-
1
-
-
0017222403
-
Sulindac: Clinical test of a new antiinflammatory agent in rheumatoid arthritis
-
Fasching U, Eberl R: Sulindac: Clinical test of a new antiinflammatory agent in rheumatoid arthritis. Wein Klin Wochenschr Suppl 1976;59:1-10.
-
(1976)
Wein Klin Wochenschr Suppl
, vol.59
, pp. 1-10
-
-
Fasching, U.1
Eberl, R.2
-
2
-
-
0020565187
-
Sulindac for polyposis of the colon
-
Waddell WR, Loughry RW: Sulindac for polyposis of the colon. J Surg Oncol 1983;24:83-87.
-
(1983)
J Surg Oncol
, vol.24
, pp. 83-87
-
-
Waddell, W.R.1
Loughry, R.W.2
-
4
-
-
0027197062
-
Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
-
Giardiello FM, Hamilton SR, Krush AJ, et al.: Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N Engl J Med 1993;328:1313-1316.
-
(1993)
N Engl J Med
, vol.328
, pp. 1313-1316
-
-
Giardiello, F.M.1
Hamilton, S.R.2
Krush, A.J.3
-
5
-
-
0037018508
-
Primary chemoprevention of familial adenomatous polyposis with sulindac
-
Giardiello FM, Yang VW, Hylind LM, et al.: Primary chemoprevention of familial adenomatous polyposis with sulindac. N Engl J Med 2002;346:1054-1059.
-
(2002)
N Engl J Med
, vol.346
, pp. 1054-1059
-
-
Giardiello, F.M.1
Yang, V.W.2
Hylind, L.M.3
-
6
-
-
0025834849
-
Sulindac causess regression of rectal polyps in familial adenomatous polyposis
-
Labayle D, Fischer D, Vielh P, et al.: Sulindac causess regression of rectal polyps in familial adenomatous polyposis. Gastroenterology 1991;101:635-639.
-
(1991)
Gastroenterology
, vol.101
, pp. 635-639
-
-
Labayle, D.1
Fischer, D.2
Vielh, P.3
-
7
-
-
0027141503
-
Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis
-
Nugent KP, Farmer KC, Spigelman AD, et al.: Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis. Br J Surg 1993;80:1618-1619.
-
(1993)
Br J Surg
, vol.80
, pp. 1618-1619
-
-
Nugent, K.P.1
Farmer, K.C.2
Spigelman, A.D.3
-
8
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
Steinbach G, Lynch PM, Phillips RKS, et al.: The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med 2000;342:1946-1952.
-
(2000)
N Engl J Med
, vol.342
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
Phillips, R.K.S.3
-
9
-
-
0037138743
-
Nonsteroidal anti-inflammatory drugs as anticancer agents: Mechanistic, pharmacologic, and clinical issues
-
Thun MJ, Henley SJ, Patrono C: Nonsteroidal anti-inflammatory drugs as anticancer agents: Mechanistic, pharmacologic, and clinical issues. J Natl Cancer Inst 2002;94:4.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 4
-
-
Thun, M.J.1
Henley, S.J.2
Patrono, C.3
-
11
-
-
0014664886
-
Release of additional factors in anaphylaxis and its antagonism by anti-inflammatory drugs
-
Piper PJ, Vane JR: Release of additional factors in anaphylaxis and its antagonism by anti-inflammatory drugs. Nature 1969;223:29-35.
-
(1969)
Nature
, vol.223
, pp. 29-35
-
-
Piper, P.J.1
Vane, J.R.2
-
12
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
-
Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971;231:232-235.
-
(1971)
Nat New Biol
, vol.231
, pp. 232-235
-
-
Vane, J.R.1
-
13
-
-
0034676492
-
A causal relationship between unscheduled eicosanoid signaling and tumor development: Cancer chemoprevention by inhibitors of arachidonic acid metabolism
-
Marks F, Muller-Decker K, Furstenberger G: A causal relationship between unscheduled eicosanoid signaling and tumor development: Cancer chemoprevention by inhibitors of arachidonic acid metabolism. Toxicology 2000;153:11-26.
-
(2000)
Toxicology
, vol.153
, pp. 11-26
-
-
Marks, F.1
Muller-Decker, K.2
Furstenberger, G.3
-
14
-
-
0020334145
-
2 production by suppressor monocytes in head and neck cancer patients
-
2 production by suppressor monocytes in head and neck cancer patients. Ann Surg 1982;196:645-650.
-
(1982)
Ann Surg
, vol.196
, pp. 645-650
-
-
Balch, C.M.1
Dougherty, P.A.2
Tilden, A.B.3
-
15
-
-
0017381619
-
Prostaglandins from tumour of human large bowel
-
Bennett A, Tacca MD, Stamford IF, et al.: Prostaglandins from tumour of human large bowel. Br J Cancer 1977;6:881-884.
-
(1977)
Br J Cancer
, vol.6
, pp. 881-884
-
-
Bennett, A.1
Tacca, M.D.2
Stamford, I.F.3
-
16
-
-
0016744070
-
Prostaglandins as mediators of hypercalcemia associated with certain types of cancer
-
Seyberth HW, Segre GV, Morgan JL, et al.: Prostaglandins as mediators of hypercalcemia associated with certain types of cancer. N Engl J Med 1975;293:1278-1283.
-
(1975)
N Engl J Med
, vol.293
, pp. 1278-1283
-
-
Seyberth, H.W.1
Segre, G.V.2
Morgan, J.L.3
-
18
-
-
0026761738
-
Aspirin and the potential role of prostaglandins in colon cancer
-
Marnett LJ: Aspirin and the potential role of prostaglandins in colon cancer. Cancer Res 1992;52:5575-5589.
-
(1992)
Cancer Res
, vol.52
, pp. 5575-5589
-
-
Marnett, L.J.1
-
19
-
-
0037178761
-
Connecting chromosomes, crisis, and cancer
-
Maser RS, DePinho RA, Connecting chromosomes, crisis, and cancer. Science 2002;297:565-569.
-
(2002)
Science
, vol.297
, pp. 565-569
-
-
Maser, R.S.1
DePinho, R.A.2
-
20
-
-
0036716140
-
A novel pathway of prostacyclin signaling-hanging out with nuclear receptors
-
Lim H, Dey SK: A novel pathway of prostacyclin signaling-hanging out with nuclear receptors. Endocrinology 2002;143:3207-3210.
-
(2002)
Endocrinology
, vol.143
, pp. 3207-3210
-
-
Lim, H.1
Dey, S.K.2
-
21
-
-
0033615352
-
PPARdelta is an APC-regulated target of nonsteroidal antiinflammatory drugs
-
He TC, Chan TA, Vogelstein B, et al.: PPARdelta is an APC-regulated target of nonsteroidal antiinflammatory drugs. Cell 1999;99:335-345.
-
(1999)
Cell
, vol.99
, pp. 335-345
-
-
He, T.C.1
Chan, T.A.2
Vogelstein, B.3
-
22
-
-
0035976575
-
Prostaglandins and leukotrienes: Advances in eicosanoid biology
-
Funk CD: Prostaglandins and leukotrienes: Advances in eicosanoid biology. Science 2001;294:1871-1875.
-
(2001)
Science
, vol.294
, pp. 1871-1875
-
-
Funk, C.D.1
-
23
-
-
0026322957
-
A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein
-
O'Banion MK, Sadowski HB, Winn V, et al.: A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein. J Biol Chem 1991;266:23261-23267.
-
(1991)
J Biol Chem
, vol.266
, pp. 23261-23267
-
-
O'Banion, M.K.1
Sadowski, H.B.2
Winn, V.3
-
24
-
-
0037078983
-
Lipid signals in pain control
-
Bazan NG, Flower RJ: Lipid signals in pain control. Nature 2002;420:135-138.
-
(2002)
Nature
, vol.420
, pp. 135-138
-
-
Bazan, N.G.1
Flower, R.J.2
-
25
-
-
0037108979
-
COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression
-
Chandrasekharan NV, Dai H, Roos KL, et al.: COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression. Proc Natl Acad Sci USA 2002;99:13371-13373.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13371-13373
-
-
Chandrasekharan, N.V.1
Dai, H.2
Roos, K.L.3
-
26
-
-
0033594963
-
Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target
-
Jakobsson PJ, Thoren S, Morgenstern R, et al.: Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci USA 1999;96:7220-7225.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7220-7225
-
-
Jakobsson, P.J.1
Thoren, S.2
Morgenstern, R.3
-
27
-
-
0028183018
-
IUP classification of prostanoid receptors: Properties, distribution, and structure of the receptors and their subtypes
-
Coleman RA, Smith WL, Narumya S: IUP classification of prostanoid receptors: Properties, distribution, and structure of the receptors and their subtypes. Pharm Rev 1994;46:205-229.
-
(1994)
Pharm Rev
, vol.46
, pp. 205-229
-
-
Coleman, R.A.1
Smith, W.L.2
Narumya, S.3
-
28
-
-
0034471496
-
Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia
-
Fosslein E: Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia. Crit Rev Clin Lab Sci 2000;37:431-502.
-
(2000)
Crit Rev Clin Lab Sci
, vol.37
, pp. 431-502
-
-
Fosslein, E.1
-
29
-
-
0032702213
-
Cyclooxygenase 2 inhibitors: Discovery, selectivity, and the future
-
Marnett LJ, Kalgutkar AS: Cyclooxygenase 2 inhibitors: Discovery, selectivity, and the future. TIPS 1999;20:465-469.
-
(1999)
TIPS
, vol.20
, pp. 465-469
-
-
Marnett, L.J.1
Kalgutkar, A.S.2
-
30
-
-
0035947709
-
Overexpression of cyclooxygenase-2 insufficient to induce tumorigenesis in transgenic mice
-
Liu CH, Chang SH, Narko K, et al.: Overexpression of cyclooxygenase-2 insufficient to induce tumorigenesis in transgenic mice. J Biol Chem 2001;276:18563-18569.
-
(2001)
J Biol Chem
, vol.276
, pp. 18563-18569
-
-
Liu, C.H.1
Chang, S.H.2
Narko, K.3
-
31
-
-
0034665122
-
The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis
-
Jacoby RF, Seibert K, Cole CE, et al.: The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. Cancer Res 2000;60:5040-5044.
-
(2000)
Cancer Res
, vol.60
, pp. 5040-5044
-
-
Jacoby, R.F.1
Seibert, K.2
Cole, C.E.3
-
32
-
-
0030606299
-
Suppression of intestinal polyposis in Apc delta knockout mice by inhibition of cyclooxygenase 2 (COX-2)
-
Oshima M, Dinchuk JE, Kargman SL, et al.: Suppression of intestinal polyposis in Apc delta knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996;87:803-809.
-
(1996)
Cell
, vol.87
, pp. 803-809
-
-
Oshima, M.1
Dinchuk, J.E.2
Kargman, S.L.3
-
34
-
-
0034161878
-
Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors
-
Masferrer JL, Leahy KM, Koki AT, et al.: Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Res 2000;60:1306-1311.
-
(2000)
Cancer Res
, vol.60
, pp. 1306-1311
-
-
Masferrer, J.L.1
Leahy, K.M.2
Koki, A.T.3
-
35
-
-
0032483712
-
Cyclooxygenase-2 inhibitors in tumorigenesis (part II)
-
Taketo MM: Cyclooxygenase-2 inhibitors in tumorigenesis (part II). J Natl Cancer Inst 1998;90:1609-1620.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1609-1620
-
-
Taketo, M.M.1
-
36
-
-
0036895867
-
Cyclooxygenase-2 expression in fibroblasts and endothelial cells of intestinal polyps
-
Sonoshita M, Takaku K, Oshima M, et al.: Cyclooxygenase-2 expression in fibroblasts and endothelial cells of intestinal polyps. Cancer Res 2002;62:6846-6849.
-
(2002)
Cancer Res
, vol.62
, pp. 6846-6849
-
-
Sonoshita, M.1
Takaku, K.2
Oshima, M.3
-
37
-
-
0034796261
-
Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc (Delta 716) knockout mice
-
Sonoshita M, Takaku K, Sasaki N, et al.: Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc (Delta 716) knockout mice. Nat Med 2001;7:1048-1051.
-
(2001)
Nat Med
, vol.7
, pp. 1048-1051
-
-
Sonoshita, M.1
Takaku, K.2
Sasaki, N.3
-
38
-
-
0032871514
-
Potential utility of COX-2 inhibitors in chemoprevention and chemotherapy
-
Koki AT, Leahy JM, Masferrer JL: Potential utility of COX-2 inhibitors in chemoprevention and chemotherapy. Exp Opin Invest Drugs 1999;8:1623-1638.
-
(1999)
Exp Opin Invest Drugs
, vol.8
, pp. 1623-1638
-
-
Koki, A.T.1
Leahy, J.M.2
Masferrer, J.L.3
-
40
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D, Folkman J: Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996;86:353-364.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
41
-
-
0036468287
-
Cyclooxygenase-2 inhibition by celecoxib reduces proliferafion and induces apoptosis in angiogenic endothelial cells in vivo
-
Leahy JM, Ornberg RL, Wang Y, et al.: Cyclooxygenase-2 inhibition by celecoxib reduces proliferafion and induces apoptosis in angiogenic endothelial cells in vivo. Cancer Res 2002;62:625-631.
-
(2002)
Cancer Res
, vol.62
, pp. 625-631
-
-
Leahy, J.M.1
Ornberg, R.L.2
Wang, Y.3
-
42
-
-
0028335192
-
Antiproliferative effect of nonsteroidal anti-inflammatory drugs against human colon cancer cells
-
Hixon LJ, Alaberts DX, Krutzsch M, et al.: Antiproliferative effect of nonsteroidal anti-inflammatory drugs against human colon cancer cells. Cancer Epidemiol Biomarkers Prev 1994;3:433-438.
-
(1994)
Cancer Epidemiol Biomarkers Prev
, vol.3
, pp. 433-438
-
-
Hixon, L.J.1
Alaberts, D.X.2
Krutzsch, M.3
-
43
-
-
0029035070
-
Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis
-
Piazza GA, Rahm AL, Krutzsch M, et al.: Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis. Cancer Res 1995;55:3110-3116.
-
(1995)
Cancer Res
, vol.55
, pp. 3110-3116
-
-
Piazza, G.A.1
Rahm, A.L.2
Krutzsch, M.3
-
44
-
-
0030968757
-
Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction
-
Piazza GA: Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction. Cancer Res 1997;57:2452-2459.
-
(1997)
Cancer Res
, vol.57
, pp. 2452-2459
-
-
Piazza, G.A.1
-
45
-
-
0030747817
-
Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels
-
Piazza GA, Alberts DS, Hixon LJ, et al.: Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels. Cancer Res 1997;57:2909-2915.
-
(1997)
Cancer Res
, vol.57
, pp. 2909-2915
-
-
Piazza, G.A.1
Alberts, D.S.2
Hixon, L.J.3
-
46
-
-
0035872448
-
Exisulind, a novel proapoptic drug, inhibits rat urinary bladder tumorgenesis
-
Piazza GA, Thompson WJ, Pamukcu R, et al.: Exisulind, a novel proapoptic drug, inhibits rat urinary bladder tumorgenesis. Cancer Res 2001;61:3961-3968.
-
(2001)
Cancer Res
, vol.61
, pp. 3961-3968
-
-
Piazza, G.A.1
Thompson, W.J.2
Pamukcu, R.3
-
47
-
-
0033588022
-
Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate
-
Brash AR: Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate. J Biol Chem 1999;274:23679-23682.
-
(1999)
J Biol Chem
, vol.274
, pp. 23679-23682
-
-
Brash, A.R.1
-
48
-
-
0035417925
-
Lipoxygenase modulation to reverse carcinogenesis
-
Shureiqi I, Lippman SM: Lipoxygenase modulation to reverse carcinogenesis. Cancer Res 2001;61:6307-6312.
-
(2001)
Cancer Res
, vol.61
, pp. 6307-6312
-
-
Shureiqi, I.1
Lippman, S.M.2
-
49
-
-
0034686624
-
15-LOX-1: A novel molecular target of non steroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells
-
Shureiqi I, Chen D, Lee JJ, et al.: 15-LOX-1: A novel molecular target of non steroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. J Natl Cancer Inst 2000;92:1136-1142.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1136-1142
-
-
Shureiqi, I.1
Chen, D.2
Lee, J.J.3
-
50
-
-
0034671921
-
15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells
-
Shureiqi I, Chen D, Lotan R, et al.: 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. Cancer Res 2000;60:6846-6850.
-
(2000)
Cancer Res
, vol.60
, pp. 6846-6850
-
-
Shureiqi, I.1
Chen, D.2
Lotan, R.3
-
51
-
-
0036184605
-
Treatment and prevention of intraepithelial neoplasia: An important target for accelerted new agent development: Recommendations of the American Association for Cancer Research Task Force on the Treatment and Prevention of Intraepithelial Neoplasia
-
O'Shaughnessy JA, Kelloff GJ, Gordon GB, et al.: Treatment and prevention of intraepithelial neoplasia: An important target for accelerted new agent development: Recommendations of the American Association for Cancer Research Task Force on the Treatment and Prevention of Intraepithelial Neoplasia. Clin Cancer Res 2002;8:314-346.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 314-346
-
-
O'Shaughnessy, J.A.1
Kelloff, G.J.2
Gordon, G.B.3
-
52
-
-
0036264626
-
New trends in dual 5-LOX/COX inhibition
-
Leval X, Julemont F, Delarge J, et al.: New trends in dual 5-LOX/COX inhibition. Curr Med Chem 2002;9:941-962.
-
(2002)
Curr Med Chem
, vol.9
, pp. 941-962
-
-
Leval, X.1
Julemont, F.2
Delarge, J.3
-
53
-
-
0032878590
-
A polymorphism of the methionine synthase gene: Association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk
-
Ma J, Stampfer MJ, Christensen B, et al.: A polymorphism of the methionine synthase gene: Association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 1999;8:825-829.
-
(1999)
Cancer Epidemiol Biomarkers Prev
, vol.8
, pp. 825-829
-
-
Ma, J.1
Stampfer, M.J.2
Christensen, B.3
|