A1 expression is stimulated by CD40 in B cells and rescues WEHI 231 cells from anti-IgM-induced cell death

European Journal of Immunology

Volumn 29, Issue 10, 1999, Pages 3077-3088

  Kuss, Andreas W ^a   Knödel, Matthias ^a   Berberich Siebelt, Friederike ^a   Lindemann, Dirk ^a   Schimpl, Anneliese ^a   Berberich, Ingolf ^a,b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Apoptosis; bcl 2; Growth arrest; Immature B cell; Maturation

Indexed keywords

CD40 ANTIGEN; IMMUNOGLOBULIN M ANTIBODY; VIRUS VECTOR;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CELL DEATH; CROSS LINKING; DOWN REGULATION; GENE CONTROL; GENETIC TRANSDUCTION; LYMPHOMA CELL LINE; MOUSE; NONHUMAN; ONCOGENE C MYC; PRIORITY JOURNAL; SURVIVAL RATE;

ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIGENS, CD40; APOPTOSIS; B-LYMPHOCYTES; CELL CYCLE; CELL DIVISION; CELL SURVIVAL; DNA FRAGMENTATION; DNA-BINDING PROTEINS; HOMEODOMAIN PROTEINS; IMMUNOGLOBULIN M; LYMPHOMA, B-CELL; MICE; PROTO-ONCOGENE PROTEINS C-BCL-2; REPLICATION PROTEIN C; REPRESSOR PROTEINS; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE PROTEINS; TUMOR CELLS, CULTURED;

EID: 0345426283     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199910)29:10<3077::AID-IMMU3077>3.0.CO;2-R     Document Type: Article

References (61)

1. Osmond, D. G. and Nossal, G. J. V., Differentiation of lymphocytes in mouse bone marrow. II. Kinetics of maturation and renewal of antiglobulin-binding cells studied by double labeling. Cell. Immunol. 1974. 13: 132-145.
2. MacLennan, I. C., B-cell receptor regulation of peripheral B cells. Curr. Opin. Immunol. 1998. 10: 220-225.
3. Healy, J. I. and Goodnow, C. C., Positive versus negative signaling by lymphocyte antigen receptors. Annu. Rev. Immunol. 1998. 16: 645-670.
4. Rolink, A. G., Andersson, J. and Melchers, F., Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity. Eur. J. Immunol. 1998. 28: 3738-3748.
5. Sater, R. A., Sandel, P. C. and Monroe, J. G., B cell receptor-induced apoptosis in primary transitional murine B cells: signaling requirements and modulation by T cell help. Int. Immunol. 1998. 10: 1673-1682.
6. van Kooten, C. and Banchereau, J., Functions of CD40 on B cells, dendritic cells and other cells. Curr. Opin. Immunol. 1997. 9: 330-337.
7. Smith, C. A., Farrah, T. and Goodwin, R. G., The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 1994. 76: 959-962.
8. Armitage, R. J., Fanslow, W. C., Strockbine, L., Sato, T. A., Clifford, K. N., Macduff, B. M., Anderson, D. M., Gimpel, S. D., Davis, S. T. and Maliszewski, C. R., Molecular and biological characterization of a murine ligand for CD40. Nature 1992. 357: 80-82.
9. Benhamou, L. E., Cazenave, P. A. and Sarthou, P., Anti-immunoglobulins induce death by apoptosis in WEHI-231 B lymphoma cells. Eur. J. Immunol. 1990. 20: 1405-1407.
10. Hasbold, J. and Klaus, G. G., Anti-immunoglobulin antibodies induce apoptosis in immature B cell lymphomas. Eur. J. Immunol 1990. 20: 1685-1690.
11. Tsubata, T., Wu, J. and Honjo, T., B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40. Nature 1993. 364: 645-648.
12. Gottschalk, A. R. and Quintans, J., Apoptosis in B lymphocytes: the WEHI-231 perspective, Immunol. Cell Biol. 1995. 73: 8-16.
13. Sonenshein, G. E., Rel NF-kappa B transcription factors and the control of apoptosis. Semin. Cancer Biol. 1997. 8: 113-119.
14. Lee, H., Arsura, M., Wu, M., Duyao, M., Buckler, A. J. and Sonenshein, G. E., Role of Rel-related factors in control of c-myc gene transcription in receptor-mediated apoptosis of the murine B cell WEHI 231 line. J. Exp. Med. 1995. 181: 1169-1177.
15. Arsura, M., Wu, M. and Sonenshein, G. E., TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha, Immunity 1996. 5: 31-40.
16. Wu, M., Lee, H., Bellas, R. E., Schauer, S. L., Arsura, M., Katz, D., FitzGerald, M. J., Rothstein, T. L., Sherr, D. H. and Sonenshein, G. E., Inhibition of MF-kappaB/Rel induces apoptosis of murine B cells. EMBO J. 1996. 15: 4682-4690.
17. Schauer, S. L., Wang, Z., Sonenshein, G. E. and Rothstein, T. L., Maintenance of nuclear factor-kappa B/Rel and c-myc expression during CD40 ligand rescue of WEHI 231 early B cells from receptor-mediated apoptosis through modulation of I kappe B proteins. J. Immunol. 1996. 157: 81-86.
18. Siebelt, F., Berberich, I., Shu, G., Serfling, E. and Clark, E. A., Role for CD40-mediated activation of c-Rel and maintenance of c-myc RNA levels in mitigating anti-IgM-induced growth arrest. Cell. Immunol. 1997. 181: 13-22.
19. Wu, M., Arsura, M., Bellas, R. E., FitzGerald, M. J., Lee, H., Schauer, S. L., Sherr, D. H. and Sonenshein, G. E., Inhibition of c-myc expression induces apoptosis of WEHI 231 murine B cells. Mol. Cell. Biol. 1996. 16: 5015-5025.
20. Chao, D. T. and Korsmeyer, S. J., BCL-2 family: regulators of cell death. Annu. Rev. Immunol. 1998. 16: 395-419.
21. Choi, M. S., Boise, L. H., Gottschalk, A. R., Quintans, J., Thompson, C. B. and Klaus, G. G., The role of bcl-XL in CD40-mediated rescue from anti-mu-induced apoptosis in WEHI-231 B lymphoma cells. Eur. J. Immunol. 1995. 25: 1352-1357.
22. Fang, W., Rivard, J. J., Ganser, J. A., LeBien, T. W., Nath, K. A., Mueller, D. L. and Behrens, T. W., Bcl-xL rescues WEHI 231 B lymphocytes from oxidant-mediated death following diverse apoptotic stimuli. J. Immunol. 1995. 155: 66-75.
23. Merino, R., Grillot, D. A., Simonian, P. L., Muthukkumar, S., Fanslow, W. C., Bondada, S. and Nunez, G., Modulation of anti-IgM-induced B cell apoptosis by Bcl-xL and CD40 in WEHI-231 cells. Dissociation from cell cycle arrest and dependence on the avidity of the antibody-IgM receptor interaction. J. Immunol. 1995. 155: 3830-3838.
24. Ishida, T., Kobayashi, N., Tojo, T., Ishida, S., Yamamoto, T. and Inoue, J., CD40 signaling-mediated induction of Bcl-XL, Cdk4, and Cdk6. Implication of their cooperation in selective B cell growth. J. Immunol. 1995. 155: 5527-5535.
25. Grillot, D. A., Merino, R., Pena, J. C., Fanslow, W. C., Finkelman, F. D., Thompson, C. B. and Nunez, G., bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice. J. Exp. Med. 1996. 183: 381-391.
26. Lin, E. Y., Orlofsky, A., Berger, M. S. and Prystowsky, M. B., Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2. J. Immunol. 1993. 151: 1979-1988.
27. Karsan, A., Yee, E. and Harlan, J. M., Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1. J. Biol. Chem. 1996. 271: 27201-27204.
28. D'Sa Eipper, C., Subramanian, T. and Chinnadurai, G., bfl-1, a bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity. Cancer Res. 1996. 56: 3879-3882.
29. Lin, E. Y., Orlofsky, A., Wang, H. G., Reed, J. C. and Prystowsky, M. B., A1, a Bcl-2 family member, prolongs cell survival and permits myeloid differentiation. Blood 1996. 87: 983-992.
30. Tomayko, M. M. and Cancro, M. P., Long-lived B cells are distinguished by elevated expression of A1. J. Immunol. 1998. 160: 107-111.
31. Wu, M., Yang, W., Bellas, R. E., Schauer, S. L., FitzGerald, M. J., Lee, H. and Sonenshein, G. E., c-myc promotes survival of WEHI 231 B lymphoma cells from apoptosis. Cure. Top. Microbiol. Immunol. 1997. 224: 91-101.
32. Austen, M., Cerni, C., Henriksson, M., Hilfenhaus, S., Luscher Firzlaff, J. M., Menkel, A., Seelos, C., Sommer, A. and Luscher, B., Regulation of cell growth by the Myc-Max-Mad network: role of Mad proteins and YY1. Curr. Top. Microbiol. Immunol. 1997. 224: 123-130.
33. Grumont, R. J., Rourke, I. J. and Gerondakis, S., Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis. Genes Dev. 1999. 13400-411.
34. Liu, Y. J., Joshua, D. E., Williams, G. T., Smith, C. A., Gordon, J. and MacLennan, I. C., Mechanism of antigen-driven selection in germinal centres. Nature 1989. 342: 929-931.
35. Turner, C. A., Jr., Mack, D. H. and Davis, M. M., Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. Cell 1994. 77: 297-306.
36. Messika, E. J., Lu, P. S., Sung, Y. J., Yao, T., Chi, J. T., Chien, Y. H. and Davis, M. M., Differential effect of B lymphocyte-induced maturation protein (Blimp-1) expression of cell fate during B cell development. J. Exp. Med. 1998. 188: 515-525.
37. Grumont, R. J. and Gerondakis, S., The subunit composition of NF-kappa B complexes changes during B-cell development. Cell Growth Differ. 1994. 5: 1321-1331.
38. Miyamoto, S., Schmitt, M. J. and Verma, I. M., Qualitative changes in the subunit composition of kappa B-binding complexes during murine B-cell differentiation. Proc. Natl. Acad. Sci. USA 1994. 91: 5056-5060.
39. Liou, H. C., Sha, W. C., Scott, M. L. and Baltimore, D., Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation. Mol. Cell. Biol. 1994. 14: 5349-5359.
40. Berberich, I., Shu, G. L. and Clark, E. A., Cross-linking CD40 on B cells rapidly activates nuclear factor-kappa B. J. Immunol. 1994. 153: 4357-4366.
41. Hanissian, S. H. and Geha, R. S., Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells. Immunity 1997. 6: 379-387.
42. Sakata, N., Patel, H. R., Terada, N., Aruffo, A., Johnson, G. L. and Gelfand, E. W., Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells. J. Biol. Chem. 1995. 270: 30823-30828.
43. Berberich, I., Shu, G., Siebelt, F., Woodgett, J. R., Kyriakis, J. M. and Clark, E. A., Cross-linking CD40 on B cells preferentially induces stress-activated protein kinases rather than mitogen-activated protein kinases. EMBO J. 1996. 15: 92-101.
44. Sutherland, C. L., Heath, A. W., Pelech, S. L., Young, P. R. and Gold, M. R., Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor. J. Immunol. 1996. 157: 3381-3390.
45. Grumont, R. J., Rourke, I. J., O'Reilly, L. A., Strasser, A., Miyake, K., Sha, W. and Gerondakis, S., B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells. J. Exp. Med. 1998. 187: 663-674.
46. Amati, B., Alevizopoulos, K. and Vlach, J., Myc and the cell cycle. Front. Biosci. 1998. 3: D250-268.
47. Han, H., Nomura, T., Honjo, T. and Tsubata, T., Differential modulation of cyclin-dependent kinase inhibitor p27Kip1 by negative signaling via the antigen receptor of B cells and positive signaling via CD40. Eur. J. Immunol. 1996. 26: 2425-2432.
48. Graves, J. D., Draves, K. E., Craxton, A., Krebs, E. G. and Clark, E. A., A comparison of signaling requirements for apoptosis of human B lymphocytes induced by the B cell receptor and CD95/Fas. J. Immunol. 1998. 161: 168-174.
49. Andjelic, S. and Liou, H. C., Antigen receptor-induced B lymphocyte apoptosis mediated via a protease of the caspase family. Eur. J. Immunol. 1998. 28: 570-581.
50. Chen, L., Kim, T. J. and Pillai, S., Inhibition of caspase activity prevents anti-IgM induced apoptosis but not ceramide generation of WEHI 231 B cells. Mol. Immunol. 1998. 35: 195-205.
51. Lens, S. M., den Drijver, B. F., Potgens, A. J., Tesselaar, K., van Oers, M. H. and van Lier, R. A., Dissection of pathways leading to antigen receptor-induced and Fas/CD95-induced apoptosis in human B cells. J. Immunol. 1998. 160: 6083-6092.
52. Thornberry, N. A. and Lazebnik, Y., Caspases: enemies within: Science 1998. 281: 1312-1316.
53. Zamzami, N., Susin, S. A., Marchetti, P., Hirsch, T., Gomez-Monterrey, I., Castedo, M. and Kroemer, G., Mitochondrial control of nuclear apoptosis. J. Exp. Med. 1996. 183: 1533-1544.
54. Gottschalk, A. R., Boise L. H., Thompson, C. B. and Quintans, J., Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2. Proc. Natl. Acad. Sci. USA 1994. 91: 7350-7354.
55. Green, D. R. and Reed, J. C., Mitochondria and apoptosis. Science 1998. 281: 1309-1312.
56. Hatakeyama, S., Hamasaki, A., Negishi, I., Loh, D. Y., Sendo, F. and Nakayama, K., Multiple gene duplication and expression of mouse bcl-2-related genes, A1. Int. Immunol. 1998. 10: 631-637.
57. DuBridge, R. B., Tang, P., Hsia, H. C., Leong, P. M., Miller, J. H. and Calos, M. P., Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system. Mol. Cell. Biol. 1987. 7: 379-387.
58. Chen Bettecken, U., Wecker, A. and Schimpl, A., IgM RNA switch from membrane to secretory form is prevented by adding antireceptor antibody to bacterial lipopolysaccharide-stimulated murine primary B-cell cultures. Proc. Natl. Acad. Sci. USA 1985. 82: 7384-7388.
59. Rolink, A., Melchers, F. and Andersson, J., The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching. Immunity 1996. 5: 319-330.
60. Lindemann, D., Patriquin, E., Feng, S. and Mulligan, R. C., Versatile retrovirus vector systems for regulated gene expression in vitro and in vivo. Mol. Med. 1997. 3: 466-476.
61. Soneoka, Y., Cannon, P. M., Ramsdale, E. E., Griffiths, J. C., Romano, G., Kingsman, S. M. and Kingsman, A. J., A transient three-plasmid expression system for the production of high titer retroviral vectors. Nucleic Acids Res. 1995. 23: 628-633.