Ca2+ binding to the first epidermal growth factor module of coagulation factor VIIa is important for cofactor interaction and proteolytic function

Journal of Biological Chemistry

Volumn 272, Issue 28, 1997, Pages 17467-17472

  Kelly, Curtis R ^a   Dickinson, Craig D ^a   Ruf, Wolfram ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 7A; CALCIUM ION; EPIDERMAL GROWTH FACTOR; 4 CARBOXYGLUTAMIC ACID; ALANINE; ASPARAGINE; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 9; CALCIUM; GLUTAMINE; GLYCINE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM BINDING; ESCHERICHIA COLI; INSECT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL; HAMSTER; KINETICS; METABOLISM; STRUCTURE ACTIVITY RELATION;

1-CARBOXYGLUTAMIC ACID; ALANINE; ANIMALS; ASPARAGINE; BINDING SITES; CALCIUM; CHO CELLS; CRICETINAE; EPIDERMAL GROWTH FACTOR; FACTOR IX; FACTOR VIIA; FACTOR X; GLUTAMINE; GLYCINE; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030610144     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.28.17467     Document Type: Article

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