7α- and 17α-substituted estrogens containing tridentate tricarbonyl rhenium/technetium complexes: Synthesis of estrogen receptor imaging agents and evaluation using microPET with technetium-94m

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 23, 2003, Pages 4977-4989

  Luyt, Leonard G ^a   Bigott, Heather M ^b   Welch, Michael J ^b   Katzenellenbogen, John A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17ALPHA [4',4' BIS(ETHANETHIO) 4' CARBOXYBUTYN 1' YL]ESTRA 1,3,5(10) TRIENE 3,17BETA DIOL RHENIUM TRICARBONYL; 17ALPHA [6',6' BIS(ETHANETHIO) 6' CARBOXYHEXYN 1' YL)ESTRA 1,3,5(10) TRIENE 3,17BETA DIOL RHENIUM TRICARBONYL; 7ALPHA [6 [N (ACETYLIMINO N' ACETIC ACID N' ETHYLTHIOETHYL)AMINO]HEXAN 1 YL]ESTRA 1,3,5(10) TRIENE 3,17BETA DIOL RHENIUM TRICARBONYL; 7ALPHA [6 [N (ACETYLIMINO N' ACETIC ACID N' ETHYLTHIOETHYL)AMINO]HEXAN 1 YL]ESTRA 1,3,5(10) TRIENE 3,17BETA DIOL TECHNETIUM TRICARBONYL; 7ALPHA [7 CARBOXY 7,7 BIS(ETHANETHIO)HEPTAN 1 YL]ESTRA 1,3,5(10) TRIENE 3,17BETA DIOL RHENIUM TRICARBONYL; CHELATE; ESTRADIOL; ESTRADIOL DERIVATIVE; ESTROGEN RECEPTOR; RADIOPHARMACEUTICAL AGENT; RHENIUM COMPLEX; TECHNETIUM COMPLEX; UNCLASSIFIED DRUG; ESTROGEN; RHENIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BREAST TUMOR; CHELATION; DISSECTION; DRUG BINDING; DRUG CONJUGATION; DRUG DESIGN; DRUG ELIMINATION; DRUG SCREENING; DRUG SYNTHESIS; DRUG UPTAKE; FEMALE; HUMAN; HUMAN CELL; ISOTOPE LABELING; LAMB; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT; STOMACH; SUBSTITUTION REACTION; TISSUE DISTRIBUTION; ANIMAL; CHEMISTRY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; MASS SPECTROMETRY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANIMALS; ESTROGENS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; ORGANOTECHNETIUM COMPOUNDS; RADIOPHARMACEUTICALS; RATS; RHENIUM; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0242266521     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2003.09.004     Document Type: Article

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