Synthesis, pharmacology and therapeutic potential of 10-methoxypyrazino[1,2-a]indoles, partial agonists at the 5HT(2C) receptor

European Journal of Medicinal Chemistry

Volumn 32, Issue 3, 1997, Pages 253-261

  Bos M ^a   Jenck, F ^a   Martin, J R ^a   Moreau, J L ^a   Mutel, V ^a   Sleight, A J ^a   Widmer, U ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

5HT(2C) receptor; Partial agonist; Psychiatric disorder; Pyrazinoindole; Serotonin

Indexed keywords

INOSITOL PHOSPHATE; PARTIAL AGONIST; PYRAZINO[1,2 A]INDOLE DERIVATIVE; SEROTONIN 1C RECEPTOR; SEROTONIN AGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DEPRESSION; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; MALE; MONKEY; OBSESSION; ORAL DRUG ADMINISTRATION; PANIC; PSYCHOPHARMACOLOGY; RAT;

EID: 0030958204     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(97)83976-1     Document Type: Article

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