Peptide blockade of HIFα degradation modulates cellular metabolism and angiogenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 16, 2002, Pages 10423-10428

  Willam, Carsten ^a   Masson, Norma ^a   Tian, Ya Min ^a   Mahmood, S Aleema ^a   Wilson, Michael I ^a   Bicknell, Roy ^a,b   Eckardt, Kai Uwe ^a,c   Maxwell, Patrick H ^a   Ratcliffe, Peter J ^a   Pugh, Christopher W ^a  

^a Henry Wellcome Building for Genomic Medicine ^*  (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1; LIGASE; POLYPEPTIDE; TRANSACTIVATOR PROTEIN; HIF1A PROTEIN, HUMAN; HYBRID PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PEPTIDE; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE; VHL PROTEIN, HUMAN; VON HIPPEL LINDAU PROTEIN;

AMINO ACID SEQUENCE; ANGIOGENESIS; ARTICLE; CELL METABOLISM; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; HYDROXYLATION; HYPOXIA; ISCHEMIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; TRANSCRIPTION REGULATION; ANIMAL; BINDING SITE; C57BL MOUSE; CELL LINE; FEMALE; GENE EXPRESSION; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; REPORTER GENE; VASCULAR ENDOTHELIUM;

MURINAE;

ANIMALS; BINDING SITES; CELL LINE; ENDOTHELIUM, VASCULAR; FEMALE; GENE EXPRESSION; GENE PRODUCTS, TAT; GENES, REPORTER; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIGASES; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; PEPTIDES; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 0036667348     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.162119399     Document Type: Article

References (38)