The Tissue Factor/Factor VIIa/Factor Xa Complex: A Model Built by Docking and Site-Directed Mutagenesis

Proteins: Structure, Function and Genetics

Volumn 53, Issue 3, 2003, Pages 640-648

  Norledge, Brian V ^a   Petrovan, Ramona J ^a   Ruf, Wolfram ^a   Olson, Arthur J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Blood coagulation; Factor VII; Factor X; Protein protein docking; Tissue factor

Indexed keywords

4 CARBOXYGLUTAMIC ACID; ASPARAGINE; ASPARTIC ACID; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 7A; EPIDERMAL GROWTH FACTOR; GLUTAMINE; LYSINE; MUTANT PROTEIN; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; THROMBOPLASTIN;

ANIMAL CELL; ARTICLE; BLOOD CLOTTING; CALCULATION; CARDIOVASCULAR DISEASE; CATALYSIS; CHO CELL; COMPLEX FORMATION; COMPUTER PROGRAM; COMPUTER SIMULATION; CONTROLLED STUDY; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CATALYTIC DOMAIN; EPIDERMAL GROWTH FACTOR; FACTOR VIIA; FACTOR XA; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; THROMBOPLASTIN;

EID: 0242362193     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.10445     Document Type: Article

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