Oxygen-regulated expression of TGF-β3, a growth factor involved in trophoblast differentiation

Placenta

Volumn 24, Issue 10, 2003, Pages 941-950

  Schaffer L ^a   Scheid, A ^b   Spielmann, P ^c   Breymann, C ^a   Zimmermann, R ^a   Meuli, M ^b   Gassmann, M ^c   Marti, H H ^c   Wenger, R H ^d  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; GUANINE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IRON CHELATING AGENT; OXYGEN; TRANSFORMING GROWTH FACTOR BETA3;

5' UNTRANSLATED REGION; ANIMAL CELL; BINDING SITE; CELL DIFFERENTIATION; CONTROLLED STUDY; CPG ISLAND; EMBRYO; FEMALE; GC RICH SEQUENCE; GENE DELETION; GENE EXPRESSION REGULATION; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXYGEN TENSION; PLACENTA DEVELOPMENT; PREGNANCY DISORDER; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; REPORTER GENE; REVIEW; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; TROPHOBLAST;

EID: 0142243186     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0143-4004(03)00166-8     Document Type: Article

References (57)

1. Adams RL (1990) DNA methylation. The effect of minor bases on DNA-protein interactions. Biochem J, 265, 309-320.
2. Adelman DM, Gertsenstein M, Nagy A, Simon MC & Maltepe E (2000) Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses. Genes Dev, 14, 3191-3203.
3. Antequera F & Bird A (1999) CpG islands as genomic footprints of promoters that are associated with replication origins. Curr Biol, 9, R661-667.
4. Attwood JT, Yung RL & Richardson BC (2002) DNA methylation and the regulation of gene transcription. Cell Mol Life Sci, 59, 241-257.
5. Bruick RK & McKnight SL (2001) A conserved family of prolyl-4-hydroxylases that modify HIF. Science, 294, 1337-1340.
6. Burt DW, Paton IR & Dey BR (1991) Comparative analysis of human and chicken transforming growth factor-β2 and -β3 promoters. J Mol Endocrinol, 7, 175-183.
7. Camenisch G, Stroka DM, Gassmann M & Wenger RH (2001) Attenuation of HIF-1 DNA-binding activity limits hypoxia-inducible endothelin-1 expression. Eur J Physiol, 443, 240-249.
8. Camenisch G, Tini M, Chilov D, Kvietikova I, Srinivas V, Caro J, Spielmann P, Wenger RH & Gassmann M (1999) General applicability of chicken egg yolk antibodies: the performance of IgY immunoglobulins raised against the hypoxia-inducible factor 1a. FASEB J, 13, 81-88.
9. Caniggia I, Grisaru-Gravnosky S, Kuliszewsky M, Post M & Lye SJ (1999) Inhibition of TGF-β3 restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies. J Clin Invest, 103, 1641-1650.
10. Caniggia I, Mostachfi H, Winter J, Gassmann M, Lye SJ, Kuliszewski M & Post M (2000) Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3. J Clin Invest, 105, 577-587.
11. Cross JC (2000) Genetic insights into trophoblast differentiation and placental morphogenesis. Semin Cell Dev Biol, 11, 105-113.
12. De Marco CS & Caniggia I (2002) Mechanisms of oxygen sensing in human trophoblast cells. Placenta, 23, S58-68.
13. Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ & Ratcliffe PJ (2001) C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell, 107, 43-54.
14. Genbacev O, Zhou Y, Ludlow JW & Fisher SJ (1997) Regulation of human placental development by oxygen tension. Science, 277, 1669-1672.
15. Georgiades P, Ferguson-Smith AC & Burton GJ (2002) Comparative developmental anatomy of the murine and human definitive placentae. Placenta, 23, 3-19.
16. Gnarra JR, Ward JM, Porter FD, Wagner JR, Devor DE, Grinberg A, Emmert-Buck MR, Westphal H, Klausner RD & Linehan WM (1997) Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice. Proc Natl Acad Sci USA, 94, 9102-9107.
17. Graham CH, Hawley TS, Hawley RG, MacDougall JR, Kerbel RS, Khoo N & Lala PK (1993) Establishment and characterization of first trimester human trophoblast cells with extended lifespan. Exp Cell Res, 206, 204-211.
18. Hewitson KS, McNeill LA, Riordan MV, Tian YM, Bullock AN, Welford RW, Elkins JM, Oldham NJ, Bhattacharya S, Gleadle JM, Ratcliffe PJ, Pugh CW & Schofield CJ (2002) Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family. J Biol Chem, 277, 26351-26355.
19. 2 sensing. Science, 292, 464-468.
20. 2 homeostasis by hypoxia-inducible factor 1a. Genes Dev, 12, 149-162.
21. 2-regulated prolyl hydroxylation. Science, 292, 468-472.
22. Jakowlew S, Lechleider R, Geiser A, Kim S, Santa-Coloma T, Cubert J, Sporn M & Roberts A (1992) Identification and characterization of the chicken transforming growth factor-β3 promoter. Mol Endocrinol, 6, 1285-1298.
23. Jelkmann W (1992) Erythropoietin: structure, control of production, and function. Physiol Rev, 72, 449-489.
24. Jewell UR, Kvietikova I, Scheid A, Bauer C, Wenger RH & Gassmann M (2001) Induction of HIF-1α in response to hypoxia is instantaneous. FASEB J, 15, 1312-1314.
25. Katschinski DM, Le L, Heinrich D, Wagner KF, Hofer T, Schindler SG & Wenger RH (2002) Heat induction of the unphosphorylated form of hypoxia-inducible factor-1α is dependent on heat shock protein-90 activity. J Biol Chem, 277, 9262-9267.
26. Kvietikova I, Wenger RH, Marti HH & Gassmann M (1995) The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site. Nucl Acids Res, 23, 4542-4550.
27. Lafyatis R, Denhez F, Williams T, Sporn M & Roberts A (1991) Sequence specific protein binding to and activation of the TGF-β3 promoter through a repeated TCCC motif. Nucl Acids Res, 19, 6419-6425.
28. Lafyatis R, Lechleider R, Kim SJ, Jakowlew S, Roberts AB & Sporn MB (1990) Structural and functional characterization of the transforming growth factor β3 promoter. A cAMP-responsive element regulates basal and induced transcription. J Biol Chem, 265, 19128-19136.
29. Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML & Bruick RK (2002a) FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev, 16, 1466-1471.
30. Lando D, Peet DJ, Whelan DA, Gorman JJ & Whitelaw ML (2002b) Asparagine hydroxylation of the HIF transactivation domain: a hypoxic switch. Science, 295, 858-861.
31. Lennon DP, Edmison JM & Caplan AI (2001) Cultivation of rat marrow-derived mesenchymal stem cells in reduced oxygen tension: effects on in vitro and in vivo osteochondrogenesis. J Cell Physiol, 187, 345-355.
32. Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H & Wenger RH (2003) The antimycotic ciclopirox olamine induces HIF-1α stability, VEGF expression, and angiogenesis. FASEB J, 02-0586fje.
33. Mostafa SS, Miller WM & Papoutsakis ET (2000) Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes. Br J Haematol, 111, 879-889.
34. Rajakumar A & Conrad KP (2000) Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta. Biol Reprod, 63, 559-569.
35. Rajakumar A, Doty K, Daftary A, Harger G & Conrad KP (2003) Impaired oxygen-dependent reduction of HIF-1α and -2α proteins in pre-eclamptic placentae. Placenta, 24, 199-208.
36. Rajakumar A, Whitelock KA, Weissfeld LA, Daftary AR, Markovic N & Conrad KP (2001) Selective overexpression of the hypoxia-inducible transcription factor, HIF-2α, in placentas from women with preeclampsia. Biol Reprod, 64, 499-506.
37. Rapisarda A, Uranchimeg B, Scudiero DA, Selby M, Sausville EA, Shoemaker RH & Melillo G (2002) Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway. Cancer Res, 62, 4316-4324.
38. Risau W (1997) Mechanisms of angiogenesis. Nature, 386, 671-674.
39. Rolfs A, Kvietikova I, Gassmann M & Wenger RH (1997) Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1. J Biol Chem, 272, 20055-20062.
40. Rossant J & Cross JC (2001) Placental development: lessons from mouse mutants. Nat Rev Genet, 2, 538-548.
41. Ryan HE, Lo J & Johnson RS (1998) HIF-1α is required for solid tumor formation and embryonic vascularization. EMBO J, 17, 3005-3015.
42. Ryan HE, Poloni M, McNulty W, Elson D, Gassmann M, Arbeit JM & Johnson RS (2000) Hypoxia-inducible factor-1α is a positive factor in solid tumor growth. Cancer Res, 60, 4010-4015.
43. Scheid A, Wenger RH, Schaffer L, Camenisch I, Distler O, Ferenc A, Cristina H, Ryan HE, Johnson RS, Wagner KF, Stauffer UG, Bauer C, Gassmann M & Meuli M (2002) Physiologically low oxygen concentrations determined in fetal skin regulate hypoxia-inducible factor 1 and transforming growth factor-β3. FASEB J, 16, 411-413.
44. Simpson H, Robson SC, Bulmer JN, Barber A & Lyall F (2002) Transforming growth factor β expression in human placenta and placental bed during early pregnancy. Placenta, 23, 44-58.
45. Tate PH & Bird AP (1993) Effects of DNA methylation on DNA-binding proteins and gene expression. Curr Opin Genet Dev, 3, 226-231.
46. ten Dijke P, Hansen P, Iwata KK, Pieler C & Foulkes JG (1988) Identification of another member of the transforming growth factor type beta gene family. Proc Natl Acad Sci USA, 85, 4715-4719.
47. Tian H, Hammer RE, Matsumoto AM, Russell DW & McKnight SL (1998) The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes Dev, 12, 3320-3324.
48. Voss AK, Thomas T & Gruss P (2000) Mice lacking HSP90β fail to develop a placental labyrinth. Development, 127, 1-11.
49. 2 tension. Proc Natl Acad Sci USA, 92, 5510-5514.
50. Wang GL & Semenza GL (1993) Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction. Blood, 82, 3610-3615.
51. Wanner RM, Spielmann P, Stroka DM, Camenisch G, Camenisch I, Scheid A, Houck DR, Bauer C, Gassmann M & Wenger RH (2000) Epolones induce erythropoietin expression via hypoxia-inducible factor-1α activation. Blood, 96, 1558-1565.
52. 2-regulated gene expression. FASEB J, 16, 1151-1162.
53. Wenger RH, Camenisch G, Desbaillets I, Chilov D & Gassmann M (1998a) Up-regulation of hypoxia-inducible factor-1α is not sufficient for hypoxic/anoxic p53 induction. Cancer Res, 58, 5678-5680.
54. Wenger RH, Kvietikova I, Rolfs A, Camenisch G & Gassmann M (1998b) Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site. Eur J Biochem, 253, 771-777.
55. Wenger RH, Rolfs A, Spielmann P, Zimmermann DR & Gassmann M (1998c) Mouse hypoxia-inducible factor-1α is encoded by two different mRNA isoforms: expression from a tissue-specific and a housekeeping-type promoter. Blood, 91, 3471-3480.
56. Willam C, Masson N, Tian YM, Mahmood SA, Wilson MI, Bicknell R, Eckardt KU, Maxwell PH, Ratcliffe PJ & Pugh CW (2002) Peptide blockade of HIFα degradation modulates cellular metabolism and angiogenesis. Proc Natl Acad Sci USA, 99, 10423-10428.
57. Yun Z, Maecker HL, Johnson RS & Giaccia AJ (2002) Inhibition of PPARγ2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia. Dev Cell, 2, 331-341.