A role of P301L tau mutant in anti-apoptotic gene expression, cell cycle and apoptosis

Molecular and Cellular Neuroscience

Volumn 24, Issue 2, 2003, Pages 367-379

  Zhao, Z ^a   Ho, L ^a   Suh, J ^a   Qin, W ^a   Pyo, H ^a   Pompl, P ^a   Ksiezak Reding, H ^a   Pasinetti, G M ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; PROLINE DERIVATIVE; REGULATOR PROTEIN; SURVIVIN; TAU PROTEIN;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL DEATH; CELL LINE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE CLUSTER; GENE EXPRESSION; HUMAN; HUMAN CELL; METAPHASE; MISSENSE MUTATION; MITOSIS SPINDLE; NEUROBLASTOMA CELL; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; TAUOPATHY; WILD TYPE;

INTRACISTERNAL A-PARTICLES;

EID: 0142219833     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-7431(03)00175-1     Document Type: Article

References (52)

1. Adida C., Crotty P.L., McGrath J., Berrebi D., Diebold J., Altieri D.C. Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation. Am. J. Pathol. 152:1998;43-49.
2. Ambrosini G., Adida C., Altieri D.C. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat. Med. 3:1997;917-921.
3. Barghorn S., Zheng-Fischhofer Q., Ackmann M., Biernat J., von Bergen M., Mandelkow E.M., Mandelkow E. Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias. Biochemistry. 39:2000;11714-11721.
4. Blagosklonny M.V. A node between proliferation, apoptosis, and growth arrest. Bioessays. 21:1999;704-709.
5. Bowser R., Smith M.A. Cell cycle proteins in Alzheimer's disease plenty of wheels but no cycle . J. Alzheimers Dis. 4:2002;249-254.
6. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
7. Clark L.N., Poorkaj P., Wszolek Z., Geschwind D.H., Nasreddine Z.S., Miller B., Li D., Payami H., Awert F., Markopoulou K., Andreadis A., D'Souza I., Lee V.M., Reed L., Trojanowski J.Q., Zhukareva V., Bird T., Schellenberg G., Wilhelmsen K.C. Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17. Proc. Natl. Acad. Sci. USA. 95:1998;13103-13107.
8. Deveraux Q.L., Reed J.C. IAP family proteins suppressors of apoptosis . Genes Dev. 13:1999;239-252.
9. Deveraux Q.L., Takahashi R., Salvesen G.S., Reed J.C. X-linked IAP is a direct inhibitor of cell-death proteases. Nature. 388:1997;300-304.
10. D'Mello S.R. Molecular regulation of neuronal apoptosis. Curr. Top. Dev. Biol. 39:1998;187-213.
11. Drewes G., Lichtenberg-Kraag B., Doring F., Mandelkow E.M., Biernat J., Goris J., Doree M., Mandelkow E. Mitogen activated protein (MAP) kinase transforms tau protein into an Alzhemer-like state. EMBO J. 11:1992;2131-2138.
12. D'Souza I., Poorkaj P., Hong M., Nochlin D., Lee V.M., Bird T.D., Schellenberg G.D. Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements. Proc. Natl. Acad. Sci. USA. 96:1999;5598-5603.
13. Feany M.B., Dickson D.W. Neurodegenerative disorders with extensive tau pathology a comparative study and review . Ann. Neurol. 40:1996;139-148.
14. Goedert M., Crowther R.A., Spillantini M.G. Tau mutations cause frontotemporal dementias. Neuron. 21:1998;955-958.
15. Gotz J., Chen F., Barmettler R., Nitsch R.M. Tau filament formation in transgenic mice expressing P301L tau. J. Biol. Chem. 276:2001;529-534.
16. Higuchi M., Ishihara T., Zhang B., Hong M., Andreadis A., Trojanowski J., Lee V.M. Transgenic mouse model of tauopathies with glial pathology and nervous system degeneration. Neuron. 35:2002;433-446.
17. Ho L., Pieroni C., Winger D., Purohit D.P., Aisen P.S., Pasinetti G.M. Regional distribution of cyclooxygenase-2 in the hippocampal formation in Alzheimer's disease. J. Neurosci. Res. 57:1999;295-303.
18. Ho L., Xiang Z., Mukherjee P., Zhang W., De Jesus N., Mirjany M., Yemul S., Pasinetti G.M. Gene expression profiling of the tau mutant (P301L) transgenic mouse brain. Neurosci. Lett. 310:2001;1-4.
19. Holcik M., Thompson C.S., Yaraghi Z., Lefebvre C.A., MacKenzie A.E., Korneluk R.G. The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury. Proc. Natl. Acad. Sci. USA. 97:2000;2286-2290.
20. Hong M., Zhukareva V., Vogelsberg-Ragaglia V., Wszolek Z., Reed L., Miller B.I., Geschwind D.H., Bird T.D., McKeel D., Goate A., Morris J.C., Wilhelmsen K.C., Schellenberg G.D., Trojanowski J.Q., Lee V.M. Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17. Science. 282:1998;1914-1917.
21. Husseman J.W., Nochlin D., Vincent I. Mitotic activation a convergent mechanism for a cohort of neurodegenerative diseases . Neurobiol. Aging. 21:2000;815-828.
22. Hutton M., Lendon C.L., Rizzu P., Baker M., Froelich S., Houlden H., Pickering-Brown S., Chakraverty S., Isaacs A., Grover A., Hackett J., Adamson J., Lincoln S., Dickson D., Davies P., Petersen R.C., Stevens M., de Graaff E., Wauters E., van Baren J., Hillebrand M., Joosse M., Kwon J.M., Nowotny P., Heutink P. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17. Nature. 393:1998;702-705.
23. Iijima M., Tabira T., Poorkaj P., Schellenberg G.D., Trojanowski J.Q., Lee V.M., Schmidt M.L., Takahashi K., Nabika T., Matsumoto T., Yamashita Y., Yoshioka S., Ishino H. A distinct familial presenile dementia with a novel missense mutation in the tau gene. NeuroReport. 10:1999;497-501.
24. Illenberger S., Zheng-Fischhofer Q., Preuss U., Stamer K., Baumann K., Trinczek B., Biernat J., Godemann R., Mandelkow E.M., Mandelkow E. The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells implications for Alzheimer's disease . Mol. Biol. Cell. 9:1998;1495-1512.
25. Johnson D.G., Walker C.L. Cyclins and cell cycle checkpoints. Annu. Rev. Pharmacol. Toxicol. 39:1999;295-312.
26. Jordan M.A., Wilson L. Microtubules and actin filaments dynamic targets for cancer chemotherapy . Curr. Opin. Cell Biol. 10:1998;123-130.
27. Kugler S., Straten G., Kreppel F., Isenmann S., Liston P., Bahr M. The X-linked inhibitor of apoptosis (XIAP) prevents cell death in axotomized CNS neurons in vivo. Cell Death. Differ. 7:2000;815-824.
28. Lee V.M., Goedert M., Trojanowski J.Q. Neurodegenerative tauopathies. Annu. Rev. Neurosci. 24:2001;1121-1159.
29. Lee V.M., Trojanowski J.Q. Transgenic mouse models of tauopathies prospects for animal models of Pick's disease . Neurology. 56:2001;S26-S30.
30. Levkau B., Garton K.J., Ferri N., Kloke K., Nofer J.R., Baba H.A., Raines E.W., Breithardt G. xIAP induces cell-cycle arrest and activates nuclear factor-kappaB new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells . Circ. Res. 88:2001;282-290.
31. Lewis J., McGowan E., Rockwood J., Melrose H., Nacharaju P., van Slegtenhorst M., Gwinn-Hardy K., Paul M.M., Baker M., Yu X., Duff K., Hardy J., Corral A., Lin W.L., Yen S.H., Dickson D.W., Davies P., Hutton M. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat. Genet. 25:2000;402-405.
32. Li F., Ackermann E.J., Bennett C.F., Rothermel A.L., Plescia J., Tognin S., Villa A., Marchisio P.C., Altieri D.C. Pleiotropic cell-division defects and apoptosis induced by interference with survivin function. Nat. Cell Biol. 1:1999;461-466.
33. Li F., Ambrosini G., Chu E.Y., Plescia J., Tognin S., Marchisio P.C., Altieri D.C. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature. 396:1998;580-584.
34. Lin W.L., Lewis J., Yen S.H., Hutton M., Dickson D.W. Filamentous tau in oligodendrocytes and astrocytes of transgenic mice expressing the human tau isoform with the P301L mutation. Am. J. Pathol. 162:2003;213-218.
35. Nyberg-Hoffman C., Shabram P., Li W., Giroux D., Aguilar-Cordova E. Sensitivity and reproducibility in adenoviral infectious titer determination. Nat. Med. 3:1997;808-811.
36. O'Connor D.S., Wall N.R., Porter A.C., Altieri D.C. A p34(cdc2) survival checkpoint in cancer. Cancer Cell. 2:2002;43-54.
37. Perrelet D., Ferri A., MacKenzie A.E., Smith G.M., Korneluk R.G., Liston P., Sagot Y., Terrado J., Monnier D., Kato A.C. IAP family proteins delay motoneuron cell death in vivo. Eur. J. Neurosci. 12:2000;2059-2067.
38. Poorkaj P., Bird T.D., Wijsman E., Nemens E., Garruto R.M., Anderson L., Andreadis A., Wiederholt W.C., Raskind M., Schellenberg G.D. Tau is a candidate gene for chromosome 17 frontotemporal dementia. Ann. Neurol. 43:1998;815-825.
39. Preuss U., Doring F., Illenberger S., Mandelkow E.M. Cell cycle-dependent phosphorylation and microtubule binding of tau protein stably transfected into Chinese hamster ovary cells. Mol. Biol. Cell. 6:1995;1397-1410.
40. Rothe M., Pan M.G., Henzel W.J., Ayres T.M., Goeddel D.V. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell. 83:1995;1243-1252.
41. Roy N., Deveraux Q.L., Takahashi R., Salvesen G.S., Reed J.C. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 16:1997;6914-6925.
42. Salvesen G.S., Duckett C.S. IAP proteins blocking the road to death's door . Nat. Rev. Mol. Cell Biol. 3:2002;401-410.
43. Seidl R., Bajo M., Bohm K., LaCasse E.C., MacKenzie A.E., Cairns N., Lubec G. Neuronal apoptosis inhibitory protein (NAIP)-like immunoreactivity in brains of adult patients with Down syndrome. J. Neural Transm. Suppl. 57:1999;283-291.
44. Shankar S.L., Mani S., O'Guin K.N., Kandimalla E.R., Agrawal S., Shafit-Zagardo B. Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways. J. Neurochem. 79:2001;426-436.
45. Silke J., Ekert P.G., Day C.L., Hawkins C.J., Baca M., Chew J., Pakusch M., Verhagen A.M., Vaux D.L. Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP. EMBO J. 20:2001;3114-3123.
46. Silke J., Hawkins C.J., Ekert P.G., Chew J., Day C.L., Pakusch M., Verhagen A.M., Vaux D.L. The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites. J. Cell Biol. 157:2002;115-124.
47. Simons M., Beinroth S., Gleichmann M., Liston P., Korneluk R.G., MacKenzie A.E., Bahr M., Klockgether T., Robertson G.S., Weller M., Schulz J.B. Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons. J. Neurochem. 72:1999;292-301.
48. Skoufias D.A., Mollinari C., Lacroix F.B., Margolis R.L. Human survivin is a kinetochore-associated passenger protein. J. Cell Biol. 151:2000;1575-1582.
49. Spillantini M.G., Van Swieten J.C., Goedert M. Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). NeuroGenetics. 2:2000;193-205.
50. Wilson R., Goyal L., Ditzel M., Zachariou A., Baker D.A., Agapite J., Steller H., Meier P. The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis. Natl. Cell Biol. 4:2002;445-450.
51. Xu D.G., Crocker S.J., Doucet J.P., St Jean M., Tamai K., Hakim A.M., Ikeda J.E., Liston P., Thompson C.S., Korneluk R.G., MacKenzie A., Robertson G.S. Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus. Nat. Med. 3:1997;997-1004.
52. Yen S., Easson C., Nacharaju P., Hutton M., Yen S.H. FTDP-17 tau mutations decrease the susceptibility of tau to calpain I digestion. FEBS Lett. 461:1999;91-95.