메뉴 건너뛰기




Volumn 4, Issue 9, 2001, Pages 1031-1042

Where are the new therapies for anxiety and obsessive-compulsive disorders?

Author keywords

[No Author keywords available]

Indexed keywords


EID: 0142176196     PISSN: 13697056     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (2)

References (154)
  • 1
    • 0029757677 scopus 로고    scopus 로고
    • Epidemiology and psychopharmacology of anxiety in medical patients
    • Stoudemire A: Epidemiology and psychopharmacology of anxiety in medical patients. J Clin Psychiatry (1996) 57:64-72.
    • (1996) J Clin Psychiatry , vol.57 , pp. 64-72
    • Stoudemire, A.1
  • 3
    • 0031937516 scopus 로고    scopus 로고
    • Generalised anxiety disorder Guidelines for diagnosis and treatment
    • Hoehn-Saric R: Generalised anxiety disorder: Guidelines for diagnosis and treatment. CNS Drugs (1998) 9:85-98.
    • (1998) CNS Drugs , vol.9 , pp. 85-98
    • Hoehn-Saric, R.1
  • 4
    • 33747030305 scopus 로고
    • Physical treatment of anxiety: The benzodiazepines
    • Roth M, Noyes R, Burrows GD (Eds), Elsevier Science Publishers, Amsterdam
    • Norman TR, Judd FK, Marriott PF, Burrows GD: Physical treatment of anxiety: the benzodiazepines. In: Handbook of anxiety, Roth M, Noyes R, Burrows GD (Eds), Elsevier Science Publishers, Amsterdam (1988)335-385.
    • (1988) Handbook of Anxiety , pp. 335-385
    • Norman, T.R.1    Judd, F.K.2    Marriott, P.F.3    Burrows, G.D.4
  • 5
    • 0029022179 scopus 로고
    • Current status of treatment with benzodiazepines
    • Laux G: Current status of treatment with benzodiazepines. Nervenarzt (1995) 66:311 -322.
    • (1995) Nervenarzt , vol.66 , pp. 311-322
    • Laux, G.1
  • 6
    • 0025784842 scopus 로고
    • The first double-blind, placebo-controlled trial of a partial benzodiazepine agonist abecarnil (ZK-112-119) in generalized anxiety disorder
    • Ballenger JC, Mcdonald S, Noyes R, Rickets K, Sussman N, Woods S, Patin J, Singer J: The first double-blind, placebo-controlled trial of a partial benzodiazepine agonist abecarnil (ZK-112-119) in generalized anxiety disorder. Psychopharmacol Bull (1991) 27:171179.
    • (1991) Psychopharmacol Bull , vol.27 , pp. 171179
    • Ballenger, J.C.1    Mcdonald, S.2    Noyes, R.3    Rickets, K.4    Sussman, N.5    Woods, S.6    Patin, J.7    Singer, J.8
  • 7
    • 0030726031 scopus 로고    scopus 로고
    • A double-blind evaluation of the safety and efficacy of abecarnil, alprazolam, and placebo in outpatients with generalized anxiety disorder
    • Lydiard RB, Ballenger JC, Rickels K: A double-blind evaluation of the safety and efficacy of abecarnil, alprazolam, and placebo in outpatients with generalized anxiety disorder. Abecarnil Work Group. J Clin Psychiatry (1997) 58(Suppl 11 ):11 -18.
    • (1997) Abecarnil Work Group. J Clin Psychiatry , vol.58 , Issue.11 SUPPL. , pp. 11-18
    • Lydiard, R.B.1    Ballenger, J.C.2    Rickels, K.3
  • 8
    • 0030715603 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled trial of two doses of abecarnil for geriatric anxiety
    • (Suppl11)
    • Small GW, Bystritsky A: Double-blind, placebo-controlled trial of two doses of abecarnil for geriatric anxiety. J Clin Psychiatry (1997) 58(Suppl11):24-9.
    • (1997) J Clin Psychiatry , vol.58 , pp. 24-29
    • Small, G.W.1    Bystritsky, A.2
  • 9
    • 33747027603 scopus 로고    scopus 로고
    • Anxiety/depression
    • Neurogen Corporation. Anxiety/depression. Company Website (2001) http://www.neurogen.com/pipeline/anxiety.htm
    • (2001) Company Website
  • 10
    • 0023753553 scopus 로고
    • Differential effects of alprazolam and imipramine in generalized anxiety disorder: Somatic versus psychic symptoms
    • Hoehn-Saric R, McLeod DR, Zmmerii WD: Differential effects of alprazolam and imipramine in generalized anxiety disorder: somatic versus psychic symptoms. J Clin Psychiatry (1988) 49:293301.
    • (1988) J Clin Psychiatry , vol.49 , pp. 293301
    • Hoehn-Saric, R.1    McLeod, D.R.2    Zmmerii, W.D.3
  • 12
    • 0033697738 scopus 로고    scopus 로고
    • Therapeutic effects of imipramine are counteracted by its metabolite, desipramine, in patients with generalized anxiety disorder
    • McLeod DR, Hoehn-Saric R, Porges SW, Kowalski PA, Clark CM: Therapeutic effects of imipramine are counteracted by its metabolite, desipramine, in patients with generalized anxiety disorder. J Clin Psychopharmacol (2000) 20:615-21.
    • (2000) J Clin Psychopharmacol , vol.20 , pp. 615-621
    • McLeod, D.R.1    Hoehn-Saric, R.2    Porges, S.W.3    Kowalski, P.A.4    Clark, C.M.5
  • 13
    • 0025296823 scopus 로고
    • The clinical course and long-term management of generalized anxiety disorder
    • Rickels K, Schweizer E: The clinical course and long-term management of generalized anxiety disorder. J Clin Psychopharmacol (1990) 10:101S-110S.
    • (1990) J Clin Psychopharmacol , vol.10
    • Rickels, K.1    Schweizer, E.2
  • 14
    • 0033758289 scopus 로고    scopus 로고
    • Efficacy, safety, and toterabilfty of venlafaxine XR in generalized anxiety disorder
    • Kelsey JE: Efficacy, safety, and toterabilfty of venlafaxine XR in generalized anxiety disorder. Depress Anxiety (2000) 12(Suppl 1):81-4.
    • (2000) Depress Anxiety , vol.12 , Issue.1 SUPPL. , pp. 81-84
    • Kelsey, J.E.1
  • 15
    • 0034697886 scopus 로고    scopus 로고
    • Efficacy of venlafaxine extended-release capsules in nondepressed outpatients with generalized anxiety disorder - A 6month randomized controlled trial
    • • This study is the first placebo-controlled demonstration of the long-term efficacy, rapid action, safety and once-daily administration of venlafaxine in GAD.
    • Gelenberg AJ, Lydiard RB, Rudolph RL, Aguiar L, Haskins JT, Salinas E: Efficacy of venlafaxine extended-release capsules in nondepressed outpatients with generalized anxiety disorder - A 6month randomized controlled trial. J Am Mod Assoc (2000) 283:3082-3088. • This study is the first placebo-controlled demonstration of the long-term efficacy, rapid action, safety and once-daily administration of venlafaxine in GAD.
    • (2000) J Am Mod Assoc , vol.283 , pp. 3082-3088
    • Gelenberg, A.J.1    Lydiard, R.B.2    Rudolph, R.L.3    Aguiar, L.4    Haskins, J.T.5    Salinas, E.6
  • 16
    • 0033378891 scopus 로고    scopus 로고
    • Overview of antidepressants currently used to treat anxiety disorders
    • • This comprehensive review shows that TCAs are effective across the anxiety disorders, while SSRIs are useful in panic disorder and OCD. TCAs cause serious adverse events, and SSRIs are slow to act and their efficacy is limited in GAD. Newer antidepressants, mirtazapine, nefazodone and venlafaxine XR are effective with good safety and tolerabllity.
    • Feighner JP: Overview of antidepressants currently used to treat anxiety disorders. J Clin Psychiatry (1999) 60(Suppl 22):18-22. • This comprehensive review shows that TCAs are effective across the anxiety disorders, while SSRIs are useful in panic disorder and OCD. TCAs cause serious adverse events, and SSRIs are slow to act and their efficacy is limited in GAD. Newer antidepressants, mirtazapine, nefazodone and venlafaxine XR are effective with good safety and tolerabllity.
    • (1999) J Clin Psychiatry , vol.60 , Issue.22 SUPPL.
    • Feighner, J.P.1
  • 17
    • 0028169944 scopus 로고
    • Neuropharmacology of 5hydroxytryptamine1B/D receptor ligands
    • Chopin P, Moret C, Briley M: Neuropharmacology of 5hydroxytryptamine1B/D receptor ligands. Pharmacol Trier (1994) 62:385-405.
    • (1994) Pharmacol Trier , vol.62 , pp. 385-405
    • Chopin, P.1    Moret, C.2    Briley, M.3
  • 19
    • 0029783673 scopus 로고    scopus 로고
    • Serotonin receptor specificity in anxiety disorders
    • Lucki l: Serotonin receptor specificity in anxiety disorders. J Clin Psychiatry (1996) 57(Suppl 6):5-10.
    • (1996) J Clin Psychiatry , vol.57 , Issue.6 SUPPL. , pp. 5-10
    • Lucki, L.1
  • 20
    • 0030788565 scopus 로고    scopus 로고
    • Mixed depression and anxiety serotoninIA receptors as a common pharmacologie ink
    • Stahl SM: Mixed depression and anxiety: serotoninIA receptors as a common pharmacologie ink. JClin Psychiatry (1997) 56(Suppl 8)20-6.
    • (1997) JClin Psychiatry , vol.56 , Issue.SUPPL. 8 , pp. 20-26
    • Stahl, S.M.1
  • 24
    • 0032970989 scopus 로고    scopus 로고
    • A review of central 5-HT receptors and their function
    • Bames NM, Sharp T: A review of central 5-HT receptors and their function. Neuropharmacology (1999) 38:1083-1152.
    • (1999) Neuropharmacology , vol.38 , pp. 1083-1152
    • Bames, N.M.1    Sharp, T.2
  • 25
    • 0028287265 scopus 로고
    • Current advances and trends in the treatment of depression
    • Blier P, de Montigny C: Current advances and trends in the treatment of depression. Trends Pharmacol Sei (1994) 15:220-226.
    • (1994) Trends Pharmacol Sei , vol.15 , pp. 220-226
    • Blier, P.1    De Montigny, C.2
  • 28
    • 0028972481 scopus 로고
    • Characterization of 5-hydroxytryptamine 1A properties of flesinoxan: In vivo electrophysiology and hypothermia study
    • Hadrav V, Blier P, Dennis T, Ortemann C, de Montigny C: Characterization of 5-hydroxytryptamine 1A properties of flesinoxan: in vivo electrophysiology and hypothermia study. Neuropharmacology (1995) 34:1311 -1326.
    • (1995) Neuropharmacology , vol.34 , pp. 1311-1326
    • Hadrav, V.1    Blier, P.2    Dennis, T.3    Ortemann, C.4    De Montigny, C.5
  • 30
    • 0005399675 scopus 로고
    • Double-blind, placebo controlled fixed dose study of flesinoxan in generalized anxiety disorder
    • Bradford LD, Stevens G: Double-blind, placebo controlled fixed dose study of flesinoxan in generalized anxiety disorder. Am Coll Neuropsychopharmacol (1994) 167.
    • (1994) Am Coll Neuropsychopharmacol , pp. 167
    • Bradford, L.D.1    Stevens, G.2
  • 32
    • 0031902593 scopus 로고    scopus 로고
    • New treatments for panic
    • Ballenger JC: New treatments for panic. Eur Psychiatry (1998) 13:753-81 S.
    • (1998) Eur Psychiatry , vol.13
    • Ballenger, J.C.1
  • 34
    • 0031464344 scopus 로고    scopus 로고
    • Moclobemide for anxiety disorders: A focus on moclobemide for panic disorder
    • Tiller JW, Bouwer C, Behnke K: Moclobemide for anxiety disorders: a focus on moclobemide for panic disorder. Int Clin Psychopharmacol (1997)12(Suppl6):S27-30.
    • (1997) Int Clin Psychopharmacol , vol.12 , Issue.SUPPL. 6
    • Tiller, J.W.1    Bouwer, C.2    Behnke, K.3
  • 36
    • 0027452146 scopus 로고
    • Reversible monoamine oxidase-A inhibitors in panic disorder
    • (Suppl2):S77-82.
    • Bakish D, Saxena BM, Bowen R, D'Souza J: Reversible monoamine oxidase-A inhibitors in panic disorder. Clin Neuropharmacol (1993) 16(Suppl2):S77-82.
    • (1993) Clin Neuropharmacol , vol.16
    • Bakish, D.1    Saxena, B.M.2    Bowen, R.3    D'Souza, J.4
  • 37
    • 0027358532 scopus 로고
    • MAO inhibitors in panic disorder: Clinical effects of treatment with brofaromine: A double Wind placebo controlled study
    • Van VCet IM, Westenberg HGM, Den Boer JA: MAO inhibitors in panic disorder: Clinical effects of treatment with brofaromine: A double Wind placebo controlled study. Psychopharmacology (1993) 112:483-489.
    • (1993) Psychopharmacology , vol.112 , pp. 483-489
    • Van Vcet, I.M.1    Hgm, W.2    Den Boer, J.A.3
  • 39
    • 0030946581 scopus 로고    scopus 로고
    • Behavioural profiles of the reversible monoamine-oxidase-A inhibitors befloxatone and moclobemide in an experimental model for screening anxiolytic and anti-panic drugs
    • Griebel G, Perrault G, Sanger DJ: Behavioural profiles of the reversible monoamine-oxidase-A inhibitors befloxatone and moclobemide in an experimental model for screening anxiolytic and anti-panic drugs. Psychopharmacology (1997) 131:180-186.
    • (1997) Psychopharmacology , vol.131 , pp. 180-186
    • Griebel, G.1    Perrault, G.2    Sanger, D.J.3
  • 40
    • 0033825750 scopus 로고    scopus 로고
    • The side effects burden of extended imipramine treatment of panic disorder
    • Mavissakalian MB, Perel JM: The side effects burden of extended imipramine treatment of panic disorder. J Clin Psychopharmacol (2000) 20:547-555.
    • (2000) J Clin Psychopharmacol , vol.20 , pp. 547-555
    • Mavissakalian, M.B.1    Perel, J.M.2
  • 42
    • 0030988949 scopus 로고    scopus 로고
    • Antidepressants in panic disorder
    • 58(Suppl2)20-24.
    • Jefferson JW: Antidepressants in panic disorder. J Clin Psychiatry (1997)58(Suppl2):20-24.
    • (1997) J Clin Psychiatry
    • Jefferson, J.W.1
  • 45
    • 33746936511 scopus 로고    scopus 로고
    • Selective serotonin-reuptake inhibitors in anxiety disorders: Room for improvement
    • • A recent and complete review of SSRIs in anxiety disorders such as GAD, panic disorder, social phobia, PTSD and OCD.
    • Baldwin DS, Birtwistle J: Selective serotonin-reuptake inhibitors in anxiety disorders: room for improvement. In: Anxiolytics, Briley M & Nutt D (Eds), Birkhäuser Verlag, Basel (2000) 55-75. • A recent and complete review of SSRIs in anxiety disorders such as GAD, panic disorder, social phobia, PTSD and OCD.
    • (2000) Anxiolytics, Briley M & Nutt D (Eds), Birkhäuser Verlag, Basel , pp. 55-75
    • Baldwin, D.S.1    Birtwistle, J.2
  • 47
    • 0031984862 scopus 로고    scopus 로고
    • Doubleblind, fixed-dose, placebo-controlled study of paroxetine in the treatment of panic disorder
    • Ballenger JC, Wheadon DE, Steiner M, Bushnell W, Gergel IP: Doubleblind, fixed-dose, placebo-controlled study of paroxetine in the treatment of panic disorder. Am J Psychiatry (1998) 155:36-42.
    • (1998) Am J Psychiatry , vol.155 , pp. 36-42
    • Ballenger, J.C.1    Wheadon, D.E.2    Steiner, M.3    Bushnell, W.4    Gergel, I.P.5
  • 48
    • 0031904155 scopus 로고    scopus 로고
    • Pharmacotherapy of panic disorder: Differential efficacy from a clinical viewpoint
    • den Boer JA: Pharmacotherapy of panic disorder: differential efficacy from a clinical viewpoint. J Clin Psychiatry (1998) 59(Suppl 8):30-36.
    • (1998) J Clin Psychiatry , vol.59 , Issue.SUPPL. 8 , pp. 30-36
    • Boer, J.A.1
  • 50
    • 0024412584 scopus 로고
    • Chotecystokinin tetrapeptide induces panic-tike attacks in healthy volunteers
    • de Montigny C: Chotecystokinin tetrapeptide induces panic-tike attacks in healthy volunteers. Arch Gen Psychiatry(1989) 46:511-517.
    • (1989) Arch Gen Psychiatry , vol.46 , pp. 511-517
    • Montigny, C.1
  • 51
    • 0030220613 scopus 로고    scopus 로고
    • The panicinducing properties of the cholecystokinin tetrapeptide CCK4 in patients with panic disorder
    • van Megen HJ, Westenberg HG, Den Boer JA, Kahn RS: The panicinducing properties of the cholecystokinin tetrapeptide CCK4 in patients with panic disorder. Eur Neuropsychopharmacol (1996) 6:187-94.
    • (1996) Eur Neuropsychopharmacol , vol.6 , pp. 187-194
    • Megen, H.J.1    Westenberg, H.G.2    Den Boer, J.A.3    Kahn, R.S.4
  • 54
    • 0028237882 scopus 로고
    • The panicogenic effects of cholecystokinintetrapeptide are antagonized by L-365,260, a central cholecystokinin receptor antagonist, in patients with panic disorder
    • Bradwejn J, Koszycki D, Couetoux du Tertre A, van Megen H, den Boer J, Westenberg H: The panicogenic effects of cholecystokinintetrapeptide are antagonized by L-365,260, a central cholecystokinin receptor antagonist, in patients with panic disorder. Arch Gen Psychiatry (1994) 51:486-93.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 486-493
    • Bradwejn, J.1    Koszycki, D.2    Couetoux Du Tertre, A.3    Van Megen, H.4    Den Boer, J.5    Westenberg, H.6
  • 55
    • 0028962236 scopus 로고
    • Cholecystokinin and anxiety in normal volunteers: An investigation of the anxiogenic properties of pentagastrin and reversal by the cholecystokinin receptor subtype B antagonist L-365,260
    • Lines C, Challenor J, Traub M: Cholecystokinin and anxiety in normal volunteers: An investigation of the anxiogenic properties of pentagastrin and reversal by the cholecystokinin receptor subtype B antagonist L-365,260. Br J Clin Pharmacol (1995) 39:235-242.
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 235-242
    • Lines, C.1    Challenor, J.2    Traub, M.3
  • 56
    • 0028825033 scopus 로고
    • Effect of CI-988 on cholecystokinin tetrapeptide-induced panic symptoms in healthy volunteers
    • Bradwejn J, Koszycki D, Paradis M, Reece P, Hinton J, Sedman A: Effect of CI-988 on cholecystokinin tetrapeptide-induced panic symptoms in healthy volunteers. Blot Psychiatry (1995) 38:742-746.
    • (1995) Blot Psychiatry , vol.38 , pp. 742-746
    • Bradwejn, J.1    Koszycki, D.2    Paradis, M.3    Reece, P.4    Hinton, J.5    Sedman, A.6
  • 58
    • 14444288026 scopus 로고    scopus 로고
    • (3R)-M(1-(tertbutylcarbonylmethyl)-2>dihydro-2-oxo-5-(2-pyridyr)-1/f 1,4benzodiazepin-3-yi)-Ar methylaminophenylXrea (YF476): A potent and oraBy active gastrin/CCK-B antagonist
    • Semple G, Ryder H, Rooker DP, Batt AR, Kendrick DA, Szelke M, Ohta M, Satoh M, Nishkla A, Akuzawa S, Miyata K: (3R)-M(1-(tertbutylcarbonylmethyl)-2>dihydro-2-oxo-5-(2-pyridyr)-1/f 1,4benzodiazepin-3-yi)-Ar methylamino)phenylXrea (YF476): a potent and oraBy active gastrin/CCK-B antagonist J Med Chem (1997) 40:331341.
    • (1997) J Med Chem , vol.40 , pp. 331341
    • Semple, G.1    Ryder, H.2    Rooker, D.P.3    Batt, A.R.4    Kendrick, D.A.5    Szelke, M.6    Ohta, M.7    Satoh, M.8    Nishkla, A.9    Akuzawa, S.10    Miyata, K.11
  • 59
    • 0030175369 scopus 로고    scopus 로고
    • Targeted' molecular diversity: Design and development of non-peptide antagonists for chotecystokinin and tachykinin receptors
    • Horwell D, Pritchard M, Raphy J, Ratcliffe G: 'Targeted' molecular diversity: design and development of non-peptide antagonists for chotecystokinin and tachykinin receptors. Immunopharmaco/ogy (1996)33:68-72.
    • (1996) Immunopharmaco/ogy , vol.33 , pp. 68-72
    • Horwell, D.1    Pritchard, M.2    Raphy, J.3    Ratcliffe, G.4
  • 61
    • 0027484197 scopus 로고
    • The Zurich study. XX. Social phobia and agoraphobia
    • Degonda M, Angst J: The Zurich study. XX. Social phobia and agoraphobia. EurArch Psychiatry Clin Weurosc/(1993) 243:95-102.
    • (1993) EurArch Psychiatry Clin Weurosc , vol.243 , pp. 95-102
    • Degonda, M.1    Angst, J.2
  • 65
    • 0025761832 scopus 로고
    • Imipramine an effective treatment for illness phobia
    • Wesner RB, Noyes R Jr. Imipramine an effective treatment for illness phobia. J Affect Disord (1991) 22:4348.
    • (1991) J Affect Disord , vol.22 , pp. 4348
    • Wesner, R.B.1    Noyes Jr., R.2
  • 67
    • 0033772519 scopus 로고    scopus 로고
    • Drugs in development for social anxiety disorder: More to social anxiety than meets the SSRI
    • • A recent review on drugs in development for social phobia including current options, such as SSRIs, and new and promising directions such as substance P antagonists, GABA agonists and CRF antagonists.
    • Ameringen MV, Mancini C, Farvolden P, Oakman J: Drugs in development for social anxiety disorder: more to social anxiety than meets the SSRI. Exp Opin Invest Drugs (2000) 9:2215-2231. • A recent review on drugs in development for social phobia including current options, such as SSRIs, and new and promising directions such as substance P antagonists, GABA agonists and CRF antagonists.
    • (2000) Exp Opin Invest Drugs , vol.9 , pp. 2215-2231
    • Ameringen, M.V.1    Mancini, C.2    Farvolden, P.3    Oakman, J.4
  • 68
    • 0028340187 scopus 로고
    • Psychopharmacological treatment of social phobia; a double blind placebo controlled study with fluvoxamine
    • van Vliet IM, den Boer JA, Westenberg HG: Psychopharmacological treatment of social phobia; a double blind placebo controlled study with fluvoxamine. Psychopharmacology (1994) 115:128-134.
    • (1994) Psychopharmacology , vol.115 , pp. 128-134
    • Vliet, I.M.1    Den Boer, J.A.2    Westenberg, H.G.3
  • 69
    • 0032894805 scopus 로고    scopus 로고
    • Fluvoxamine treatment of social phobia (social anxiety disorder): A doubleblind, placebo-controlled study
    • Stein MB, Fyer AJ, Davidson JRT, Pollack MH, Wiita B: Fluvoxamine treatment of social phobia (social anxiety disorder): A doubleblind, placebo-controlled study. Am J Psychiatry (1999) 156:756-760.
    • (1999) Am J Psychiatry , vol.156 , pp. 756-760
    • Stein, M.B.1    Fyer, A.J.2    Davidson, J.R.T.3    Pollack, M.H.4    Wiita, B.5
  • 70
    • 0032569245 scopus 로고    scopus 로고
    • Paroxetine treatment of generalized social phobia (social anxiety disorder): A randomized controlled trial
    • Stein MB, LJebowitz MR, Lydiard RB, Pitts CD, Bushnell W, Gergel I: Paroxetine treatment of generalized social phobia (social anxiety disorder): a randomized controlled trial. J Am Med Assoc (1998) 280:708-713.
    • (1998) J Am Med Assoc , vol.280 , pp. 708-713
    • Stein, M.B.1    Ljebowitz, M.R.2    Lydiard, R.B.3    Pitts, C.D.4    Bushnell, W.5    Gergel, I.6
  • 72
    • 0030014796 scopus 로고    scopus 로고
    • Paroxetine in the treatment of generalized social phobia: Openlabel treatment and double-blind placebo-controlled discontinuation
    • Stein MB, Charter MJ, Hazen AL, Kroft CDL, Châle RA, Coté D, Walker JR: Paroxetine in the treatment of generalized social phobia: Openlabel treatment and double-blind placebo-controlled discontinuation. J Clin Psychopharmacol (1996) 16:218-222.
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 218-222
    • Stein, M.B.1    Charter, M.J.2    Hazen, A.L.3    Kroft, C.D.L.4    Châle, R.A.5    Coté, D.6    Walker, J.R.7
  • 76
    • 0026523814 scopus 로고
    • Drug therapy of post-traumatic stress disorder
    • Davidson J: Drug therapy of post-traumatic stress disorder. Br J Psychiatry (1992) 160:309-314.
    • (1992) Br J Psychiatry , vol.160 , pp. 309-314
    • Davidson, J.1
  • 77
    • 0034016473 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors in post-traumatic stress disorder
    • • A recent review of SSRIs as first-line therapy, alleviating the core symptoms of PTSD, and being effective for the treatment of comorbid disorders such as depression, panic disorder and social phobia
    • Hidalgo RB, Davidson JR: Selective serotonin reuptake inhibitors in post-traumatic stress disorder. J Psychopharmacol (2000) 14:70-76. • A recent review of SSRIs as first-line therapy, alleviating the core symptoms of PTSD, and being effective for the treatment of comorbid disorders such as depression, panic disorder and social phobia." '
    • (2000) J Psychopharmacol , vol.14 , pp. 70-76
    • Hidalgo, R.B.1    Davidson, J.R.2
  • 80
    • 0031426430 scopus 로고    scopus 로고
    • Response characteristics to antidepressants and placebo in post-traumatic stress disorder
    • Davidson JR, Malik ML, Sutherland SN: Response characteristics to antidepressants and placebo in post-traumatic stress disorder. In! Clin Psychopharmacol(1997) 12:291-296.
    • (1997) In! Clin Psychopharmacol , vol.12 , pp. 291-296
    • Davidson, J.R.1    Malik, M.L.2    Sutherland, S.N.3
  • 81
    • 0032402583 scopus 로고    scopus 로고
    • Treatment of severe, drug resistant obsessive compulsive disorder with the 5HT1D agonist sumatriptan
    • Stem L, Zohar J,-Cohen R, Sasson Y: Treatment of severe, drug resistant obsessive compulsive disorder with the 5HT1D agonist sumatriptan. Eur Neuropsychopharmacol (1998) 8:325-328.
    • (1998) Eur Neuropsychopharmacol , vol.8 , pp. 325-328
    • Stem, L.1    Zohar, J.2    Cohen, R.3    Sasson, Y.4
  • 82
    • 0030892507 scopus 로고    scopus 로고
    • Pharmacotherapy of obsessive compulsive disorder
    • Pigott TA, Seay S: Pharmacotherapy of obsessive compulsive disorder. Int Rev Psychiatry (1997) 9:133-147.
    • (1997) Int Rev Psychiatry , vol.9 , pp. 133-147
    • Pigott, T.A.1    Seay, S.2
  • 83
    • 0028800848 scopus 로고
    • Efficacy and tolerability of serotonin transport inhibitors in obsessivecompulsive disorder: A meta-analysis
    • Greist JH, Jefferson JW, Kobak KA, Katzelnick DJ, Serlin RC: Efficacy and tolerability of serotonin transport inhibitors in obsessivecompulsive disorder: A meta-analysis. Arch Gen Psychiatry (1995) 52:53-60.
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 53-60
    • Greist, J.H.1    Jefferson, J.W.2    Kobak, K.A.3    Katzelnick, D.J.4    Serlin, R.C.5
  • 84
    • 0025614688 scopus 로고
    • Milnacipran et trouble obsessionel-compulsH: Etude d'un cas
    • Papart P, Ansseau M: Milnacipran et trouble obsessionel-compulsH: Etude d'un cas. Psychiatr Psychobiol (1990) 5:325-327.
    • (1990) Psychiatr Psychobiol , vol.5 , pp. 325-327
    • Papart, P.1    Ansseau, M.2
  • 85
    • 0023233004 scopus 로고
    • Drug treatment of obsessive-compulsive disorder
    • Zohar J, Insel TR: Drug treatment of obsessive-compulsive disorder. J Affect Disord (1987) 13:193-202.
    • (1987) J Affect Disord , vol.13 , pp. 193-202
    • Zohar, J.1    Insel, T.R.2
  • 86
    • 0034666574 scopus 로고    scopus 로고
    • The possible role of 5-HT, receptors in psychiatric disorders and their potential as a target for therapy
    • Moret C, Briley M: The possible role of 5-HT, receptors in psychiatric disorders and their potential as a target for therapy. Eur JPharmacol(2000) 404:1-12.
    • (2000) Eur JPharmacol , vol.404 , pp. 1-12
    • Moret, C.1    Briley, M.2
  • 89
    • 0029877198 scopus 로고    scopus 로고
    • The pathogenesis and treatment of obsessive-compulsive disorder
    • Dolberg OT, lancu I, Sasson Y, Zohar J: The pathogenesis and treatment of obsessive-compulsive disorder. Clin Neuropharmacol (1996)19:129-147.
    • (1996) Clin Neuropharmacol , vol.19 , pp. 129-147
    • Dolberg, O.T.1    Lancu, I.2    Sasson, Y.3    Zohar, J.4
  • 90
    • 0003099836 scopus 로고    scopus 로고
    • Is 5-HT10 involved in obsessive-compulsive disorder?
    • Zohar J: Is 5-HT10 involved in obsessive-compulsive disorder? Am Coll Neuropsychopharmacol (1996) 6:54-55.
    • (1996) Am Coll Neuropsychopharmacol , vol.6 , pp. 54-55
    • Zohar, J.1
  • 92
    • 0033180228 scopus 로고    scopus 로고
    • Single photon emission computed tomography of the brain with Tc-99m HMPAO during sumatriptan challenge in obsessive-compulsive disorder: Investigating the functional role of the serotonin auto-receptor
    • Stein DJ, Van Heerden B, Wessels CJ, Van Kradenburg J, Warwick J, Wasserman HJ: Single photon emission computed tomography of the brain with Tc-99m HMPAO during sumatriptan challenge in obsessive-compulsive disorder: investigating the functional role of the serotonin auto-receptor. Prog Neuropsychopharmacol Biol Psychiatry (1999) 23:1079-1099.
    • (1999) Prog Neuropsychopharmacol Biol Psychiatry , vol.23 , pp. 1079-1099
    • Stein, D.J.1    Van Heerden, B.2    Wessels, C.J.3    Van Kradenburg, J.4    Warwick, J.5    Wasserman, H.J.6
  • 93
    • 0025007068 scopus 로고
    • The GABA-A/benzodiazepine receptor implications for the molecular basis of anxiety
    • Breier A, Paul SM: The GABA-A/benzodiazepine receptor implications for the molecular basis of anxiety. J Psychiatr Res (1990)24:91-104.
    • (1990) J Psychiatr Res , vol.24 , pp. 91-104
    • Breier, A.1    Paul, S.M.2
  • 94
    • 0030445551 scopus 로고    scopus 로고
    • Further evidence for differences between non-selective and BZ-1 (omegal) selective, benzodiazepine receptor ligands in murine models of 'state' and 'trait' anxiety
    • Griebel G, Sanger DJ, Perrault G: Further evidence for differences between non-selective and BZ-1 (omegal) selective, benzodiazepine receptor ligands in murine models of 'state' and 'trait' anxiety. Neuropharmacology (1996) 35:1081-1091.
    • (1996) Neuropharmacology , vol.35 , pp. 1081-1091
    • Griebel, G.1    Sanger, D.J.2    Perrault, G.3
  • 95
    • 0026710490 scopus 로고
    • Differential development of tolerance to the depressant effects of benzodiazepine and non-benzodiazepine agonists at the omega (BZ) modulatory sites of GABAA receptors
    • Sanger DJ, Zivkovic B: Differential development of tolerance to the depressant effects of benzodiazepine and non-benzodiazepine agonists at the omega (BZ) modulatory sites of GABAA receptors. Neuropharmacology (1992) 31:693-700.
    • (1992) Neuropharmacology , vol.31 , pp. 693-700
    • Sanger, D.J.1    Zivkovic, B.2
  • 96
    • 0028176806 scopus 로고
    • Distribution of the serotonin 5-HT, receptor family mRNAs: Comparison between 5-HTu and 5HT,. receptors
    • Pompeiano M, Palacios JM, Mengod G: Distribution of the serotonin 5-HT, receptor family mRNAs: comparison between 5-HTu and 5HT,. receptors. Brain Res Mol Brain Res (1994) 23:163-178.
    • (1994) Brain Res Mol Brain Res , vol.23 , pp. 163-178
    • Pompeiano, M.1    Palacios, J.M.2    Mengod, G.3
  • 97
    • 0030612256 scopus 로고    scopus 로고
    • Distribution of the 5hydroxytryptamirte receptor protein in adult rat brain and spinal cord determined using a receptor-directed antibody: Effect of 5,7dihydroxytryptamine
    • Sharma A, Punhani T, Föne KG: Distribution of the 5hydroxytryptamirte receptor protein in adult rat brain and spinal cord determined using a receptor-directed antibody: Effect of 5,7dihydroxytryptamine. Synapse (1997) 27:45-56.
    • (1997) Synapse , vol.27 , pp. 45-56
    • Sharma, A.1    Punhani, T.2    Föne, K.G.3
  • 99
    • 4243417418 scopus 로고    scopus 로고
    • Brain 5-HT,. receptors: Potential role in anxiety disorders
    • Anxiolytics, Briley M & Nutt D (Eds), • A state of the art review showing that selective 5-HT2 receptor ligands generate interest by their innovation and therapeutic opportunities.
    • Jenck F, Moreau J-L, Wichmann J, Stadier H, Martin JR, Bös M: Brain 5-HT,. receptors: potential role in anxiety disorders. In: Anxiolytics, Briley M & Nutt D (Eds), Birkhäuser Verlag, Basel (2000) 119-137. • A state of the art review showing that selective 5-HT2 receptor ligands generate interest by their innovation and therapeutic opportunities.
    • (2000) Birkhäuser Verlag, Basel , pp. 119-137
    • Jenck, F.1    Moreau, J.-L.2    Wichmann, J.3    Stadier, H.4    Martin, J.R.5    Bös, M.6
  • 102
    • 0030958204 scopus 로고    scopus 로고
    • Synthesis, pharmacology and therapeutic potential of 10methoxypyrazino[1,2-a]indotes, partial agonists at the 5-HTK receptor
    • Bös M, Jenck F, Martin JR, Moreau J-L, Mutel V, Sleight A, Widmer U: Synthesis, pharmacology and therapeutic potential of 10methoxypyrazino[1,2-a]indotes, partial agonists at the 5-HTK receptor. EurJMedChem (1997) 32:253-261.
    • (1997) EurJMedChem , vol.32 , pp. 253-261
    • Bös, M.1    Jenck, F.2    Martin, J.R.3    Moreau, J.-L.4    Mutel, V.5    Sleight, A.6    Widmer, U.7
  • 104
    • 0031884405 scopus 로고    scopus 로고
    • Deramciclane, a putative anxiolytic drug, is a serotonin 5HTK receptor inverse agonist but fails to induce 5-HTK receptor down-regulation
    • Pàlvimaki EP, Majasuo H, Kuoppamaki M, Mannisto PT, Syvalahti E, HietaJa J: Deramciclane, a putative anxiolytic drug, is a serotonin 5HTK receptor inverse agonist but fails to induce 5-HTK receptor down-regulation. Psychopharmacology (1998) 136:99-104.
    • (1998) Psychopharmacology , vol.136 , pp. 99-104
    • Pàlvimaki, E.P.1    Majasuo, H.2    Kuoppamaki, M.3    Mannisto, P.T.4    Syvalahti, E.5    Hietaja, J.6
  • 108
    • 0025193091 scopus 로고
    • The effects of 5-HT,. characterizing agents in the mouse elevated plus-maze
    • Benjamin D, La! H, Meyerson LR: The effects of 5-HT,. characterizing agents in the mouse elevated plus-maze. Life Sc/(1990) 47:195-203.
    • (1990) Life Sc/ , vol.47 , pp. 195-203
    • Benjamin, D.1    La, H.2    Meyerson, L.R.3
  • 109
    • 0027056458 scopus 로고
    • Anxiogenic-like effects of fluprazine and eltoprazine in the mouse elevated plus-maze: Profile comparisons with 8-OH-DPAT, CGS 12066B,TFMPPand mCPP
    • Rodgers RJ, Cole JC, Cobain MR, Daly P, Doran PJ, Eells JR, Wallis P: Anxiogenic-like effects of fluprazine and eltoprazine in the mouse elevated plus-maze: profile comparisons with 8-OH-DPAT, CGS 12066B,TFMPPand mCPP. Behav Pharmacol (1992) 3:621-634.
    • (1992) Behav Pharmacol , vol.3 , pp. 621-634
    • Rodgers, R.J.1    Cole, J.C.2    Cobain, M.R.3    Daly, P.4    Doran, P.J.5    Eells, J.R.6    Wallis, P.7
  • 111
    • 0034063103 scopus 로고    scopus 로고
    • Distress vocalizations in maternally separated mouse pups: Modulation via 5-HT1A, 5-HT, and GABAA receptors
    • Fish EW, Sekinda M, Ferrari PF, Dirks A, Miczek KA: Distress vocalizations in maternally separated mouse pups: modulation via 5-HT1A, 5-HT, and GABAA receptors. Psychopharmacology (2000) 149:277-285.
    • (2000) Psychopharmacology , vol.149 , pp. 277-285
    • Fish, E.W.1    Sekinda, M.2    Ferrari, P.F.3    Dirks, A.4    Miczek, K.A.5
  • 112
    • 0342600479 scopus 로고    scopus 로고
    • Interactions between 5HT,B and benzodiazepine receptor ligands in the light/dark box anxiety model in mice
    • Chopin P, Colpaert FC, Moret C, Marien M: Interactions between 5HT,B and benzodiazepine receptor ligands in the light/dark box anxiety model in mice. Sec Neurosci Abs (1998) 24:601.
    • (1998) Sec Neurosci Abs , vol.24 , pp. 601
    • Chopin, P.1    Colpaert, F.C.2    Moret, C.3    Marien, M.4
  • 113
    • 0027389222 scopus 로고
    • Effect of diazepam on cortical 5-HT release and behaviour in the guinea-pig on exposure to the elevated plus maze
    • Rex A, Marsden CA, Fink H: Effect of diazepam on cortical 5-HT release and behaviour in the guinea-pig on exposure to the elevated plus maze. Psychopharmacology (1993) 110:490-496.
    • (1993) Psychopharmacology , vol.110 , pp. 490-496
    • Rex, A.1    Marsden, C.A.2    Fink, H.3
  • 114
    • 0029665410 scopus 로고    scopus 로고
    • 5-HT,D-like receptors inhibit the release of endogenously formed ['H]GABA in human, but not in rabbit, neocortex
    • Feuerstein TJ, Huring H, van Vefthoven V, Lucking CH, Landwehrmeyer GB: 5-HT,D-like receptors inhibit the release of endogenously formed ['H]GABA in human, but not in rabbit, neocortex. Neurosci Lett (1996) 209:210-214.
    • (1996) Neurosci Lett , vol.209 , pp. 210-214
    • Feuerstein, T.J.1    Huring, H.2    Van Vefthoven, V.3    Lucking, C.H.4    Landwehrmeyer, G.B.5
  • 115
    • 0343446115 scopus 로고    scopus 로고
    • An autoradiographic study of serotonergic receptors in a murine genetic model of anxietyrelated behaviors
    • Clément Y, Kia KH, Daval G, Vergé D: An autoradiographic study of serotonergic receptors in a murine genetic model of anxietyrelated behaviors. Brain Res (1996) 709:229-242.
    • (1996) Brain Res , vol.709 , pp. 229-242
    • Clément, Y.1    Kia, K.H.2    Daval, G.3    Vergé, D.4
  • 120
    • 0032778973 scopus 로고    scopus 로고
    • Anxiety, motor activation and maternal-infant interactions in 5-HT, knockout mice
    • Brunner D, Buhot MC, Hen R, Hofer M: Anxiety, motor activation and maternal-infant interactions in 5-HT, knockout mice. Behav Neurosci (1999) 113:587-601.
    • (1999) Behav Neurosci , vol.113 , pp. 587-601
    • Brunner, D.1    Buhot, M.C.2    Hen, R.3    Hofer, M.4
  • 121
    • 0032469106 scopus 로고    scopus 로고
    • The therapeutic potential of 5-HT, autoreceptors and heteroreceptors and 5-HT moduline in CNS disorders
    • • A useful summary of the potential of 5-HT moduline, an endogenous modulator of serotonin activity. Its biochemical and pharmacological properties are described and its potential role in psychiatric pathophysiologyparticularly anxiety-and its therapeutic implications are presented.
    • Sarhan H, Pillion G: The therapeutic potential of 5-HT, autoreceptors and heteroreceptors and 5-HT moduline in CNS disorders. CNS Spectrums (1998) 3:50-58. • A useful summary of the potential of 5-HT moduline, an endogenous modulator of serotonin activity. Its biochemical and pharmacological properties are described and its potential role in psychiatric pathophysiologyparticularly anxiety-and its therapeutic implications are presented.
    • (1998) CNS Spectrums , vol.3 , pp. 50-58
    • Sarhan, H.1    Pillion, G.2
  • 123
    • 0022271280 scopus 로고
    • Comparative distribution of cholecystokinin and other neuropeptides
    • Crawley JN: Comparative distribution of cholecystokinin and other neuropeptides. Ann WYMcadSc/(1985) 448:1-8.
    • (1985) Ann WYMcadSc/ , vol.448 , pp. 1-8
    • Crawley, J.N.1
  • 125
    • 0024412584 scopus 로고
    • Cholecystokinin tetrapeptide induces panic-like attacks in healthy volunteers
    • de Montigny C: Cholecystokinin tetrapeptide induces panic-like attacks in healthy volunteers. Preliminary findings. Arch Gen Psychiatry (1989) 46:511-517.
    • (1989) Preliminary Findings. Arch Gen Psychiatry , vol.46 , pp. 511-517
    • Montigny, C.1
  • 126
    • 0029593616 scopus 로고
    • Corticotropin-releasing factor receptors: Physiology, pharmacology, biochemistry and role in central nervous system and immune disorders
    • De Souza EB: Corticotropin-releasing factor receptors: physiology, pharmacology, biochemistry and role in central nervous system and immune disorders. Psychoneuroendocrinology (1995) 20:789-819.
    • (1995) Psychoneuroendocrinology , vol.20 , pp. 789-819
    • De Souza, E.B.1
  • 129
    • 0027450169 scopus 로고
    • Modulation of anxiety and neuropeptide ' Y-Y, receptors by antisense oligodeoxynucleotides
    • Wahlestedt C, Pich EM, Koob GF, Yee F, Heilig M: Modulation of anxiety and neuropeptide ' Y-Y, receptors by antisense oligodeoxynucleotides. Science (1993) 259:528-531.
    • (1993) Science , vol.259 , pp. 528-531
    • Wahlestedt, C.1    Pich, E.M.2    Koob, G.F.3    Yee, F.4    Heilig, M.5
  • 132
    • 0023943178 scopus 로고
    • Neuropeptide Y and peptide YY as possible cerebrospinal fluid markers for major depression and schizophrenia
    • Widerlov E, Lindstrom LH, Wahlestedt C, Ekman R: Neuropeptide Y and peptide YY as possible cerebrospinal fluid markers for major depression and schizophrenia. J Psychiatry Res (1988) 22:69-79.
    • (1988) J Psychiatry Res , vol.22 , pp. 69-79
    • Widerlov, E.1    Lindstrom, L.H.2    Wahlestedt, C.3    Ekman, R.4
  • 135
  • 137
    • 0027818746 scopus 로고
    • Distinct spatiotemporal distributions of the NMDA receptor channel subunH mRNAs in the brain
    • Watanabe M, Inoue Y, Sakimura K, Mishina M: Distinct spatiotemporal distributions of the NMDA receptor channel subunH mRNAs in the brain. Ann NYAcadSci (1993) 707:463-466.
    • (1993) Ann NYAcadSci , vol.707 , pp. 463-466
    • Watanabe, M.1    Inoue, Y.2    Sakimura, K.3    Mishina, M.4
  • 138
    • 0028343648 scopus 로고
    • Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
    • Monyer H, Bumashev N, Laune DJ, Sakmann B, Seeburg PH: Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron (1994) 12:529-540.
    • (1994) Neuron , vol.12 , pp. 529-540
    • Monyer, H.1    Bumashev, N.2    Laune, D.J.3    Sakmann, B.4    Seeburg, P.H.5
  • 139
    • 0031751159 scopus 로고    scopus 로고
    • Chronic administration of imipramine and chalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain - A quantitative in situ hybridization study
    • Boyer PA, Skolnick P, Fossom LH: Chronic administration of imipramine and chalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain - A quantitative in situ hybridization study. J Mol Neurosci (1998) 10:219-233.
    • (1998) J Mol Neurosci , vol.10 , pp. 219-233
    • Boyer, P.A.1    Skolnick, P.2    Fossom, L.H.3
  • 141
    • 0028340993 scopus 로고
    • Sensitivity of the N-methyl-D-aspartate receptor to poryamines is controlled by NR2 subunits
    • Williams K, Zappia AM, Pritchett DB, Shen YM, Molinoff PB: Sensitivity of the N-methyl-D-aspartate receptor to poryamines is controlled by NR2 subunits. Mo!Pharmacol (1994) 45:803-809.
    • (1994) Mo!Pharmacol , vol.45 , pp. 803-809
    • Williams, K.1    Zappia, A.M.2    Pritchett, D.B.3    Shen, Y.M.4    Molinoff, P.B.5
  • 142
    • 84889851956 scopus 로고    scopus 로고
    • Glutamate receptor ligands
    • • A review of the subject which presents NMDA receptor biology and, with preclinical studies, the anxiogenic activation of NMDA receptors and the potential anxiolytic actions of NMDA receptor antagonists or Group II metabotropic glutamate receptor agonists.
    • Skolnick P: Glutamate receptor ligands. In: Anxiolytics, Briley M & Nutt D (Eds), Birkhäuser Vertag, Basel (2000) 139-150. • A review of the subject which presents NMDA receptor biology and, with preclinical studies, the anxiogenic activation of NMDA receptors and the potential anxiolytic actions of NMDA receptor antagonists or Group II metabotropic glutamate receptor agonists.
    • (2000) Anxiolytics, Briley M & Nutt D (Eds), Birkhäuser Vertag, Basel , pp. 139-150
    • Skolnick, P.1
  • 143
    • 0003978396 scopus 로고
    • Anxiolytic actions of competitive Nmethyl-D-aspartate receptor antagonist A comparison with benzodiazepine modulators and dissociate anesthetics
    • Cavalheiro E, Lehmann J, Turski L (Eds), Alan LJss, New York
    • LJebman JM, Bennett DA: Anxiolytic actions of competitive Nmethyl-D-aspartate receptor antagonist: A comparison with benzodiazepine modulators and dissociate anesthetics. In: Frontiers in excitatory ammo acid research, Cavalheiro E, Lehmann J, Turski L (Eds), Alan LJss, New York (1988) 301-308.
    • (1988) Frontiers in Excitatory Ammo Acid Research , pp. 301-308
    • Ljebman, J.M.1    Bennett, D.A.2
  • 144
    • 0022995755 scopus 로고
    • 2-Amino-7-phosphonoheptanoic acid (AP7) produces discriminative stimuli and anticonflict effects similar to diazepam
    • Bennett DA, Amrick CL 2-Amino-7-phosphonoheptanoic acid (AP7) produces discriminative stimuli and anticonflict effects similar to diazepam. Life Sc/(1986) 39:2455-2461.
    • (1986) Life Sc , vol.39 , pp. 2455-2461
    • Bennett, D.A.1    Amrick, C.L.2
  • 145
    • 0024368628 scopus 로고
    • Anxiolytic properties of 1aminocyclopropanecarboxylic acid, a ligand at strychnineinsensitive glycine receptors
    • Trullas R, Jackson B, Skolnick P: Anxiolytic properties of 1aminocyclopropanecarboxylic acid, a ligand at strychnineinsensitive glycine receptors. Pharmacol Biochem Behav (1989) 34:313-316.
    • (1989) Pharmacol Biochem Behav , vol.34 , pp. 313-316
    • Trullas, R.1    Jackson, B.2    Skolnick, P.3
  • 146
    • 0025949947 scopus 로고
    • Effects of HA-966 on conflict, social interaction, and plus maze behaviors
    • Corbett R, Dunn R: Effects of HA-966 on conflict, social interaction, and plus maze behaviors. Drug DevRes (1991) 24:201-205.
    • (1991) Drug DevRes , vol.24 , pp. 201-205
    • Corbett, R.1    Dunn, R.2
  • 147
    • 0031974244 scopus 로고    scopus 로고
    • A characterization of the anxiolytic-like actions induced by the novel NMDA/glycine site antagonist, L701,324
    • Kotflinska J, Uljequist S: A characterization of the anxiolytic-like actions induced by the novel NMDA/glycine site antagonist, L701,324. Psychopharmacology(1998) 135:175-181.
    • (1998) Psychopharmacology , vol.135 , pp. 175-181
    • Kotflinska, J.1    Uljequist, S.2
  • 148
    • 0025971286 scopus 로고    scopus 로고
    • Anxiolytic effect in the elevated plus-maze of the NMDA receptor antagonistAP7 microinjected into the dorsal periaqueductal grey
    • Guimaraes FS, Carobrez AP, Deaguiar JC, Graeff FG: Anxiolytic effect in the elevated plus-maze of the NMDA receptor antagonistAP7 microinjected into the dorsal periaqueductal grey. Psychopharmacology(199ty 103:91-94.
    • Psychopharmacology199ty , vol.103 , pp. 91-94
    • Guimaraes, F.S.1    Carobrez, A.P.2    Deaguiar, J.C.3    Graeff, F.G.4
  • 149
    • 85047680591 scopus 로고
    • Effects of glycine or (±)-3-amino-1hydroxy-2-pyrrolidone microinjections along the rostrocaudal axis of the dorsal periaqueductal gray matter on rats' performance in the elevated plus-maze task
    • Teixeira KV, Carobrez AP: Effects of glycine or (±)-3-amino-1hydroxy-2-pyrrolidone microinjections along the rostrocaudal axis of the dorsal periaqueductal gray matter on rats' performance In the elevated plus-maze task. Behav Neurosci (1399) 113:196-203.
    • (1399) Behav Neurosci , vol.113 , pp. 196-203
    • Teixeira, K.V.1    Carobrez, A.P.2
  • 150
    • 0032834028 scopus 로고    scopus 로고
    • Pharmacological agents acting at subtypes of metabotropic glutamate receptors
    • Schoepp DO, Jane DE, Monn JA: Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology (1999)38:1431-1476.
    • (1999) Neuropharmacology , vol.38 , pp. 1431-1476
    • Schoepp, D.O.1    Jane, D.E.2    Monn, J.A.3
  • 151
    • 15644369847 scopus 로고    scopus 로고
    • Design, synthesis, and pharmacological characterization of +}-2aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): A potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties
    • Monn JA, Valu MJ. Massey SM, Wright RA, Salhoff CR, Johnson BG, Howe T, Alt CA, Rhodes GA, Robey RL, Griffey KR, Tizzano JP, Kallman MJ, Helton DR, Schoepp DD: Design, synthesis, and pharmacological characterization of (+}-2aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): a potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties. J Med Chem (1997) 40:528-537.
    • (1997) J Med Chem , vol.40 , pp. 528-537
    • Monn, J.A.1    Valu, M.J.2    Massey, S.M.3    Wright, R.A.4    Salhoff, C.R.5    Johnson, B.G.6    Howe, T.7    Alt, C.A.8    Rhodes, G.A.9    Robey, R.L.10    Griffey, K.R.11    Tizzano, J.P.12    Kallman, M.J.13    Helton, D.R.14    Schoepp, D.D.15
  • 152
    • 0031933951 scopus 로고    scopus 로고
    • Anxiolytic and side-effect profile of LY354740: A potent, highly selective, orally active agonist for group II metabotropic glutamate receptors
    • Heiton DR, Tizzano JP, Monn JA, Schoepp DD, Kallman MJ: Anxiolytic and side-effect profile of LY354740: a potent, highly selective, orally active agonist for group II metabotropic glutamate receptors. J Pharmacol Exp 7her(1998) 284:651-660.
    • (1998) J Pharmacol Exp 7her , vol.284 , pp. 651-660
    • Heiton, D.R.1    Tizzano, J.P.2    Monn, J.A.3    Schoepp, D.D.4    Kallman, M.J.5
  • 153
    • 0344980107 scopus 로고    scopus 로고
    • Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models
    • Klodzinska A, Chojnacka-Wojcik E, Palucha A, Branski P, Popik P, Pile A: Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models. Neuropharmacology (1999) 38:1831 -1839.
    • (1999) Neuropharmacology , vol.38 , pp. 1831-1839
    • Klodzinska, A.1    Chojnacka-Wojcik, E.2    Palucha, A.3    Branski, P.4    Popik, P.5    Pile, A.6
  • 154
    • 0342545860 scopus 로고    scopus 로고
    • Selective group II glutamate metabotropic receptor agonist LY354740 attenuates pentetrazole- And picrotoxin-induced seizures
    • Klodzinska A, Chojnacka-Wojcik E, Pile A: Selective group II glutamate metabotropic receptor agonist LY354740 attenuates pentetrazole- and picrotoxin-induced seizures. Pol J Pharmacol (1999)51:543-545.
    • (1999) Pol J Pharmacol , vol.51 , pp. 543-545
    • Klodzinska, A.1    Chojnacka-Wojcik, E.2    Pile, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.