메뉴 건너뛰기




Volumn 9, Issue 10, 2000, Pages 2215-2231

Drugs in development for social anxiety disorder: More to social anxiety than meets the SSRI

Author keywords

Agonists; Antagonists; Benzodiazepines; CCK; CRF; Dopamine; GABA; Glutamate; Monoamine oxidase inhibitors; Neuropeptides; Psychopharmacology; Serotonin blockers; Serotonin re uptake inhibitors; Social anxiety disorder; Social phobia; Substance P; Treatment

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ALPRAZOLAM; BENZODIAZEPINE; BUSPIRONE; CLONAZEPAM; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; DOPAMINE; FLUVOXAMINE; GABAPENTIN; IMIPRAMINE; MOCLOBEMIDE; MONOAMINE OXIDASE A INHIBITOR; MONOAMINE OXIDASE INHIBITOR; NORADRENALIN; PAROXETINE; PHENELZINE; PLACEBO; PREGABALIN; PROPRANOLOL; RELEASING FACTOR; SEROTONIN; SEROTONIN 1A ANTAGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; SUBSTANCE P ANTAGONIST; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG;

EID: 0033772519     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.9.10.2215     Document Type: Review
Times cited : (20)

References (176)
  • 1
    • 0007502311 scopus 로고
    • American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders. 4th ed. American Psychiatric Press, Washington USA
    • (1994) , pp. 411-417
  • 5
    • 4243909442 scopus 로고
    • The prevalence of school dropouts in an anxiety disorders clinic
    • 48th Annual Meeting of the American Psychiatric Association. Miami, USA
    • (1995)
    • Van Ameringen, M.1    Mancini, C.2    Wilson, C.3
  • 6
    • 0000958112 scopus 로고
    • Cognitive behavioural treatments: Literature review
    • Social Phobia: Diagnosis Assessment and Treatment. Heimberg RG, Liebowitz MR, Hope DA, Schneier FR (Eds.), Guilford Press New York, USA
    • (1995) , pp. 261-309
    • Heimberg, R.G.1    Juster, H.R.2
  • 14
    • 8244233845 scopus 로고    scopus 로고
    • The International Multicenter Clinical Trial Group on Moclobemide in Social Phobia: A Double-Blind, Placebo-Controlled Study.
    • (1997) Eur. Arch. Psychiatry Clin. Neurosci. , vol.247 , pp. 71-80
  • 23
    • 4243797031 scopus 로고    scopus 로고
    • Treatment of generalized social phobia
    • 152nd Annual Meeting of the American Psychiatric Association. Washington, DC, USA
    • (1999)
    • Blomhoff, S.1    Haug, T.T.2    Humble, M.3
  • 26
    • 0007582686 scopus 로고    scopus 로고
    • Paroxetine in the treatment of social anxiety disorder (social phobia): An overview
    • Social Anxiety Disorder Study Group: 11th Congress of the European College of Neuropsychopharmacology (ECNP). Paris, France
    • (1998)
    • Baldwin, D.S.1    Smithkline Beecham2
  • 30
    • 0007575368 scopus 로고    scopus 로고
    • Imipramine in the treatment of social phobia: A double blind study
    • 36th Annual Meeting of the American College of Neuropsychopharmacology. Kamuela, Hawaii, USA
    • (1998)
    • Emmanuel, N.P.1    Johnson, M.2    Villareal, G.3
  • 33
    • 0008156845 scopus 로고
    • 3 antagonist, ondansetron, in social phobia
    • 33rd Annual Meeting of the American College of Neuropsychopharmacology. San Juan, Puerto Rico
    • (1994)
    • Bell, J.1    Deveaugh-Geiss, J.2
  • 51
    • 0007579306 scopus 로고    scopus 로고
    • CCK
    • Presentation at BAP summer meeting. Cambridge, UK
    • (1997)
    • Bradwejn, J.1
  • 52
    • 0027979078 scopus 로고
    • Anxiety and growth disturbance; is there a connection? A review of biological studies in social phobia
    • (1994) J. Clin. Psychol. , vol.55 , Issue.SUPPL. 6 , pp. 17-27
    • Uhde, T.1
  • 61
    • 0026544952 scopus 로고
    • Heart rate and plasma norepinephrine responsivity to orthostatic challenge in anxiety disorders: Comparison of patients with panic disorder and social phobia and normal control subjects
    • (1992) Arch. Gen. Psychiatry , vol.49 , pp. 311-317
    • Stein, M.B.1    Tancer, M.E.2    Uhde, T.W.3
  • 86
    • 0030606006 scopus 로고    scopus 로고
    • A computational approach to prefrontal cortex, cognitive control and schizophrenia: Recent developments and current challenges
    • Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences
    • (1996) , vol.351 , pp. 1515-1527
    • Cohen, J.D.1    Braver, T.S.2    O'Reilly, R.C.3
  • 96
    • 0001810636 scopus 로고
    • Descriptive psychopathology of social phobia
    • Social Phobia: Diagnosis and Treatment. Hemberg RG, Liebowitz MR. Hope DA. Schneier FR (Eds.), The Guilford Press, New York, USA
    • (1995) , pp. 41-66
    • Rapee, R.M.1
  • 98
    • 58149205351 scopus 로고
    • Development of inhibition during childhood: Evidence for situational specificity and a two-factor model
    • (1990) Dev. Psychology , vol.26 , pp. 721-730
    • Asendorpf, J.B.1
  • 100
    • 4243909381 scopus 로고
    • Two kinds of shyness
    • Self-related Cognitions in Anxiety and Motivation. Schwarzer R (Ed.), Lawrence Erlbaum Associates, Hillsdale, USA
    • (1995)
    • Buss, A.H.1
  • 101
    • 0003676791 scopus 로고
    • Temperament: Early developing personality traits
    • Lawrence Erlbaum Associates, Hillsdale, USA
    • (1984)
    • Buss, A.H.1    Plomin, R.2
  • 102
    • 0004060146 scopus 로고    scopus 로고
    • The emotional brain
    • Simon and Schuster, New York, USA
    • (1996)
    • Ledoux, J.1
  • 103
    • 0001934263 scopus 로고
    • The concept of behavioral inhibition to the familiar
    • Perspectives on Behavioral Inhibition. Reznick JS (Ed.), The University of Chicago Press, Chicago, USA
    • (1989) , pp. 1-23
    • Kagan, J.1
  • 104
    • 0001881314 scopus 로고
    • Social anxiety, evolution and self-presentation: An interdisciplinary perspective
    • Handbook of Social and Evaluation Anxiety. Leitenberg H (Ed.), Plenum Press, New York, USA
    • (1990) , pp. 11-45
    • Trower, P.1    Gilbert, P.2    Sherling, G.3
  • 105
    • 0001865119 scopus 로고    scopus 로고
    • The genetics and psychobiology of the seven-factor model of personality
    • Biology of Personality Disorders. Silk KR (Ed.), American Psychiatric Press, Washington, USA
    • (1998) , pp. 63-92
    • Cloninger, C.R.1
  • 106
    • 0004084439 scopus 로고
    • The neuropsychology of anxiety
    • Oxford University Press, Oxford, UK
    • (1982)
    • Gray, J.A.1
  • 109
    • 0028208756 scopus 로고
    • Beyond the serotonin reuptake inhibitors: Rationales for the development of new serotonergic agents
    • (1994) J. Clin. Psychiatry , vol.55 , Issue.SUPPL. 2 , pp. 34-44
    • Dubovsky, S.L.1
  • 112
    • 0007534687 scopus 로고    scopus 로고
    • Subordination and Social Defeat: An Evolutionary Approach to Mood Disorders and their Therapy. Lawrence Erlbaum Associates, Inc., Mahwah, NJ, USA
    • (2000)
    • Sloman, L.1    Gillbert, P.2
  • 114
    • 0003104204 scopus 로고    scopus 로고
    • Classical antidepressants, serotonin selective reuptake inhibitors and noradrenergic reuptake inhibitors
    • Essential Psychopharmacology, 2nd Ed. Stahl SM. (Ed.), Cambridge University Press, Cambridge, UK
    • (2000) , pp. 199-243
    • Stahl, S.M.1
  • 117
    • 0003328575 scopus 로고
    • BASF to merge boots pharma under knoll name
    • (1995) Scrip , vol.2014 , pp. 10
  • 120
    • 0023583966 scopus 로고
    • Neurotic inhibition and transnosographic approach. Apropos of a multicenter study of carpipramine
    • (1987) Encephale , vol.13 , Issue.6 , pp. 357-365
    • Ferreri, M.1    Alby, J.M.2
  • 121
    • 0007542201 scopus 로고    scopus 로고
    • Drug development pipeline: Irbesartan, clopidogrel, SR-90107, dronedarone, oxaliplatin, tirapazamine, rasuricase, xaliprodene, eplivansein, SR-31742, SR-90067, SR-58611, SR-48968, lintitript, SR-12187, SR-121463, SR-32701, SR-142948, osanetant, SR-141716, SR-48692, SR-144190, nolpitanium besilate, SR-146131, SR-34006
    • November 24.
    • (1997) Company Communication.
    • Sanofi, S.A.1
  • 122
    • 0003325094 scopus 로고    scopus 로고
    • Egis' Tensiomin tops Hungarian sales
    • (1996) Scrip , vol.2138 , pp. 8
  • 130
    • 0032977234 scopus 로고    scopus 로고
    • Is there a future for neuropeptide receptor ligands in the treatment of anxiety disorders?
    • (1999) Pharmacol. Ther. , vol.82 , Issue.1 , pp. 1-61
    • Griebel, G.1
  • 138
  • 142
    • 0007593388 scopus 로고    scopus 로고
    • Neurocrine announces that Janssen Pharmaceutical intends to replace R121919 with a back-up compound - Neurocrine CRF program on track for Phase I trials to begin 2nd half 2000 with unpartnered CRF antagonist for anxiety/depression
    • Neurocrine Biosciences Inc. April 05.
    • (2000) Press Release.
  • 143
    • 0007534689 scopus 로고    scopus 로고
    • Neurocrine announces its financial results for the year ended December 31, 1998
    • Neurocrine Biosciences Inc. March 5.
    • (1999) Press Release.
  • 144
    • 0019944850 scopus 로고
    • Neuropeptide Y - A novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide
    • (1982) Nature , vol.296 , Issue.5858 , pp. 659-660
    • Tatemoto, K.1    Carlquist, M.2    Mutt, V.3
  • 145
    • 0022617388 scopus 로고
    • Neuropeptide Y: Anatomical distribution and possible function in mammalian nervous system
    • (1986) Life Sci. , vol.38 , pp. 389-401
    • Gray, T.S.1    Morley, J.E.2
  • 152
    • 0032952090 scopus 로고    scopus 로고
    • Peptides and psychiatry part 3: Substance P and serendipity: Novel psychotropics are a possibility
    • (1999) J. Clin. Psychiatry , vol.60 , Issue.3 , pp. 40-141
    • Stahl, S.M.1
  • 154
    • 0000827107 scopus 로고
    • Behavioural effect of the NK2 antagonist SR 48968 but not of the NK1 antagonist SR 140333 in the mouse black and white box model
    • (Abstract).
    • (1995) Soc. Neurosci. , vol.21 , pp. 1696
    • Bernatzky, G.1    Saria, A.2
  • 162
    • 0007534141 scopus 로고    scopus 로고
    • Interneuron's Pagoclone significantly reduces panic attacks in Phase 2/3 clinical trial drug achieves primary endpoint, advances in clinical development
    • Interneurone Pharmaceuticals Inc. August 17.
    • (1998) Press Release
  • 163
    • 0003946045 scopus 로고    scopus 로고
    • Efficacy and safety of pagoclone in the treatment of panic disorder
    • And The Pagoclone Investigators Team: 40th Annual NCDEU Meeting. Boca Raton, FLA, USA
    • (2000)
    • Kavoussi, R.J.1    Pande, A.C.2
  • 164
    • 4243875084 scopus 로고    scopus 로고
    • Iddb meeting report
    • New Anti-epileptic Drugs - Fifth Eilat Conference. Eilat, Israel
    • (2000)
    • Perucca, E.1
  • 165
    • 0007540503 scopus 로고    scopus 로고
    • Drug development pipeline: Rolipram, SH-329, SH-470, SH-592, SH-543, levonorgestrel depot, Schering AG, SH-386, ZK-807191, azelaic acid, gadobutol, Sonovist, PTK-787, SH/TA-508, SH-U-555
    • February 24.
    • (1999) Company Communication
    • Schering, A.G.1
  • 173
    • 0032560495 scopus 로고    scopus 로고
    • Kainate receptors: An interplay between excitatory and inhibitory synapses
    • (1998) FEBS Lett. , vol.430 , pp. 100-104
    • Lerma, J.1
  • 175
    • 4243875083 scopus 로고    scopus 로고
    • Iddb meeting report
    • 26th National Medicinal Chemistry Symposium (Part III) Highlights of the poster presentations. Richmond, Virginia, USA
    • (1998)
    • Swords, B.1
  • 176
    • 4243797023 scopus 로고    scopus 로고
    • Iddb meeting report
    • Nicotinic Acetylcholine Receptors - IBC's Second International Symposium; Advances in Molecular Pharmacology and Drug Development. Annapolis, MD, USA
    • (1999)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.