United States)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^d BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COHESIN; PHOSPHOTRANSFERASE; POLO LIKE KINASE; UNCLASSIFIED DRUG;

ANAPHASE; ARTICLE; CHROMATIN; CHROMOSOME; CONTROLLED STUDY; ENZYME REGULATION; HELA CELL; HUMAN; HUMAN CELL; METAPHASE; MITOSIS; NONHUMAN; PROPHASE; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; XENOPUS;

VERTEBRATA;

EID: 0036209010     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(02)00473-2     Document Type: Article

References (33)

1. Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation
2. Phosphorylation of the cohesin subunit scc1 by polo/cdc5 kinase regulates sister chromatid separation in yeast
3. The rad21 gene product of Schizosacharomyces pombe is a nuclear, cell cycle regulated phosphoprotein
4. An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast
5. Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p
6. The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts
7. A MAP kinase-dependent actin checkpoint ensures proper spindle orientation in fission yeast
8. Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis
9. Polo-like kinases: A team that plays throughout mitosis
10. A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae
11. Cohesin cleavage by separase required for anaphase and cytokinesis in human cells
12. Chromosome cohesion, condensation, and separation
13. Human chromatid cohesin component hRad21 is phosphorylated in M phase and associated with metaphase centromeres
14. Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes
15. Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts
16. Identification of Xenopus SMC protein complexes required for sister chromatid cohesion
17. Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes
18. Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids
19. Splitting the chromosome: Cutting the ties that bind sister chromatids
20. Polo-like kinases: Positive regulators of cell division from start to finish
21. Pds5 cooperates with cohesin in maintaining sister chromatid cohesion
22. Subunits and substrates of the anaphase-promoting complex
23. Activated polo-like kinase Plx1 is required at multiple points during mitosis in Xenopus laevis
24. Mitotic effects of a constitutively active mutant of the Xenopus polo- like kinase Plx1
25. Characterization of vertebrate cohesin complexes and their regulation in prophase
26. Scanning electron microscopy of mammalian chromosomes from prophase to telophase
27. Characterization of fission yeast cohesin: Essential anaphase proteolysis of Rad21 phosphorylated in the S phase
28. Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication
29. Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1
30. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast
31. Spo76p is a conserved chromosome morphogenesis protein that links the mitotic and meiotic programs
32. Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase
33. Drad21, a Drosophila rad21 homologue expressed in S phase cells