Dynamic visualization of a joint-specific autoimmune response through positron emission tomography

Nature Immunology

Volumn 3, Issue 4, 2002, Pages 366-372

  Wipke, Brian T ^a   Wang, Zheng ^a   Kim, Joonyoung ^a   McCarthy, Timothy J ^a,b   Allen, Paul M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; COPPER 64; GLUCOSE 6 PHOSPHATE ISOMERASE; IMMUNOGLOBULIN G;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ANTIGEN SPECIFICITY; ARTICLE; CIRCULATION; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; INFLAMMATION; INJECTION; KINETICS; MOUSE; MOUSE STRAIN; NONHUMAN; PASSIVE IMMUNIZATION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PURIFICATION; RHEUMATOID ARTHRITIS; TISSUE SPECIFICITY;

ANIMALS; ANKLE JOINT; ARTHRITIS, RHEUMATOID; AUTOANTIGENS; COPPER RADIOISOTOPES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE-6-PHOSPHATE ISOMERASE; HUMANS; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0036228519     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni775     Document Type: Article

References (33)

1. Organ-specific disease provoked by systemic autoimmunity
2. From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins
3. Genetic influences on the end-stage effector phase of arthritis
4. Molecular basis for recognition of an arthritic peptide and a foreign epitope on distinct MHC molecules by a single TCR
5. Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme
6. Comparative serum enzymology
7. The neurotrophic factor neuroleukin is 90% homologous with phosphohexose isomerase
8. Mouse glucose-6-phosphate isomerase and neuroleukin have identical 3′ sequences
9. Molecular cloning and expression of neuroleukin, a neurotrophic factor for spinal and sensory neurons
10. Tumor cell autocrine motility factor is the neuroleukin/phosphohexose isomerase polypeptide
11. The differentiation and maturation mediator for human myeloid leukemia cells shares homology with neuroleukin or phosphoglucose isomerase
12. Expression and secretion of neuroleukin/phosphohexose isomerase/maturation factor as autocrine motility factor by tumor cells
13. Autoantibodies to GPI in rheumatoid arthritis: Linkage between an animal model and human disease
14. PET: The merging of biology and imaging into molecular imaging
15. 64Cu using a biomedical cyclotron
16. An improved method for conjugating monoclonal antibodies with N-hydroxysulfosuccinimidyl DOTA
17. 123I-insulin. In vivo studies in rats
18. The use of radiolabeled nonspecific immunoglobulin in the detection of focal inflammation
19. How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease
20. Induction of erosive arthritis in mice after passive transfer of anti-type II collagen antibodies
21. Type II collagen-induced arthritis in rats. Passive transfer with serum and evidence that IgG anticollagen antibodies can cause arthritis
22. Autoimmunity to type II collagen: An experimental model of arthritis
23. Passive transfer studies with type II collagen antibody in B10.D2/old and new line and C57B1/6 normal and beige (Chediak-Higashi) strains: Evidence of important roles for C5 and multiple inflammatory cell types in the erosive arthritis
24. Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates
25. 125I-labeled antibody
26. Purification of human tumor cell autocrine motility factor and molecular cloning of its receptor
27. Expression of the AMF/neuroleukin receptor in developing and adult brain cerebellum
28. Immunologically induced acute synovitis in rabbits. Studies of immune complexes in synovial fluid
29. Imaging of inflammatory arthritis with technetium-99m-labeled IgG
30. Accumulation of immunoglobulin G at focal sites of inflammation
31. Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis
32. A facile, water-soluble method for modification of proteins with DOTA. Use of elevated temperature and optimized pH to achieve high specific activity and high chelate stability in radiolabeled immunoconjugates
33. Micropet-A high resolution pet scanner for imaging small animals