-
1
-
-
0028899052
-
Performance of four different rat strains in the autoshaping, two-object discrimination and swim maze tests of learning and memory
-
Andrews JS, Jansen JHM, Linders S, Princen A, and Broekkamp CLE (1995) Performance of four different rat strains in the autoshaping, two-object discrimination and swim maze tests of learning and memory. Physiol Behav 57:785-790.
-
(1995)
Physiol Behav
, vol.57
, pp. 785-790
-
-
Andrews, J.S.1
Jansen, J.H.M.2
Linders, S.3
Princen, A.4
Broekkamp, C.L.E.5
-
2
-
-
0032907531
-
Investigation of stretching behaviour induced by the selective 5-HT6 receptor antagonist, Ro 04-6790, in rats
-
Bentley JC, Bourson A, Boess FG, Fone KC, Marsden CA, Petit N, and Sleight AJ (1999) Investigation of stretching behaviour induced by the selective 5-HT6 receptor antagonist, Ro 04-6790, in rats. Br J Pharmacol 126:1537-1542.
-
(1999)
Br J Pharmacol
, vol.126
, pp. 1537-1542
-
-
Bentley, J.C.1
Bourson, A.2
Boess, F.G.3
Fone, K.C.4
Marsden, C.A.5
Petit, N.6
Sleight, A.J.7
-
3
-
-
0030880426
-
Interaction of tryptamine and ergoline compounds with threonine 196 in the ligand binding site of the 5-hydroxytryptamine6 receptor
-
Boess FG, Monsma FJ Jr, Meyer V, Zwingelstein C, and Sleight AJ (1997) Interaction of tryptamine and ergoline compounds with threonine 196 in the ligand binding site of the 5-hydroxytryptamine6 receptor. Mol Pharmacol 52:515-523.
-
(1997)
Mol Pharmacol
, vol.52
, pp. 515-523
-
-
Boess, F.G.1
Monsma F.J., Jr.2
Meyer, V.3
Zwingelstein, C.4
Sleight, A.J.5
-
4
-
-
0031722106
-
Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor
-
Boess FG, Monsma FJ Jr, and Sleight AJ (1998) Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor. J Neurochem 71:2169-2177.
-
(1998)
J Neurochem
, vol.71
, pp. 2169-2177
-
-
Boess, F.G.1
Monsma F.J., Jr.2
Sleight, A.J.3
-
5
-
-
0035246514
-
5-HT(6) receptor antagonists: Lead optimisation and biological evaluation of N-aryl and N-heteroaryl 4-amino-benzene sulfonamides
-
Bos M, Sleight AJ, Godel T, Martin JR, Riemer C, and Stadler H (2001) 5-HT(6) receptor antagonists: lead optimisation and biological evaluation of N-aryl and N-heteroaryl 4-amino-benzene sulfonamides. Eur J Med Chem 36:165-178.
-
(2001)
Eur J Med Chem
, vol.36
, pp. 165-178
-
-
Bos, M.1
Sleight, A.J.2
Godel, T.3
Martin, J.R.4
Riemer, C.5
Stadler, H.6
-
6
-
-
0031593618
-
Involvement of 5-HT6 receptors in nigro-striatal function in rodents
-
Bourson A, Boess FG, Bos M, and Sleight AJ (1998) Involvement of 5-HT6 receptors in nigro-striatal function in rodents. Br J Pharmacol 125:1562-1566.
-
(1998)
Br J Pharmacol
, vol.125
, pp. 1562-1566
-
-
Bourson, A.1
Boess, F.G.2
Bos, M.3
Sleight, A.J.4
-
7
-
-
0028981113
-
Determination of the role of the 5-HT(6) receptor in the rat brain: A study using antisense oligonucleotides
-
Bourson A, Borroni E, Austin RH, Monsma FJ Jr, and Sleight AJ (1995) Determination of the role of the 5-HT(6) receptor in the rat brain: a study using antisense oligonucleotides. J Pharmacol Exp Ther 274:173-180.
-
(1995)
J Pharmacol Exp Ther
, vol.274
, pp. 173-180
-
-
Bourson, A.1
Borroni, E.2
Austin, R.H.3
Monsma F.J., Jr.4
Sleight, A.J.5
-
8
-
-
0027298969
-
Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats
-
Daly DA and Moghaddam B (1993) Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats. Neurosci Lett 152:61-64.
-
(1993)
Neurosci Lett
, vol.152
, pp. 61-64
-
-
Daly, D.A.1
Moghaddam, B.2
-
9
-
-
0034098959
-
In vivo effects of the 5-HT(6) antagonist SB-271046 on striatal and frontal cortex extracellular concentrations of noradrenaline, dopamine, 5-HT, glutamate and aspartate
-
Dawson LA, Nguyen HQ, and Li P (2000) In vivo effects of the 5-HT(6) antagonist SB-271046 on striatal and frontal cortex extracellular concentrations of noradrenaline, dopamine, 5-HT, glutamate and aspartate. Br J Pharmacol 130:23-26.
-
(2000)
Br J Pharmacol
, vol.130
, pp. 23-26
-
-
Dawson, L.A.1
Nguyen, H.Q.2
Li, P.3
-
10
-
-
0034782825
-
The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus
-
Dawson LA, Nguyen HQ, and Li P (2001) The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus. Neuropsychopharmacology 25:662-668.
-
(2001)
Neuropsychopharmacology
, vol.25
, pp. 662-668
-
-
Dawson, L.A.1
Nguyen, H.Q.2
Li, P.3
-
11
-
-
0036707514
-
5-HT6 receptor binding sites in schizophrenia and following antipsychotic drug administration: Autoradiographic studies with [125I]SB-258585
-
East SZ, Burnet PW, Leslie RA, Roberts JC, and Harrison PJ (2002) 5-HT6 receptor binding sites in schizophrenia and following antipsychotic drug administration: autoradiographic studies with [125I]SB-258585. Synapse 45:191-199.
-
(2002)
Synapse
, vol.45
, pp. 191-199
-
-
East, S.Z.1
Burnet, P.W.2
Leslie, R.A.3
Roberts, J.C.4
Harrison, P.J.5
-
12
-
-
0033609543
-
Effects of clozapine and haloperidol on 5-HT6 receptor mRNA levels in rat brain
-
Frederick JA and Meador-Woodruff JH (1999) Effects of clozapine and haloperidol on 5-HT6 receptor mRNA levels in rat brain. Schizophr Res 38:7-12.
-
(1999)
Schizophr Res
, vol.38
, pp. 7-12
-
-
Frederick, J.A.1
Meador-Woodruff, J.H.2
-
13
-
-
0035919145
-
Cloning of the mouse 5-HT6 serotonin receptor and mutagenesis studies of the third cytoplasmic loop
-
Kohen R, Fashingbauer LA, Heidmann DE, Guthrie CR, and Hamblin MW (2001) Cloning of the mouse 5-HT6 serotonin receptor and mutagenesis studies of the third cytoplasmic loop. Brain Res Mol Brain Res 90:110-117.
-
(2001)
Brain Res Mol Brain Res
, vol.90
, pp. 110-117
-
-
Kohen, R.1
Fashingbauer, L.A.2
Heidmann, D.E.3
Guthrie, C.R.4
Hamblin, M.W.5
-
14
-
-
0031881937
-
The structure and signalling properties of 5-HT receptors: An endless diversity?
-
Martin GR, Eglen RM, Hamblin MW, Hoyer D, and Yocca F (1998) The structure and signalling properties of 5-HT receptors: an endless diversity? Trends Pharmacol Sci 19:2-4.
-
(1998)
Trends Pharmacol Sci
, vol.19
, pp. 2-4
-
-
Martin, G.R.1
Eglen, R.M.2
Hamblin, M.W.3
Hoyer, D.4
Yocca, F.5
-
15
-
-
0035863032
-
Lack of association between the T→C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia
-
Masellis M, Basile VS, Meltzer HY, Lieberman JA, Sevy S, Goldman DA, Hamblin MW, Macciardi FM, and Kennedy JL (2001) Lack of association between the T→C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia. Schizophr Res 47:49-58.
-
(2001)
Schizophr Res
, vol.47
, pp. 49-58
-
-
Masellis, M.1
Basile, V.S.2
Meltzer, H.Y.3
Lieberman, J.A.4
Sevy, S.5
Goldman, D.A.6
Hamblin, M.W.7
Macciardi, F.M.8
Kennedy, J.L.9
-
16
-
-
0032977410
-
The effects of clozapine, risperidone and olanzapine on cognitive function in schizophrenia
-
Meltzer HY and McGurk SR (1999) The effects of clozapine, risperidone and olanzapine on cognitive function in schizophrenia. Schizophr Bull 25:233-255.
-
(1999)
Schizophr Bull
, vol.25
, pp. 233-255
-
-
Meltzer, H.Y.1
McGurk, S.R.2
-
17
-
-
0035825243
-
Effects of the 5-HT(6) receptor antagonist Ro 04-6790 on learning consolidation
-
Meneses A (2001) Effects of the 5-HT(6) receptor antagonist Ro 04-6790 on learning consolidation. Behav Brain Res 118:107-110.
-
(2001)
Behav Brain Res
, vol.118
, pp. 107-110
-
-
Meneses, A.1
-
18
-
-
0027481384
-
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs
-
Monsma FJ Jr, Shen Y, Ward RP, Hamblin MW, and Sibley DR (1993) Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Mol Pharmacol 43:320-327.
-
(1993)
Mol Pharmacol
, vol.43
, pp. 320-327
-
-
Monsma F.J., Jr.1
Shen, Y.2
Ward, R.P.3
Hamblin, M.W.4
Sibley, D.R.5
-
19
-
-
0035823425
-
Novel polymorphism in the 5′-upstream region of the human 5-HT6 receptor gene and schizophrenia
-
Ohmori O, Shinkai T, Hori H, and Nakamura J (2001) Novel polymorphism in the 5′-upstream region of the human 5-HT6 receptor gene and schizophrenia. Neurosci Lett 310:17-20.
-
(2001)
Neurosci Lett
, vol.310
, pp. 17-20
-
-
Ohmori, O.1
Shinkai, T.2
Hori, H.3
Nakamura, J.4
-
20
-
-
0037204855
-
Association study of the 5-hydroxytryptamine(6) receptor gene in Alzheimer's disease
-
Orlacchio A, Kawarai T, Paciotti E, Stefani A, Orlacchio A, Sorbi S, George-Hyslop PH, and Bernardi G (2002) Association study of the 5-hydroxytryptamine(6) receptor gene in Alzheimer's disease. Neurosci Lett 325:13-16.
-
(2002)
Neurosci Lett
, vol.325
, pp. 13-16
-
-
Orlacchio, A.1
Kawarai, T.2
Paciotti, E.3
Stefani, A.4
Orlacchio, A.5
Sorbi, S.6
George-Hyslop, P.H.7
Bernardi, G.8
-
21
-
-
0034095251
-
Neuropsychological change in early phase schizophrenia during 12 months of treatment with olanzapine, risperidone, or haloperidol
-
The Canadian Collaborative Group for Research in Schizophrenia
-
Purdon SE, Jones BD, Stip E, Labelle A, Addington D, David SR, Breier A, and Tollefson GD (2000) Neuropsychological change in early phase schizophrenia during 12 months of treatment with olanzapine, risperidone, or haloperidol. The Canadian Collaborative Group for Research in Schizophrenia. Arch Gen Psychiatry 57:249-258.
-
(2000)
Arch Gen Psychiatry
, vol.57
, pp. 249-258
-
-
Purdon, S.E.1
Jones, B.D.2
Stip, E.3
Labelle, A.4
Addington, D.5
David, S.R.6
Breier, A.7
Tollefson, G.D.8
-
22
-
-
0035154738
-
The therapeutic potential of 5-HT6 receptor antagonists
-
Reavill C and Rogers DC (2001) The therapeutic potential of 5-HT6 receptor antagonists. Curr Opin Investig Drugs 2:104-109.
-
(2001)
Curr Opin Investig Drugs
, vol.2
, pp. 104-109
-
-
Reavill, C.1
Rogers, D.C.2
-
23
-
-
0034740154
-
5-HT6 receptor antagonists enhance retention of a water maze task in the rat
-
Rogers DC and Hagan JJ (2001) 5-HT6 receptor antagonists enhance retention of a water maze task in the rat. Psychopharmacology 158:114-119.
-
(2001)
Psychopharmacology
, vol.158
, pp. 114-119
-
-
Rogers, D.C.1
Hagan, J.J.2
-
25
-
-
0033854822
-
Characterization of SB-271046: A potent, selective and orally active 5-HT(6) receptor antagonist
-
Routledge C, Bromidge SM, Moss SF, Price GW, Hirst W, Newman H, Riley G, Gager T, Stean T, Upton N, et al. (2000) Characterization of SB-271046: a potent, selective and orally active 5-HT(6) receptor antagonist. Br J Pharmacol 130:1606-1612.
-
(2000)
Br J Pharmacol
, vol.130
, pp. 1606-1612
-
-
Routledge, C.1
Bromidge, S.M.2
Moss, S.F.3
Price, G.W.4
Hirst, W.5
Newman, H.6
Riley, G.7
Gager, T.8
Stean, T.9
Upton, N.10
-
26
-
-
0027212940
-
A novel rat serotonin (5-HT6) receptor: Molecular cloning, localization and stimulation of cAMP accumulation
-
Ruat M, Traiffort E, Arrang JM, Tardivel-Lacombe J, Diaz J, Leurs R, and Schwartz JC (1993) A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation. Biochem Biophys Res Commun 193:268-276.
-
(1993)
Biochem Biophys Res Commun
, vol.193
, pp. 268-276
-
-
Ruat, M.1
Traiffort, E.2
Arrang, J.M.3
Tardivel-Lacombe, J.4
Diaz, J.5
Leurs, R.6
Schwartz, J.C.7
-
27
-
-
0036597204
-
Memories are made of this (perhaps): A review of serotonin 5-HT(6) receptor ligands and their biological functions
-
Russell MG and Dias R (2002) Memories are made of this (perhaps): a review of serotonin 5-HT(6) receptor ligands and their biological functions. Curr Top Med Chem 2:643-654.
-
(2002)
Curr Top Med Chem
, vol.2
, pp. 643-654
-
-
Russell, M.G.1
Dias, R.2
-
28
-
-
0028670359
-
5-HT6 receptors positively coupled to adenylyl cyclase in striatal neurones in culture
-
Sebben M, Ansanay H, Bockaert J, and Dumuis A (1994) 5-HT6 receptors positively coupled to adenylyl cyclase in striatal neurones in culture. Neuroreport 5:2553-2557.
-
(1994)
Neuroreport
, vol.5
, pp. 2553-2557
-
-
Sebben, M.1
Ansanay, H.2
Bockaert, J.3
Dumuis, A.4
-
29
-
-
0033574643
-
Association study of the 5-HT6 receptor gene in schizophrenia
-
Shinkai T, Ohmori O, Kojima H, Terao T, Suzuki T, and Abe K (1999) Association study of the 5-HT6 receptor gene in schizophrenia. Am J Med Genet 88:120-122.
-
(1999)
Am J Med Genet
, vol.88
, pp. 120-122
-
-
Shinkai, T.1
Ohmori, O.2
Kojima, H.3
Terao, T.4
Suzuki, T.5
Abe, K.6
-
30
-
-
0036201186
-
Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat
-
Shirazi-Southall S, Rodriguez DE, and Nomikos GG (2002) Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat. Neuropsychopharmacology 26:583-594.
-
(2002)
Neuropsychopharmacology
, vol.26
, pp. 583-594
-
-
Shirazi-Southall, S.1
Rodriguez, D.E.2
Nomikos, G.G.3
-
31
-
-
0031748656
-
Characterization of Ro 04-6790 and Ro 63-0563: Potent and selective antagonists at human and rat 5-HT6 receptors
-
Sleight AJ, Boess FG, Bos M, Levet-Trafit B, Riemer C, and Bourson A (1998) Characterization of Ro 04-6790 and Ro 63-0563: potent and selective antagonists at human and rat 5-HT6 receptors. Br J Pharmacol 124:556-562.
-
(1998)
Br J Pharmacol
, vol.124
, pp. 556-562
-
-
Sleight, A.J.1
Boess, F.G.2
Bos, M.3
Levet-Trafit, B.4
Riemer, C.5
Bourson, A.6
-
33
-
-
0036125527
-
Pharmacological profile of SB-357134: A potent, selective, brain penetrant and orally active 5-HT(6) receptor antagonist
-
Stean TO, Hirst WD, Thomas DR, Price GW, Rogers D, Riley G, Bromidge SM, Serafinowska HT, Smith DR, Bartlett S, et al. (2002) Pharmacological profile of SB-357134: a potent, selective, brain penetrant and orally active 5-HT(6) receptor antagonist. Pharmacol Biochem Behav 71:645-654.
-
(2002)
Pharmacol Biochem Behav
, vol.71
, pp. 645-654
-
-
Stean, T.O.1
Hirst, W.D.2
Thomas, D.R.3
Price, G.W.4
Rogers, D.5
Riley, G.6
Bromidge, S.M.7
Serafinowska, H.T.8
Smith, D.R.9
Bartlett, S.10
-
34
-
-
0034749093
-
Association analysis of HTR6 and HTR2A polymorphisms in sporadic Alzheimer's disease
-
Thome J, Retz W, Baader M, Pesold B, Hu M, Cowen M, Durany N, Adler G, Henn FA, and Rosler M (2001) Association analysis of HTR6 and HTR2A polymorphisms in sporadic Alzheimer's disease. J Neural Transm 108:1175-1180.
-
(2001)
J Neural Transm
, vol.108
, pp. 1175-1180
-
-
Thome, J.1
Retz, W.2
Baader, M.3
Pesold, B.4
Hu, M.5
Cowen, M.6
Durany, N.7
Adler, G.8
Henn, F.A.9
Rosler, M.10
-
35
-
-
0033587801
-
Association study of serotonin-6 receptor variant (C267T) with schizophrenia and aggressive behavior
-
Tsai SJ, Chiu HJ, Wang YC, and Hong CJ (1999a) Association study of serotonin-6 receptor variant (C267T) with schizophrenia and aggressive behavior. Neurosci Lett 271:135-137.
-
(1999)
Neurosci Lett
, vol.271
, pp. 135-137
-
-
Tsai, S.J.1
Chiu, H.J.2
Wang, Y.C.3
Hong, C.J.4
-
36
-
-
0032699136
-
Association analysis of the 5-HT6 receptor polymorphism C267T in Alzheimer's disease
-
Tsai SJ, Liu HC, Liu TY, Wang YC, and Hong CJ (1999b) Association analysis of the 5-HT6 receptor polymorphism C267T in Alzheimer's disease. Neurosci Lett 276:138-139.
-
(1999)
Neurosci Lett
, vol.276
, pp. 138-139
-
-
Tsai, S.J.1
Liu, H.C.2
Liu, T.Y.3
Wang, Y.C.4
Hong, C.J.5
-
37
-
-
0034599555
-
Investigation of the human serotonin 6 [5-HT6] receptor gene in bipolar affective disorder and schizophrenia
-
Vogt IR, Shimron-Abarbanell D, Neidt H, Erdmann J, Cichon S, Schulze TG, Muller DJ, Maier W, Albus M, Borrmann-Hassenbach M, et al. (2000) Investigation of the human serotonin 6 [5-HT6] receptor gene in bipolar affective disorder and schizophrenia. Am J Med Genet 96:217-221.
-
(2000)
Am J Med Genet
, vol.96
, pp. 217-221
-
-
Vogt, I.R.1
Shimron-Abarbanell, D.2
Neidt, H.3
Erdmann, J.4
Cichon, S.5
Schulze, T.G.6
Muller, D.J.7
Maier, W.8
Albus, M.9
Borrmann-Hassenbach, M.10
-
38
-
-
0034742606
-
A role for 5-HT(6) receptors in retention of spatial learning in the Morris water maze
-
Woolley ML, Bentley JC, Sleight AJ, Marsden CA, and Fone KC (2001) A role for 5-HT(6) receptors in retention of spatial learning in the Morris water maze. Neuropharmacology 41:210-219.
-
(2001)
Neuropharmacology
, vol.41
, pp. 210-219
-
-
Woolley, M.L.1
Bentley, J.C.2
Sleight, A.J.3
Marsden, C.A.4
Fone, K.C.5
-
39
-
-
0032571283
-
Central distribution and function of 5-HT6 receptor subtype in the rat brain
-
Yoshioka M, Matsumoto M, Togashi H, Mori K, and Saito H (1998) Central distribution and function of 5-HT6 receptor subtype in the rat brain. Life Sci 62:1473-1477.
-
(1998)
Life Sci
, vol.62
, pp. 1473-1477
-
-
Yoshioka, M.1
Matsumoto, M.2
Togashi, H.3
Mori, K.4
Saito, H.5
|