Role of phosphatidylinositol 3-kinase in anti-IgM-and anti-IgD-induced apoptosis in B cell lymphomas

Journal of Immunology

Volumn 166, Issue 3, 2001, Pages 1618-1626

  Carey, G B ^a   Scott, D W ^a  

^a HOLLAND LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN D ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; IMMUNOGLOBULIN MU CHAIN; IMMUNOGLOBULIN RECEPTOR; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPID; PROTEIN P27; S6 KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; B CELL LYMPHOMA; CELL DEATH; CELL FATE; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; CROSS LINKING; DOWN REGULATION; GROWTH DISORDER; IMMUNOSTIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION;

EID: 0035253694     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.3.1618     Document Type: Article

References (60)

1. Apoptotic signal transduction: Emerging pathways
2. Immunoglobulins D and M mediate signals that are qualitatively different in B cells with an immature phenotype
3. Functional differences between immunoglobulins M and D expressed on the surface of an immature B-cell line
4. Anti-immunoglobulin antibodies induce apoptosis in immature B cell lymphomas
5. Role of c-myc and p27 in anti-IgM induced B-lymphoma apoptosis
6. Apoptosis in B lymphocytes: The WEHI-231 perspective
7. 1 growth arrest of murine B-cell lymphomas
8. Regulation of p27Kip1 accumulation in murine B-lymphoma cells: Role of c-Myc and calcium
9. Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation
10. Mysterious liaisons: The relationship between c-Myc and the cell cycle
11. Mechanisms of apoptosis by c-Myc
12. Isolation and characterization of c-myc, a cellular homolog of the oncogene (v-myc) of avian myelocytomatosis virus strain 29
13. Induction of apoptosis in fibroblasts by c-myc protein
14. The proto-oncogene c-myc and apoptosis
15. Signaling through the antigen receptor of B lymphocytes activates a p53-independent pathway of c-Myc-induced apoptosis
16. A Myc-induced apoptosis pathway surfaces
17. Activation-induced apoptosis in lymphocytes
18. Inhibition of c-myc expression induces apoptosis of WEHI 231 murine B cells
19. Stimulation of receptor-associated kinase, tyrosine kinase, and MAP kinase is required for prolactin-mediated macromolecular biosynthesis and mitogenesig in Nb2 lymphoma
20. Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k
21. A signaling pathway to translational control
22. Myc-mediated transformation: The repression connection
23. The Myc oncoprotein: A critical evaluation of transactivation and target gene regulation
24. Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F
25. Lymphoma models for B cell activation and tolerance. VIII. Cross-desensitization by slgM and slgD and its effects on growth regulation by anti-isotype antibodies
26. Lymphoma models for B cell activation and tolerance. V. Anti-Ig mediated growth inhibition is reversed by phorbol myristate acetate but does not involve changes in cytosofic free calcium
27. Antigen-induced lymphomagenesis: Identification of a murine B cell lymphoma with known antigen specificity
28. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phehyl-4H-l benzopyran-4-one (LY294002)
29. Phosphoinositide kinases
30. Steroid- and retinoidmediated growth arrest and apoptosis in WEHI-231 cells: Role of NF-κB, c-Myc and CKI p27(Kipl)
31. Cleavage of structural proteins daring the assembly of the head of bacteriophage T4
32. Phosphoinositide 3-kinase regulation of T cell receptor-mediated interleukin-2 gene expression in normal T cells
33. Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation
34. Quantitative chromatographic analysis of inositol phospholipids and related compounds
35. Evidence for two distinct phosphatidylinositol kinases in fibroblasts: Implications for cellular regulation
36. Association of phosphatidylinositol kinase activity with polyoma middle T competent for transformation
37. Phosphoinositide kinases
38. Specific regulation of c-myc oncogene expression in a murine B-cell lymphoma
39. Increased p27Kipl cyclin-dependent kinase inhibitor gene expression following anti-IgM treatment promotes apoptosis of WEHI 231 B cells
40. Myc and the cell cycle
41. Ribosomal S6 kinase signaling and the control of translation
42. Mitogenesis and protein synthesis: A role for ribosomal protein S6 phosphorylation?
43. Translational induction of the c-myc oncogene via activation of the FRAPFFOR signalling pathway
44. μ-Opioid receptor activates signaling pathways implicated in cell survival and translational control
45. Mechanisms and consequences of activation of protein kinase B/Akt
46. Phosphaitidylinositol-3-kinase activity is required for the anti-lg-mediated growth inhibition of a human B-lymphoma cell line
47. 1 CDKs in choroidal melanoma cells
48. Poly(ADP ribosyl)ation reactions in the regulation of nuclear functions
49. SH2 and SH3 domains in signal transduction
50. Signal transduction from the B cell antigen-receptor
51. 3H]-thymidine incorporation in neoplastic human B cells stimulated with antibodies to suŕface immunoglobulin
52. c-myc promotes survival of WEHI 231 B lymphoma cells from apoptosis
53. B-cell receptor and Fas-mediated signals for life and death
54. Signaling difference between class IgM and IgD antigen receptors
55. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
56. Cdc25 cell-cycle phosphatase as a target of c-myc
57. Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation
58. Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolyfic processing
59. Identification of CDK4 as a target of c-MYC
60. Rapid analysis of gene expression (RAGE) facilitates universal expression profiling